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UniProtKB - Q08773 (ISW2_YEAST)

Entry version 183 (25 May 2022)
Sequence version 1 (01 Nov 1996)
Previous versions | rss
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Protein

ISWI chromatin-remodeling complex ATPase ISW2

Gene

ISW2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalytic component of the ISW2 complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW2 complex is involved in coordinating transcriptional repression and in inheritance of telomeric silencing. It is involved in repression of MAT a-specific genes, INO1, and early meiotic genes during mitotic growth dependent upon transcription factor UME6 and in a parallel pathway to the RPD3-SIN3 histone deacetylase complex.

7 Publications

Miscellaneous

Present with 1520 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi209 – 216ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, DNA-binding, Helicase, Hydrolase, Repressor
Biological processTranscription, Transcription regulation
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ISWI chromatin-remodeling complex ATPase ISW2 (EC:3.6.4.-)
Alternative name(s):
Imitation switch protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ISW2
Ordered Locus Names:YOR304W
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XV

Organism-specific databases

Saccharomyces Genome Database

More...SGDi		S000005831, ISW2

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		FungiDB:YOR304W

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi215K → A: Abolishes ATPase activity. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002404531 – 1120ISWI chromatin-remodeling complex ATPase ISW2Add BLAST1120

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei17PhosphoserineCombined sources1
Modified residuei19PhosphoserineCombined sources1
Modified residuei831PhosphoserineCombined sources1
Modified residuei1079PhosphothreonineCombined sources1
Modified residuei1082PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q08773

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q08773

PRoteomics IDEntifications database

More...PRIDEi		Q08773

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q08773

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the ISW2 complex, which at least consists of ISW2, ITC1, DLS1 and DPB4. May form a stable subcomplex with ITC1.

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		34692, 343 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-728, ISW2 chromatin remodeling complex
CPX-734, ISW2 chromatin remodeling complex variant 2

Database of interacting proteins

More...DIPi		DIP-6603N

Protein interaction database and analysis system

More...IntActi		Q08773, 40 interactors

Molecular INTeraction database

More...MINTi		Q08773

STRING: functional protein association networks

More...STRINGi		4932.YOR304W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q08773, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q08773

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q08773

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini196 – 361Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST166
Domaini494 – 645Helicase C-terminalPROSITE-ProRule annotationAdd BLAST152
Domaini886 – 938SANTPROSITE-ProRule annotationAdd BLAST53

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 58DisorderedSequence analysisAdd BLAST58
Regioni129 – 153DisorderedSequence analysisAdd BLAST25
Regioni764 – 783DisorderedSequence analysisAdd BLAST20
Regioni828 – 853DisorderedSequence analysisAdd BLAST26
Regioni1062 – 1120DisorderedSequence analysisAdd BLAST59

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi312 – 315DEAH box4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi17 – 41Polar residuesSequence analysisAdd BLAST25
Compositional biasi43 – 58Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi837 – 853Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi1076 – 1104Polar residuesSequence analysisAdd BLAST29
Compositional biasi1105 – 1120Basic and acidic residuesSequence analysisAdd BLAST16

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0385, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000176603

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000315_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q08773

Identification of Orthologs from Complete Genome Data

More...OMAi		IHDWQFF

Family and domain databases

Conserved Domains Database

More...CDDi		cd17997, DEXHc_SMARCA1_SMARCA5, 1 hit
cd00167, SANT, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1040.30, 1 hit
3.40.50.10810, 1 hit
3.40.50.300, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR009057, Homeobox-like_sf
IPR044754, Isw1/2_DEXHc
IPR015194, ISWI_HAND-dom
IPR036306, ISWI_HAND-dom_sf
IPR027417, P-loop_NTPase
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR015195, SLIDE
IPR038718, SNF2-like_sf
IPR000330, SNF2_N

Pfam protein domain database

More...Pfami		View protein in Pfam
PF09110, HAND, 1 hit
PF00271, Helicase_C, 1 hit
PF09111, SLIDE, 1 hit
PF00176, SNF2-rel_dom, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00487, DEXDc, 1 hit
SM00490, HELICc, 1 hit
SM00717, SANT, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF101224, SSF101224, 1 hit
SSF46689, SSF46689, 2 hits
SSF52540, SSF52540, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51192, HELICASE_ATP_BIND_1, 1 hit
PS51194, HELICASE_CTER, 1 hit
PS51293, SANT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q08773-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTQQEEQRS DTKNSKSESP SEVLVDTLDS KSNGSSDDDN IGQSEELSDK 
        60         70         80         90        100
EIYTVEDRPP EYWAQRKKKF VLDVDPKYAK QKDKSDTYKR FKYLLGVTDL 
       110        120        130        140        150
FRHFIGIKAK HDKNIQKLLK QLDSDANKLS KSHSTVSSSS RHHRKTEKEE 
       160        170        180        190        200
DAELMADEEE EIVDTYQEDI FVSESPSFVK SGKLRDYQVQ GLNWLISLHE 
       210        220        230        240        250
NKLSGILADE MGLGKTLQTI SFLGYLRYVK QIEGPFLIIV PKSTLDNWRR 
       260        270        280        290        300
EFLKWTPNVN VLVLHGDKDT RADIVRNIIL EARFDVLITS YEMVIREKNA 
       310        320        330        340        350
LKRLAWQYIV IDEAHRIKNE QSALSQIIRL FYSKNRLLIT GTPLQNNLHE 
       360        370        380        390        400
LWALLNFLLP DIFGDSELFD EWFEQNNSEQ DQEIVIQQLH SVLNPFLLRR 
       410        420        430        440        450
VKADVEKSLL PKIETNVYVG MTDMQIQWYK SLLEKDIDAV NGAVGKREGK 
       460        470        480        490        500
TRLLNIVMQL RKCCNHPYLF EGAEPGPPYT TDEHLIFNSG KMIILDKLLK 
       510        520        530        540        550
RLKEKGSRVL IFSQMSRLLD ILEDYCYFRD FEYCRIDGST SHEERIEAID 
       560        570        580        590        600
EYNKPNSEKF VFLLTTRAGG LGINLVTADT VILFDSDWNP QADLQAMDRA 
       610        620        630        640        650
HRIGQKKQVH VYRFVTENAI EEKVIERAAQ KLRLDQLVIQ QGTGKKTASL 
       660        670        680        690        700
GNSKDDLLDM IQFGAKNMFE KKASKVTVDA DIDDILKKGE QKTQELNAKY 
       710        720        730        740        750
QSLGLDDLQK FNGIENQSAY EWNGKSFQKK SNDKVVEWIN PSRRERRREQ 
       760        770        780        790        800
TTYSVDDYYK EIIGGGSKSA SKQTPQPKAP RAPKVIHGQD FQFFPKELDA 
       810        820        830        840        850
LQEKEQLYFK KKVNYKVTSY DITGDIRNEG SDAEEEEGEY KNAANTEGHK 
       860        870        880        890        900
GHEELKRRIE EEQEKINSAP DFTQEDELRK QELISKAFTN WNKRDFMAFI 
       910        920        930        940        950
NACAKYGRDD MENIKKSIDS KTPEEVEVYA KIFWERLKEI NGWEKYLHNV 
       960        970        980        990       1000
ELGEKKNEKL KFQETLLRQK IEQCKHPLHE LIIQYPPNNA RRTYNTLEDK 
      1010       1020       1030       1040       1050
FLLLAVNKYG LRADKLYEKL KQEIMMSDLF TFDWFIKTRT VHELSKRVHT 
      1060       1070       1080       1090       1100
LLTLIVREYE QPDANKKKRS RTSATREDTP LSQNESTRAS TVPNLPTTMV 
      1110       1120
TNQKDTNDHV DKRTKIDQEA
Length:1,120
Mass (Da):130,327
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF71007D7B25C9348
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Z75212 Genomic DNA Translation: CAA99622.1
BK006948 Genomic DNA Translation: DAA11069.1

Protein sequence database of the Protein Information Resource

More...PIRi		S67208

NCBI Reference Sequences

More...RefSeqi		NP_014948.1, NM_001183724.1

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		YOR304W_mRNA; YOR304W; YOR304W

Database of genes from NCBI RefSeq genomes

More...GeneIDi		854480

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		sce:YOR304W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75212 Genomic DNA Translation: CAA99622.1
BK006948 Genomic DNA Translation: DAA11069.1
PIRiS67208
RefSeqiNP_014948.1, NM_001183724.1

3D structure databases

AlphaFoldDBiQ08773
SMRiQ08773
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi34692, 343 interactors
ComplexPortaliCPX-728, ISW2 chromatin remodeling complex
CPX-734, ISW2 chromatin remodeling complex variant 2
DIPiDIP-6603N
IntActiQ08773, 40 interactors
MINTiQ08773
STRINGi4932.YOR304W

PTM databases

iPTMnetiQ08773

Proteomic databases

MaxQBiQ08773
PaxDbiQ08773
PRIDEiQ08773

Genome annotation databases

EnsemblFungiiYOR304W_mRNA; YOR304W; YOR304W
GeneIDi854480
KEGGisce:YOR304W

Organism-specific databases

SGDiS000005831, ISW2
VEuPathDBiFungiDB:YOR304W

Phylogenomic databases

eggNOGiKOG0385, Eukaryota
GeneTreeiENSGT00940000176603
HOGENOMiCLU_000315_0_0_1
InParanoidiQ08773
OMAiIHDWQFF

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q08773
RNActiQ08773, protein

Family and domain databases

CDDicd17997, DEXHc_SMARCA1_SMARCA5, 1 hit
cd00167, SANT, 1 hit
Gene3Di1.10.1040.30, 1 hit
3.40.50.10810, 1 hit
3.40.50.300, 1 hit
InterProiView protein in InterPro
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR009057, Homeobox-like_sf
IPR044754, Isw1/2_DEXHc
IPR015194, ISWI_HAND-dom
IPR036306, ISWI_HAND-dom_sf
IPR027417, P-loop_NTPase
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR015195, SLIDE
IPR038718, SNF2-like_sf
IPR000330, SNF2_N
PfamiView protein in Pfam
PF09110, HAND, 1 hit
PF00271, Helicase_C, 1 hit
PF09111, SLIDE, 1 hit
PF00176, SNF2-rel_dom, 1 hit
SMARTiView protein in SMART
SM00487, DEXDc, 1 hit
SM00490, HELICc, 1 hit
SM00717, SANT, 2 hits
SUPFAMiSSF101224, SSF101224, 1 hit
SSF46689, SSF46689, 2 hits
SSF52540, SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS51192, HELICASE_ATP_BIND_1, 1 hit
PS51194, HELICASE_CTER, 1 hit
PS51293, SANT, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiISW2_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q08773
Secondary accession number(s): D6W303
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 1, 1996
Last modified: May 25, 2022
This is version 183 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families
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