UniProtKB - Q07798 (SPO75_YEAST)
Protein
Sporulation-specific protein 75
Gene
SPO75
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Acts as an osmosensitive calcium-permeable cation channel (By similarity). Required for spore wall assembly and ascus formation.By similarity2 Publications
GO - Molecular functioni
- calcium activated cation channel activity Source: GO_Central
GO - Biological processi
- ascospore formation Source: SGD
- ascospore wall assembly Source: SGD
Keywordsi
Molecular function | Ion channel |
Biological process | Ion transport, Sporulation, Transport |
Ligand | Calcium |
Protein family/group databases
TCDBi | 1.A.17.5.7, the calcium-dependent chloride channel (ca-clc) family |
Names & Taxonomyi
Protein namesi | Recommended name: Sporulation-specific protein 75 |
Gene namesi | Name:SPO75 Ordered Locus Names:YLL005C ORF Names:L1361 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YLL005C |
SGDi | S000003928, SPO75 |
Subcellular locationi
Other locations
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 34 | ExtracellularSequence analysisAdd BLAST | 34 | |
Transmembranei | 35 – 55 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 56 – 127 | CytoplasmicSequence analysisAdd BLAST | 72 | |
Transmembranei | 128 – 148 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 149 – 187 | ExtracellularSequence analysisAdd BLAST | 39 | |
Transmembranei | 188 – 208 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 209 – 481 | CytoplasmicSequence analysisAdd BLAST | 273 | |
Transmembranei | 482 – 502 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 503 – 527 | ExtracellularSequence analysisAdd BLAST | 25 | |
Transmembranei | 528 – 548 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 549 – 569 | CytoplasmicSequence analysisAdd BLAST | 21 | |
Transmembranei | 570 – 590 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 591 – 611 | ExtracellularSequence analysisAdd BLAST | 21 | |
Transmembranei | 612 – 632 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 633 – 660 | CytoplasmicSequence analysisAdd BLAST | 28 | |
Transmembranei | 661 – 683 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 684 – 692 | ExtracellularSequence analysis | 9 | |
Transmembranei | 693 – 713 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 714 – 730 | CytoplasmicSequence analysisAdd BLAST | 17 | |
Transmembranei | 731 – 751 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 752 – 753 | ExtracellularSequence analysis | 2 | |
Transmembranei | 754 – 774 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 775 – 868 | CytoplasmicSequence analysisAdd BLAST | 94 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000072143 | 1 – 868 | Sporulation-specific protein 75Add BLAST | 868 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 2 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 184 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 503 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | Q07798 |
PRIDEi | Q07798 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 31246, 90 interactors |
DIPi | DIP-8843N |
IntActi | Q07798, 3 interactors |
MINTi | Q07798 |
STRINGi | 4932.YLL005C |
Miscellaneous databases
RNActi | Q07798, protein |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1134, Eukaryota |
HOGENOMi | CLU_002458_2_0_1 |
InParanoidi | Q07798 |
OMAi | WINIVGR |
Family and domain databases
InterProi | View protein in InterPro IPR032880, Csc1_N IPR003864, RSN1_7TM |
Pfami | View protein in Pfam PF02714, RSN1_7TM, 1 hit PF13967, RSN1_TM, 1 hit |
i Sequence
Sequence statusi: Complete.
Q07798-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNATKELTFN LLNKFQDKER FGSAQRHAGI SLKGFISGIL FSFLYFLFQL
60 70 80 90 100
SLFIILRSRF KTIYQANVVL KIHPGSKVCF AKKKIKNYWS LFAFLKQLPG
110 120 130 140 150
RMLDPMEKFE RNERYGLDNY LFLRFLKLLI FFFAVLSIIN IPILIPIHYF
160 170 180 190 200
SRDILKENEG ERYEQSFRTT SKLDKWTMSN LSPNSSNTLI CHLFLSIFVV
210 220 230 240 250
LWFHFILSSE LRFVNRLGYS VLTKSKYQNI LYLEGFSSKL VTQSISLETF
260 270 280 290 300
FQPLHSDCFG VTHFIPKNLK KVHKLEIKLN KLQKSKEQII FEIILEKYFR
310 320 330 340 350
RVSIHRHLIA NHKRFFFSKL KNHLLFQYKK LVFLTQFRIS YYCTKIRLRW
360 370 380 390 400
KKSSIFPLYY PKLYVNTETI LERKYRILDK IIRKEKLIKF QVNSLKATSE
410 420 430 440 450
TKQALPDDLS SGTDIYMDKM FITFKSTLLS NVIGELLSYR LPTQNLKVII
460 470 480 490 500
GPNVNDIIWR NILDSSPLWK SAKYFSANIL RIFVIIGWIL PVAFLGLISQ
510 520 530 540 550
IPNISSLIPF TKIIHFQSPF IREVAKNLIP IVTLIIIIEI VPYFFRWLSY
560 570 580 590 600
LRGLKTGAQI EADVQNWYFV FVFIHLFVVV TISSGFSIII ERLLNNPVSI
610 620 630 640 650
PALLANDLPK CANFFCSFVL IRGMAYAGGN LLRIKELLFE LFYYKWKRST
660 670 680 690 700
PHAQFKRLKT SLFFQLGSIY PIFSVLGCIG IIYSVVAPII LLLCCISFSM
710 720 730 740 750
VFFSFSYLFK YQYNKENYSE TFGKLYIQAL MQLYAGIYFM EFCLLGLFTL
760 770 780 790 800
FDQYTLSTIM LVVFALTVIT HSKISKQIKS KPQRIPTLEY LSNLTEERKD
810 820 830 840 850
QFCQESYTFH DIFSICRNSD EIWLPRDKLG ISEEEQSFLE KSYHLKFDLN
860
MYSMNLFGDC HLENSHLH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X91488 Genomic DNA Translation: CAA62764.1 Z73110 Genomic DNA Translation: CAA97448.1 BK006945 Genomic DNA Translation: DAA09314.1 |
PIRi | S64747 |
RefSeqi | NP_013096.1, NM_001181825.1 |
Genome annotation databases
EnsemblFungii | YLL005C_mRNA; YLL005C; YLL005C |
GeneIDi | 850655 |
KEGGi | sce:YLL005C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X91488 Genomic DNA Translation: CAA62764.1 Z73110 Genomic DNA Translation: CAA97448.1 BK006945 Genomic DNA Translation: DAA09314.1 |
PIRi | S64747 |
RefSeqi | NP_013096.1, NM_001181825.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 31246, 90 interactors |
DIPi | DIP-8843N |
IntActi | Q07798, 3 interactors |
MINTi | Q07798 |
STRINGi | 4932.YLL005C |
Protein family/group databases
TCDBi | 1.A.17.5.7, the calcium-dependent chloride channel (ca-clc) family |
Proteomic databases
PaxDbi | Q07798 |
PRIDEi | Q07798 |
Genome annotation databases
EnsemblFungii | YLL005C_mRNA; YLL005C; YLL005C |
GeneIDi | 850655 |
KEGGi | sce:YLL005C |
Organism-specific databases
EuPathDBi | FungiDB:YLL005C |
SGDi | S000003928, SPO75 |
Phylogenomic databases
eggNOGi | KOG1134, Eukaryota |
HOGENOMi | CLU_002458_2_0_1 |
InParanoidi | Q07798 |
OMAi | WINIVGR |
Miscellaneous databases
PROi | PR:Q07798 |
RNActi | Q07798, protein |
Family and domain databases
InterProi | View protein in InterPro IPR032880, Csc1_N IPR003864, RSN1_7TM |
Pfami | View protein in Pfam PF02714, RSN1_7TM, 1 hit PF13967, RSN1_TM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SPO75_YEAST | |
Accessioni | Q07798Primary (citable) accession number: Q07798 Secondary accession number(s): D6VXZ8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 16, 2005 |
Last sequence update: | November 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 130 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast chromosome XII
Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names - SIMILARITY comments
Index of protein domains and families - Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD