UniProtKB - Q07955 (SRSF1_HUMAN)
Serine/arginine-rich splicing factor 1
SRSF1
Functioni
GO - Molecular functioni
- DNA topoisomerase binding Source: CAFA
- mRNA binding Source: MGI
- RNA binding Source: UniProtKB
GO - Biological processi
- alternative mRNA splicing, via spliceosome Source: GO_Central
- mRNA 3'-end processing Source: Reactome
- mRNA 5'-splice site recognition Source: UniProtKB
- mRNA cis splicing, via spliceosome Source: GO_Central
- mRNA export from nucleus Source: Reactome
- mRNA processing Source: ProtInc
- mRNA splice site selection Source: ProtInc
- mRNA splicing, via spliceosome Source: Reactome
- regulation of alternative mRNA splicing, via spliceosome Source: GO_Central
- RNA export from nucleus Source: Reactome
Keywordsi
Molecular function | RNA-binding |
Biological process | mRNA processing, mRNA splicing, mRNA transport, Transport |
Enzyme and pathway databases
PathwayCommonsi | Q07955 |
Reactomei | R-HSA-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-72163, mRNA Splicing - Major Pathway R-HSA-72165, mRNA Splicing - Minor Pathway R-HSA-72187, mRNA 3'-end processing R-HSA-73856, RNA Polymerase II Transcription Termination |
SIGNORi | Q07955 |
Names & Taxonomyi
Protein namesi | Recommended name: Serine/arginine-rich splicing factor 1Alternative name(s): Alternative-splicing factor 1 Short name: ASF-1 Splicing factor, arginine/serine-rich 1 pre-mRNA-splicing factor SF2, P33 subunit |
Gene namesi | Name:SRSF1 Synonyms:ASF, SF2, SF2P33, SFRS1 ORF Names:OK/SW-cl.3 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000136450.12 |
HGNCi | HGNC:10780, SRSF1 |
MIMi | 600812, gene |
neXtProti | NX_Q07955 |
Subcellular locationi
Nucleus
- Nucleus speckle 4 Publications
Other locations
- Cytoplasm 4 Publications
Note: In nuclear speckles. Shuttles between the nucleus and the cytoplasm (PubMed:12215544, PubMed:20308322, PubMed:9420331, PubMed:24449914). Nuclear import is mediated via interaction with TNPO3 (PubMed:24449914).4 Publications
Nucleus
- catalytic step 2 spliceosome Source: UniProtKB
- nuclear speck Source: MGI
- nucleoplasm Source: UniProtKB
- nucleus Source: UniProtKB
Other locations
- cytoplasm Source: UniProtKB
Keywords - Cellular componenti
Cytoplasm, Nucleus, SpliceosomePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 58 – 59 | FV → SR in FV1; loss of ability to activate splicing. Slight reduction in splice site switching activity and no effect on RNA-binding. 1 Publication | 2 | |
Mutagenesisi | 93 | R → A: Predominantly localizes to cytoplasm and fails to modulate splicing of endogenous pre-mRNAs; when associated with Ala-97 and Ala-109. 1 Publication | 1 | |
Mutagenesisi | 97 | R → A: Predominantly localizes to cytoplasm and fails to modulate splicing of endogenous pre-mRNAs; when associated with Ala-93 and Ala-109. 1 Publication | 1 | |
Mutagenesisi | 109 | R → A: Predominantly localizes to cytoplasm and fails to modulate splicing of endogenous pre-mRNAs; when associated with Ala-93 and Ala-97. 1 Publication | 1 | |
Mutagenesisi | 162 – 163 | FV → SR in FV2; loss of ability to activate splicing. Great reduction in splice site switching activity and RNA-binding. 1 Publication | 2 | |
Mutagenesisi | 162 | F → A in AV; loss of ability to activate splicing. Great reduction in splice site switching activity and no effect on RNA-binding. 1 Publication | 1 | |
Mutagenesisi | 162 | F → D: Reduced nucleocytoplasmic shuttling; when associated with D-190. 1 Publication | 1 | |
Mutagenesisi | 180 | F → D: Reduced nucleocytoplasmic shuttling; when associated with D-162. 1 Publication | 1 | |
Mutagenesisi | 182 – 248 | Missing in MR-B; strongly inhibits splicing. 1 PublicationAdd BLAST | 67 | |
Mutagenesisi | 182 – 199 | Missing in MR-E; loss of ability to activate splicing. 1 PublicationAdd BLAST | 18 | |
Mutagenesisi | 192 – 248 | Missing in MR-A; loss of ability to activate splicing. 1 PublicationAdd BLAST | 57 | |
Mutagenesisi | 192 – 199 | Missing in MR-D; loss of ability to activate splicing. 1 Publication | 8 | |
Mutagenesisi | 199 – 224 | Missing in RS-A; loss of ability to activate splicing but retains splice site switching. 1 PublicationAdd BLAST | 26 | |
Mutagenesisi | 215 – 248 | Missing in RS-C; loss of ability to activate splicing but retains splice site switching. 1 PublicationAdd BLAST | 34 | |
Mutagenesisi | 226 – 248 | Missing in RS-B; retains both splice activation and splice site switching activity. 1 PublicationAdd BLAST | 23 |
Organism-specific databases
DisGeNETi | 6426 |
OpenTargetsi | ENSG00000136450 |
PharmGKBi | PA35696 |
Miscellaneous databases
Pharosi | Q07955, Tbio |
Chemistry databases
ChEMBLi | CHEMBL4295805 |
DrugBanki | DB09130, Copper |
Polymorphism and mutation databases
BioMutai | SRSF1 |
DMDMi | 730773 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedCombined sources | |||
ChainiPRO_0000081911 | 2 – 248 | Serine/arginine-rich splicing factor 1Add BLAST | 247 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylserineCombined sources | 1 | |
Modified residuei | 2 | PhosphoserineCombined sources | 1 | |
Cross-linki | 30 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 38 | N6-acetyllysine; alternateCombined sources | 1 | |
Cross-linki | 38 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources | ||
Modified residuei | 93 | Asymmetric dimethylarginine; alternate1 Publication | 1 | |
Modified residuei | 93 | Omega-N-methylarginine; alternateCombined sources | 1 | |
Modified residuei | 97 | Asymmetric dimethylarginine; alternate1 Publication | 1 | |
Modified residuei | 97 | Omega-N-methylarginine; alternateCombined sources | 1 | |
Modified residuei | 109 | Asymmetric dimethylarginine; alternate1 Publication | 1 | |
Modified residuei | 109 | Omega-N-methylarginine; alternateCombined sources | 1 | |
Modified residuei | 111 | Omega-N-methylarginineCombined sources | 1 | |
Modified residuei | 133 | PhosphoserineCombined sources | 1 | |
Modified residuei | 179 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 199 | PhosphoserineCombined sources | 1 | |
Modified residuei | 201 | PhosphoserineCombined sources1 Publication | 1 | |
Modified residuei | 202 | PhosphotyrosineCombined sources | 1 | |
Modified residuei | 205 | PhosphoserineCombined sources | 1 | |
Modified residuei | 207 | Phosphoserine1 Publication | 1 | |
Modified residuei | 209 | Phosphoserine1 Publication | 1 | |
Modified residuei | 231 | PhosphoserineCombined sources | 1 | |
Modified residuei | 234 | PhosphoserineCombined sources | 1 | |
Modified residuei | 238 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Keywords - PTMi
Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q07955 |
jPOSTi | Q07955 |
MassIVEi | Q07955 |
MaxQBi | Q07955 |
PaxDbi | Q07955 |
PeptideAtlasi | Q07955 |
PRIDEi | Q07955 |
ProteomicsDBi | 58560 [Q07955-1] 58561 [Q07955-2] 58562 [Q07955-3] |
TopDownProteomicsi | Q07955-1 [Q07955-1] Q07955-2 [Q07955-2] Q07955-3 [Q07955-3] |
PTM databases
iPTMneti | Q07955 |
PhosphoSitePlusi | Q07955 |
SwissPalmi | Q07955 |
Expressioni
Gene expression databases
Bgeei | ENSG00000136450, Expressed in oviduct epithelium and 252 other tissues |
ExpressionAtlasi | Q07955, baseline and differential |
Genevisiblei | Q07955, HS |
Organism-specific databases
HPAi | ENSG00000136450, Low tissue specificity |
Interactioni
Subunit structurei
Consists of two polypeptides of p32 and p33. In vitro, self-associates and binds SRSF2, SNRNP70 and U2AF1 but not U2AF2. Binds SREK1/SFRS12.
Interacts with SAFB/SAFB1.
Interacts with PSIP1/LEDGF.
Interacts with SRPK1. Identified in the spliceosome C complex.
Interacts with RSRC1 (via Arg/Ser-rich domain).
Interacts with ZRSR2/U2AF1-RS2.
Interacts with CCDC55 (via C-terminus).
Interacts with SRPK1 and a sliding docking interaction is essential for its sequential and processive phosphorylation by SRPK1.
Interacts with NXF1.
Interacts with CCNL1, CCNL2 and CDK11B (PubMed:18216018).
Interacts with RRP1B (PubMed:23604122).
Interacts (when phosphorylated in its RS domain) with TNPO3; promoting nuclear import (PubMed:24449914).
14 PublicationsBinary interactionsi
Hide detailsQ07955
GO - Molecular functioni
- DNA topoisomerase binding Source: CAFA
Protein-protein interaction databases
BioGRIDi | 112324, 229 interactors |
CORUMi | Q07955 |
DIPi | DIP-2155N |
IntActi | Q07955, 97 interactors |
MINTi | Q07955 |
STRINGi | 9606.ENSP00000258962 |
Miscellaneous databases
RNActi | Q07955, protein |
Structurei
Secondary structure
3D structure databases
BMRBi | Q07955 |
SMRi | Q07955 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q07955 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 91 | RRM 1PROSITE-ProRule annotationAdd BLAST | 76 | |
Domaini | 121 – 195 | RRM 2PROSITE-ProRule annotationAdd BLAST | 75 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 198 – 247 | Interaction with SAFB1Add BLAST | 50 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 94 – 113 | Gly-rich (hinge region)Add BLAST | 20 | |
Compositional biasi | 198 – 247 | Arg/Ser-rich (RS domain)Add BLAST | 50 |
Domaini
Sequence similaritiesi
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | KOG0105, Eukaryota |
GeneTreei | ENSGT00940000155585 |
HOGENOMi | CLU_012062_34_5_1 |
InParanoidi | Q07955 |
OrthoDBi | 1321443at2759 |
PhylomeDBi | Q07955 |
TreeFami | TF106261 |
Family and domain databases
CDDi | cd12597, RRM1_SRSF1, 1 hit |
DisProti | DP01641 |
Gene3Di | 3.30.70.330, 2 hits |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom IPR029538, SRSF1 IPR034520, SRSF1_RRM1 |
PANTHERi | PTHR23147:SF44, PTHR23147:SF44, 1 hit |
Pfami | View protein in Pfam PF00076, RRM_1, 2 hits |
SMARTi | View protein in SMART SM00360, RRM, 2 hits |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 2 hits |
s (3+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MSGGGVIRGP AGNNDCRIYV GNLPPDIRTK DIEDVFYKYG AIRDIDLKNR
60 70 80 90 100
RGGPPFAFVE FEDPRDAEDA VYGRDGYDYD GYRLRVEFPR SGRGTGRGGG
110 120 130 140 150
GGGGGGAPRG RYGPPSRRSE NRVVVSGLPP SGSWQDLKDH MREAGDVCYA
160 170 180 190 200
DVYRDGTGVV EFVRKEDMTY AVRKLDNTKF RSHEGETAYI RVKVDGPRSP
210 220 230 240
SYGRSRSRSR SRSRSRSRSN SRSRSYSPRR SRGSPRYSPR HSRSRSRT
The sequence of this isoform differs from the canonical sequence as follows:
185-248: GETAYIRVKV...PRHSRSRSRT → FCLSNREKLP...NCFVQNGLKC
The sequence of this isoform differs from the canonical sequence as follows:
185-201: GETAYIRVKVDGPRSPS → VGYTRILFFDQNWIQWS
202-248: Missing.
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketJ3KTL2 | J3KTL2_HUMAN | Serine/arginine-rich splicing facto... | SRSF1 SFRS1, hCG_1774411 | 253 | Annotation score: | ||
J3KSR8 | J3KSR8_HUMAN | Serine/arginine-rich splicing facto... | SRSF1 | 143 | Annotation score: | ||
J3QQV5 | J3QQV5_HUMAN | Serine/arginine-rich splicing facto... | SRSF1 SFRS1, hCG_1774411 | 65 | Annotation score: | ||
J3KSW7 | J3KSW7_HUMAN | Serine/arginine-rich splicing facto... | SRSF1 | 73 | Annotation score: |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_035488 | 89 | P → S in a breast cancer sample; somatic mutation. 1 Publication | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_005856 | 185 – 248 | GETAY…SRSRT → FCLSNREKLPTSGLKLMGPE VQVMEDLDLEAVVVAEAVAE ATAGVAVTPQGEAEDHHAIL PVIADLALVHKMIGDTFCRT HVVYSFPLFSTIFSFFNSNC FVQNGLKC in isoform ASF-2. 1 PublicationAdd BLAST | 64 | |
Alternative sequenceiVSP_005857 | 185 – 201 | GETAY…PRSPS → VGYTRILFFDQNWIQWS in isoform ASF-3. 1 PublicationAdd BLAST | 17 | |
Alternative sequenceiVSP_005858 | 202 – 248 | Missing in isoform ASF-3. 1 PublicationAdd BLAST | 47 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M72709 mRNA Translation: AAA35565.1 M72709 mRNA Translation: AAA35564.1 M69040 mRNA Translation: AAA03476.1 AB062124 mRNA Translation: BAB93456.1 AK312781 mRNA Translation: BAG35644.1 CH471109 Genomic DNA Translation: EAW94485.1 CH471109 Genomic DNA Translation: EAW94486.1 BC010264 mRNA Translation: AAH10264.1 BC033785 mRNA Translation: AAH33785.1 |
CCDSi | CCDS11600.1 [Q07955-1] CCDS58580.1 [Q07955-3] |
PIRi | A40040 B40040 C40040 |
RefSeqi | NP_001071634.1, NM_001078166.1 [Q07955-3] NP_008855.1, NM_006924.4 [Q07955-1] |
Genome annotation databases
Ensembli | ENST00000258962; ENSP00000258962; ENSG00000136450 [Q07955-1] ENST00000581979; ENSP00000463223; ENSG00000136450 [Q07955-3] ENST00000582730; ENSP00000462215; ENSG00000136450 [Q07955-3] |
GeneIDi | 6426 |
KEGGi | hsa:6426 |
UCSCi | uc002ivi.4, human [Q07955-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Web resourcesi
Atlas of Genetics and Cytogenetics in Oncology and Haematology |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M72709 mRNA Translation: AAA35565.1 M72709 mRNA Translation: AAA35564.1 M69040 mRNA Translation: AAA03476.1 AB062124 mRNA Translation: BAB93456.1 AK312781 mRNA Translation: BAG35644.1 CH471109 Genomic DNA Translation: EAW94485.1 CH471109 Genomic DNA Translation: EAW94486.1 BC010264 mRNA Translation: AAH10264.1 BC033785 mRNA Translation: AAH33785.1 |
CCDSi | CCDS11600.1 [Q07955-1] CCDS58580.1 [Q07955-3] |
PIRi | A40040 B40040 C40040 |
RefSeqi | NP_001071634.1, NM_001078166.1 [Q07955-3] NP_008855.1, NM_006924.4 [Q07955-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1X4A | NMR | - | A | 1-96 | [»] | |
2M7S | NMR | - | A | 106-195 | [»] | |
2M8D | NMR | - | B | 107-196 | [»] | |
2O3D | NMR | - | A | 107-215 | [»] | |
3BEG | X-ray | 2.90 | B | 105-219 | [»] | |
4C0O | X-ray | 2.56 | C/D | 106-230 | [»] | |
BMRBi | Q07955 | |||||
SMRi | Q07955 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 112324, 229 interactors |
CORUMi | Q07955 |
DIPi | DIP-2155N |
IntActi | Q07955, 97 interactors |
MINTi | Q07955 |
STRINGi | 9606.ENSP00000258962 |
Chemistry databases
ChEMBLi | CHEMBL4295805 |
DrugBanki | DB09130, Copper |
PTM databases
iPTMneti | Q07955 |
PhosphoSitePlusi | Q07955 |
SwissPalmi | Q07955 |
Polymorphism and mutation databases
BioMutai | SRSF1 |
DMDMi | 730773 |
Proteomic databases
EPDi | Q07955 |
jPOSTi | Q07955 |
MassIVEi | Q07955 |
MaxQBi | Q07955 |
PaxDbi | Q07955 |
PeptideAtlasi | Q07955 |
PRIDEi | Q07955 |
ProteomicsDBi | 58560 [Q07955-1] 58561 [Q07955-2] 58562 [Q07955-3] |
TopDownProteomicsi | Q07955-1 [Q07955-1] Q07955-2 [Q07955-2] Q07955-3 [Q07955-3] |
Protocols and materials databases
Antibodypediai | 4585, 296 antibodies |
DNASUi | 6426 |
Genome annotation databases
Ensembli | ENST00000258962; ENSP00000258962; ENSG00000136450 [Q07955-1] ENST00000581979; ENSP00000463223; ENSG00000136450 [Q07955-3] ENST00000582730; ENSP00000462215; ENSG00000136450 [Q07955-3] |
GeneIDi | 6426 |
KEGGi | hsa:6426 |
UCSCi | uc002ivi.4, human [Q07955-1] |
Organism-specific databases
CTDi | 6426 |
DisGeNETi | 6426 |
EuPathDBi | HostDB:ENSG00000136450.12 |
GeneCardsi | SRSF1 |
HGNCi | HGNC:10780, SRSF1 |
HPAi | ENSG00000136450, Low tissue specificity |
MIMi | 600812, gene |
neXtProti | NX_Q07955 |
OpenTargetsi | ENSG00000136450 |
PharmGKBi | PA35696 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0105, Eukaryota |
GeneTreei | ENSGT00940000155585 |
HOGENOMi | CLU_012062_34_5_1 |
InParanoidi | Q07955 |
OrthoDBi | 1321443at2759 |
PhylomeDBi | Q07955 |
TreeFami | TF106261 |
Enzyme and pathway databases
PathwayCommonsi | Q07955 |
Reactomei | R-HSA-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-72163, mRNA Splicing - Major Pathway R-HSA-72165, mRNA Splicing - Minor Pathway R-HSA-72187, mRNA 3'-end processing R-HSA-73856, RNA Polymerase II Transcription Termination |
SIGNORi | Q07955 |
Miscellaneous databases
BioGRID-ORCSi | 6426, 759 hits in 852 CRISPR screens |
ChiTaRSi | SRSF1, human |
EvolutionaryTracei | Q07955 |
GeneWikii | ASF/SF2 |
GenomeRNAii | 6426 |
Pharosi | Q07955, Tbio |
PROi | PR:Q07955 |
RNActi | Q07955, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000136450, Expressed in oviduct epithelium and 252 other tissues |
ExpressionAtlasi | Q07955, baseline and differential |
Genevisiblei | Q07955, HS |
Family and domain databases
CDDi | cd12597, RRM1_SRSF1, 1 hit |
DisProti | DP01641 |
Gene3Di | 3.30.70.330, 2 hits |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom IPR029538, SRSF1 IPR034520, SRSF1_RRM1 |
PANTHERi | PTHR23147:SF44, PTHR23147:SF44, 1 hit |
Pfami | View protein in Pfam PF00076, RRM_1, 2 hits |
SMARTi | View protein in SMART SM00360, RRM, 2 hits |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SRSF1_HUMAN | |
Accessioni | Q07955Primary (citable) accession number: Q07955 Secondary accession number(s): B2R6Z7, D3DTZ3, Q13809 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 240 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations