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Entry version 117 (29 Sep 2021)
Sequence version 1 (01 Nov 1996)
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Protein

UPF0592 protein YDL073W

Gene

YDL073W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
UPF0592 protein YDL073W
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:YDL073W
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

Saccharomyces Genome Database

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SGDi
S000002231, YDL073W

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:YDL073W

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Cells are viable and do not display any phenotype.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002484601 – 984UPF0592 protein YDL073WAdd BLAST984

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q07454

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q07454

PRoteomics IDEntifications database

More...
PRIDEi
Q07454

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q07454

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
31988, 71 interactors

Protein interaction database and analysis system

More...
IntActi
Q07454, 7 interactors

Molecular INTeraction database

More...
MINTi
Q07454

STRING: functional protein association networks

More...
STRINGi
4932.YDL073W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q07454, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni675 – 712DisorderedSequence analysisAdd BLAST38

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPF0592 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG502QQ52, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006978_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q07454

Identification of Orthologs from Complete Genome Data

More...
OMAi
WHYWYII

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR013887, UPF0592

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08578, DUF1765, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q07454-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGPAIHNQLY ECGLKTTSQD GFLMDNYETQ LFQSLNRFIN FINNANQSAS
60 70 80 90 100
NKEQNTKFCK SSSNFLRLKL LTVLRQWCDS SRSNCTLEVR DVLTQWWVTL
110 120 130 140 150
LNFLNSDTSL QIDTALELSL SIELTSVCLE CLSKIMTILI ILPFHSSRDM
160 170 180 190 200
EIYSHHLLLT IHCITNKLIL ISKNSKKLKR TNSDDKCSIN DKKLQYLNKY
210 220 230 240 250
SSLLRAFIGK LNAYAFFYLP EDFHFDTILL LTVSPQISSS IQTSLFSWKK
260 270 280 290 300
RQYKFTDDQG QMIRTEAFEN KDTKFFKIIV SYIKNDFVLM SFYWHYWYII
310 320 330 340 350
LQFMKFSDSD VGIKKSTLSC IPGSEILLTH VTTRFLNSDL NKFTRIIKQT
360 370 380 390 400
PNPRIANENV TESHPNFKSL NSSNALITSE RINDYVFSNF KTIKLWECLR
410 420 430 440 450
SLSGCILKEN HPEYLENMLS LHESLLIDYV STISAYDYIA ANVIYNKVLQ
460 470 480 490 500
FIIFQFESLP SLKFIQWRSW YNGLLSMLRT KNVNCQTVSL LCLFNIWKHV
510 520 530 540 550
TIEDRDEIVK VLLSDFWESL IFENEFPLIR ILFMKVLVFK IIPSVQNSSS
560 570 580 590 600
LRFLPHDRIK QLYEELLVNK EELFEMQKHD SNDIVAHRKN ALVFNGNSRL
610 620 630 640 650
MMIPKKPNTE DHLVYKINHD KNLTTERFPS VSSVANTRPN VILKNGKYAY
660 670 680 690 700
DILDEMTSKA AFLLAEKKTR LNPKKNHKIM DGYEGGQENE DNDEDSEDSG
710 720 730 740 750
SHKNKRKEGN SSLSATLNTW LSKFSSTSED SQKKKEQANE LGNDFEYDED
760 770 780 790 800
VADFAEILPK QSSSNIEKIF KHGNNSGSMV SYNSSIKLNR RENILIGPPE
810 820 830 840 850
LRFSNEIKEH NSIATIFKLV FIQTNRRVVE KIDLANMKWG TIHGGSKYMK
860 870 880 890 900
PLPVPKDLVA SVAKNESETR NLATLCGNGL DFEIPVPDFN IFGKCMEDEQ
910 920 930 940 950
DVAKIGNQNV EDLKVTGGRE VTIWKQIQDM KLRTRIQKIC VLIETFNATV
960 970 980
REYFEFSNRL EHDGIFIDFE VRKPSSNNSI NIKV
Length:984
Mass (Da):113,891
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9854EBE15C88DF0B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
Z74121 Genomic DNA Translation: CAA98639.1
BK006938 Genomic DNA Translation: DAA11786.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S67609

NCBI Reference Sequences

More...
RefSeqi
NP_010210.1, NM_001180132.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YDL073W_mRNA; YDL073W; YDL073W

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
851486

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YDL073W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z74121 Genomic DNA Translation: CAA98639.1
BK006938 Genomic DNA Translation: DAA11786.1
PIRiS67609
RefSeqiNP_010210.1, NM_001180132.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi31988, 71 interactors
IntActiQ07454, 7 interactors
MINTiQ07454
STRINGi4932.YDL073W

PTM databases

iPTMnetiQ07454

Proteomic databases

MaxQBiQ07454
PaxDbiQ07454
PRIDEiQ07454

Genome annotation databases

EnsemblFungiiYDL073W_mRNA; YDL073W; YDL073W
GeneIDi851486
KEGGisce:YDL073W

Organism-specific databases

SGDiS000002231, YDL073W
VEuPathDBiFungiDB:YDL073W

Phylogenomic databases

eggNOGiENOG502QQ52, Eukaryota
HOGENOMiCLU_006978_0_0_1
InParanoidiQ07454
OMAiWHYWYII

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q07454
RNActiQ07454, protein

Family and domain databases

InterProiView protein in InterPro
IPR013887, UPF0592
PfamiView protein in Pfam
PF08578, DUF1765, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYD073_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q07454
Secondary accession number(s): D6VRS6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: November 1, 1996
Last modified: September 29, 2021
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  4. SIMILARITY comments
    Index of protein domains and families
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