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Entry version 159 (16 Oct 2019)
Sequence version 3 (27 Jul 2011)
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Protein

Neutrophil cytosol factor 1

Gene

Ncf1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandLipid-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-1236973 Cross-presentation of particulate exogenous antigens (phagosomes)
R-MMU-3299685 Detoxification of Reactive Oxygen Species
R-MMU-4420097 VEGFA-VEGFR2 Pathway
R-MMU-5668599 RHO GTPases Activate NADPH Oxidases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Neutrophil cytosol factor 1
Short name:
NCF-1
Alternative name(s):
47 kDa neutrophil oxidase factor
NCF-47K
Neutrophil NADPH oxidase factor 1
p47-phox
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ncf1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:97283 Ncf1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000967631 – 390Neutrophil cytosol factor 1Add BLAST390

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei304PhosphoserineBy similarity1
Modified residuei321PhosphoserineBy similarity1
Modified residuei329PhosphoserineBy similarity1
Modified residuei346PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated by PRKCD; phosphorylation induces activation of NCF1 and NADPH oxidase activity.By similarity1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q09014

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q09014

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q09014

PeptideAtlas

More...
PeptideAtlasi
Q09014

PRoteomics IDEntifications database

More...
PRIDEi
Q09014

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q09014

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q09014

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q09014

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000015950 Expressed in 160 organ(s), highest expression level in bone marrow

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q09014 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q09014 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4.

Interacts (via C-terminus) with NCF2 (via the C-terminal SH3 domain).

Interacts with NCF4.

Interacts with CYBB.

Interacts (via the second SH3 domain) with CYBA.

Interacts with NOXA1.

Interacts with ADAM15.

Interacts with TRAF4.

Interacts with FASLG (By similarity).

Interacts with PARK7 (via C-terminus); the interaction is enhanced by LPS and modulates NCF1 phosphorylation and membrane translocation (PubMed:26021615).

By similarity1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
201701, 2 interactors

Database of interacting proteins

More...
DIPi
DIP-2665N

Protein interaction database and analysis system

More...
IntActi
Q09014, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000016094

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q09014

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 125PXPROSITE-ProRule annotationAdd BLAST122
Domaini156 – 215SH3 1PROSITE-ProRule annotationAdd BLAST60
Domaini226 – 285SH3 2PROSITE-ProRule annotationAdd BLAST60

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi211 – 254Asp/Glu-rich (highly acidic)Add BLAST44
Compositional biasi292 – 390Arg/Lys-rich (highly basic)Add BLAST99

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The PX domain mediates interaction with phosphatidylinositol 3,4-bisphosphate and other anionic phospholipids. In the autoinhibited, unphosphorylated state an intramolecular interaction with the C-terminal SH3 domain precludes phospholipid binding and interaction with CYBA. Phosphorylation disrupts the autoinhibited state (By similarity).By similarity

Keywords - Domaini

Repeat, SH3 domain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IRR3 Eukaryota
ENOG410YYZE LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160014

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000232124

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q09014

KEGG Orthology (KO)

More...
KOi
K08011

Identification of Orthologs from Complete Genome Data

More...
OMAi
LPHKISR

Database of Orthologous Groups

More...
OrthoDBi
1183210at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06887 PX_p47phox, 1 hit
cd12021 SH3_p47phox_1, 1 hit
cd12022 SH3_p47phox_2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1520.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015039 NADPH_oxidase_p47Phox_C
IPR035756 NCF1_SH3_1
IPR035757 NCF1_SH3_2
IPR032136 NECFESHC
IPR001655 P47PHOX
IPR001683 Phox
IPR036871 PX_dom_sf
IPR034909 PX_p47phox
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain

The PANTHER Classification System

More...
PANTHERi
PTHR15706:SF6 PTHR15706:SF6, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16621 NECFESHC, 1 hit
PF08944 p47_phox_C, 1 hit
PF00787 PX, 1 hit
PF00018 SH3_1, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00498 P47PHOX
PR00452 SH3DOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00312 PX, 1 hit
SM00326 SH3, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50044 SSF50044, 2 hits
SSF64268 SSF64268, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50195 PX, 1 hit
PS50002 SH3, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q09014-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDTFIRHIA LLGFEKRFIP SQHYVYMFLV KWQDLSEKVV YRKFTEIYEF
60 70 80 90 100
HKMLKEMFPI EAGEIHTENR VIPHLPAPRW FDGQRAAESR QGTLTEYFNG
110 120 130 140 150
LMGLPVKISR CPHLLDFFKV RPDDLKLPTD SQAKKPETYL VPKDGKNNVA
160 170 180 190 200
DITGPIILQT YRAIADYEKS SGTEMTVATG DVVDVVEKSE SGWWFCQMKT
210 220 230 240 250
KRGWVPASYL EPLDSPDEAE DPDPNYAGEP YVTIKAYAAV EEDEMSLSEG
260 270 280 290 300
EAIEVIHKLL DGWWVVRKGD ITGYFPSMYL QKAGEEITQA QRQIRGRGAP
310 320 330 340 350
PRRSTIRNAQ SIHQRSRKRL SQDTYRRNSV RFLQQRRRPG RPGPLSTDGT
360 370 380 390
KDNPSTPRVK PQPAVPPRPS SDLILHRCTE STKRKLTSAV
Length:390
Mass (Da):44,667
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC8EFAB953839CE9A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WH69F8WH69_MOUSE
Neutrophil cytosol factor 1
Ncf1
404Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R293S4R293_MOUSE
Neutrophil cytosol factor 1
Ncf1
377Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti161Y → H in AAA50469 (PubMed:8119734).Curated1
Sequence conflicti343 – 345GPL → RAA in AAA50469 (PubMed:8119734).Curated3
Sequence conflicti344P → Q in BAA25649 (PubMed:9490028).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L11455 mRNA Translation: AAA50469.1
AB002663 mRNA Translation: BAA25649.1
AF267747 Genomic DNA Translation: AAF90134.1
AK149668 mRNA Translation: BAE29014.1
AK149732 mRNA Translation: BAE29053.1
AK152386 mRNA Translation: BAE31174.1
AK162308 mRNA Translation: BAE36845.1
AK170462 mRNA Translation: BAE41812.1
AK171559 mRNA Translation: BAE42526.1
CH466529 Genomic DNA Translation: EDL19452.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS39298.1

NCBI Reference Sequences

More...
RefSeqi
NP_001272966.1, NM_001286037.1
NP_035006.3, NM_010876.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000111275; ENSMUSP00000106906; ENSMUSG00000015950
ENSMUST00000146354; ENSMUSP00000138121; ENSMUSG00000015950

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
17969

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:17969

UCSC genome browser

More...
UCSCi
uc008zvh.3 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L11455 mRNA Translation: AAA50469.1
AB002663 mRNA Translation: BAA25649.1
AF267747 Genomic DNA Translation: AAF90134.1
AK149668 mRNA Translation: BAE29014.1
AK149732 mRNA Translation: BAE29053.1
AK152386 mRNA Translation: BAE31174.1
AK162308 mRNA Translation: BAE36845.1
AK170462 mRNA Translation: BAE41812.1
AK171559 mRNA Translation: BAE42526.1
CH466529 Genomic DNA Translation: EDL19452.1
CCDSiCCDS39298.1
RefSeqiNP_001272966.1, NM_001286037.1
NP_035006.3, NM_010876.4

3D structure databases

SMRiQ09014
ModBaseiSearch...

Protein-protein interaction databases

BioGridi201701, 2 interactors
DIPiDIP-2665N
IntActiQ09014, 2 interactors
STRINGi10090.ENSMUSP00000016094

PTM databases

iPTMnetiQ09014
PhosphoSitePlusiQ09014
SwissPalmiQ09014

Proteomic databases

EPDiQ09014
MaxQBiQ09014
PaxDbiQ09014
PeptideAtlasiQ09014
PRIDEiQ09014

Genome annotation databases

EnsembliENSMUST00000111275; ENSMUSP00000106906; ENSMUSG00000015950
ENSMUST00000146354; ENSMUSP00000138121; ENSMUSG00000015950
GeneIDi17969
KEGGimmu:17969
UCSCiuc008zvh.3 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
653361
MGIiMGI:97283 Ncf1

Phylogenomic databases

eggNOGiENOG410IRR3 Eukaryota
ENOG410YYZE LUCA
GeneTreeiENSGT00940000160014
HOGENOMiHOG000232124
InParanoidiQ09014
KOiK08011
OMAiLPHKISR
OrthoDBi1183210at2759

Enzyme and pathway databases

ReactomeiR-MMU-1236973 Cross-presentation of particulate exogenous antigens (phagosomes)
R-MMU-3299685 Detoxification of Reactive Oxygen Species
R-MMU-4420097 VEGFA-VEGFR2 Pathway
R-MMU-5668599 RHO GTPases Activate NADPH Oxidases

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ncf1 mouse

Protein Ontology

More...
PROi
PR:Q09014

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000015950 Expressed in 160 organ(s), highest expression level in bone marrow
ExpressionAtlasiQ09014 baseline and differential
GenevisibleiQ09014 MM

Family and domain databases

CDDicd06887 PX_p47phox, 1 hit
cd12021 SH3_p47phox_1, 1 hit
cd12022 SH3_p47phox_2, 1 hit
Gene3Di3.30.1520.10, 1 hit
InterProiView protein in InterPro
IPR015039 NADPH_oxidase_p47Phox_C
IPR035756 NCF1_SH3_1
IPR035757 NCF1_SH3_2
IPR032136 NECFESHC
IPR001655 P47PHOX
IPR001683 Phox
IPR036871 PX_dom_sf
IPR034909 PX_p47phox
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PANTHERiPTHR15706:SF6 PTHR15706:SF6, 1 hit
PfamiView protein in Pfam
PF16621 NECFESHC, 1 hit
PF08944 p47_phox_C, 1 hit
PF00787 PX, 1 hit
PF00018 SH3_1, 2 hits
PRINTSiPR00498 P47PHOX
PR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00312 PX, 1 hit
SM00326 SH3, 2 hits
SUPFAMiSSF50044 SSF50044, 2 hits
SSF64268 SSF64268, 1 hit
PROSITEiView protein in PROSITE
PS50195 PX, 1 hit
PS50002 SH3, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNCF1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q09014
Secondary accession number(s): O70144, Q3UE58, Q9JI34
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: July 27, 2011
Last modified: October 16, 2019
This is version 159 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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