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Entry version 130 (18 Sep 2019)
Sequence version 1 (01 Nov 1996)
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Protein

FAS1 domain-containing protein YLR001C

Gene

YLR001C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Present with 206 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • macroautophagy Source: GO_Central

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:G3O-32162-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
FAS1 domain-containing protein YLR001C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:YLR001C
ORF Names:L1388
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XII

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:YLR001C

Saccharomyces Genome Database

More...
SGDi
S000003991 YLR001C

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini24 – 762VacuolarSequence analysisAdd BLAST739
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei763 – 783HelicalSequence analysisAdd BLAST21
Topological domaini784 – 862CytoplasmicSequence analysisAdd BLAST79

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane, Vacuole

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000024718124 – 862FAS1 domain-containing protein YLR001CAdd BLAST839

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi68N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi112N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi152N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi200N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi291N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi333N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi450N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi521N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi542N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi569N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi663N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi679N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi688N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q07895

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q07895

PRoteomics IDEntifications database

More...
PRIDEi
Q07895

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q07895

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
31274, 23 interactors

Database of interacting proteins

More...
DIPi
DIP-4383N

Protein interaction database and analysis system

More...
IntActi
Q07895, 1 interactor

Molecular INTeraction database

More...
MINTi
Q07895

STRING: functional protein association networks

More...
STRINGi
4932.YLR001C

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini34 – 162FAS1 1PROSITE-ProRule annotationAdd BLAST129
Domaini463 – 604FAS1 2PROSITE-ProRule annotationAdd BLAST142
Domaini606 – 744FAS1 3PROSITE-ProRule annotationAdd BLAST139

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000141914

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q07895

Identification of Orthologs from Complete Genome Data

More...
OMAi
NQGVIHP

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.180.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036378 FAS1_dom_sf
IPR000782 FAS1_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02469 Fasciclin, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF82153 SSF82153, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50213 FAS1, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q07895-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNMAIQTIKY IFWLLPILGL TQALLQNPGD DFPFSTVIDI LSENVEFSTF
60 70 80 90 100
LRIIQKTGHV QYLNELQNFT LFAPINSAFI KGDQTTDQFE EHFHIEDFLI
110 120 130 140 150
HDRVLQVRDL ENGTYLEKRA AKAPLLLRKH ERHCFVNEIA VVEPDLLPSF
160 170 180 190 200
QNASLQGINN LLLIQPQINE LLVQLDEETQ DLKIFSDFIS SFSNYNAYTN
210 220 230 240 250
SSTVLVPLDV NFRKFFNTIE INYLLDKYNK LGKSNTISQA KWAADRTSLL
260 270 280 290 300
QELIIDDVYG GILPKELILE NKNNRKLFMK SNSEGTSVSV NNSDYSPISN
310 320 330 340 350
RIFEIGVVHG FSDLDFLRTH IQFDAEKYLH GLNCSEFVKE LYFRDLEKFI
360 370 380 390 400
QNGRKITIFV PQASFNEDRG YTKPSLLYHF VEGKIDLEQD FSSLRPIQYA
410 420 430 440 450
PTQIYDSAFC SSAKRLGGHC QKFKITRSNK GYYINGRFKI LNTKPYEIGN
460 470 480 490 500
TSIYSIDDDL QLPGDLVLSL APENHCSISL MLLKELNLLD LPSNHKGYTI
510 520 530 540 550
LLPCMNSWDN NDLTIDYLRS NKTALNLLMR NLIFEDLIYS NNYSISTTVK
560 570 580 590 600
NLYGNSVSIG VQKIVGSQNL TKISVSTIKE SIIIEESSDI FFNQGVIHPI
610 620 630 640 650
DQLDFPVDLE ISLKELIETT GTKEIFDFFN LFYDLSSIIW NNEEYSLLVP
660 670 680 690 700
TASSIPLSGI TANSTNLRKF LELHLIPANV TQNLLDCNGS ISTKLGTKLN
710 720 730 740 750
CRKDHLDNVF VSIQGDWTKE VRVLKTGCTT NLKSSCIFLI DKPISLSWLN
760 770 780 790 800
SEKYHLRLPG IAVGFGVIIG VTIAISLLFC IIITRGGKVK DKNQRGRNDR
810 820 830 840 850
ATTPLIQHSP IIHNPSYSAT AHLSPLSQPT FEGSYSVNAI QTPRDIRRVG
860
SDQKGGRSVS TS
Length:862
Mass (Da):97,618
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5AD3E25DD69E13A1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X91488 Genomic DNA Translation: CAA62770.1
Z73173 Genomic DNA Translation: CAA97523.1
BK006945 Genomic DNA Translation: DAA09319.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S64821

NCBI Reference Sequences

More...
RefSeqi
NP_013101.1, NM_001181888.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YLR001C_mRNA; YLR001C; YLR001C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
850687

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YLR001C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X91488 Genomic DNA Translation: CAA62770.1
Z73173 Genomic DNA Translation: CAA97523.1
BK006945 Genomic DNA Translation: DAA09319.1
PIRiS64821
RefSeqiNP_013101.1, NM_001181888.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi31274, 23 interactors
DIPiDIP-4383N
IntActiQ07895, 1 interactor
MINTiQ07895
STRINGi4932.YLR001C

PTM databases

SwissPalmiQ07895

Proteomic databases

MaxQBiQ07895
PaxDbiQ07895
PRIDEiQ07895

Genome annotation databases

EnsemblFungiiYLR001C_mRNA; YLR001C; YLR001C
GeneIDi850687
KEGGisce:YLR001C

Organism-specific databases

EuPathDBiFungiDB:YLR001C
SGDiS000003991 YLR001C

Phylogenomic databases

HOGENOMiHOG000141914
InParanoidiQ07895
OMAiNQGVIHP

Enzyme and pathway databases

BioCyciYEAST:G3O-32162-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q07895

Family and domain databases

Gene3Di2.30.180.10, 2 hits
InterProiView protein in InterPro
IPR036378 FAS1_dom_sf
IPR000782 FAS1_domain
PfamiView protein in Pfam
PF02469 Fasciclin, 2 hits
SUPFAMiSSF82153 SSF82153, 4 hits
PROSITEiView protein in PROSITE
PS50213 FAS1, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYL001_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q07895
Secondary accession number(s): D6VY03
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: November 1, 1996
Last modified: September 18, 2019
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
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