Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CLIP-associating protein 2

Gene

Clasp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-2467813 Separation of Sister Chromatids
R-MMU-2500257 Resolution of Sister Chromatid Cohesion
R-MMU-5663220 RHO GTPases Activate Formins
R-MMU-68877 Mitotic Prometaphase

Names & Taxonomyi

Protein namesi
Submitted name:
CLIP-associating protein 2Imported
Gene namesi
Name:Clasp2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1923749 Clasp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000033392 Expressed in 265 organ(s), highest expression level in cerebral cortex

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini90 – 323TOGInterPro annotationAdd BLAST234
Domaini640 – 878TOGInterPro annotationAdd BLAST239
Domaini1044 – 1275TOGInterPro annotationAdd BLAST232

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1053 – 1077Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2956 Eukaryota
ENOG410ZMY0 LUCA
GeneTreeiENSGT00390000001762
HOGENOMiHOG000236347
HOVERGENiHBG079692

Family and domain databases

Gene3Di1.25.10.10, 3 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024395 CLASP_N_dom
IPR034085 TOG
PfamiView protein in Pfam
PF12348 CLASP_N, 1 hit
SMARTiView protein in SMART
SM01349 TOG, 3 hits
SUPFAMiSSF48371 SSF48371, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

Q08EB6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRLICKRIC DYKSFDDEES VDGNRPSSAA SAFKVPAPKT PGNPVSSARK
60 70 80 90 100
PGSAGGPKVG GPSKEGGAGA VDEDDFIKAF TDVPSVQIYS SRELEETLNK
110 120 130 140 150
IREILSDDKH DWDQRANALK KIRSLLVAGA AQYDCFFQHL RLLDGALKLS
160 170 180 190 200
AKDLRSQVVR EACITVAHLS TVLGNKFDHG AEAIVPTLFN LVPNSAKVMA
210 220 230 240 250
TSGCAAIRFI IRHTHVPRLI PLITSNCTSK SVPVRRRSFE FLDLLLQEWQ
260 270 280 290 300
THSLERHAAV LVETIKKGIH DADAEARVEA RKTYMGLRNH FPGEAETLYN
310 320 330 340 350
SLEPSYQKSL QTYLKSSGSV ASLPQSDRSS SSSQESLNRP FSSKWSTANP
360 370 380 390 400
STVAGRVSVG GSKANPLPGS LQRSRSDIDV NAAAGAKAHH AAGQAVRSGR
410 420 430 440 450
LGAGALNPGS YASLEDTSDK MDGTASDDGR VRAKLSTPLV AVGNAKTDSR
460 470 480 490 500
GRSRTKMVSQ SQPGSRSGSP GRVLTTTALS TVSSGAQRVL VNSASAQKRS
510 520 530 540 550
KIPRSQGCSR EASPSRLSVA RSSRIPRPSV SQGCSREASR ESSRDTSPVR
560 570 580 590 600
SFQPLGPGYG ISQSSRLSSS VSAMRVLNTG SDVEEAVADA LLLGDIRTKK
610 620 630 640 650
KPARRRYESY GMHSDDDANS DASSACSERS YSSRNGSIPT YMRQTEDVAE
660 670 680 690 700
VLNRCASSNW SERKEGLLGL QNLLKNQRTL SRVELKRLCE IFTRMFADPH
710 720 730 740 750
GKRVFSMFLE TLVDFIQVHK DDLQDWLFVL LTQLLKKMGA DLLGSVQAKV
760 770 780 790 800
QKALDITRES FPNDLQFNIL MRFTVDQTQT PSLKVKVAIL KYIETLAKQM
810 820 830 840 850
DPRDFTNSSE TRLAVSRVIT WTTEPKSSDV RKAAQSVLIS LFELNTPEFT
860 870 880 890 900
MLLGALPKTF QDGATKLLHN HLRNTGNGTQ SSMGSPLTRP TPRSPANWSS
910 920 930 940 950
PLTSPTNTSQ NTLSPSAFDY DTENMNSEDI YSSLRGVTEA IQNFSFRSQE
960 970 980 990 1000
DMSEPVRRDP KKEDGDTICS GPGMSDPRAG GDAADGSQPA LDNKASLLHS
1010 1020 1030 1040 1050
MPLHSSPRSR DYNPYNYSDS ISPFNKSALK EAMFDDDADQ FPDDLSLDHS
1060 1070 1080 1090 1100
DLVAELLKEL SNHNERIEER KIALYELMKL TQEESFSVWD EHFKTILLLL
1110 1120 1130 1140 1150
LETLGDKEPT IRALALKVLK EILRHQPARF KNYAELTVMK TLEAHKDPHK
1160 1170 1180 1190 1200
EVVRSAEEAA SVLATSISPE QCIKVLCPII QTADYPINLA AIKMQTKVIE
1210 1220 1230 1240 1250
RVSKETLNML LPEIMPGLIQ GYDNSESSVR KACVFCLVAV HAVIGDELKP
1260 1270 1280
HLSQLTGSKM KLLNLYIKRA QTGSAGADPT ADVSGQS
Length:1,287
Mass (Da):140,881
Last modified:October 31, 2006 - v1
Checksum:i0C261C04E5C76837
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8BRT1CLAP2_MOUSE
CLIP-associating protein 2
Clasp2 Kiaa0627
1,286Annotation score:
A0A1L1ST22A0A1L1ST22_MOUSE
CLIP-associating protein 2
Clasp2
600Annotation score:
Q8BSE7Q8BSE7_MOUSE
CLIP-associating protein 2
Clasp2
400Annotation score:
E9Q8N5E9Q8N5_MOUSE
CLIP-associating protein 2
Clasp2
1,286Annotation score:
F7DCH5F7DCH5_MOUSE
CLIP-associating protein 2
Clasp2
1,307Annotation score:
Q08EB5Q08EB5_MOUSE
CLIP-associating protein 2
Clasp2
1,304Annotation score:
A0A1L1SRY3A0A1L1SRY3_MOUSE
CLIP-associating protein 2
Clasp2
103Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107803 Genomic DNA No translation available.
AC167246 Genomic DNA No translation available.
BC117963 mRNA Translation: AAI17964.1
BC131791 mRNA Translation: AAI31792.1
RefSeqiNP_001075429.1, NM_001081960.1
NP_083909.2, NM_029633.2
UniGeneiMm.222272

Genome annotation databases

EnsembliENSMUST00000166734; ENSMUSP00000130201; ENSMUSG00000033392
GeneIDi76499
UCSCiuc009rwr.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107803 Genomic DNA No translation available.
AC167246 Genomic DNA No translation available.
BC117963 mRNA Translation: AAI17964.1
BC131791 mRNA Translation: AAI31792.1
RefSeqiNP_001075429.1, NM_001081960.1
NP_083909.2, NM_029633.2
UniGeneiMm.222272

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000166734; ENSMUSP00000130201; ENSMUSG00000033392
GeneIDi76499
UCSCiuc009rwr.2 mouse

Organism-specific databases

CTDi23122
MGIiMGI:1923749 Clasp2

Phylogenomic databases

eggNOGiKOG2956 Eukaryota
ENOG410ZMY0 LUCA
GeneTreeiENSGT00390000001762
HOGENOMiHOG000236347
HOVERGENiHBG079692

Enzyme and pathway databases

ReactomeiR-MMU-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-2467813 Separation of Sister Chromatids
R-MMU-2500257 Resolution of Sister Chromatid Cohesion
R-MMU-5663220 RHO GTPases Activate Formins
R-MMU-68877 Mitotic Prometaphase

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000033392 Expressed in 265 organ(s), highest expression level in cerebral cortex

Family and domain databases

Gene3Di1.25.10.10, 3 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024395 CLASP_N_dom
IPR034085 TOG
PfamiView protein in Pfam
PF12348 CLASP_N, 1 hit
SMARTiView protein in SMART
SM01349 TOG, 3 hits
SUPFAMiSSF48371 SSF48371, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ08EB6_MOUSE
AccessioniPrimary (citable) accession number: Q08EB6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: November 7, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again