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UniProtKB - Q07423 (HEX6_RICCO)
Protein
Hexose carrier protein HEX6
Gene
HEX6
Organism
Ricinus communis (Castor bean)
Status
Functioni
Active uptake of hexoses. Probable glucose/hydrogen symport.
GO - Molecular functioni
- monosaccharide transmembrane transporter activity Source: InterPro
- symporter activity Source: UniProtKB-KW
Keywordsi
Biological process | Sugar transport, Symport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Hexose carrier protein HEX6 |
Gene namesi | Name:HEX6 |
Organismi | Ricinus communis (Castor bean) |
Taxonomic identifieri | 3988 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › fabids › Malpighiales › Euphorbiaceae › Acalyphoideae › Acalypheae › Ricinus |
Subcellular locationi
Other locations
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 22 | CytoplasmicSequence analysisAdd BLAST | 22 | |
Transmembranei | 23 – 43 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 83 – 103 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 118 – 128 | Helical; Name=3Sequence analysisAdd BLAST | 11 | |
Transmembranei | 140 – 160 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Transmembranei | 169 – 189 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 202 – 222 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Transmembranei | 284 – 304 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Transmembranei | 325 – 345 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Transmembranei | 349 – 369 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Transmembranei | 382 – 402 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Transmembranei | 428 – 448 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Transmembranei | 451 – 471 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 472 – 510 | CytoplasmicSequence analysisAdd BLAST | 39 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050445 | 1 – 510 | Hexose carrier protein HEX6Add BLAST | 510 |
Structurei
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
InParanoidi | Q07423 |
Family and domain databases
CDDi | cd17361, MFS_STP, 1 hit |
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR044778, MFS_STP/MST-like_plant IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR045262, STP/PLT_plant IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23500, PTHR23500, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q07423-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAGLAITSE GGQYNGRMTS FVALSCMMAA MGGVIFGYDI GVSGGVTSMD
60 70 80 90 100
PFLKKFFPDV YRKMKEDTEI SNYCKFDSQL LTSFTSSLYV AGLVASFFAS
110 120 130 140 150
SVTRAFGRKP SILLGGXVFL AXAALGGAAV NVYMLIFGRV LLGVGVGFAN
160 170 180 190 200
QAVPLYLSEM APPRYRGAIN NGFQFSVGIG ALSANLINYG TEKIEGGWGW
210 220 230 240 250
RISLAMAAVP AAILTFGALF LPETPNSLIQ RSNDHERAKL MLQRVRGTTD
260 270 280 290 300
VQAELDDLIK ASIISRTIQH PFKNIMRRKY RPQLVMAVAI PFFQQVTGIN
310 320 330 340 350
VIAFYAPILF RTIGLEESAS LLSSIVTGLV GSASTFISML IVDKLGRRAL
360 370 380 390 400
FIFGGVQMFV AQIMVGSIMA AELGDHGGIG KGYAYIVLIL ICIYVAGFGW
410 420 430 440 450
SWGPLGWLVP SEIFPLEIRS AGQSIVVAVS FLFTFVVAQT FLSMLCHFKS
460 470 480 490 500
GIFFFFGGWV VVMTAFVHFL LPETKKVPIE KMDIVWRDHW FWKKIIGEEA
510
AEENNKMEAA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L08188 mRNA Translation: AAA79857.1 |
PIRi | T10124 |
RefSeqi | NP_001310704.1, NM_001323775.1 |
Genome annotation databases
GeneIDi | 8289638 |
KEGGi | rcu:8289638 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L08188 mRNA Translation: AAA79857.1 |
PIRi | T10124 |
RefSeqi | NP_001310704.1, NM_001323775.1 |
3D structure databases
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3988.XP_002510991.1 |
Genome annotation databases
GeneIDi | 8289638 |
KEGGi | rcu:8289638 |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
InParanoidi | Q07423 |
Family and domain databases
CDDi | cd17361, MFS_STP, 1 hit |
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR044778, MFS_STP/MST-like_plant IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR045262, STP/PLT_plant IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23500, PTHR23500, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | HEX6_RICCO | |
Accessioni | Q07423Primary (citable) accession number: Q07423 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 23, 2022 | |
This is version 84 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |