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Entry version 50 (10 Feb 2021)
Sequence version 1 (31 Oct 2006)
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Protein
Submitted name:

TraI protein (DNA helicase I)

Gene

traI

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
TraI protein (DNA helicase I)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:traIImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid pO86A1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 283TrwCInterPro annotationAdd BLAST274
Domaini575 – 626ssDNA_TraI_NInterPro annotationAdd BLAST52
Domaini633 – 712TraI_2BInterPro annotationAdd BLAST80
Domaini1434 – 1556TraIInterPro annotationAdd BLAST123

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014059, Conjug_relaxase_N
IPR014129, Conjug_relaxase_TraI
IPR009767, DNA_helicase_TraI
IPR027417, P-loop_NTPase
IPR040668, TraI_2B
IPR040987, TraI_N
IPR014862, TrwC

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18272, ssDNA_TraI_N, 1 hit
PF07057, TraI, 1 hit
PF18340, TraI_2B, 1 hit
PF08751, TrwC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02686, relax_trwC, 1 hit
TIGR02760, TraI_TIGR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q08JE3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLSFSVVKSA GSAGNYYTDK DNYYVLGSMG ERWAGQGAEQ LGLQGSVDKD
60 70 80 90 100
VFTRLLEGRL PDGADLSRMQ DGSNKHRPGY DLTFSAPKSV SMMAMLGGDK
110 120 130 140 150
RLIDAHNQAV DFAVRQVEAL ASTRVMTDGQ SETVLTGNLV MALFNHDTSR
160 170 180 190 200
DQDPQLHTHV VVANVTQHNG EWKTLSSDKV GKTGFSENVL ANRIAFGKIY
210 220 230 240 250
QSELRQRVEA LGYETEVVGK HGMWEMPGVP VEAFSSRSQA IREAVGEGAS
260 270 280 290 300
LKSRDVAALD TRKSKQHVDP EIRMAEWMQT LKETGFDIRA YRDAADQRAE
310 320 330 340 350
IRTQAPGPAS QDGPDVQQAV TQAIAGLSER KVQFTYTDVL ARTVGILPPE
360 370 380 390 400
NGVIERARVG IDEAISREQL IPLDREKGLF TSGIHVLDEL SVRALSRDIM
410 420 430 440 450
KQNRVTVHPE KSVPRTAGYS DAVSVLAQDR PSLAIVSGQG GAAGQRERVA
460 470 480 490 500
ELVMMAREQG REVQIIAADR RSQMNLKQDE RLSGELITGR RQLQDGMTFT
510 520 530 540 550
PGSTVIVDQG EKLSLKETLT LLDGAARHNV QILITDSGQR TGTGSALMSM
560 570 580 590 600
KEAGVNTYRW QGGEQRPATI ISEPDRNVRY ARLAGDFAAS VKAGEESVAQ
610 620 630 640 650
VSGVREQAIL TQSIRSELKT QGVLGHPEVT MTALSPVWLD SRSRYLRDMY
660 670 680 690 700
RPGMVMEQWN PETRSHDRYV IDRVTAQSHS LTLRNAQGET QVVRISSLDS
710 720 730 740 750
SWSLFRPEKM PVADGERLRV TGKIPGLRVS GGDRLQVASV SEDAMTVVVP
760 770 780 790 800
GRAEPATLPV ADSPFTALKL ENGWVETPGH SVSDSATVFA SVTQMAMDNA
810 820 830 840 850
TLNGLARSGR DVRLYSSLDE TRTAEKLARH PSFTVVSEQI KARAGETSLE
860 870 880 890 900
TAISLQKAGL HTPAQQAIHL ALPVLESKNL AFNMVDLLTE AKSFAAEGTG
910 920 930 940 950
CTELGGEINA QIKRGDLLYV DVAKGYGTGL LVSRASYEAE KSILRHILEG
960 970 980 990 1000
KEAVTPLMER VPGELMETLT SGQRAATRMI LETSDRFTVV QGYAGVGKTT
1010 1020 1030 1040 1050
QFRAVMSAVN MLPASERPRV VGLGPTHRAV GEMRSAGVDA QTLASFLHDT
1060 1070 1080 1090 1100
QLQQRSGETP DFSNTLFLLD ESSMVGNTDM ARAYALIAAG GGRAVASGDT
1110 1120 1130 1140 1150
DQLQAIAPGQ PFRLQQTRSA ADVVIMKEIV RQTPELREAV YSLINRDVER
1160 1170 1180 1190 1200
ALSGLESVKP SQVPRQEGAW APEHSVTEFS HSQEAKLAEA QQKAMLKGET
1210 1220 1230 1240 1250
FPDVPMTLYE AIVRDYTGRT PEAREQTLIV THLNEDRRVL NSMIHDAREK
1260 1270 1280 1290 1300
AGELGKEQVM VPVLNTANIR DGELRRLSTW ENNPDALALV DNVYHRIAGI
1310 1320 1330 1340 1350
SKDDGLITLE DAEGNTRLIS PREAVAEGVT LYTPDKIRVG TGDRMRFTKS
1360 1370 1380 1390 1400
DRERGYVANS VWTVTAVSGD SVTLSDGQQT RVIRPGQERA EQHIDLAYAI
1410 1420 1430 1440 1450
TAHGAQGASE TFAIALEGTE GNRKLMAGFE SAYVALSRMK QHVQVYTDNR
1460 1470 1480 1490 1500
QGWTDAINNA VQKGTAHDVF EPKPDREVMN AERLFSTARE LRDVAAGRAV
1510 1520 1530 1540 1550
LRQAGLAGGD SPARFIAPGR KYPQPYVALP AFDCNGRSAG IWLNPLTTDD
1560 1570 1580 1590 1600
GNGLRGFSGE GRVKGSGDAQ FVALQGSRNG ESLLADNMQD GVRIARDNPD
1610 1620 1630 1640 1650
SGVVVRIAGE GRPWNPGAIT GGRVWGDIPD SSVQPGAGNG EPVTAEVLAQ
1660 1670 1680 1690 1700
RQAEEAIRRE TERRADEIVR KMAENKPDLP DGKTEQAVRE IAGQERDRAD
1710 1720 1730 1740 1750
ITEREAALPE SVLRESQREQ EAVREVAREN LLQERLQQME RDMVHDLQKE

KTLGGD
Length:1,756
Mass (Da):191,659
Last modified:October 31, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9C3B25B4F82494A3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB255435 Genomic DNA Translation: BAF33994.1

NCBI Reference Sequences

More...
RefSeqi
WP_011666501.1, NZ_BFVO01000150.1
YP_788091.1, NC_008460.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB255435 Genomic DNA Translation: BAF33994.1
RefSeqiWP_011666501.1, NZ_BFVO01000150.1
YP_788091.1, NC_008460.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR014059, Conjug_relaxase_N
IPR014129, Conjug_relaxase_TraI
IPR009767, DNA_helicase_TraI
IPR027417, P-loop_NTPase
IPR040668, TraI_2B
IPR040987, TraI_N
IPR014862, TrwC
PfamiView protein in Pfam
PF18272, ssDNA_TraI_N, 1 hit
PF07057, TraI, 1 hit
PF18340, TraI_2B, 1 hit
PF08751, TrwC, 1 hit
SUPFAMiSSF52540, SSF52540, 2 hits
TIGRFAMsiTIGR02686, relax_trwC, 1 hit
TIGR02760, TraI_TIGR, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ08JE3_ECOLX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q08JE3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: February 10, 2021
This is version 50 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

PlasmidImported
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