UniProtKB - Q07655 (WHI4_YEAST)
Protein
Protein WHI4
Gene
WHI4
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Has a partially redundant function to WHI3, a dosage-dependent modulator of cell size.1 Publication
GO - Molecular functioni
- mRNA binding Source: SGD
GO - Biological processi
- mRNA destabilization Source: SGD
- regulation of cell size Source: SGD
Keywordsi
Molecular function | RNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Protein WHI4 |
Gene namesi | Name:WHI4 Ordered Locus Names:YDL224C ORF Names:D0839 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YDL224C |
SGDi | S000002383, WHI4 |
Subcellular locationi
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000262756 | 1 – 649 | Protein WHI4Add BLAST | 649 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 22 | PhosphoserineCombined sources | 1 | |
Modified residuei | 206 | PhosphoserineCombined sources | 1 | |
Modified residuei | 258 | PhosphoserineCombined sources | 1 | |
Modified residuei | 283 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Phosphorylated by PKA in vitro.1 Publication
Keywords - PTMi
PhosphoproteinProteomic databases
MaxQBi | Q07655 |
PaxDbi | Q07655 |
PRIDEi | Q07655 |
PTM databases
iPTMneti | Q07655 |
Expressioni
Inductioni
Cell cycle-regulated. Expression peaks during S/G2 phase.1 Publication
Interactioni
Protein-protein interaction databases
BioGRIDi | 31822, 90 interactors |
DIPi | DIP-4321N |
IntActi | Q07655, 8 interactors |
MINTi | Q07655 |
STRINGi | 4932.YDL224C |
Miscellaneous databases
RNActi | Q07655, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 533 – 625 | RRMPROSITE-ProRule annotationAdd BLAST | 93 |
Phylogenomic databases
eggNOGi | KOG0118, Eukaryota |
GeneTreei | ENSGT00940000176750 |
HOGENOMi | CLU_018359_0_0_1 |
InParanoidi | Q07655 |
OMAi | THYANIL |
Family and domain databases
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
i Sequence
Sequence statusi: Complete.
Q07655-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLVHNQTNL NESKFLIERA FSSSSETVPL SKEATYPMPT AYSFSAVRSN
60 70 80 90 100
SETNIKRENP QGFAKEPIMT SMLHNLTMST GKGNGNDVNS LAPHDVDVGP
110 120 130 140 150
YCLLLRNLPK DITLRECYCI FSLATGVSSI ELKRDDREPF NDNEKVVVVK
160 170 180 190 200
FGSLSLVTHY ANILNSKSEI FGPSFPFRSH IDVVNEQTQL PVSFQEHVSS
210 220 230 240 250
GTTNSSPKNY QLSSSAQNEI QNQSFNTISY GKTSSSPLGP SAAKPRPSLL
260 270 280 290 300
SERSLRFSFN DPFGLETISQ RKESVPFLRN SISQHDLSNV TTTPVPAGMP
310 320 330 340 350
PQKDAGKSLL LLEKDEINES IWNGDELVND VGNSSFGASL QEPPMSSTPV
360 370 380 390 400
MEWNASSTAN IPLFQLSSQE NHQSNLLPPS HHSISQDVPH IQSQPNLNNS
410 420 430 440 450
GVIHSATSLP HYHLLNQINA STKTQSIQQS VSNVPSNLDL NLQTENGHPQ
460 470 480 490 500
SSAPNGSSIF NNQKVNQGFL VSEQDTSTIS RQKECSSTAS ASAFSKNNET
510 520 530 540 550
NVAGSTTISQ ADLSLLAKVP PPANPADQNP PCNTLYVGNL PPDATEQELR
560 570 580 590 600
QLFSNQQGFR RLSFRNKMNS HGHGNGHGHG PICFVEFEDV SFATRALAEL
610 620 630 640
YGSQLPHPRP SLNNKGGIRL SFSKNPLGVR GSNSRSKSGY SFNGSYGKS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z74272 Genomic DNA Translation: CAA98803.1 BK006938 Genomic DNA Translation: DAA11641.1 |
PIRi | S67787 |
RefSeqi | NP_010057.1, NM_001180284.1 |
Genome annotation databases
EnsemblFungii | YDL224C_mRNA; YDL224C; YDL224C |
GeneIDi | 851302 |
KEGGi | sce:YDL224C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z74272 Genomic DNA Translation: CAA98803.1 BK006938 Genomic DNA Translation: DAA11641.1 |
PIRi | S67787 |
RefSeqi | NP_010057.1, NM_001180284.1 |
3D structure databases
SMRi | Q07655 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 31822, 90 interactors |
DIPi | DIP-4321N |
IntActi | Q07655, 8 interactors |
MINTi | Q07655 |
STRINGi | 4932.YDL224C |
PTM databases
iPTMneti | Q07655 |
Proteomic databases
MaxQBi | Q07655 |
PaxDbi | Q07655 |
PRIDEi | Q07655 |
Genome annotation databases
EnsemblFungii | YDL224C_mRNA; YDL224C; YDL224C |
GeneIDi | 851302 |
KEGGi | sce:YDL224C |
Organism-specific databases
EuPathDBi | FungiDB:YDL224C |
SGDi | S000002383, WHI4 |
Phylogenomic databases
eggNOGi | KOG0118, Eukaryota |
GeneTreei | ENSGT00940000176750 |
HOGENOMi | CLU_018359_0_0_1 |
InParanoidi | Q07655 |
OMAi | THYANIL |
Miscellaneous databases
PROi | PR:Q07655 |
RNActi | Q07655, protein |
Family and domain databases
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | WHI4_YEAST | |
Accessioni | Q07655Primary (citable) accession number: Q07655 Secondary accession number(s): D6VRD1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 28, 2006 |
Last sequence update: | November 1, 1996 | |
Last modified: | October 7, 2020 | |
This is version 142 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome IV
Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names