Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 110 (02 Jun 2021)
Sequence version 1 (01 Nov 1996)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Cyclosporine synthetase

Gene

simA

Organism
Tolypocladium inflatum (Cyclosporin fungus) (Tolypocladium niveum)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLigaseARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Cyclosporine synthetaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:simAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTolypocladium inflatum (Cyclosporin fungus) (Tolypocladium niveum)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri29910 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesOphiocordycipitaceaeTolypocladium

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1060O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei2558O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei4045O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei5537O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei7034O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei8094O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei9589O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei11086O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei12158O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei13654O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei14729O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotationARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Molecular INTeraction database

More...
MINTi
Q09164

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1026 – 1100CarrierInterPro annotationAdd BLAST75
Domaini2524 – 2598CarrierInterPro annotationAdd BLAST75
Domaini4011 – 4085CarrierInterPro annotationAdd BLAST75
Domaini5503 – 5577CarrierInterPro annotationAdd BLAST75
Domaini7000 – 7074CarrierInterPro annotationAdd BLAST75
Domaini8060 – 8134CarrierInterPro annotationAdd BLAST75
Domaini9555 – 9629CarrierInterPro annotationAdd BLAST75
Domaini11052 – 11126CarrierInterPro annotationAdd BLAST75
Domaini12124 – 12198CarrierInterPro annotationAdd BLAST75
Domaini13620 – 13694CarrierInterPro annotationAdd BLAST75
Domaini14695 – 14769CarrierInterPro annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni15169 – 15224DisorderedSequence analysisAdd BLAST56

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2228 – 2252Sequence analysisAdd BLAST25
Coiled coili5216 – 5236Sequence analysisAdd BLAST21
Coiled coili9264 – 9288Sequence analysisAdd BLAST25
Coiled coili9680 – 9700Sequence analysisAdd BLAST21
Coiled coili10758 – 10778Sequence analysisAdd BLAST21
Coiled coili11177 – 11197Sequence analysisAdd BLAST21
Coiled coili12249 – 12269Sequence analysisAdd BLAST21
Coiled coili13745 – 13765Sequence analysisAdd BLAST21
Coiled coili14892 – 14912Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi15174 – 15224Polar residuesSequence analysisAdd BLAST51

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 11 hits
3.30.559.10, 12 hits
3.40.50.12780, 11 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010071, AA_adenyl_domain
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
IPR029063, SAM-dependent_MTases

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00501, AMP-binding, 11 hits
PF13193, AMP-binding_C, 4 hits
PF00668, Condensation, 12 hits
PF00550, PP-binding, 11 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00823, PKS_PP, 11 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336, SSF47336, 11 hits
SSF53335, SSF53335, 7 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01733, AA-adenyl-dom, 11 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00455, AMP_BINDING, 10 hits
PS50075, CARRIER, 11 hits
PS00012, PHOSPHOPANTETHEINE, 9 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q09164-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGAIGQDMAY DRLANPSRAS SISSNRYSEP VEQSFAQGRL WFLHQLKLGA
60 70 80 90 100
SWDITPAAIR LRGHLDIDAL NAASRALTQR HETLRTTFKE QDGVGVQVVH
110 120 130 140 150
ASGLERGLRI VDASSRDLAQ LLAEEQTMKF DLESEPAWRV ALLKVAEDHH
160 170 180 190 200
ILSIVVHHII SDSRSLDIIQ QELGELYTAA SQGKSISACP LGPIPIQYRD
210 220 230 240 250
LTTWQNQDEQ VAEQERQLGY WIEQLDNNTP AELLTELPRP AIPSGETGKI
260 270 280 290 300
SFQIDGSVHK ELLAFCRSQQ VTAYAVLLAA FRVAHFRLTG AEDATIGAPV
310 320 330 340 350
ANRDRPELEN MVAPLATLQC MRVVLDEDDT FESVLRQIMS VMTEAHANRD
360 370 380 390 400
VPFERIVSAL LPGSTDTSRH PLVQLMFALH PAQDTGRARW GFLEAETLQS
410 420 430 440 450
AAPTRFDMEM HLFEGDDRFD ANVLFSTGLF DAEAIRSVVS IFREVLRRGI
460 470 480 490 500
SEPAVHVKTM PLTDGLAAIR DMGLLDIGTT DYPREASVVD MFQEQVALNP
510 520 530 540 550
SATAVADASS RLSYSELDHK SDQLAAWLRR RQLKPETLIG VLSPPSCETM
560 570 580 590 600
VSFLGILKAH LAYLPLDINV PLARIESILS AVDGHKLVLL GSNVPQPKVD
610 620 630 640 650
VPDVELLRIS DALNGSQVNG LAGKQATAKP SATDLAYVIF TSGSTGKPKG
660 670 680 690 700
VMIEHRGIVR LVKGTNIISP AQAAVPTAHL ANIAFDLSTW EIYTPILNGG
710 720 730 740 750
TLVCIEHSVT LDSKALEAVF TKEGIRVAFL APALIKQCLA DRPAIFAGLD
760 770 780 790 800
SLYAIGDRFD RRDALHAKSL VKHGVYNAYG PTENSVVSTI YSVSEASPFV
810 820 830 840 850
TGVPVGRAIS NSGAYVMDQD QQLVSPGVMG ELVVSGDGLA RGYTDSALDK
860 870 880 890 900
NRFVVVQIDG ESIRGYRTGD RARYSLKGGQ IEFFGRMDQQ VKIRGHRIEP
910 920 930 940 950
AEVEHALLNS DQVRDAAVVI RRQEEEEPAM IAFVTTQGTL PDHLVNINGN
960 970 980 990 1000
GHVPDGNGSK NDQFAVHVES ELRRRLQMLL PSYMMPARIV VLDHLPLNPN
1010 1020 1030 1040 1050
GKVDRKALGQ SAKTVQKSKL VSQRVAPRNE IEAVLCEEYR SVLGVEVGIT
1060 1070 1080 1090 1100
DNFFDLGGHS LTAMKLAARI SQRLDIQASV ATVFEQPMLA DLAATIQRGS
1110 1120 1130 1140 1150
TLYSVIPTTE YTGPVEQSFA QGRLWFLEQL NTGASWYNVM LTVRLRGHLD
1160 1170 1180 1190 1200
VDALGTALLA LEKRHETLRT TFEERDGVGM QVVHSSLMGE LRLIDISEKS
1210 1220 1230 1240 1250
GTAAHEALMK EQSTRFDLTR EPGWRVALLK LADHHIFSIV MHHIVSDGWS
1260 1270 1280 1290 1300
LDLLRHELGQ LYSAALRGQD PLSRLEPLPI QYRDFAVWQK QDSQQKAAHQ
1310 1320 1330 1340 1350
RQLEYWTKQL ADSTPAELLT DFPRPSILSG KAGKVPVAIE GSLYDTLQVF
1360 1370 1380 1390 1400
SRTHQVTSFA VLLAAFRAAH FRLTGSDNAT IGVPSANRNR PELENVIGFF
1410 1420 1430 1440 1450
VNTQCIRITI DENDNFESLV RQVRSTTTAA QDNQDVPFEQ VVSSLMPSSS
1460 1470 1480 1490 1500
RDASRNPLVQ LMFALHGQQD LFKIQLEGTE EEVIPTEEVT RFDIEFHLYQ
1510 1520 1530 1540 1550
GASKLSGDII FAADLFEAET IRGVVSVFQE VLRRGLQQPQ TPIMTMPLTD
1560 1570 1580 1590 1600
GIPELERMGL LHMVKTDYPR NMSVVDVFQQ QVRLSAEATA VIDSSSRMSY
1610 1620 1630 1640 1650
AELDQRSDQV AAWLRQRQLP AETFVAVLAP RSCEAVIALF GILKAGHAYL
1660 1670 1680 1690 1700
PLDVNVPAAR LRAILAEVKG EKLVLLGAGE PSPEGQSPEV SIVRIADATS
1710 1720 1730 1740 1750
PAGHASLRDG KSKPTAGSLA YVIFTSGSTG KPKGVMIEHR GVLRLVKQTN
1760 1770 1780 1790 1800
ILSSLPPAQT FRMAHMSNLA FDASIWEVFT ALLNGGSLVC IDRFTILDAQ
1810 1820 1830 1840 1850
ALEALFLREH INIALFPPAL LKQCLTDAAA TIKSLDLLYV GGDRLDTADA
1860 1870 1880 1890 1900
ALAKALVKSE VYNAYGPTEN TVMSTLYSIA DTERFVNGVP IGRAVSNSGV
1910 1920 1930 1940 1950
YVMDQNQQLV PLGVMGELVV TGDGLARGYT NPALDSDRFV DVIARGQLLR
1960 1970 1980 1990 2000
AYRTGDRARY RPKDGQVEFF GRMDHQVKVR GHRIELAEVE HALLSSAGVH
2010 2020 2030 2040 2050
DAVVVSNSQE DNQGVEMVAF ITAQDNETLQ EAQSSNQVQE WESHFETTAY
2060 2070 2080 2090 2100
ADITAIDQNT LGRDFTSWTS MYDGTLIDKR EMQEWLDDTM RTFLDGQAAG
2110 2120 2130 2140 2150
HVLEIGTGTG MVLFNLGQAG LKSYIGLEPS QSAVQFVNKA AQTFPGLEGK
2160 2170 2180 2190 2200
AQVHVGTAMD TGRLSALSPD LIVINSVAQY FPSREYLAEV VEALVRIPGV
2210 2220 2230 2240 2250
RRIFFGDMRT YATHKDFLVA RAVHTNGSKV TRSKVQQEVA RLEELEEELL
2260 2270 2280 2290 2300
VDPAFFTSLK ESLSEEIEHV EILPKNMKVN NELSSYRYGA VLHIRNHNQN
2310 2320 2330 2340 2350
QSRSIHKINA ESWIDFASSQ MDRQGLARLL KENKDAESIA VFNIPYSKTI
2360 2370 2380 2390 2400
VERHIAKSLA DDHDGDDTHS SIDGVAWISA AREKASQCPS LDVHDLVQLA
2410 2420 2430 2440 2450
EDAGFRVEVS WARQRSQNGA LDVFFHHFQP TENESRALVD FPTDYKGQQA
2460 2470 2480 2490 2500
RSLTNRPLQR VESRRIEAQV REQLQVLLPA YMIPARIVVL QNMPLNTSGK
2510 2520 2530 2540 2550
VDRKELTLRA KVTAARTPSS ELVAPRDSIE AIICKEFKDV LGVEVGITDN
2560 2570 2580 2590 2600
FFNVGGHSLL ATKLAARLSR QLNAQIAVKD IFDRPVIADL AATIQQDTTE
2610 2620 2630 2640 2650
HNPILPTSYT GPVEQSFAQG RLWFLDQLNV GATWYLMPFA VRLRGPLVVS
2660 2670 2680 2690 2700
ALAAALLALE ERHETLRTTF IEQEGIGMQV IHPFAPKELR VIDVSGEEES
2710 2720 2730 2740 2750
TIQKILEKEQ TTPFNLASEP GFRLALLKTG EDEHILSTVM HHAISDGWSV
2760 2770 2780 2790 2800
DIFQQEIGQF YSAILRGHDP LAQIAPLSIQ YRDFATWQRQ IFQVAEHRRQ
2810 2820 2830 2840 2850
LAYWTKQLAD NKPAELLTDF KRPPMLSGRA GEIPVVVDGL IYEKLQDFCR
2860 2870 2880 2890 2900
IRQVTAFTVL LAAFRAAHYR MTGTEDATIG TPIANRNRPE LEGLIGFFVN
2910 2920 2930 2940 2950
TQCMRITVDV EDSFETLVHQ VRETTLAAHA NQDVPFEQIV SNILPGSSDT
2960 2970 2980 2990 3000
SRNPLVQLMF ALHSQQNLGK VRLEGIEEEI ISIAETTRFD IEFHLYQEAE
3010 3020 3030 3040 3050
RLNGSIVYAA DLFVPETIQS VITIFQGILQ KGLGEPDMPV ASMALDGGLE
3060 3070 3080 3090 3100
SLRSTGLLHP QQTDYPCDAS VVQIFKQQVA VNPDVIAVRD ESTRLSYADL
3110 3120 3130 3140 3150
DRKSDQVACW LSRRGIAPET FVAILAPRSC ETIVAILGVL KANLAYLPLD
3160 3170 3180 3190 3200
VNVPASRLEA ILSEVSGSML VLVGAETPIP EGMAEAETIR ITEILADAKT
3210 3220 3230 3240 3250
DDINGLAASQ PTAASLAYVI FTSGSTGRPK GVMVEHRGIV RLTKQTNITS
3260 3270 3280 3290 3300
KLPESFHMAH ISNLAFDASV WEVFTTLLNG GTLVCIDYFT LLESTALEKV
3310 3320 3330 3340 3350
FFDQRVNVAL LPPALLKQCL DNSPALVKTL SVLYIGGDRL DASDAAKARG
3360 3370 3380 3390 3400
LVQTQAFNAY GPTENTVMST IYPIAEDPFI NGVPIGHAVS NSGAFVMDQN
3410 3420 3430 3440 3450
QQITPPGAMG ELIVTGDGLA RGYTTSSLNT GRFINVDIDG EQVRAYRTGD
3460 3470 3480 3490 3500
RVRYRPKDLQ IEFFGRIDHQ VKIRGHRIEP AEVEYALLSH DLVTDAAVVT
3510 3520 3530 3540 3550
HSQENQDLEM VGFVAARVAD VREDESSNQV QEWQTHFDSI AYADITTIDQ
3560 3570 3580 3590 3600
QSLGRDFMSW TSMYDGSLIK KSQMQEWLDD TMRSLLDSQP PGHVLEVGTG
3610 3620 3630 3640 3650
TGMVLFNLGR EGGLQSYVGL EPSPSATAFV NKAAKSFPGL EDRIRVEVGT
3660 3670 3680 3690 3700
ATDIDRLGDD LHAGLVVVNS VAQYFPSQDY LAQLVRDLTK VPGVERIFFG
3710 3720 3730 3740 3750
DMRSHAINRD FLVARAVHAL GDKATKAEIQ REVVRMEESE DELLVDPAFF
3760 3770 3780 3790 3800
TSLTTQVENI KHVEILPKRM RATNELSSYR YAAVLHVNDL AKPAHKVSPG
3810 3820 3830 3840 3850
AWVDFAATKM DRDALIRLLR GTKISDHIAI ANIPNSKTIV ERTICESVYD
3860 3870 3880 3890 3900
LGGDAKDSND RVSWLSAARS NAVKVASLSA IDLVDIAQEA GFRVEISCAR
3910 3920 3930 3940 3950
QWSQNGALDA VFHHLGPSPQ SSHVLIDFLT DHQGRPEEAL TNHPLHRAQS
3960 3970 3980 3990 4000
RRVERQIRER LQTLLPAYMI PAQIMVLDKL PLNANGKVDR KQLTQRAQTV
4010 4020 4030 4040 4050
PKAKQVSAPV APRTEIERVL CQEFSDVLGV DIGIMENFFD LGGHSLMATK
4060 4070 4080 4090 4100
LAARISRRLE THVSVKEIFD HPRVCDLVLI VQQGSAPHDP IVSTKYTGPV
4110 4120 4130 4140 4150
PQSFAQGRLW FLDQLNFGAT WYLMPLAVRL RGAMNVHALT AALLALERRH
4160 4170 4180 4190 4200
ELLRTTFYEQ NGVGMQKVNP VVTETLRIID LSNGDGDYLP TLKKEQTAPF
4210 4220 4230 4240 4250
HLETEPGWRV ALLRLGPGDY ILSVVMHHII SDGWSVDVLF QELGQFYSTA
4260 4270 4280 4290 4300
VKGHDPLSQT TPLPIHYRDF ALWQKKPTQE SEHERQLQYW VEQLVDSAPA
4310 4320 4330 4340 4350
ELLTDLPRPS ILSGQAGEMS VTIEGALYKN LEEFCRVHRV TSFVVLLAAL
4360 4370 4380 4390 4400
RAAHYRLTGS EDATIGTPIA NRNRPELEQI IGFFVNTQCI RITVNEDETF
4410 4420 4430 4440 4450
ESLVQQVRST ATAAFAHQDV PFEKIVSTLL PGSRDASRNP LVQLMFAVHS
4460 4470 4480 4490 4500
QKNLGELKLE NAHSEVVPTE ITTRFDLEFH LFQQDDKLEG SILYSTDLFE
4510 4520 4530 4540 4550
AVSVQSLLSV FQEILRRGLN GPDVPISTLP LQDGIVDLQR QGLLDVQKTE
4560 4570 4580 4590 4600
YPRDSSVVDV FHEQVSINPD SIALIHGSEK LSYAQLDRES DRVARWLRHR
4610 4620 4630 4640 4650
SFSSDTLIAV LAPRSCETII AFLGILKANL AYLPLDVKAP AARIDAIVSS
4660 4670 4680 4690 4700
LPGNKLILLG ANVTPPKLQE AAIDFVPIRD TFTTLTDGTL QDGPTIERPS
4710 4720 4730 4740 4750
AQSLAYAMFT SGSTGRPKGV MVQHRNIVRL VKNSNVVAKQ PAAARIAHIS
4760 4770 4780 4790 4800
NLAFDASSWE IYAPLLNGGA IVCADYFTTI DPQALQETFQ EHEIRGAMLP
4810 4820 4830 4840 4850
PSLLKQCLVQ APDMISRLDI LFAAGDRFSS VDALQAQRLV GSGVFNAYGP
4860 4870 4880 4890 4900
TENTILSTIY NVAENDSFVN GVPIGSAVSN SGAYIMDKNQ QLVPAGVMGE
4910 4920 4930 4940 4950
LVVTGDGLAR GYMDPKLDAD RFIQLTVNGS EQVRAYRTGD RVRYRPKDFQ
4960 4970 4980 4990 5000
IEFFGRMDQQ IKIRGHRIEP AEVEQAFLND GFVEDVAIVI RTPENQEPEM
5010 5020 5030 5040 5050
VAFVTAKGDN SAREEEATTQ IEGWEAHFEG GAYANIEEIE SEALGYDFMG
5060 5070 5080 5090 5100
WTSMYDGTEI DKDEMREWLN DTMRSLLDGK PAGRVLEVGT GTGMIMFNLG
5110 5120 5130 5140 5150
RSQGLERYIG LEPAPSAAEF VNNAAKSFPG LAGRAEVHVG TAADVGTLQG
5160 5170 5180 5190 5200
LTSDMAVINS VAQYFPTPEY LAETIKSLVQ VPGMKRIYLG DMRSWAMNRD
5210 5220 5230 5240 5250
FAAARAAYSL ADNASKDRVR QKMMELEEKE EELLVDPAFF TALASQLQDR
5260 5270 5280 5290 5300
IQHVEILPKR MKATNELSSY RYAAVLHISD EPLPIYKIDP EAWINFEGSR
5310 5320 5330 5340 5350
LTREALAQVL KENENAESVA ISNIPYSKTV VERHIVRSLD QEDANAPEES
5360 5370 5380 5390 5400
MDGSDWISAV RTRAQQCHTL SASDLFDIAE DAGFRVEVSW ARQHSQHGAL
5410 5420 5430 5440 5450
DAVFHHLKPA TEDSRVLIKF PTDHQGRPLK SLTNQPLLPA QSRRAELLIR
5460 5470 5480 5490 5500
EGLQTLLPPY MIPSQITLID RMPLNANGKV DRRELARRAK ITQKSKPVED
5510 5520 5530 5540 5550
IVPPRNSVEA TVCKGFTDVL GVEVGITDNF FNLGGHSLMA TKLAARLGRQ
5560 5570 5580 5590 5600
LNTRISVRDV FDQPVVADLA AVIQRNSAPH EPIKPADYTG PVPQSFAQGR
5610 5620 5630 5640 5650
LWFLDQLNVG ATWYLMPLGI RLHGSLRVDA LATAISALEQ RHEPLRTTFH
5660 5670 5680 5690 5700
EEDGVGVQVV QDHRPKDLRI IDLSTQPKDA YLAVLKHEQT TLFDLATEPG
5710 5720 5730 5740 5750
WRVALIRLGE EEHILSIVMH HIISDGWSVE VLFDEMHRFY SSALRQQDPM
5760 5770 5780 5790 5800
EQILPLPIQY RDFAAWQKTE EQVAEHQRQL DYWTEHLADS TPAELLTDLP
5810 5820 5830 5840 5850
RPSILSGRAN ELPLTIEGRL HDKLRAFCRV HQATPFVILL AALRAAHYRL
5860 5870 5880 5890 5900
TGAEDATLGT PIANRNRPEL ENMIGFFVNT QCMRIAIEEN DNFESLVRRV
5910 5920 5930 5940 5950
RSTATSAFAN QDVPFESIVS SLLPGSRDAS RNPLVQVILA VHSQQDLGKL
5960 5970 5980 5990 6000
TLEGLRDEAV DSAISTRFDV EFHLFEHADR LSGSVLYAKE LFKLRTIESV
6010 6020 6030 6040 6050
VSVFLETLRR ALDQPLTPLA VLPLTDGVGE IASKGLLDVP RTDYPRDANI
6060 6070 6080 6090 6100
VEVFQQHVRA TPDAIAVKDA TSILTYAQLD QQSDRLAIWL SRRHMMPETL
6110 6120 6130 6140 6150
VGVLAPRSCE TIIAMFGIMK ANLAYLPLDI NSPAARLRSI LSAVDGNKLV
6160 6170 6180 6190 6200
LLGSGVTAPE QENPEVEAVG IQEILAGTGL DKTQGSNARP SATSLAYVIF
6210 6220 6230 6240 6250
TSGSTGKPKG VMVEHRSVTR LAKPSNVISK LPQGARVAHL ANIAFDASIW
6260 6270 6280 6290 6300
EIATTLLNGA TLVCLDYHTV LDCRTLKEVF ERESITVVTL MPALLKQCVA
6310 6320 6330 6340 6350
EIPETLAHLD LLYTGGDRVG GHDAMRARSL VKIGMFSGYG PTENTVISTI
6360 6370 6380 6390 6400
YEVDADEMFV NGVPIGKTVS NSGAYVMDRN QQLVPSGVVG ELVVTGDGLA
6410 6420 6430 6440 6450
RGYTDPSLNK NRFIYITVNG ESIRAYRTGD RVRYRPHDLQ IEFFGRMDQQ
6460 6470 6480 6490 6500
VKIRGHRIEP GEVESALLSH NSVQDAAVVI CAPADQDSGA EMVAFVAARN
6510 6520 6530 6540 6550
TEDEDTQEEE AVDQVQGWET HFETAAYSEV KDIRQSEVGN DFMGWTSMYD
6560 6570 6580 6590 6600
GSEIDKTDMH EWLNDTMRMI LDAREPGHVL EIGTGTGMVM FNLAKCPGLQ
6610 6620 6630 6640 6650
GYVGFEPSKS AAQFVNDAAQ SFPALKDGRS IVHVGTATDI NKAGPIQPRL
6660 6670 6680 6690 6700
VVINSVAQYF PTPEYLFRVV EALVQIPSVE RIVFGDMRTN AINRDFVASR
6710 6720 6730 6740 6750
ALHTLGEKAN KRLVRQMIYE LEANEEELLT DPAFFTSLRT RLGEKIKHVE
6760 6770 6780 6790 6800
ILPKTMKATN ELSKYRYAAV LHVRGSREQS TIHQVSPNAW IDFAADGLDR
6810 6820 6830 6840 6850
QTLINLLKEH KDAGTVAIGN IPYSKTIVER FVNKSLSEDD MEEGQNSLDG
6860 6870 6880 6890 6900
SAWVAAVRMA AQSCPSLDAM DVKEIAQEAG YQVEVSWARQ WSQNGALDAI
6910 6920 6930 6940 6950
FHHFEPPKEG ARTLIEFPTD YEGRNVNTLT NRPLNSIQSR RLGTQIREKL
6960 6970 6980 6990 7000
QTLLPPYMIP SRIMVLDQMP VNNNGKIDRK ELVRRAIVAP KPRSAATRVA
7010 7020 7030 7040 7050
PRNEIEAILR DEFEDVLGTE VSVLDNFFDL GGHSLMATKL AARVSRRLDA
7060 7070 7080 7090 7100
HISIKDVFDQ PVLADLAASI QRESAPHEPI PQRPYTGPAE QSFAQGRLWF
7110 7120 7130 7140 7150
LDQLNLGATW YLMPLAIRIR GQLRVAALSA ALFALERRHE TLRTTFEESD
7160 7170 7180 7190 7200
GVGVQIVGEA RNSDLRVHDV STGDDGEYLE VLRREQTVPF DLSSEPGWRV
7210 7220 7230 7240 7250
CLVKTGEEDH VLSIVMHHII YDGWSVDILR GELGQFYSAA LRGQDPLLHA
7260 7270 7280 7290 7300
NPLPIQYRDF AAWQREAKQV EEHQRQLGYW SKQLVDSTPA ELLTDLPRPS
7310 7320 7330 7340 7350
ILSGRAGSVD VTIEGSVYGA LQSFCRTRSV TTFVVLLTVF RIAHFRLTAV
7360 7370 7380 7390 7400
DDATIGTPIA NRNRPELETL VGCFVNTQCM RISIADDDNF EGLVRQVRNV
7410 7420 7430 7440 7450
ATAAYANQDV PFERIVSALV PGSRNTSRNP LVQLMFAVQS VEDYDQVRLE
7460 7470 7480 7490 7500
GLESVMMPGE ASTRFDMEFH LVPGDQKLTG SVLYSSDLFE QGTIQNFVDI
7510 7520 7530 7540 7550
FQECLRSVLD QPLTPISVLP FSNAISNLES LDLLEMPTSD YPRDRTVVDL
7560 7570 7580 7590 7600
FREQAAICPD SIAVKDSSSQ LTYAQLDEQS DRVAAWLHER HMPAESLVGV
7610 7620 7630 7640 7650
LSPRSCETII AYFGIMKANL AYLPLDVYAP DARLAAILDT VEGERLLLLG
7660 7670 7680 7690 7700
AGVPQPGIQI PRLSTAYIAE ALSHATTVDV TSIPQPSATS LAYVIFTSGS
7710 7720 7730 7740 7750
TGKPKGVMIE HRGIVRLVRD TNVNVFPESG SALPVSHFSN LAWDAATWEI
7760 7770 7780 7790 7800
YTAVLNGGTV VCIDRDTMLD IAALNSTFRK ENVRAAFFTP AFLKQCLAET
7810 7820 7830 7840 7850
PELVANLEIL HTAGDRLDPG DANLAGKTAK GGIFNVLGHT ENTAYSTFYP
7860 7870 7880 7890 7900
VVGEETFVNG VPVGRGISNS HAYIIDRHQK LVPAGVMGEL ILTGDGVARG
7910 7920 7930 7940 7950
YTDSALNKDR FVYIDINGKS TWSYRTGDKA RYRPRDGQLE FFGRMDQMVK
7960 7970 7980 7990 8000
IRGVRIEPGE VELTLLDHKS VLAATVVVRR PPNGDPEMIA FITIDAEDDV
8010 8020 8030 8040 8050
QTHKAIYKHL QGILPAYMIP SHLVILDQMP VTDNGKVDRK DLALRAQTVQ
8060 8070 8080 8090 8100
KRRSTAARVP PRDEVEAVLC EEYSNLLEVE VGITDGFFDL GGHSLLATKL
8110 8120 8130 8140 8150
AARLSRQLNT RVSVKDVFDQ PILADLADII RRGSHRHDPI PATPYTGPVE
8160 8170 8180 8190 8200
QSFAQGRLWF LEQLNLGASW YLMPFAIRMR GPLQTKALAV ALNALVHRHE
8210 8220 8230 8240 8250
ALRTTFEDHD GVGVQVIQPK SSQDLRIIDL SDAVDDTAYL AALKREQTTA
8260 8270 8280 8290 8300
FDLTSEPGWR VSLLRLGDDD YILSIVMHHI ISDGWTVDVL RQELGQFYSA
8310 8320 8330 8340 8350
AIRGQEPLSQ AKSLPIQYRD FAVWQRQENQ IKEQAKQLKY WSQQLADSTP
8360 8370 8380 8390 8400
CEFLTDLPRP SILSGEADAV PMVIDGTVYQ LLTDFCRTHQ VTSFSVLLAA
8410 8420 8430 8440 8450
FRTAHYRLTG TLDATVGTPI ANRNRPELEG LIGFFVNTQC MRMAISETET
8460 8470 8480 8490 8500
FESLVQQVRL TTTEAFANQD VPFEQIVSTL LPGSRDTSRN PLVQVMFALQ
8510 8520 8530 8540 8550
SQQDLGRIQL EGMTDEALET PLSTRLDLEV HLFQEVGKLS GSLLYSTDLF
8560 8570 8580 8590 8600
EVETIRGIVD VFLEILRRGL EQPKQRLMAM PITDGITKLR DQGLLTVAKP
8610 8620 8630 8640 8650
AYPRESSVID LFRQQVAAAP DAIAVWDSSS TLTYADLDGQ SNKLAHWLCQ
8660 8670 8680 8690 8700
RNMAPETLVA VFAPRSCLTI VAFLGVLKAN LAYLPLDVNA PAARIEAILS
8710 8720 8730 8740 8750
AVPGHKLVLV QAHGPELGLT MADTELVQID EALASSSSGD HEQIHASGPT
8760 8770 8780 8790 8800
ATSLAYVMFT SGSTGKPKGV MIDHRSIIRL VKNSDVVATL PTPVRMANVS
8810 8820 8830 8840 8850
NLAFDISVQE IYTALLNGGT LVCLDYLTLL DSKILYNVFV EAQVNAAMFT
8860 8870 8880 8890 8900
PVLLKQCLGN MPAIISRLSV LFNVGDRLDA HDAVAASGLI QDAVYNAYGP
8910 8920 8930 8940 8950
TENGMQSTMY KVDVNEPFVN GVPIGRSITN SGAYVMDGNQ QLVSPGVMGE
8960 8970 8980 8990 9000
IVVTGDGLAR GYTDSALDED RFVHVTIDGE ENIKAYRTGD RVRYRPKDFE
9010 9020 9030 9040 9050
IEFFGRMDQQ VKIRGHRIEP AEVEHALLGH DLVHDAAVVL RKPANQEPEM
9060 9070 9080 9090 9100
IAFITSQEDE TIEQHESNKQ VQGWGEHFDV SRYADIKDLD TSTFGHDFLG
9110 9120 9130 9140 9150
WTSMYDGVDI PVNEMKEWLD ETTASLLDNR PPGHILEIGA GTGMILSNLG
9160 9170 9180 9190 9200
KVDGLQKYVG LDPAPSAAIF VNEAVKSLPS LAGKARVLVG TALDIGSLDK
9210 9220 9230 9240 9250
NEIQPELVVI NSVAQYFPTS EYLIKVVKAV VEVPSVKRVF FGDIRSQALN
9260 9270 9280 9290 9300
RDFLAARAVR ALGDNASKEQ IREKIAELEE SEEELLVDPA FFVSLRSQLP
9310 9320 9330 9340 9350
NIKHVEVLPK LMKATNELSS YRYAAVLHIS HNEEEQLLIQ DIDPTAWVDF
9360 9370 9380 9390 9400
AATQKDSQGL RNLLQQGRDD VMIAVGNIPY SKTIVERHIM NSLDQDHVNS
9410 9420 9430 9440 9450
LDGTSWISDA RSAAAICTSF DAPALTQLAK EEGFRVELSW ARQRSQNGAL
9460 9470 9480 9490 9500
DAVFHRLATD ANCERSRVLV HFPTDHQGRQ LRTLTNRPLQ RAQSRRIESQ
9510 9520 9530 9540 9550
VFEALQTALP AYMIPSRIIV LPQMPTNANG KVDRKQLARR AQVVAKRKAV
9560 9570 9580 9590 9600
SARVAPRNDT EIVLCEEYAD ILGTEVGITD NFFDMGGHSL MATKLAARLS
9610 9620 9630 9640 9650
RRLDTRVTVK EVFDKPVLAD LAASIEQGST PHLPIASSVY SGPVEQSYAQ
9660 9670 9680 9690 9700
GRLWFLDQFN LNATWYHMSL AMRLLGPLNM DALDVALRAL EQRHETLRTT
9710 9720 9730 9740 9750
FEAQKDIGVQ VVHEAGMKRL KVLDLSDKNE KEHMAVLENE QMRPFTLASE
9760 9770 9780 9790 9800
PGWKGHLARL GPTEYILSLV MHHMFSDGWS VDILRQELGQ FYSAALRGRD
9810 9820 9830 9840 9850
PLSQVKPLPI QYRDFAAWQK EAAQVAEHER QLAYWENQLA DSTPGELLTD
9860 9870 9880 9890 9900
FPRPQFLSGK AGVIPVTIEG PVYEKLLKFS KERQVTLFSV LLTAFRATHF
9910 9920 9930 9940 9950
RLTGAEDATI GTPIANRNRP ELEHIIGFFV NTQCMRLLLD TGSTFESLVQ
9960 9970 9980 9990 10000
HVRSVATDAY SNQDIPFERI VSALLPGSRD ASRSPLIQLM FALHSQPDLG
10010 10020 10030 10040 10050
NITLEGLEHE RLPTSVATRF DMEFHLFQEP NKLSGSILFA DELFQPETIN
10060 10070 10080 10090 10100
SVVTVFQEIL RRGLDQPQVS ISTMPLTDGL IDLEKLGLLE IESSNFPRDY
10110 10120 10130 10140 10150
SVVDVFRQQV AANPNAPAVV DSETSMSYTS LDQKSEQIAA WLHAQGLRPE
10160 10170 10180 10190 10200
SLICVMAPRS FETIVSLFGI LKAGYAYLPL DVNSPAARIQ PILSEVEGKR
10210 10220 10230 10240 10250
LVLLGSGIDM PQSDRMDVET ARIQDILTNT KVERSDPMSR PSATSLAYVI
10260 10270 10280 10290 10300
FTSGSTGRPK GVMIEHRNIL RLVKQSNVTS QLPQDLRMAH ISNLAFDASI
10310 10320 10330 10340 10350
WEIFTAILNG GALICIDYFT LLDSQALRTT FEKARVNATL FAPALLKECL
10360 10370 10380 10390 10400
NHAPTLFEDL KVLYIGGDRL DATDAAKIQA LVKGTVYNAY GPTENTVMST
10410 10420 10430 10440 10450
IYRLTDGESY ANGVPIGNAV SSSGAYIMDQ KQRLVPPGVM GELVVSGDGL
10460 10470 10480 10490 10500
ARGYTNSTLN ADRFVDIVIN DQKARAYRTG DRTRYRPKDG SIEFFGRMDQ
10510 10520 10530 10540 10550
QVKIRGHRVE PAEVEQAMLG NKAIHDAAVV VQAVDGQETE MIGFVSMASD
10560 10570 10580 10590 10600
RFSEGEEEIT NQVQEWEDHF ESTAYAGIEA IDQATLGRDF TSWTSMYNGN
10610 10620 10630 10640 10650
LIDKAEMEEW LDDTMQSLLD KEDARPCAEI GTGTGMVLFN LPKNDGLESY
10660 10670 10680 10690 10700
VGIEPSRSAA LFVDKAAQDF PGLQGKTQIL VGTAEDIKLV KDFHPDVVVI
10710 10720 10730 10740 10750
NSVAQYFPSR SYLVQIASEL IHMTSVKTIF FGDMRSWATN RDFLVSRALY
10760 10770 10780 10790 10800
TLGDKATKDQ IRQEVARLEE NEDELLVDPA FFTSLTSQWP GKVKHVEILP
10810 10820 10830 10840 10850
KRMRTSNELS SYRYAAVLHI CRDGEGRNRY GRRVHSVEEN AWIDFASSGM
10860 10870 10880 10890 10900
DRHALVQMLD ERRDAKTVAI GNIPHSNTIN ERHFTTSLDT EGEGIAQDSL
10910 10920 10930 10940 10950
DGSAWQSATK AMAARCPCLS VTELVEIGQA AGFRVEVSWA RQRSQHGALD
10960 10970 10980 10990 11000
VVFHHLEDDR VGRVLINFPT DFERLPPSTG LTSRPLQRIQ NRRFESQIRE
11010 11020 11030 11040 11050
QLQTLLPPYM VPSRIVVLER MPLNANSKVD RKELARKART LQTIKPSATR
11060 11070 11080 11090 11100
VAPRNDIEAV LCDEFQAVLG VTVGVMDNFF ELGGHSLMAT KLAARLSRRL
11110 11120 11130 11140 11150
DTRVSVKDIF NQPILQDLAD VVQTGSAPHE AIPSTPYSGP VEQSFSQGRL
11160 11170 11180 11190 11200
WFLDQLNLNA SWYHMPLASR LRGPLRIEAL QSALATIEAR HESLRTTFEE
11210 11220 11230 11240 11250
QDGVPVQIVR AARNKQLRII DVSGTEDAYL AALKQEQDAA FDLTAEPGWR
11260 11270 11280 11290 11300
VALLRLGPDD HVLSIVMHHI ISDGWSVDIL RQELGQLYSN ASSQPAPLPI
11310 11320 11330 11340 11350
QYRDFAIWQK QDSQIAEHQK QLNYWKRQLV NSKPAELLAD FTRPKALSGD
11360 11370 11380 11390 11400
ADVIPIEIDD QVYQNLRSFC RARHVTSFVA LLAAFRAAHY RLTGAEDATI
11410 11420 11430 11440 11450
GSPIANRNRP ELEGLIGCFV NTQCLRIPVK SEDTFDTLVK QARETATEAQ
11460 11470 11480 11490 11500
DNQDVPFERI VSSMVASSRD TSRNPLVQVM FAVHSQHDLG NIRLEGVEGK
11510 11520 11530 11540 11550
PVSMAASTRF DAEMHLFEDQ GMLGGNVVFS KDLFESETIR SVVAVFQETL
11560 11570 11580 11590 11600
RRGLANPHAN LATLPLTDGL PSLRSLCLQV NQPDYPRDAS VIDVFREQVA
11610 11620 11630 11640 11650
SIPKSIAVID ASSQLTYTEL DERSSQLATW LRRQVTVPEE LVGVLAPRSC
11660 11670 11680 11690 11700
ETIIAFLGII KANLAYLPLD VNAPAGRIET ILSSLPGNRL ILLGSDTQAV
11710 11720 11730 11740 11750
KLHANSVRFT RISDALVESG SPPTEELSTR PTAQSLAYVM FTSGSTGVPK
11760 11770 11780 11790 11800
GVMVEHRGIT RLVKNSNVVA KQPAAAAIAH LSNIAFDASS WEIYAPLLNG
11810 11820 11830 11840 11850
GTVVCIDYYT TIDIKALEAV FKQHHIRGAM LPPALLKQCL VSAPTMISSL
11860 11870 11880 11890 11900
EILFAAGDRL SSQDAILARR AVGSGVYNAY GPTENTVLST IHNIGENEAF
11910 11920 11930 11940 11950
SNGVPIGNAV SNSGAFVMDQ NQQLVSAGVI GELVVTGDGL ARGYTDSKLR
11960 11970 11980 11990 12000
VDRFIYITLD GNRVRAYRTG DRVRHRPKDG QIEFFGRMDQ QIKIRGHRIE
12010 12020 12030 12040 12050
PAEVEQALAR DPAISDSAVI TQLTDEEEPE LVAFFSLKGN ANGTNGVNGV
12060 12070 12080 12090 12100
SDQEKIDGDE QHALLMENKI RHNLQALLPT YMIPSRIIHV DQLPVNANGK
12110 12120 12130 12140 12150
IDRNELAVRA QATPRTSSVS TYVAPRNDIE TIICKEFADI LSVRVGITDN
12160 12170 12180 12190 12200
FFDLGGHSLI ATKLAARLSR RLDTRVSVRD VFDTPVVGQL AASIQQGSTP
12210 12220 12230 12240 12250
HEAIPALSHS GPVQQSFAQG RLWFLDRFNL NAAWYIMPFG VRLRGPLRVD
12260 12270 12280 12290 12300
ALQTALRALE ERHELLRTTF EEQDGVGMQI VHSPRMRDIC VVDISGANED
12310 12320 12330 12340 12350
LAKLKEEQQA PFNLSTEVAW RVALFKAGEN HHILSIVMHH IISDGWSVDI
12360 12370 12380 12390 12400
FQQELAQFYS VAVRGHDPLS QVKPLPIHYR DFAVWQRQDK QVAVHESQLQ
12410 12420 12430 12440 12450
YWIEQLADST PAEILSDFNR PEVLSGEAGT VPIVIEDEVY EKLSLFCRNH
12460 12470 12480 12490 12500
QVTSFVVLLA AFRVAHYRLT GAEDATIGTP IANRNRPELE DLIGFFVNTQ
12510 12520 12530 12540 12550
CMRIALEEHD NFLSVVRRVR STAASAFENQ DVPFERLVSA LLPGSRDASR
12560 12570 12580 12590 12600
NPLVQLMFVV HSQRNLGKLQ LEGLEGEPTP YTATTRFDVE FHLFEQDKGL
12610 12620 12630 12640 12650
AGNVVFAADL FEAATIRSVV EVFHEILRRG LDQPDIAIST MPLVDGLAAL
12660 12670 12680 12690 12700
NSRNLPAVED IEPDFATEAS VVDVFQTQVV ANPDALAVTD TSTKLTYAEL
12710 12720 12730 12740 12750
DQQSDHVAAW LSKQKLPAES IVVVLAPRSS ETIVACIGIL KANLAYLPMD
12760 12770 12780 12790 12800
SNVPEARRQA ILSEIPGEKF VLLGAGVPIP DNKTADVRMV FISDIVASKT
12810 12820 12830 12840 12850
DKSYSPGTRP SASSLAYVIF TSGSTGRPKG VMVEHRGVIS LVKQNASRIP
12860 12870 12880 12890 12900
QSLRMAHVSN LAFDASVWEI FTTLLNGGTL FCISYFTVLD SKALSAAFSD
12910 12920 12930 12940 12950
HRINITLLPP ALLKQCLADA PSVLSSLESL YIGGDRLDGA DATKVKDLVK
12960 12970 12980 12990 13000
GKAYNAYGPT ENSVMSTIYT IEHETFANGV PIGTSLGPKS KAYIMDQDQQ
13010 13020 13030 13040 13050
LVPAGVMGEL VVAGDGLARG YTDPSLNTGR FIHITIDGKQ VQAYRTGDRV
13060 13070 13080 13090 13100
RYRPRDYQIE FFGRLDQQIK IRGHRIEPAE VEQALLSDSS INDAVVVSAQ
13110 13120 13130 13140 13150
NKEGLEMVGY ITTQAAQSVD KEEASNKVQE WEAHFDSTAY ANIGGIDRDA
13160 13170 13180 13190 13200
LGQDFLSWTS MYDGSLIPRE EMQEWLNDTM RSLLDNQPPG KVLEIGTGTG
13210 13220 13230 13240 13250
MVLFNLGKVE GLQSYAGLEP SRSVTAWVNK AIETFPSLAG SARVHVGTAE
13260 13270 13280 13290 13300
DISSIDGLRS DLVVINSVAQ YFPSREYLAE LTANLIRLPG VKRIFFGDMR
13310 13320 13330 13340 13350
TYATNKDFLV ARAVHTLGSN ASKAMVRQQV AKLEDDEEEL LVDPAFFTSL
13360 13370 13380 13390 13400
SDQFPDEIKH VEILPKRMAA TNELSSYRYA AVIHVGGHQM PNGEDEDKQW
13410 13420 13430 13440 13450
AVKDINPKAW VDFAGTRMDR QALLQLLQDR QRGDDVVAVS NIPYSKTIME
13460 13470 13480 13490 13500
RHLSQSLDDD EDGTSAVDGT AWISRTQSRA KECPALSVAD LIEIGKGIGF
13510 13520 13530 13540 13550
EVEASWARQH SQRGGLDAVF HRFEPPRHSG HVMFRFPTEH KGRSSSSLTN
13560 13570 13580 13590 13600
RPLHLLQSRR LEAKVRERLQ SLLPPYMIPS RITLLDQMPL TSNGKVDRKK
13610 13620 13630 13640 13650
LARQARVIPR SAASTLDFVA PRTEIEVVLC EEFTDLLGVK VGITDNFFEL
13660 13670 13680 13690 13700
GGHSLLATKL SARLSRRLDA GITVKQVFDQ PVLADLAASI LQGSSRHRSI
13710 13720 13730 13740 13750
PSLPYEGPVE QSFAQGRLWF LDQFNIDALW YLIPFALRMR GPLQVDALAA
13760 13770 13780 13790 13800
ALVALEERHE SLRTTFEERD GVGIQVVQPL RTTKDIRIID VSGMRDDDAY
13810 13820 13830 13840 13850
LEPLQKEQQT PFDLASEPGW RVALLKLGKD DHILSIVMHH IISDGWSTEV
13860 13870 13880 13890 13900
LQRELGQFYL AAKSGKAPLS QVAPLPIQYR DFAVWQRQEE QVAESQRQLD
13910 13920 13930 13940 13950
YWKKQLADSS PAELLADYTR PNVLSGEAGS VSFVINDSVY KSLVSFCRSR
13960 13970 13980 13990 14000
QVTTFTTLLA AFRAAHYRMT GSDDATIGTP IANRNRPELE NLIGCFVNTQ
14010 14020 14030 14040 14050
CMRITIGDDE TFESLVQQVR STTATAFENQ DVPFERIVST LSAGSRDTSR
14060 14070 14080 14090 14100
NPLVQLLFAV HSQQGLGRIQ LDGVVDEPVL STVSTRFDLE FHAFQEADRL
14110 14120 14130 14140 14150
NGSVMFATDL FQPETIQGFV AVVEEVLQRG LEQPQSPIAT MPLAEGIAQL
14160 14170 14180 14190 14200
RDAGALQMPK SDYPRNASLV DVFQQQAMAS PSTVAVTDST SKLTYAELDR
14210 14220 14230 14240 14250
LSDQAASYLR RQQLPAETMV AVLAPRSCET IIAFLAILKA NLAYMPLDVN
14260 14270 14280 14290 14300
TPSARMEAII SSVPGRRLIL VGSGVRHADI NVPNAKTMLI SDTVTGTDAI
14310 14320 14330 14340 14350
GTPEPLVVRP SATSLAYVIF TSGSTGKPKG VMVEHRAIMR LVKDSNVVTH
14360 14370 14380 14390 14400
MPPATRMAHV TNIAFDVSLF EMCATLLNGG TLVCIDYLTL LDSTMLRETF
14410 14420 14430 14440 14450
EREQVRAAIF PPALLRQCLV NMPDAIGMLE AVYVAGDRFH SRDARATQAL
14460 14470 14480 14490 14500
AGPRVYNAYG PTENAILSTI YNIDKHDPYV NGVPIGSAVS NSGAYVMDRN
14510 14520 14530 14540 14550
QQLLPPGVMG ELVVTGEGVA RGYTDASLDT DRFVTVTIDG QRQRAYRTGD
14560 14570 14580 14590 14600
RVRYRPKGFQ IEFFGRLDQQ AKIRGHRVEL GEVEHALLSE NSVTDAAVVL
14610 14620 14630 14640 14650
RTMEEEDPQL VAFVTTDHEY RSGSSNEEED PYATQAAGDM RKRLRSLLPY
14660 14670 14680 14690 14700
YMVPSRVTIL RQMPLNANGK VDRKDLARRA QMTPTASSSG PVHVAPRNET
14710 14720 14730 14740 14750
EAAICDEFET ILGVKVGITD NFFELGGHSL LATKLAARLS RRMGLRISVK
14760 14770 14780 14790 14800
DLFDDPVPVS LAGKLEQQQG FSGEDESSTV GIVPFQLLPA EMSREIIQRD
14810 14820 14830 14840 14850
VVPQIENGHS TPLDMYPATQ TQIFFLHDKA TGHPATPPLF SLDFPETADC
14860 14870 14880 14890 14900
RRLASACAAL VQHFDIFRTV FVSRGGRFYQ VVLAHLDVPV EVIETEQELD
14910 14920 14930 14940 14950
EVALALHEAD KQQPLRLGRA MLRIAILKRP GAKMRLVLRM SHSLYDGLSL
14960 14970 14980 14990 15000
EHIVNALHAL YSDKHLAQAP KFGLYMHHMA SRRAEGYNFW RSILQGSSMT
15010 15020 15030 15040 15050
SLKRSVGALE AMTPSAGTWQ TSKSIRIPPA ALKNGITQAT LFTAAVSLLL
15060 15070 15080 15090 15100
AKHTKSTDVV FGRVVSGRQD LSINCQDIVG PCINEVPVRV RIDEGDDMGG
15110 15120 15130 15140 15150
LLRAIQDQYT SSFRHETLGL QEVKENCTDW TDATKEFSCC IAFQNLNLHP
15160 15170 15180 15190 15200
EAEIEGQQIR LEGLPAKDQA RQANGHAPNG TNGTNGTNGT NGANGTNGTN
15210 15220 15230 15240 15250
GTNGTHANGI NGSNGVNGRD SNVVSAAGDQ APVHDLDIVG IPEPDGSVKI
15260 15270 15280
GIGASRQILG EKVVGSMLNE LCETMLALSR T
Length:15,281
Mass (Da):1,689,067
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE26DA7AA35324C05
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z28383 Genomic DNA Translation: CAA82227.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S45487, S41309

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z28383 Genomic DNA Translation: CAA82227.1
PIRiS45487, S41309

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

MINTiQ09164

Family and domain databases

Gene3Di1.10.1200.10, 11 hits
3.30.559.10, 12 hits
3.40.50.12780, 11 hits
InterProiView protein in InterPro
IPR010071, AA_adenyl_domain
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
IPR029063, SAM-dependent_MTases
PfamiView protein in Pfam
PF00501, AMP-binding, 11 hits
PF13193, AMP-binding_C, 4 hits
PF00668, Condensation, 12 hits
PF00550, PP-binding, 11 hits
SMARTiView protein in SMART
SM00823, PKS_PP, 11 hits
SUPFAMiSSF47336, SSF47336, 11 hits
SSF53335, SSF53335, 7 hits
TIGRFAMsiTIGR01733, AA-adenyl-dom, 11 hits
PROSITEiView protein in PROSITE
PS00455, AMP_BINDING, 10 hits
PS50075, CARRIER, 11 hits
PS00012, PHOSPHOPANTETHEINE, 9 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ09164_TOLIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q09164
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 2, 2021
This is version 110 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again