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Entry version 114 (13 Nov 2019)
Sequence version 3 (23 Jan 2007)
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Protein

ATP-binding cassette sub-family C member 8

Gene

ABCC8

Organism
Cricetus cricetus (Black-bellied hamster)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive potassium channels and insulin release.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi713 – 720ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1379 – 1386ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor
Biological processTransport
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ATP-binding cassette sub-family C member 8
Alternative name(s):
Sulfonylurea receptor 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABCC8
Synonyms:SUR
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCricetus cricetus (Black-bellied hamster)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10034 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeCricetus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 34Extracellular1 PublicationAdd BLAST34
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei35 – 55Helical; Name=1Add BLAST21
Topological domaini56 – 75Cytoplasmic1 PublicationAdd BLAST20
Transmembranei76 – 96Helical; Name=2Add BLAST21
Topological domaini97 – 101Extracellular1 Publication5
Transmembranei102 – 122Helical; Name=3Add BLAST21
Topological domaini123 – 134Cytoplasmic1 PublicationAdd BLAST12
Transmembranei135 – 154Helical; Name=4Add BLAST20
Topological domaini155 – 167Extracellular1 PublicationAdd BLAST13
Transmembranei168 – 194Helical; Name=5Add BLAST27
Topological domaini195 – 311Cytoplasmic1 PublicationAdd BLAST117
Transmembranei312 – 331Helical; Name=6PROSITE-ProRule annotationAdd BLAST20
Topological domaini332 – 355ExtracellularBy similarityAdd BLAST24
Transmembranei356 – 376Helical; Name=7PROSITE-ProRule annotationAdd BLAST21
Topological domaini377 – 434CytoplasmicBy similarityAdd BLAST58
Transmembranei435 – 455Helical; Name=8PROSITE-ProRule annotationAdd BLAST21
Topological domaini456 – 458ExtracellularBy similarity3
Transmembranei459 – 479Helical; Name=9PROSITE-ProRule annotationAdd BLAST21
Topological domaini480 – 541CytoplasmicBy similarityAdd BLAST62
Transmembranei542 – 562Helical; Name=10PROSITE-ProRule annotationAdd BLAST21
Topological domaini563 – 584ExtracellularBy similarityAdd BLAST22
Transmembranei585 – 605Helical; Name=11PROSITE-ProRule annotationAdd BLAST21
Topological domaini606 – 1005Cytoplasmic1 PublicationAdd BLAST400
Transmembranei1006 – 1026Helical; Name=12Add BLAST21
Topological domaini1027 – 1073Extracellular1 PublicationAdd BLAST47
Transmembranei1074 – 1094Helical; Name=13PROSITE-ProRule annotationAdd BLAST21
Topological domaini1095 – 1138CytoplasmicBy similarityAdd BLAST44
Transmembranei1139 – 1159Helical; Name=14PROSITE-ProRule annotationAdd BLAST21
Topological domaini1160ExtracellularBy similarity1
Transmembranei1161 – 1181Helical; Name=15PROSITE-ProRule annotationAdd BLAST21
Topological domaini1182 – 1252CytoplasmicBy similarityAdd BLAST71
Transmembranei1253 – 1273Helical; Name=16PROSITE-ProRule annotationAdd BLAST21
Topological domaini1274 – 1277Extracellular1 Publication4
Transmembranei1278 – 1298Helical; Name=17Add BLAST21
Topological domaini1299 – 1582Cytoplasmic1 PublicationAdd BLAST284

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000933991 – 1582ATP-binding cassette sub-family C member 8Add BLAST1582

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi10N-linked (GlcNAc...) asparagine2 Publications1
Glycosylationi1050N-linked (GlcNAc...) asparagine1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q09427

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q09427

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with KCNJ11.

By similarity

Protein-protein interaction databases

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q09427

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q09427

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini299 – 602ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST304
Domaini679 – 930ABC transporter 1PROSITE-ProRule annotationAdd BLAST252
Domaini1013 – 1307ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST295
Domaini1345 – 1579ABC transporter 2PROSITE-ProRule annotationAdd BLAST235

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Family and domain databases

Database of protein disorder

More...
DisProti
DP01429

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1560.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR000844 ABCC8
IPR027417 P-loop_NTPase
IPR000388 Sulphorea_rcpt

The PANTHER Classification System

More...
PANTHERi
PTHR24223:SF187 PTHR24223:SF187, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01093 SULFNYLUR1
PR01092 SULFNYLUREAR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q09427-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPLAFCGTEN HSAAYRVDQG VLNNGCFVDA LNVVPHVFLL FITFPILFIG
60 70 80 90 100
WGSQSSKVHI HHSTWLHFPG HNLRWILTFI LLFVLVCEIA EGILSDGVTE
110 120 130 140 150
SRHLHLYMPA GMAFMAAITS VVYYHNIETS NFPKLLIALL IYWTLAFITK
160 170 180 190 200
TIKFVKFYDH AIGFSQLRFC LTGLLVILYG MLLLVEVNVI RVRRYIFFKT
210 220 230 240 250
PREVKPPEDL QDLGVRFLQP FVNLLSKGTY WWMNAFIKTA HKKPIDLRAI
260 270 280 290 300
AKLPIAMRAL TNYQRLCVAF DAQARKDTQS PQGARAIWRA LCHAFGRRLI
310 320 330 340 350
LSSTFRILAD LLGFAGPLCI FGIVDHLGKE NHVFQPKTQF LGVYFVSSQE
360 370 380 390 400
FLGNAYVLAV LLFLALLLQR TFLQASYYVA IETGINLRGA IQTKIYNKIM
410 420 430 440 450
HMSTSNLSMG EMTAGQICNL VAIDTNQLMW FFFLCPNLWT MPVQIIVGVI
460 470 480 490 500
LLYYILGVSA LIGAAVIILL APVQYFVATK LSQAQRTTLE HSNERLKQTN
510 520 530 540 550
EMLRGMKLLK LYAWESIFCS RVEVTRRKEM TSLRAFAVYT SISIFMNTAI
560 570 580 590 600
PIAAVLITFV GHVSFFKESD LSPSVAFASL SLFHILVTPL FLLSSVVRST
610 620 630 640 650
VKALVSVQKL SEFLSSAEIR EEQCAPREPA PQGQAGKYQA VPLKVVNRKR
660 670 680 690 700
PAREEVRDLL GPLQRLAPSM DGDADNFCVQ IIGGFFTWTP DGIPTLSNIT
710 720 730 740 750
IRIPRGQLTM IVGQVGCGKS SLLLATLGEM QKVSGAVFWN SNLPDSEGED
760 770 780 790 800
PSSPERETAA GSDIRSRGPV AYASQKPWLL NATVEENITF ESPFNKQRYK
810 820 830 840 850
MVIEACSLQP DIDILPHGDQ TQIGERGINL SGGQRQRISV ARALYQQTNV
860 870 880 890 900
VFLDDPFSAL DVHLSDHLMQ AGILELLRDD KRTVVLVTHK LQYLPHADWI
910 920 930 940 950
IAMKDGTIQR EGTLKDFQRS ECQLFEHWKT LMNRQDQELE KETVMERKAS
960 970 980 990 1000
EPSQGLPRAM SSRDGLLLDE EEEEEEAAES EEDDNLSSVL HQRAKIPWRA
1010 1020 1030 1040 1050
CTKYLSSAGI LLLSLLVFSQ LLKHMVLVAI DYWLAKWTDS ALVLSPAARN
1060 1070 1080 1090 1100
CSLSQECDLD QSVYAMVFTL LCSLGIVLCL VTSVTVEWTG LKVAKRLHRS
1110 1120 1130 1140 1150
LLNRIILAPM RFFETTPLGS ILNRFSSDCN TIDQHIPSTL ECLSRSTLLC
1160 1170 1180 1190 1200
VSALTVISYV TPVFLVALLP LAVVCYFIQK YFRVASRDLQ QLDDTTQLPL
1210 1220 1230 1240 1250
VSHFAETVEG LTTIRAFRYE ARFQQKLLEY TDSNNIASLF LTAANRWLEV
1260 1270 1280 1290 1300
CMEYIGACVV LIAAATSISN SLHRELSAGL VGLGLTYALM VSNYLNWMVR
1310 1320 1330 1340 1350
NLADMEIQLG AVKRIHALLK TEAESYEGLL APSLIPKNWP DQGKIQIQNL
1360 1370 1380 1390 1400
SVRYDSSLKP VLKHVNTLIS PGQKIGICGR TGSGKSSFSL AFFRMVDMFE
1410 1420 1430 1440 1450
GRIIIDGIDI AKLPLHTLRS RLSIILQDPV LFSGTIRFNL DPEKKCSDST
1460 1470 1480 1490 1500
LWEALEIAQL KLVVKALPGG LDAIITEGGE NFSQGQRQLF CLARAFVRKT
1510 1520 1530 1540 1550
SIFIMDEATA SIDMATENIL QKVVMTAFAD RTVVTIAHRV HTILSADLVM
1560 1570 1580
VLKRGAILEF DKPETLLSQK DSVFASFVRA DK
Length:1,582
Mass (Da):177,147
Last modified:January 23, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB7FFDFD8E7124BA4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L40623 mRNA Translation: AAA99201.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L40623 mRNA Translation: AAA99201.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5TWVelectron microscopy6.30B/D/F/H1-1582[»]
5YWBelectron microscopy5.20B/D/F/H1-1582[»]
6BAAelectron microscopy3.63E/F/G/H1-1582[»]
6PZ9electron microscopy3.65C1-1582[»]
6PZAelectron microscopy3.74C1-1582[»]
6PZBelectron microscopy4.55G1-1582[»]
6PZCelectron microscopy4.34H1-1582[»]
6PZIelectron microscopy4.50G1-1582[»]
SMRiQ09427
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

CORUMiQ09427

PTM databases

iPTMnetiQ09427

Proteomic databases

PRIDEiQ09427

Protocols and materials databases

ABCD curated depository of sequenced antibodies

More...
ABCDi
Q09427

Family and domain databases

DisProtiDP01429
Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR000844 ABCC8
IPR027417 P-loop_NTPase
IPR000388 Sulphorea_rcpt
PANTHERiPTHR24223:SF187 PTHR24223:SF187, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
PRINTSiPR01093 SULFNYLUR1
PR01092 SULFNYLUREAR
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiABCC8_CRICR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q09427
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: November 13, 2019
This is version 114 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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