UniProtKB - Q09188 (ADT_SCHPO)
Protein
ADP,ATP carrier protein
Gene
anc1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 100 | ADPBy similarity | 1 | |
Binding sitei | 112 | ADPBy similarity | 1 | |
Binding sitei | 257 | ADPBy similarity | 1 |
GO - Molecular functioni
- ATP:ADP antiporter activity Source: PomBase
GO - Biological processi
- mitochondrial ADP transmembrane transport Source: PomBase
- mitochondrial ATP transmembrane transport Source: PomBase
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: ADP,ATP carrier proteinAlternative name(s): ADP/ATP translocase Adenine nucleotide translocator Short name: ANT |
Gene namesi | Name:anc1 ORF Names:SPBC530.10c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:SPBC530.10c |
PomBasei | SPBC530.10c, anc1 |
Subcellular locationi
Mitochondrion
Mitochondrion
- mitochondrial inner membrane Source: PomBase
- mitochondrion Source: PomBase
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 27 – 54 | Helical; Name=1By similarityAdd BLAST | 28 | |
Transmembranei | 95 – 119 | Helical; Name=2By similarityAdd BLAST | 25 | |
Transmembranei | 128 – 148 | Helical; Name=3By similarityAdd BLAST | 21 | |
Transmembranei | 198 – 219 | Helical; Name=4By similarityAdd BLAST | 22 | |
Transmembranei | 233 – 253 | Helical; Name=5By similarityAdd BLAST | 21 | |
Transmembranei | 293 – 313 | Helical; Name=6By similarityAdd BLAST | 21 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000090592 | 1 – 322 | ADP,ATP carrier proteinAdd BLAST | 322 |
Proteomic databases
MaxQBi | Q09188 |
PaxDbi | Q09188 |
PRIDEi | Q09188 |
PTM databases
iPTMneti | Q09188 |
Interactioni
Subunit structurei
Homodimer.
By similarityProtein-protein interaction databases
BioGRIDi | 277416, 5 interactors |
IntActi | Q09188, 1 interactor |
STRINGi | 4896.SPBC530.10c.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 25 – 118 | Solcar 1Add BLAST | 94 | |
Repeati | 130 – 222 | Solcar 2Add BLAST | 93 | |
Repeati | 230 – 316 | Solcar 3Add BLAST | 87 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 257 – 262 | Important for transport activityBy similarity | 6 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 257 – 262 | Nucleotide carrier signature motifBy similarity | 6 |
Domaini
The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. At least 2 of the odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.By similarity
Sequence similaritiesi
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0749, Eukaryota |
HOGENOMi | CLU_015166_12_0_1 |
InParanoidi | Q09188 |
OMAi | KKYDGIA |
PhylomeDBi | Q09188 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR002113, ADT_euk_type IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
PANTHERi | PTHR45635, PTHR45635, 1 hit |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00927, ADPTRNSLCASE PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
i Sequence
Sequence statusi: Complete.
Q09188-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATSSAAAAA STPVNANTIT ETKNSTFFFD FMMGGVSAAV SKTAAAPIER
60 70 80 90 100
VKLLIQNQDE MIRAGRLSHR YKGIGECFKR TAAEEGVISL WRGNTANVLR
110 120 130 140 150
YFPTQALNFA FKDKFKKMFG YKKERDGYAK WFAGNLASGG AAGAASLLFV
160 170 180 190 200
YSLDYARTRL ANDAKSAKKG GERQFNGLVD VYRKTYRSDG LRGLYRGFGP
210 220 230 240 250
SVVGIVVYRG LYFGMYDTLK PVVLVGPLEG NFLASFLLGW AVTTGSGVAS
260 270 280 290 300
YPLDTIRRRM MMTSGEAVKY SSSFECGRQI LAKEGARSFF KGAGANILRG
310 320
VAGAGVLSIY DQVQLLMFGK KF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z49974 Genomic DNA Translation: CAA90275.1 CU329671 Genomic DNA Translation: CAA19176.1 D89102 mRNA Translation: BAA13765.1 |
PIRi | T40526 T42011 |
RefSeqi | NP_595323.1, NM_001021230.2 |
Genome annotation databases
EnsemblFungii | SPBC530.10c.1; SPBC530.10c.1:pep; SPBC530.10c |
GeneIDi | 2540900 |
KEGGi | spo:SPBC530.10c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z49974 Genomic DNA Translation: CAA90275.1 CU329671 Genomic DNA Translation: CAA19176.1 D89102 mRNA Translation: BAA13765.1 |
PIRi | T40526 T42011 |
RefSeqi | NP_595323.1, NM_001021230.2 |
3D structure databases
SMRi | Q09188 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 277416, 5 interactors |
IntActi | Q09188, 1 interactor |
STRINGi | 4896.SPBC530.10c.1 |
PTM databases
iPTMneti | Q09188 |
Proteomic databases
MaxQBi | Q09188 |
PaxDbi | Q09188 |
PRIDEi | Q09188 |
Genome annotation databases
EnsemblFungii | SPBC530.10c.1; SPBC530.10c.1:pep; SPBC530.10c |
GeneIDi | 2540900 |
KEGGi | spo:SPBC530.10c |
Organism-specific databases
EuPathDBi | FungiDB:SPBC530.10c |
PomBasei | SPBC530.10c, anc1 |
Phylogenomic databases
eggNOGi | KOG0749, Eukaryota |
HOGENOMi | CLU_015166_12_0_1 |
InParanoidi | Q09188 |
OMAi | KKYDGIA |
PhylomeDBi | Q09188 |
Miscellaneous databases
PROi | PR:Q09188 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR002113, ADT_euk_type IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
PANTHERi | PTHR45635, PTHR45635, 1 hit |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00927, ADPTRNSLCASE PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ADT_SCHPO | |
Accessioni | Q09188Primary (citable) accession number: Q09188 Secondary accession number(s): P78754 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families