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Entry version 115 (11 Dec 2019)
Sequence version 1 (01 Nov 1996)
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Protein

Putative ISWI chromatin-remodeling complex subunit YPL216W

Gene

YPL216W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be required for the activity of an ISWI chromatin-remodeling complex.By similarity

Miscellaneous

Present with 3060 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:G3O-34105-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative ISWI chromatin-remodeling complex subunit YPL216W
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:YPL216W
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XVI

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
FungiDB:YPL216W

Saccharomyces Genome Database

More...
SGDi
S000006137 YPL216W

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002421611 – 1102Putative ISWI chromatin-remodeling complex subunit YPL216WAdd BLAST1102

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q08964

PRoteomics IDEntifications database

More...
PRIDEi
Q08964

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
35969, 80 interactors

Database of interacting proteins

More...
DIPi
DIP-3968N

Molecular INTeraction database

More...
MINTi
Q08964

STRING: functional protein association networks

More...
STRINGi
4932.YPL216W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q08964 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini23 – 131WACPROSITE-ProRule annotationAdd BLAST109
Domaini375 – 435DDTPROSITE-ProRule annotationAdd BLAST61

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili673 – 743Sequence analysisAdd BLAST71

Keywords - Domaini

Coiled coil

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q08964

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018501 DDT_dom
IPR028941 WHIM2_dom
IPR013136 WSTF_Acf1_Cbp146

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02791 DDT, 1 hit
PF10537 WAC_Acf1_DNA_bd, 1 hit
PF15613 WSD, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00571 DDT, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50827 DDT, 1 hit
PS51136 WAC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q08964-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVLLNRRKIQ PKEIGQSADS FSETPWVIKE SSERINDYDS DLKKLDFYKR
60 70 80 90 100
DIFTCEISGK DGLSYFKALK SEEQHREKVR YLLPKELRKA IANFANFSPI
110 120 130 140 150
RKVGHLVESA FQRFSNRFFI GDTVCLKTIQ KNALITYKEG EPNLVESPTI
160 170 180 190 200
ENNVTLFLVK DVFQSNGMME SEKGEISAPK LSLYLITECL NRESKGAALI
210 220 230 240 250
VGQNEIKRPE SHFSKFIIAC FLNEILIKVS NKEHAPWRVK QEYIERYDVN
260 270 280 290 300
PKCSPNMIDY LPDRMNSSSS ELYTPLTIPP ESDVEPADWK ETSETSETSE
310 320 330 340 350
TSLSKIKAID DEISVSFDHI YDNVNSLAYN DLKGTVDDKE LPFTGPSIPF
360 370 380 390 400
ENISYLDSSL EYKNIDQKWF KECSQFPTER LLVVYQFLSF FGRFIGLSHF
410 420 430 440 450
NFDQFLTTIK CTSPEALVDE YVKINFLKTY NSKGSFTNEK PRNEIYNQVT
460 470 480 490 500
SSNVSQREKA NVFNADESQR IPSNFTRNQK MRKFITDKST EFVMYSIFKG
510 520 530 540 550
KPLKNDDMEF QSYEKVNILY IDIVCSLMCL MTDNEPDWNC NLMDNWTEEK
560 570 580 590 600
RKEEGNKTEI DIAIEKCLNY GDTSWVKLLH NKNFSNGNWL ICLLGILQQN
610 620 630 640 650
THMIAYSDVA KCITKKILPL SMNFVNLGDE LWDNFRKRLS IKDKIDVLWV
660 670 680 690 700
LVDFASNFSS YIKELVDKVP KLCNGIRLKL DSAKKEYIKL KRQLKTLTKN
710 720 730 740 750
RVKLHSNVSM NRYGSDECKG KVNALKVKIA YLMEDIAFLE AKLIQSDIKR
760 770 780 790 800
LEILGKDRNG NRYYWMDSNG SSSAISEKNE ELYNCCFLWV QGPSEADINF
810 820 830 840 850
CLDVDVESLK KWELLAKAKG TAYATKEVFS IFRSTDGSYY QIAQGENFMI
860 870 880 890 900
INSNGILMRP TIPAFIDKKI ISETPEKLLL SHHQWAFFND IEDIHMLVDR
910 920 930 940 950
LDDLRENEGQ LKKALTSKMD RIEVSYKQQF KIKRRIECDE TFKKNHKLLK
960 970 980 990 1000
NNEFTFPELK RIETTCTSNG QHFSNMEKIS KKLSRTKNDL VLEAILKDVA
1010 1020 1030 1040 1050
HLGECERALL KKQQNLIYPL NFHFEQLRTI DLEFIVETKR KRQEDILTKL
1060 1070 1080 1090 1100
LNHQRYKHIS HVSGYGISSQ RVDKAAHLDV QGILEEIECQ LISRRREDEE

RN
Length:1,102
Mass (Da):128,133
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE457A8CE097255D6
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z73572 Genomic DNA Translation: CAA97931.1
BK006949 Genomic DNA Translation: DAA11220.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S65235

NCBI Reference Sequences

More...
RefSeqi
NP_015108.1, NM_001184030.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YPL216W_mRNA; YPL216W; YPL216W

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
855885

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YPL216W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73572 Genomic DNA Translation: CAA97931.1
BK006949 Genomic DNA Translation: DAA11220.1
PIRiS65235
RefSeqiNP_015108.1, NM_001184030.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi35969, 80 interactors
DIPiDIP-3968N
MINTiQ08964
STRINGi4932.YPL216W

Proteomic databases

PaxDbiQ08964
PRIDEiQ08964

Genome annotation databases

EnsemblFungiiYPL216W_mRNA; YPL216W; YPL216W
GeneIDi855885
KEGGisce:YPL216W

Organism-specific databases

EuPathDBiFungiDB:YPL216W
SGDiS000006137 YPL216W

Phylogenomic databases

InParanoidiQ08964

Enzyme and pathway databases

BioCyciYEAST:G3O-34105-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q08964
RNActiQ08964 protein

Family and domain databases

InterProiView protein in InterPro
IPR018501 DDT_dom
IPR028941 WHIM2_dom
IPR013136 WSTF_Acf1_Cbp146
PfamiView protein in Pfam
PF02791 DDT, 1 hit
PF10537 WAC_Acf1_DNA_bd, 1 hit
PF15613 WSD, 1 hit
SMARTiView protein in SMART
SM00571 DDT, 1 hit
PROSITEiView protein in PROSITE
PS50827 DDT, 1 hit
PS51136 WAC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYP216_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q08964
Secondary accession number(s): D6W3F4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 1, 1996
Last modified: December 11, 2019
This is version 115 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names
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