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Protein

Ribosome maturation protein SDO1

Gene

SDO1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with the EF-2-like GTPase RIA1, may trigger the GTP-dependent release of TIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating TIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export.2 Publications

Miscellaneous

Present with 5060 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • guanyl-nucleotide exchange factor activity Source: SGD

GO - Biological processi

  • mature ribosome assembly Source: SGD

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processRibosome biogenesis

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:G3O-32183-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ribosome maturation protein SDO1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SDO1
Ordered Locus Names:YLR022C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XII

Organism-specific databases

Saccharomyces Genome Database

More...
SGDi
S000004012 SDO1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi31C → W: Impairs protein folding and stability. Loss of function. 1 Publication1
Mutagenesisi34N → I: Impairs protein folding and stability. Loss of function. 1 Publication1
Mutagenesisi71L → P: Impairs protein folding and stability. Loss of function. 1 Publication1

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL1741198

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001237641 – 250Ribosome maturation protein SDO1Add BLAST250

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q07953

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q07953

PRoteomics IDEntifications database

More...
PRIDEi
Q07953

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Associates with the 60S ribosomal subunit.

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
31296, 260 interactors

Protein interaction database and analysis system

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IntActi
Q07953, 16 interactors

Molecular INTeraction database

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MINTi
Q07953

STRING: functional protein association networks

More...
STRINGi
4932.YLR022C

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q07953

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q07953

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SDO1/SBDS family.Curated

Phylogenomic databases

Ensembl GeneTree

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GeneTreei
ENSGT00390000008135

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000216685

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q07953

KEGG Orthology (KO)

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KOi
K14574

Identification of Orthologs from Complete Genome Data

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OMAi
AVNPQMD

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.900, 1 hit
3.30.1250.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018978 Ribosome_mat_SBDS_C
IPR018023 Ribosome_mat_SBDS_CS
IPR019783 Ribosome_mat_SBDS_N
IPR036786 Ribosome_mat_SBDS_N_sf
IPR002140 Sdo1/SBDS
IPR039100 Sdo1/SBDS-like
IPR037188 Sdo1/SBDS_central_sf

The PANTHER Classification System

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PANTHERi
PTHR10927 PTHR10927, 1 hit
PTHR10927:SF1 PTHR10927:SF1, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01172 SBDS, 1 hit
PF09377 SBDS_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109728 SSF109728, 1 hit
SSF89895 SSF89895, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00291 RNA_SBDS, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01267 UPF0023, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q07953-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPINQPSGQI KLTNVSLVRL KKARKRFEVA CYQNKVQDYR KGIEKDLDEV
60 70 80 90 100
LQIHQVFMNV SKGLVANKED LQKCFGTTNV DDVIEEIMHK GEIQLSEKER
110 120 130 140 150
QLMLNKVNNE MLTIVSAKCI NPVSKKRYPP TMIHKALQEL KFSPVINKPA
160 170 180 190 200
KLQALEAIKL LVSKQIIPIV RAKMKVKVAI SEPSRQPELI EKISKLIASS
210 220 230 240 250
PGESTKPELD PWTCTGLIDP VNYRDLMTLC DKKGTVQVLD MAVIDNTTHN
Length:250
Mass (Da):28,283
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEFC799ADEFF73E0E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z73194 Genomic DNA Translation: CAA97545.1
BK006945 Genomic DNA Translation: DAA09340.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S64849

NCBI Reference Sequences

More...
RefSeqi
NP_013122.1, NM_001181909.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YLR022C_mRNA; YLR022C_mRNA; YLR022C

Database of genes from NCBI RefSeq genomes

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GeneIDi
850709

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YLR022C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73194 Genomic DNA Translation: CAA97545.1
BK006945 Genomic DNA Translation: DAA09340.1
PIRiS64849
RefSeqiNP_013122.1, NM_001181909.1

3D structure databases

ProteinModelPortaliQ07953
SMRiQ07953
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31296, 260 interactors
IntActiQ07953, 16 interactors
MINTiQ07953
STRINGi4932.YLR022C

Chemistry databases

ChEMBLiCHEMBL1741198

Proteomic databases

MaxQBiQ07953
PaxDbiQ07953
PRIDEiQ07953

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYLR022C_mRNA; YLR022C_mRNA; YLR022C
GeneIDi850709
KEGGisce:YLR022C

Organism-specific databases

SGDiS000004012 SDO1

Phylogenomic databases

GeneTreeiENSGT00390000008135
HOGENOMiHOG000216685
InParanoidiQ07953
KOiK14574
OMAiAVNPQMD

Enzyme and pathway databases

BioCyciYEAST:G3O-32183-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q07953

Family and domain databases

Gene3Di1.10.10.900, 1 hit
3.30.1250.10, 1 hit
InterProiView protein in InterPro
IPR018978 Ribosome_mat_SBDS_C
IPR018023 Ribosome_mat_SBDS_CS
IPR019783 Ribosome_mat_SBDS_N
IPR036786 Ribosome_mat_SBDS_N_sf
IPR002140 Sdo1/SBDS
IPR039100 Sdo1/SBDS-like
IPR037188 Sdo1/SBDS_central_sf
PANTHERiPTHR10927 PTHR10927, 1 hit
PTHR10927:SF1 PTHR10927:SF1, 1 hit
PfamiView protein in Pfam
PF01172 SBDS, 1 hit
PF09377 SBDS_C, 1 hit
SUPFAMiSSF109728 SSF109728, 1 hit
SSF89895 SSF89895, 1 hit
TIGRFAMsiTIGR00291 RNA_SBDS, 1 hit
PROSITEiView protein in PROSITE
PS01267 UPF0023, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSDO1_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q07953
Secondary accession number(s): D6VY24
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: January 16, 2019
This is version 145 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  4. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names
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