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Entry version 137 (16 Oct 2019)
Sequence version 1 (01 Nov 1996)
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Protein
Submitted name:

4Fe-4S ferredoxin-type domain-containing protein

Gene

cid-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q09409

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
4Fe-4S ferredoxin-type domain-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:cid-1Imported
ORF Names:CELE_K10D2.3Imported, K10D2.3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

WormBase

More...
WormBasei
K10D2.3 ; CE02015 ; WBGene00019629 ; cid-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q09409

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q09409

PeptideAtlas

More...
PeptideAtlasi
Q09409

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00019629 Expressed in 5 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
Q09409, 1 interactor

STRING: functional protein association networks

More...
STRINGi
6239.K10D2.3

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q09409

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini967 – 9984Fe-4S ferredoxin-typeInterPro annotationAdd BLAST32

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 59DisorderedSequence analysisAdd BLAST59
Regioni1380 – 1425DisorderedSequence analysisAdd BLAST46

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi20 – 59PolarSequence analysisAdd BLAST40
Compositional biasi1382 – 1398PolarSequence analysisAdd BLAST17
Compositional biasi1399 – 1416PolyampholyteSequence analysisAdd BLAST18

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2277 Eukaryota
COG5260 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00970000196213

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q09409

Identification of Orthologs from Complete Genome Data

More...
OMAi
CSAPVGQ

Database of Orthologous Groups

More...
OrthoDBi
803033at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q09409

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017896 4Fe4S_Fe-S-bd
IPR002058 PAP_assoc
IPR013087 Znf_C2H2_type
IPR036875 Znf_CCHC_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03828 PAP_assoc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57756 SSF57756, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51379 4FE4S_FER_2, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q09409-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDEQRSGSR RRGGALGGGR GGNSQNSGRK RSSNSPADSA SSSQKTSRNP
60 70 80 90 100
SQNRPPMNIV PQKVTILKRN QDSQPTSPIN RNAPPGPLVA AVQPLMAVEL
110 120 130 140 150
GDSGASLKGW NSNPTTPEKT TINVAGRQAE ANKKQTQEYY FSKNAGSAVS
160 170 180 190 200
AQTFQETVQY PMSSFPLEKN VPIQIDNNFT LLITPTTSKC NGLFIKVKLQ
210 220 230 240 250
HGDDNITTGA LLKLDADEKT IRKSCRETIE NLLKAKSSSD RFPFSKCSEG
260 270 280 290 300
FLTSCLIKKL VDRLEAFPEA IYYCEKCDYH INTIGHAKAH LESSTHFDDV
310 320 330 340 350
KRQEQREHLL KIIPPPTEAH LESVEKVLEG TLKSYQQVRQ NGIEIGETII
360 370 380 390 400
YYLSTTVFPS IGLQDVILRP FGSVTYDVTL PDSDYNVAYT MSIPEGTPIF
410 420 430 440 450
ALLEQVRKKI ADDGHPADHS MEMGTPSTII FTFKGVRVKL CWMSCFNHRI
460 470 480 490 500
QLHFSELMKT YVNLREEVAQ FLQLIRLWAT KAGLDSKNKP RIGLPRYGFD
510 520 530 540 550
IMAIHFLQQI GCLPVLHELF EAGPETEKIE EMSAEKTAKL QSEEAGQRRM
560 570 580 590 600
RLMSRYEKNT EKIGTKFDLK KSWNLAELFI GFFRYYVERH RDVVIQITQL
610 620 630 640 650
IPMSRDVSRW NKKILHVVDP FRGDNVLSIP KVSTWQPFFF NCLLTSFVSF
660 670 680 690 700
SIPRTKNGPL IEVSFVHNKT IKPGKKFKDT PKKATVEAPI PLTQIMEEHY
710 720 730 740 750
QEPVYEIVND KDHLKYMKEL KERLMIDGIL VNERKPIDYH TDDHRECVYG
760 770 780 790 800
RNSLLRFKRV LKPGLNGKMA ASMDGLSFVT KKGKKFINRW KKANVIILSE
810 820 830 840 850
DSSEIDEKTK AADSNVSEIA EKLEETLKIS SQKNIDVAVT SMPVSTEIKP
860 870 880 890 900
EPITKLSNEA PVKIKNVAQP QCDLIEAPQE SLMNESMMES SFDETESPMK
910 920 930 940 950
TPIVQKPVKQ NATFGKSTIS TVIPDKQFCS EEFFIKLNSN LKDIVSKSKS
960 970 980 990 1000
LKPSDFHYEF STDLFCGDFE MEMKCTHCDG SHCVENCPMM EIPPIKKYQA
1010 1020 1030 1040 1050
RTPEDLKDID DMIDKYYHEN ILDERRLKML DHKIDELQSF LRKNYREDVT
1060 1070 1080 1090 1100
LTTFGSVMTG LSVNCSDIDI CLRFGDGDVP PKDLTAKEVI QKTESVLRKC
1110 1120 1130 1140 1150
HLVKRVQAIV TAKVPIVKFQ VKLSNGAIID VDISYYNILA IYNTALLKEY
1160 1170 1180 1190 1200
SLWTPDKRFA KLALFVKTWA KNCEIGDASR GSLSSYCHVI MLISYLQNCD
1210 1220 1230 1240 1250
PPVLPRLQED FRSDNRERRL VDNWDTSFAQ VETSLLQRWP KNKESCAQLL
1260 1270 1280 1290 1300
IGYFDYYSRF DFRNFVVQCR REMILSKMEK EWPRPLCVED PFDLSHNLSS
1310 1320 1330 1340 1350
GVNKKMFVFI MKVFINSRAV FMSEKPPMNR DHTFLSSYQH QLLRKCNQGS
1360 1370 1380 1390 1400
APTDRQCHQC HRIGHFVESC PQRALAKEAR KRFGSNSTNS SYRSNDSGRG
1410 1420
FKNGEEGGDR LTYHKRTYYH RSYNK
Length:1,425
Mass (Da):162,643
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5D8BD95833C32BA9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CCD72858.1

Protein sequence database of the Protein Information Resource

More...
PIRi
C88451

NCBI Reference Sequences

More...
RefSeqi
NP_498099.1, NM_065698.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
K10D2.3.1; K10D2.3.1; WBGene00019629

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
175707

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_K10D2.3

UCSC genome browser

More...
UCSCi
K10D2.3 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CCD72858.1
PIRiC88451
RefSeqiNP_498099.1, NM_065698.3

3D structure databases

SMRiQ09409
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ09409, 1 interactor
STRINGi6239.K10D2.3

Proteomic databases

EPDiQ09409
PaxDbiQ09409
PeptideAtlasiQ09409

Genome annotation databases

EnsemblMetazoaiK10D2.3.1; K10D2.3.1; WBGene00019629
GeneIDi175707
KEGGicel:CELE_K10D2.3
UCSCiK10D2.3 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
175707
WormBaseiK10D2.3 ; CE02015 ; WBGene00019629 ; cid-1

Phylogenomic databases

eggNOGiKOG2277 Eukaryota
COG5260 LUCA
GeneTreeiENSGT00970000196213
InParanoidiQ09409
OMAiCSAPVGQ
OrthoDBi803033at2759
PhylomeDBiQ09409

Enzyme and pathway databases

SignaLinkiQ09409

Gene expression databases

BgeeiWBGene00019629 Expressed in 5 organ(s), highest expression level in multi-cellular organism

Family and domain databases

InterProiView protein in InterPro
IPR017896 4Fe4S_Fe-S-bd
IPR002058 PAP_assoc
IPR013087 Znf_C2H2_type
IPR036875 Znf_CCHC_sf
PfamiView protein in Pfam
PF03828 PAP_assoc, 1 hit
SUPFAMiSSF57756 SSF57756, 1 hit
PROSITEiView protein in PROSITE
PS51379 4FE4S_FER_2, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ09409_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q09409
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 16, 2019
This is version 137 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
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