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Protein
Submitted name:

Suppressor of cytokine signaling 4

Gene

socs4

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Submitted name:
Suppressor of cytokine signaling 4Imported
Gene namesi
Name:socs4Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-481718 socs4

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSXETG00000012209

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000026666

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini278 – 373SH2InterPro annotationAdd BLAST96
Domaini368 – 417SOCS boxInterPro annotationAdd BLAST50

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4566 Eukaryota
ENOG4111V4J LUCA
GeneTreeiENSGT00760000119136
HOGENOMiHOG000027791
HOVERGENiHBG054138
OMAiESCSDAE
OrthoDBiEOG091G0EQ0
TreeFamiTF321368

Family and domain databases

CDDicd10385 SH2_SOCS4, 1 hit
Gene3Di3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR028416 SOCS4
IPR022252 SOCS4/SOCS5_dom
IPR035864 SOCS4_SH2
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
PANTHERiPTHR44282:SF2 PTHR44282:SF2, 1 hit
PfamiView protein in Pfam
PF00017 SH2, 1 hit
PF12610 SOCS, 1 hit
PF07525 SOCS_box, 1 hit
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SM00253 SOCS, 1 hit
SM00969 SOCS_box, 1 hit
SUPFAMiSSF158235 SSF158235, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit
PS50225 SOCS, 1 hit

Sequencei

Sequence statusi: Complete.

Q08D28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAENIEDKLG ELDVRPKSSR SRSADRKDGY VWSGKKLTWL NKNGHSSDGD
60 70 80 90 100
TINVVEDEDC ATQSQERKHS CSSIELDLDR SCGHKILGRS LKQKLQDAVG
110 120 130 140 150
QCFPIKTCSN RHSSTLSSKR KIHISELMLD KCPFPPKSDL AYRWHLIKRH
160 170 180 190 200
TAPVSQTKGE WVINDGLDLD GKEIQVKDKN SDGGEDCLLD GHATPCKVNI
210 220 230 240 250
GNVESLGTKG SRSSKEDSDL DSDDEAVTLC SSSRKRNKPK WETDDESFQA
260 270 280 290 300
ETPPKYHTQI DYVHCLVPDL FQINNNPCYW GVMDRYAAEA LLEGKPEGTF
310 320 330 340 350
LLRDSAQEDY LFSVSFRRYS RSLHARIEQW NHNFSFDAHD PCVFHAPNVT
360 370 380 390 400
GLLEHYKDPS SCMFFEPLLS SPLNRTFPFT LQHICRAAIC TSTNYDGIDA
410 420 430
LPVPSSMKLY LKEYHYKSKV RVRRVDAPEQ RNMKQF
Length:436
Mass (Da):49,601
Last modified:October 31, 2006 - v1
Checksum:i7EF8EF14B75D39FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01063781 Genomic DNA No translation available.
AAMC01063782 Genomic DNA No translation available.
BC123971 mRNA Translation: AAI23972.1
RefSeqiXP_012823918.1, XM_012968464.2
UniGeneiStr.4993

Genome annotation databases

EnsembliENSXETT00000026666; ENSXETP00000026666; ENSXETG00000012209
GeneIDi549828

Similar proteinsi

Entry informationi

Entry nameiQ08D28_XENTR
AccessioniPrimary (citable) accession number: Q08D28
Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: April 25, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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