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Protein

UvrABC system protein C

Gene

uvrC

Organism
Shewanella frigidimarina (strain NCIMB 400)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciSFRI318167:G1G77-2739-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Sfri_2648
OrganismiShewanella frigidimarina (strain NCIMB 400)
Taxonomic identifieri318167 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000000684 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002649461 – 610UvrABC system protein CAdd BLAST610

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi318167.Sfri_2648

Structurei

3D structure databases

ProteinModelPortaliQ07ZS6
SMRiQ07ZS6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 94GIY-YIGUniRule annotationAdd BLAST79
Domaini203 – 238UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII Bacteria
COG0322 LUCA
HOGENOMiHOG000279961
KOiK03703
OMAiLFPIRQC
OrthoDBiPOG091H01BS

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR003583 Hlx-hairpin-Hlx_DNA-bd_motif
IPR010994 RuvA_2-like
IPR001943 UVR_dom
IPR036876 UVR_dom_sf
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF02151 UVR, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SM00278 HhH1, 2 hits
SUPFAMiSSF46600 SSF46600, 1 hit
SSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50151 UVR, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

Q07ZS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSGFNAKSF LKNVTSAPGV YRMYDKHQQV IYVGKAKDLK KRLSSYFRVN
60 70 80 90 100
IANVKTQALV SHIDHIDVTV THSETDALLL ENDYIKQYMP KYNVLLRDDK
110 120 130 140 150
SYPYILLSGH KHPRLAYHRG PKREKGHYFG PYPNGGAVRE SLHLIQKLFP
160 170 180 190 200
IRQCDDLYYK SRSRPCLQYQ LDRCSAPCVG IVSDDEYSEQ VKLAGLFLRG
210 220 230 240 250
KDKQVISQLV AKMETAAIDM EYERAAQYRD QITALRRVAE QQEVSNHKGD
260 270 280 290 300
MDVIGVDYAS GIACFHLLFI RDGKIFGSRS YYPSVPAETE IEEVLSSFLG
310 320 330 340 350
QFYLNADIQR TIPKEVILSH HFDGITELQA SIEHALDKKF ELKTQVRGDR
360 370 380 390 400
ANFLRLAMTN ASNAVATKLS HKNTVEQRFQ LLEEALELNE PIKRMECFDI
410 420 430 440 450
SHTMGESTVA SCVVFNREGP HKADYRRYNI TGITGGDDYA AMEQAISRRF
460 470 480 490 500
DKIDNNGKVP DLVFIDGGIG QLRVAQTIVD EKCVNIDHPP LLICVTKGEG
510 520 530 540 550
RKAGLETFTV GGSEQTFEVA SDSPAFHLML HIRDESHRFA ITGHRNKRQK
560 570 580 590 600
TRNTSTLESI AGVGPKRRKA LLQHLGGIQE VKGASVAELT KVPGISLEMA
610
QTIHDALRGG
Length:610
Mass (Da):68,647
Last modified:October 31, 2006 - v1
Checksum:i70454927AE69FFA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000447 Genomic DNA Translation: ABI72489.1
RefSeqiWP_011638097.1, NC_008345.1

Genome annotation databases

EnsemblBacteriaiABI72489; ABI72489; Sfri_2648
KEGGisfr:Sfri_2648

Similar proteinsi

Entry informationi

Entry nameiUVRC_SHEFN
AccessioniPrimary (citable) accession number: Q07ZS6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 31, 2006
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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