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Entry version 160 (02 Jun 2021)
Sequence version 1 (01 Nov 1996)
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Protein

E3 ubiquitin-protein ligase UBR2

Gene

UBR2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

E3 ubiquitin-protein ligase which probably functions outside the N-end rule pathway, since it lacks the residues essential for the degradation of N-end rule substrates. Mediates RPN4 ubiquitination and subsequent degradation.

2 Publications

Miscellaneous

Present with 49 molecules/cell in log phase SD medium.1 Publication
Deletion produces no detectable phenotype.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine. EC:2.3.2.27

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri96 – 172UBR-typePROSITE-ProRule annotationAdd BLAST77
Zinc fingeri1241 – 1362RING-type; atypicalAdd BLAST122

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SCE-983168, Antigen processing: Ubiquitination & Proteasome degradation

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
E3 ubiquitin-protein ligase UBR2 (EC:2.3.2.27)
Alternative name(s):
RING-type E3 ubiquitin transferase UBR2
Ubiquitin-protein ligase E3 component N-recognin-1 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:UBR2
Ordered Locus Names:YLR024C
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XII

Organism-specific databases

Saccharomyces Genome Database

More...
SGDi
S000004014, UBR2

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:YLR024C

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000561421 – 1872E3 ubiquitin-protein ligase UBR2Add BLAST1872

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki709Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1218PhosphoserineCombined sources1
Modified residuei1222PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q07963

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q07963

PRoteomics IDEntifications database

More...
PRIDEi
Q07963

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q07963

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with MUB1, RPN4 and UBC2.

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
31298, 438 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-2935, RAD6-UBR2 ubiquitin ligase complex
CPX-2937, MUB1-RAD6-UBR2 ubiquitin ligase complex

Database of interacting proteins

More...
DIPi
DIP-6593N

Protein interaction database and analysis system

More...
IntActi
Q07963, 6 interactors

Molecular INTeraction database

More...
MINTi
Q07963

STRING: functional protein association networks

More...
STRINGi
4932.YLR024C

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q07963, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q07963

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1134 – 1240Interaction with UBC2Add BLAST107
Regioni1203 – 1227DisorderedSequence analysisAdd BLAST25

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The RING-H2 zinc finger is an atypical RING finger with a His ligand in place of the fourth Cys of the classical motif.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UBR1 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri96 – 172UBR-typePROSITE-ProRule annotationAdd BLAST77
Zinc fingeri1241 – 1362RING-type; atypicalAdd BLAST122

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1140, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183075

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004097_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q07963

Identification of Orthologs from Complete Genome Data

More...
OMAi
PLYEICE

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR044046, E3_ligase_UBR-like_C
IPR039164, UBR1-like
IPR003126, Znf_UBR

The PANTHER Classification System

More...
PANTHERi
PTHR21497, PTHR21497, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18995, PRT6_C, 1 hit
PF02207, zf-UBR, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00396, ZnF_UBR1, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51157, ZF_UBR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q07963-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEDSDLSITN IRDFLTELPK LAKCEYSETT SYLLWKTLNL RLKHSDNDIN
60 70 80 90 100
WRSLVSILNS EAWENEKYRD ILNGRKWRTL EFENDHHSVG NMHIGTACTR
110 120 130 140 150
LCFPSETIYY CFTCSTNPLY EICELCFDKE KHVNHSYVAK VVMRPEGRIC
160 170 180 190 200
HCGDPFAFND PSDAFKCKNE LNNIPISNDN SNVTDDENVI SLLNYVLDFL
210 220 230 240 250
IDVTVSYKEE AEAHSSERKA SSLMHPNQNS ITDDIMEKHE CEPLVNDENF
260 270 280 290 300
VFFDNNWSNT RKEAHMEWAI QIEEEECNVH YMDLASTITR ILNTPVEYAI
310 320 330 340 350
SITKALEDSH DVVTVLQSEN FFEIDQIAKE FQKENIVVHV RKADDIFKRK
360 370 380 390 400
LTDDLTDWLY SLCFKAATSL QNKYALRISM LDVWYSHFSK MRVSPTNTNP
410 420 430 440 450
DFSKINLLGG FLISNEDSDE SWFKPWSLEN IEDERISKIL TNYNERLIRA
460 470 480 490 500
HSPNTVSHFY NFYGSRFQYI IINSINILSK KSKFKMLKIM ASLFSLRDES
510 520 530 540 550
RKFLAAQYID VYLSVLYDAV ASDAKECQVT LMSILGQYTF QDPSIANMTI
560 570 580 590 600
SSGFIERTIR FAFTLMAFNP EDLMSYLPIS LYNGFKLPTE TIRNRRTIIC
610 620 630 640 650
FKDLCTIMSA NTVPEELLSN EAIFNAIIES FSEFSNVLPL KRETKEHVEV
660 670 680 690 700
ENFDFSAFYF FFSSILIMTD GYTRSISLVK DAAFRKQIVL KLLDVAQTRE
710 720 730 740 750
FESLTNSRKA ISPDNASTNE NDSNKATLST VRETICNYVA ETINFQVGVN
760 770 780 790 800
TQYFFNPMSY LFKFVIQWSQ CGRYEPIPAS LTNYINLFEV FQDKQKALYI
810 820 830 840 850
SESALSTLVL IGQINVGFWV RNGTPITHQA RMYTKYSMRE FTYISDIFNV
860 870 880 890 900
QFSMAMCNPD ELMVTYLSRW GLKHWANGVP MYDYPDTETT VAVVNECILL
910 920 930 940 950
LIQLLTEVRS LVMKSSKEGF ERTFKSEIIH ALCFDTCSYA QIVNCIPEHI
960 970 980 990 1000
TKHPSFDIYL EKYANYTSPV SLTDNGIFVL KEKYKDEIDP YYIGLSSSRR
1010 1020 1030 1040 1050
YDVEKNIRLN MANLKKMKYE DTFVPAKKVK DLLKNTLFSG LYSISSVNTF
1060 1070 1080 1090 1100
GLFLKNTLDH IIKYDYDNLL PRVVHLIHLC VVNNLNEFMG ILWHEYAIVD
1110 1120 1130 1140 1150
TEFCHYHSIG SILYYCLLKD NFSESHGKIR EIFRYLMETA PHVNVNSYLR
1160 1170 1180 1190 1200
EQTTSYTPGI LWPTKEDKSH KDKEFERKKH LARLRKKKLM KKLAQQQMKF
1210 1220 1230 1240 1250
MENNSVDTSD ISTPRTTSPS LSPTRINAEN SSNTINSCCD DDCVFCKMPK
1260 1270 1280 1290 1300
DDDVFVYFSY QERNICDHGI DFTNPTDVNR INSLFSGKQT KDSAIQENPQ
1310 1320 1330 1340 1350
DDDGTRLKFT SCEPVLRACG HGSHTKCLSG HMKSIRGIQN QTTKNIPLSY
1360 1370 1380 1390 1400
GSGLIYCPVC NSLSNSFLPK TNDIDKRTSS QFFMCIEKRS EAEENLDPMS
1410 1420 1430 1440 1450
SICIKAAMIL GDLQGKKVTT IEDAYKVVNS VFINTISNTE LRLRSHKKEG
1460 1470 1480 1490 1500
KIVNMERISS QCILTLHLVC ELKSFIYKKF VNSKTFSSEI SRKIWNWNEF
1510 1520 1530 1540 1550
LIKGNNVNLL LYMSQNFDNI DGGKTPQPPN LCIYEMFKRR FHQLLLLLAR
1560 1570 1580 1590 1600
DMMRVNFYKD CRNKIKISSN GSEEPSTSFS YLFNTFKKYV DLFKPDDVRF
1610 1620 1630 1640 1650
DFTSLEKIKD FICSLLLESL SIFCRRTFLL FNIQYDDDGD GDNNNNRSNN
1660 1670 1680 1690 1700
FMDVKQREIE LIFRYFKLPN LTHFLKDFFY NELTQNIERY NDGNDNLRIQ
1710 1720 1730 1740 1750
QVIYDMVQNI NTRAYPSPEH IQLIELPLNL SKFSLDNDEI SNKCDKYEIA
1760 1770 1780 1790 1800
VCLLCGQKCH IQKSIALQGY LQGECTDHMR NGCEITSAYG VFLMTGTNAI
1810 1820 1830 1840 1850
YLSYGKRGTF YAAPYLSKYG ETNEDYKFGT PVYLNRARYA NLANEIVFGN
1860 1870
MIPHIVFRLT DGSADLGGWE TM
Length:1,872
Mass (Da):216,778
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1F60CC41EB88752F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z73196 Genomic DNA Translation: CAA97547.1
BK006945 Genomic DNA Translation: DAA09342.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S64851

NCBI Reference Sequences

More...
RefSeqi
NP_013124.1, NM_001181911.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YLR024C_mRNA; YLR024C; YLR024C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
850711

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YLR024C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73196 Genomic DNA Translation: CAA97547.1
BK006945 Genomic DNA Translation: DAA09342.1
PIRiS64851
RefSeqiNP_013124.1, NM_001181911.2

3D structure databases

SMRiQ07963
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi31298, 438 interactors
ComplexPortaliCPX-2935, RAD6-UBR2 ubiquitin ligase complex
CPX-2937, MUB1-RAD6-UBR2 ubiquitin ligase complex
DIPiDIP-6593N
IntActiQ07963, 6 interactors
MINTiQ07963
STRINGi4932.YLR024C

PTM databases

iPTMnetiQ07963

Proteomic databases

MaxQBiQ07963
PaxDbiQ07963
PRIDEiQ07963

Genome annotation databases

EnsemblFungiiYLR024C_mRNA; YLR024C; YLR024C
GeneIDi850711
KEGGisce:YLR024C

Organism-specific databases

SGDiS000004014, UBR2
VEuPathDBiFungiDB:YLR024C

Phylogenomic databases

eggNOGiKOG1140, Eukaryota
GeneTreeiENSGT00950000183075
HOGENOMiCLU_004097_0_0_1
InParanoidiQ07963
OMAiPLYEICE

Enzyme and pathway databases

UniPathwayiUPA00143
ReactomeiR-SCE-983168, Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q07963
RNActiQ07963, protein

Family and domain databases

InterProiView protein in InterPro
IPR044046, E3_ligase_UBR-like_C
IPR039164, UBR1-like
IPR003126, Znf_UBR
PANTHERiPTHR21497, PTHR21497, 1 hit
PfamiView protein in Pfam
PF18995, PRT6_C, 1 hit
PF02207, zf-UBR, 1 hit
SMARTiView protein in SMART
SM00396, ZnF_UBR1, 1 hit
PROSITEiView protein in PROSITE
PS51157, ZF_UBR, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUBR2_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q07963
Secondary accession number(s): D6VY26
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: November 1, 1996
Last modified: June 2, 2021
This is version 160 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  4. SIMILARITY comments
    Index of protein domains and families
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