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UniProtKB - Q08512 (MCES_SWPVK)
Protein
mRNA-capping enzyme small subunit
Gene
N/A
Organism
Swinepox virus (strain Kasza) (SWPV)
Status
Functioni
Catalyzes the last reaction in the mRNA cap formation pathway.
Catalytic activityi
- a 5'-end (5'-triphosphoguanosine)-(ribonucleoside) in mRNA + S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteineEC:2.1.1.56
GO - Molecular functioni
- mRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-EC
Keywordsi
Molecular function | Methyltransferase, Transferase |
Biological process | mRNA capping, mRNA processing |
Ligand | S-adenosyl-L-methionine |
Names & Taxonomyi
Protein namesi | Recommended name: mRNA-capping enzyme small subunitAlternative name(s): mRNA (guanine-N(7))-methyltransferase (EC:2.1.1.56) mRNA cap methyltransferase |
Organismi | Swinepox virus (strain Kasza) (SWPV) |
Taxonomic identifieri | 10277 [NCBI] |
Taxonomic lineagei | Viruses › Varidnaviria › Bamfordvirae › Nucleocytoviricota › Pokkesviricetes › Chitovirales › Poxviridae › Chordopoxvirinae › Suipoxvirus › |
Virus hosti | Sus scrofa (Pig) [TaxID: 9823] |
Subcellular locationi
- Virion Curated Note: All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.
Keywords - Cellular componenti
VirionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000210140 | 1 – 287 | mRNA-capping enzyme small subunitAdd BLAST | 287 |
Interactioni
Subunit structurei
Heterodimer of a large and a small subunit.
Family & Domainsi
Family and domain databases
Gene3Di | 3.40.50.11680, 1 hit |
InterProi | View protein in InterPro IPR005009, Poxvirus_mRNA-cap_ssu IPR043096, Poxvirus_mRNA-cap_ssu_sf |
Pfami | View protein in Pfam PF03341, Pox_mRNA-cap, 1 hit |
i Sequence
Sequence statusi: Complete.
Q08512-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDKITRNIRE GIHILLPFYE NLPDISLSLG KSPLPSLEYG TNYFLQLSRV
60 70 80 90 100
NDLNRLPTDM LSLFTHDIML PETDMEKVYD ILNIKSVKSY GKSIKADAVV
110 120 130 140 150
ADLSARNRLF KKDRELIKSN NYLTDNNLYI SDYKMLTFEV FRPLFDLSSE
160 170 180 190 200
KYCIVKLPTL FGKCVIDTIR VYCSLFKSVR LFKCASDSWL KDSAIMVASD
210 220 230 240 250
IYKKNIDIFM SHIRSVLKSQ YWKDSNNVQF SILKESVDKE FINKFLEFST
260 270 280
SVYESLYYVH SLLYSSMISD NKSIENEYQK KLTKLLL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L22012 Unassigned DNA Translation: AAA16177.1 |
RefSeqi | NP_570246.1, NC_003389.1 |
Genome annotation databases
GeneIDi | 932372 |
KEGGi | vg:932372 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L22012 Unassigned DNA Translation: AAA16177.1 |
RefSeqi | NP_570246.1, NC_003389.1 |
3D structure databases
SMRi | Q08512 |
ModBasei | Search... |
Genome annotation databases
GeneIDi | 932372 |
KEGGi | vg:932372 |
Family and domain databases
Gene3Di | 3.40.50.11680, 1 hit |
InterProi | View protein in InterPro IPR005009, Poxvirus_mRNA-cap_ssu IPR043096, Poxvirus_mRNA-cap_ssu_sf |
Pfami | View protein in Pfam PF03341, Pox_mRNA-cap, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MCES_SWPVK | |
Accessioni | Q08512Primary (citable) accession number: Q08512 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | October 1, 1994 | |
Last modified: | September 29, 2021 | |
This is version 71 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |