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Entry version 130 (02 Jun 2021)
Sequence version 1 (01 Nov 1995)
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Protein

SWI/SNF nucleosome remodeling complex component

Gene

C08B11.3

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi623 – 697RFX-type winged-helixPROSITE-ProRule annotationAdd BLAST75

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-3214858, RMTs methylate histone arginines
R-CEL-8939243, RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SWI/SNF nucleosome remodeling complex component
Alternative name(s):
ARID domain-containing protein C08B11.3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:C08B11.3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

WormBase

More...
WormBasei
C08B11.3 ; CE01473 ; WBGene00007433 ; swsn-7

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002006001 – 1244SWI/SNF nucleosome remodeling complex componentAdd BLAST1244

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q09441

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q09441

PeptideAtlas

More...
PeptideAtlasi
Q09441

PRoteomics IDEntifications database

More...
PRIDEi
Q09441

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q09441

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00007433, Expressed in multi-cellular organism and 5 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q09441, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
39618, 2 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1031, PBAF chromatin remodeling complex

Protein interaction database and analysis system

More...
IntActi
Q09441, 1 interactor

STRING: functional protein association networks

More...
STRINGi
6239.C08B11.3

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini24 – 116ARIDPROSITE-ProRule annotationAdd BLAST93

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni486 – 534DisorderedSequence analysisAdd BLAST49
Regioni556 – 583DisorderedSequence analysisAdd BLAST28
Regioni597 – 619DisorderedSequence analysisAdd BLAST23
Regioni1134 – 1244DisorderedSequence analysisAdd BLAST111

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi486 – 523Polar residuesSequence analysisAdd BLAST38
Compositional biasi1140 – 1235Polar residuesSequence analysisAdd BLAST96

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2312, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016138

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006903_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q09441

Identification of Orthologs from Complete Genome Data

More...
OMAi
DIMMCVY

Database of Orthologous Groups

More...
OrthoDBi
181026at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001606, ARID_dom
IPR036431, ARID_dom_sf
IPR016024, ARM-type_fold
IPR003150, DNA-bd_RFX
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01388, ARID, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00501, BRIGHT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46774, SSF46774, 1 hit
SSF48371, SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51011, ARID, 1 hit
PS51526, RFX_DBD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q09441-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESRKRKSEL EHYIDKLTDP PEKQRKMAEF YNSLRMFYKR RWNATLKLPH
60 70 80 90 100
VQGVEVNLYR LYDTVMALGG WQKVAASDKW SDIAEMFGCK DDILCGDHAI
110 120 130 140 150
KIIYMRYLSK FEQVETIGDV DDYVDNEMSR SRGRNATSFF ATNECPISNN
160 170 180 190 200
RMVQEYQHRD ERGQIINEPD YARLTKSLIS GLPNEIDFAM NVCMLLSHAG
210 220 230 240 250
PKQLRICHAP TLLTLLVAHT GVYDEDDETM ADMGKEWKRT TKHNFRDFWA
260 270 280 290 300
SSGVPLDMLM TFLDREIEAE YIDEDDQFFT GVSETFNVKD SRCWRLNQVT
310 320 330 340 350
TIIRNLSFEP ANRVTIVKTW PVMKFLIMCA SCKWSPLYVA ALDALSNLAT
360 370 380 390 400
DIDLTDKTLV YISQHAILRI ITDGIFSLDK FKLVRSLEIL TGLCGFEGNE
410 420 430 440 450
AIICDWLNSA TIAHIFEVVG VKDIMMCVYT LECLYQISEM GDTACDLISE
460 470 480 490 500
SPKAIQQLVS MATLEAVSFG PAGLAGMKVV EYQPSFTQGS NQQQNPHHSQ
510 520 530 540 550
GGHQLGHSNV RMGGLNHNQH HQQIGPPGAP GAAPMTVRQV IQNNLALQQV
560 570 580 590 600
QRENLNREQY STQSSQPHPP HTNVPPSPSI LAHHSSGLVQ QNGMKFDRRT
610 620 630 640 650
GNLPVRPIAP STNSGESQLE QLTEKWIRQN CVFEPAMSTP RGELYAAYVD
660 670 680 690 700
DLRNLYHSMS GSLAMFSGVM KNLYPDVNFR MAQNGIMIVA QGIRLIRPHR
710 720 730 740 750
LAPAASQSAS ESHPLMKKML TSEPKEENGV LINGHAVQES GAERIIKTEP
760 770 780 790 800
IRTDEPSVLI ESQEQSVPKK QNDINGEETD EVELNSKIVT PEKKSITNGT
810 820 830 840 850
VEVCQEPIQA SKLFDENYAN QIEGSEVSIE IREQFVNDTD NVKLESEKIN
860 870 880 890 900
GIICNGNSKV KKESMASRAA HIVAVAAACN GDLERMNVVS NGNDIEKEIE
910 920 930 940 950
KETEKVEEET NEEKNKEVVE TEVVDDAQES EKRKCVPPSS NPTDYMCDWD
960 970 980 990 1000
CCSIYYASPS HVLKHLSEEH VAEELRLLCR WNGCADPTPR NRWSLITHIQ
1010 1020 1030 1040 1050
DSHCNEAQLK AASQKRKEGG GIAPVRGAPR AEVISRDINN HPGYAKNAAF
1060 1070 1080 1090 1100
DAIRRHAFNF LSRELTDEAE GPVTKSIRLT SCLILRNLAR YSAEGRQKLR
1110 1120 1130 1140 1150
RHESHICWLA LSRLESAHAL SQLLSELHQA PAAEEEQQKM LSEVPSSASL
1160 1170 1180 1190 1200
SSMAGSSSQL PTVPDSPTSS VASAPMKEST SVSNKPTVHI NRMLNFSSLN
1210 1220 1230 1240
EKTPTSPQFT AGSSPHRHQP IQQHIPSQPS PLVQTTPVRA GAGI
Length:1,244
Mass (Da):139,117
Last modified:November 1, 1995 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i50FB3E4C13F73E06
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K5ATP7A0A2K5ATP7_CAEEL
SWI/SNF nucleosome remodeling compl...
swsn-7 C08B11.3, CELE_C08B11.3
1,201Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z46676 Genomic DNA Translation: CAA86663.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T19068

NCBI Reference Sequences

More...
RefSeqi
NP_495679.1, NM_063278.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C08B11.3a.1; C08B11.3a.1; WBGene00007433

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
174286

UCSC genome browser

More...
UCSCi
C08B11.3, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46676 Genomic DNA Translation: CAA86663.1
PIRiT19068
RefSeqiNP_495679.1, NM_063278.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi39618, 2 interactors
ComplexPortaliCPX-1031, PBAF chromatin remodeling complex
IntActiQ09441, 1 interactor
STRINGi6239.C08B11.3

PTM databases

iPTMnetiQ09441

Proteomic databases

EPDiQ09441
PaxDbiQ09441
PeptideAtlasiQ09441
PRIDEiQ09441

Genome annotation databases

EnsemblMetazoaiC08B11.3a.1; C08B11.3a.1; WBGene00007433
GeneIDi174286
UCSCiC08B11.3, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
174286
WormBaseiC08B11.3 ; CE01473 ; WBGene00007433 ; swsn-7

Phylogenomic databases

eggNOGiKOG2312, Eukaryota
GeneTreeiENSGT00390000016138
HOGENOMiCLU_006903_0_0_1
InParanoidiQ09441
OMAiDIMMCVY
OrthoDBi181026at2759

Enzyme and pathway databases

ReactomeiR-CEL-3214858, RMTs methylate histone arginines
R-CEL-8939243, RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q09441

Gene expression databases

BgeeiWBGene00007433, Expressed in multi-cellular organism and 5 other tissues
ExpressionAtlasiQ09441, baseline and differential

Family and domain databases

Gene3Di1.10.150.60, 1 hit
InterProiView protein in InterPro
IPR001606, ARID_dom
IPR036431, ARID_dom_sf
IPR016024, ARM-type_fold
IPR003150, DNA-bd_RFX
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01388, ARID, 1 hit
SMARTiView protein in SMART
SM00501, BRIGHT, 1 hit
SUPFAMiSSF46774, SSF46774, 1 hit
SSF48371, SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51011, ARID, 1 hit
PS51526, RFX_DBD, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSWSN7_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q09441
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 2, 2021
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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