UniProtKB - Q08C21 (Q08C21_DANRE)
Protein
Submitted name:
A disintegrin and metallopeptidase domain 28
Gene
adam28
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- endopeptidase activity Source: GO_Central
- metalloendopeptidase activity Source: InterPro
- metallopeptidase activity Source: GO_Central
GO - Biological processi
- integrin-mediated signaling pathway Source: UniProtKB-KW
Keywordsi
Molecular function | IntegrinImported |
Protein family/group databases
MEROPSi | M12.150 |
Names & Taxonomyi
Protein namesi | Submitted name: A disintegrin and metallopeptidase domain 28Imported |
Gene namesi | Name:adam28Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Organism-specific databases
ZFINi | ZDB-GENE-060929-532, adam28 |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 22 | Sequence analysisAdd BLAST | 22 | |
ChainiPRO_5004166720 | 23 – 293 | Sequence analysisAdd BLAST | 271 |
Keywords - PTMi
Disulfide bondARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 200 – 293 | Peptidase M12BInterPro annotationAdd BLAST | 94 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 206 – 226 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysis, SignalSequence analysisPhylogenomic databases
OrthoDBi | 1464753at2759 |
PhylomeDBi | Q08C21 |
Family and domain databases
CDDi | cd04269, ZnMc_adamalysin_II_like, 1 hit |
Gene3Di | 3.40.390.10, 1 hit |
InterProi | View protein in InterPro IPR024079, MetalloPept_cat_dom_sf IPR001590, Peptidase_M12B IPR002870, Peptidase_M12B_N IPR034027, Reprolysin_adamalysin |
Pfami | View protein in Pfam PF01562, Pep_M12B_propep, 1 hit PF01421, Reprolysin, 1 hit |
PROSITEi | View protein in PROSITE PS50215, ADAM_MEPRO, 1 hit |
i Sequence
Sequence statusi: Complete.
Q08C21-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAQRHLMLWI FTLCVSLDPS VGHIHELHRK VYEIVRPIGL HDLQKRDLQS
60 70 80 90 100
RPDRVKYAMT LGGRDIEMHL QKNTGMLTKD YSETYYTEDG MLVTTTPADL
110 120 130 140 150
DLCYYHGKIL NDSASLVSMS TCDGLRGYFQ TAEQRVLIEP LSEDSDGDHA
160 170 180 190 200
AFKYEDVNEA TPRVCGVTNT TWDESGDGVP PRILKTRSRS SGPTLFQRQK
210 220 230 240 250
YNEFFLVADN REYKKLNSDL EKLRKRIFEI INFINNVYKE INTFVALTGF
260 270 280 290
EVWTDNDKIT VSAASGATLD SFTKWRNSDL IKRQRHDNAH LLT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC124447 mRNA Translation: AAI24448.1 |
RefSeqi | NP_001070186.1, NM_001076718.1 |
Genome annotation databases
GeneIDi | 767749 |
KEGGi | dre:767749 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC124447 mRNA Translation: AAI24448.1 |
RefSeqi | NP_001070186.1, NM_001076718.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
MEROPSi | M12.150 |
Genome annotation databases
GeneIDi | 767749 |
KEGGi | dre:767749 |
Organism-specific databases
CTDi | 10863 |
ZFINi | ZDB-GENE-060929-532, adam28 |
Phylogenomic databases
OrthoDBi | 1464753at2759 |
PhylomeDBi | Q08C21 |
Family and domain databases
CDDi | cd04269, ZnMc_adamalysin_II_like, 1 hit |
Gene3Di | 3.40.390.10, 1 hit |
InterProi | View protein in InterPro IPR024079, MetalloPept_cat_dom_sf IPR001590, Peptidase_M12B IPR002870, Peptidase_M12B_N IPR034027, Reprolysin_adamalysin |
Pfami | View protein in Pfam PF01562, Pep_M12B_propep, 1 hit PF01421, Reprolysin, 1 hit |
PROSITEi | View protein in PROSITE PS50215, ADAM_MEPRO, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q08C21_DANRE | |
Accessioni | Q08C21Primary (citable) accession number: Q08C21 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 31, 2006 |
Last sequence update: | October 31, 2006 | |
Last modified: | December 2, 2020 | |
This is version 91 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |