B4galnt2

Functionⁱ

Responsible for synthesis of murine T-lymphocyte CT antigen. Can transfer N-acetylgalactosamine moiety from UDP-GalNAc to the low molecular weight acceptor 3'-sialyl-N-acetyllactosamine, to form a non-reducing terminal tetrasaccharide Sda blood group structure.

Pathwayⁱ: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functionⁱ

acetylgalactosaminyltransferase activity
Source: UniProtKB
Inferred from sequence or structural similarityⁱ
- 14688233

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

lipid glycosylation Source: InterPro
negative regulation of cell-cell adhesion
Source: UniProtKB
Inferred from sequence or structural similarityⁱ
- 14688233
protein glycosylation
Source: MGI
Inferred from mutant phenotypeⁱ
- 9989502
UDP-N-acetylgalactosamine metabolic process
Source: UniProtKB
Inferred from sequence or structural similarityⁱ
- 14688233
UDP-N-acetylglucosamine metabolic process
Source: MGI
Inferred from mutant phenotypeⁱ
- 4031755
- 8137279

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Glycosyltransferase, Transferase

Molecular function

Glycosyltransferase, Transferase

Enzyme and pathway databases

Reactomeⁱ	R-MMU-446203 Asparagine N-linked glycosylation
UniPathwayⁱ	UPA00378

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GT12 Glycosyltransferase Family 12

CAZyⁱ

GT12 Glycosyltransferase Family 12

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Beta-1,4 N-acetylgalactosaminyltransferase 2 (EC:2.4.1.-)
Gene namesⁱ	Name:B4galnt2 Synonyms:Galgt2, Ggm3
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 11

Organism-specific databases

MGIⁱ	MGI:1342058 B4galnt2

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 15	CytoplasmicSequence analysisAdd BLAST	15
Transmembraneⁱ	16 – 32	Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST	17
Topological domainⁱ	33 – 510	LumenalSequence analysisAdd BLAST	478

Keywords - Cellular componentⁱ

Golgi apparatus, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000059104	1 – 510	Beta-1,4 N-acetylgalactosaminyltransferase 2Add BLAST		510

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Glycosylationⁱ	390	N-linked (GlcNAc...) asparagineSequence analysis		1

Keywords - PTMⁱ

Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q09199
PaxDbⁱ	Q09199
PRIDEⁱ	Q09199

PTM databases

iPTMnetⁱ	Q09199
PhosphoSitePlusⁱ	Q09199

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000013418
CleanExⁱ	MM_B4GALNT2
ExpressionAtlasⁱ	Q09199 baseline and differential
Genevisibleⁱ	Q09199 MM

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000037239

STRINGⁱ

10090.ENSMUSP00000037239

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q09199
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the glycosyltransferase 2 family.Curated

Keywords - Domainⁱ

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG410IF61 Eukaryota ENOG4111N56 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000006679
HOGENOMⁱ	HOG000220853
HOVERGENⁱ	HBG004812
InParanoidⁱ	Q09199
KEGG Orthology (KO) More...KOⁱ	K09655
OMAⁱ	YYTMPFG
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G04CW
PhylomeDBⁱ	Q09199
TreeFamⁱ	TF332297

Family and domain databases

Gene3Dⁱ	3.90.550.10, 1 hit
InterProⁱ	View protein in InterPro IPR001173 Glyco_trans_2-like IPR011143 GM2_synthase IPR029044 Nucleotide-diphossugar_trans
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00535 Glycos_transf_2, 1 hit
PIRSFⁱ	PIRSF000474 GM2_GD2_synthase, 1 hit
SUPFAMⁱ	SSF53448 SSF53448, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q09199-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTSSVSFASF RFPWLLKTFV LMVGLATVAF MVRKVSLTTD FSTFKPKFPE 
        60         70         80         90        100
PARVDPVLKL LPEEHLRKLF TYSDIWLFPK NQCDCNSGKL RMKYKFQDAY 
       110        120        130        140        150
NQKDLPAVNA RRQAEFEHFQ RREGLPRPPP LLAPPNLPFG YPVHGVEVMP 
       160        170        180        190        200
LHTILIPGLQ YEGPDAPVYE VILKASLGTL NTLADVPDDE VQGRGQRQLT 
       210        220        230        240        250
ISTRHRKVLN FILQHVTYTS TEYYLHKVDT VSMEYESSVA KFPVTIKQQT 
       260        270        280        290        300
VPKLYDPGPE RKIRNLVTIA TKTFLRPHKL KILLQSIRKY YPDITVIVAD 
       310        320        330        340        350
DSKEPLEIND DYVEYYTMPF GKGWFAGRNL AISQVTTKYV LWVDDDFLFS 
       360        370        380        390        400
DKTKIEVLVD VLEKTELDVV GGSVQGNTYQ FRLLYEQTKN GSCLHQRWGS 
       410        420        430        440        450
FQALDGFPGC TLTSGVVNFF LAHTEQLRRV GFDPILQRVA HGEFFIDGLG 
       460        470        480        490        500
RLLVGSCPGV IINHQVRTPP KDPKLAALEK TYDKYRANTN SVIQFKVALQ 
       510
YFKNHLYCST

Length:510

Mass (Da):58,317

Last modified:November 1, 1995 - v1

Checksum:ⁱ013783C80ADEC3CB

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L30104 mRNA Translation: AAA39802.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS25285.1
PIRⁱ	A53802
NCBI Reference Sequences More...RefSeqⁱ	NP_032107.1, NM_008081.3
UniGeneⁱ	Mm.340702

Genome annotation databases

Ensemblⁱ	ENSMUST00000038343; ENSMUSP00000037239; ENSMUSG00000013418
GeneIDⁱ	14422
KEGGⁱ	mmu:14422
UCSC genome browser More...UCSCⁱ	uc007lax.1 mouse

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
Q09199	Beta-1,4 N-acetylgalactosaminyltransferase		western European house mouse		510
Beta-1,4 N-acetylgalactosaminyltransferase		MOUSE		510
Beta-1,4 N-acetylgalactosaminyltransferase		MUSSP		510

Protein	Similar proteins		Species	Score	Length
Q09199	Beta-1,4 N-acetylgalactosaminyltransferase		western European house mouse		510
Beta-1,4 N-acetylgalactosaminyltransferase		MOUSE		510
Beta-1,4 N-acetylgalactosaminyltransferase		MUSSP		510
UPI000A30D2DC		MUSPA		510
UPI000A319623		MUSCR		510
+4

Protein	Similar proteins		Species	Score	Length
Q09199	Beta-1,4 N-acetylgalactosaminyltransferase 2		HUMAN		566
Beta-1,4-N-acetyl-galactosaminyltransferase 2		MACNE		578
Beta-1,4 N-acetylgalactosaminyltransferase		PONAB		566
Beta-1,4 N-acetylgalactosaminyltransferase		GORGO		565
Beta-1,4 N-acetylgalactosaminyltransferase		RHIBE		563
+148

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L30104 mRNA Translation: AAA39802.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS25285.1
PIRⁱ	A53802
NCBI Reference Sequences More...RefSeqⁱ	NP_032107.1, NM_008081.3
UniGeneⁱ	Mm.340702

3D structure databases

ProteinModelPortalⁱ	Q09199
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000037239

STRINGⁱ

10090.ENSMUSP00000037239

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GT12 Glycosyltransferase Family 12

CAZyⁱ

GT12 Glycosyltransferase Family 12

PTM databases

iPTMnetⁱ	Q09199
PhosphoSitePlusⁱ	Q09199

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q09199
PaxDbⁱ	Q09199
PRIDEⁱ	Q09199

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000038343; ENSMUSP00000037239; ENSMUSG00000013418
GeneIDⁱ	14422
KEGGⁱ	mmu:14422
UCSC genome browser More...UCSCⁱ	uc007lax.1 mouse

Organism-specific databases

CTDⁱ	124872
MGIⁱ	MGI:1342058 B4galnt2

Phylogenomic databases

eggNOGⁱ	ENOG410IF61 Eukaryota ENOG4111N56 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000006679
HOGENOMⁱ	HOG000220853
HOVERGENⁱ	HBG004812
InParanoidⁱ	Q09199
KEGG Orthology (KO) More...KOⁱ	K09655
OMAⁱ	YYTMPFG
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G04CW
PhylomeDBⁱ	Q09199
TreeFamⁱ	TF332297

Enzyme and pathway databases

UniPathwayⁱ	UPA00378
Reactomeⁱ	R-MMU-446203 Asparagine N-linked glycosylation

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q09199
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000013418
CleanExⁱ	MM_B4GALNT2
ExpressionAtlasⁱ	Q09199 baseline and differential
Genevisibleⁱ	Q09199 MM

Family and domain databases

Gene3Dⁱ	3.90.550.10, 1 hit
InterProⁱ	View protein in InterPro IPR001173 Glyco_trans_2-like IPR011143 GM2_synthase IPR029044 Nucleotide-diphossugar_trans
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00535 Glycos_transf_2, 1 hit
PIRSFⁱ	PIRSF000474 GM2_GD2_synthase, 1 hit
SUPFAMⁱ	SSF53448 SSF53448, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B4GN2_MOUSE
Accessionⁱ	Q09199Primary (citable) accession number: Q09199
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
	Last sequence update:	November 1, 1995
	Last modified:	July 5, 2017
	This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
PATHWAY comments
Index of metabolic and biosynthesis pathways
SIMILARITY comments
Index of protein domains and families

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q09199 (B4GN2_MOUSE)

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Beta-1,4 N-acetylgalactosaminyltransferase 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein glycosylation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Golgi apparatus

Golgi apparatus

Topology

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Functionⁱ

Pathwayⁱ: protein glycosylation

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ