HEX6

Functionⁱ

Active uptake of hexoses. Probable glucose/hydrogen symport.

GO - Molecular functionⁱ

symporter activity Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

carbohydrate transport Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Sugar transport, Symport, Transport

Biological process

Sugar transport, Symport, Transport

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Hexose carrier protein HEX6
Gene namesⁱ	Name:HEX6
Organismⁱ	Ricinus communis (Castor bean)
Taxonomic identifierⁱ	3988 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Mesangiospermae › eudicotyledons › Gunneridae › Pentapetalae › rosids › fabids › Malpighiales › Euphorbiaceae › Acalyphoideae › Acalypheae › Ricinus

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 22	CytoplasmicSequence analysisAdd BLAST	22
Transmembraneⁱ	23 – 43	Helical; Name=1Sequence analysisAdd BLAST	21
Transmembraneⁱ	83 – 103	Helical; Name=2Sequence analysisAdd BLAST	21
Transmembraneⁱ	118 – 128	Helical; Name=3Sequence analysisAdd BLAST	11
Transmembraneⁱ	140 – 160	Helical; Name=4Sequence analysisAdd BLAST	21
Transmembraneⁱ	169 – 189	Helical; Name=5Sequence analysisAdd BLAST	21
Transmembraneⁱ	202 – 222	Helical; Name=6Sequence analysisAdd BLAST	21
Transmembraneⁱ	284 – 304	Helical; Name=7Sequence analysisAdd BLAST	21
Transmembraneⁱ	325 – 345	Helical; Name=8Sequence analysisAdd BLAST	21
Transmembraneⁱ	349 – 369	Helical; Name=9Sequence analysisAdd BLAST	21
Transmembraneⁱ	382 – 402	Helical; Name=10Sequence analysisAdd BLAST	21
Transmembraneⁱ	428 – 448	Helical; Name=11Sequence analysisAdd BLAST	21
Transmembraneⁱ	451 – 471	Helical; Name=12Sequence analysisAdd BLAST	21
Topological domainⁱ	472 – 510	CytoplasmicSequence analysisAdd BLAST	39

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000050445	1 – 510	Hexose carrier protein HEX6Add BLAST		510

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidⁱ	Q07423

InParanoidⁱ

Q07423

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd06174 MFS, 1 hit
InterProⁱ	View protein in InterPro IPR020846 MFS_dom IPR005828 MFS_sugar_transport-like IPR036259 MFS_trans_sf IPR003663 Sugar/inositol_transpt IPR005829 Sugar_transporter_CS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00083 Sugar_tr, 1 hit
PRINTSⁱ	PR00171 SUGRTRNSPORT
SUPFAMⁱ	SSF103473 SSF103473, 1 hit
TIGRFAMsⁱ	TIGR00879 SP, 1 hit
PROSITEⁱ	View protein in PROSITE PS50850 MFS, 1 hit PS00216 SUGAR_TRANSPORT_1, 1 hit PS00217 SUGAR_TRANSPORT_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q07423-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAAGLAITSE GGQYNGRMTS FVALSCMMAA MGGVIFGYDI GVSGGVTSMD 
        60         70         80         90        100
PFLKKFFPDV YRKMKEDTEI SNYCKFDSQL LTSFTSSLYV AGLVASFFAS 
       110        120        130        140        150
SVTRAFGRKP SILLGGXVFL AXAALGGAAV NVYMLIFGRV LLGVGVGFAN 
       160        170        180        190        200
QAVPLYLSEM APPRYRGAIN NGFQFSVGIG ALSANLINYG TEKIEGGWGW 
       210        220        230        240        250
RISLAMAAVP AAILTFGALF LPETPNSLIQ RSNDHERAKL MLQRVRGTTD 
       260        270        280        290        300
VQAELDDLIK ASIISRTIQH PFKNIMRRKY RPQLVMAVAI PFFQQVTGIN 
       310        320        330        340        350
VIAFYAPILF RTIGLEESAS LLSSIVTGLV GSASTFISML IVDKLGRRAL 
       360        370        380        390        400
FIFGGVQMFV AQIMVGSIMA AELGDHGGIG KGYAYIVLIL ICIYVAGFGW 
       410        420        430        440        450
SWGPLGWLVP SEIFPLEIRS AGQSIVVAVS FLFTFVVAQT FLSMLCHFKS 
       460        470        480        490        500
GIFFFFGGWV VVMTAFVHFL LPETKKVPIE KMDIVWRDHW FWKKIIGEEA 
       510
AEENNKMEAA

Length:510

Mass (Da):55,597

Last modified:October 1, 1996 - v1

Checksum:ⁱ26615F8EBD84299E

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L08188 mRNA Translation: AAA79857.1
PIRⁱ	T10124
NCBI Reference Sequences More...RefSeqⁱ	NP_001310704.1, NM_001323775.1

Genome annotation databases

GeneIDⁱ	8289638
KEGGⁱ	rcu:8289638

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q07423	Sugar transporter, putative		RICCO		510	UniRef90_Q07423
UPI000772C4BC		RICCO		447

Protein	Similar proteins		Species	Score	Length	Source
Q07423	Sugar transport protein 4		ARATH		514	UniRef50_Q39228
Sugar transport protein MST3		ORYSJ		518
Sugar transport protein 4		NOCCA		514
Uncharacterized protein		Capsella rubella		514
Uncharacterized protein		Brassica oleracea var. oleracea		514
+1240

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L08188 mRNA Translation: AAA79857.1
PIRⁱ	T10124
RefSeqⁱ	NP_001310704.1, NM_001323775.1

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	8289638
KEGGⁱ	rcu:8289638

Phylogenomic databases

InParanoidⁱ	Q07423

InParanoidⁱ

Q07423

Family and domain databases

CDDⁱ	cd06174 MFS, 1 hit
InterProⁱ	View protein in InterPro IPR020846 MFS_dom IPR005828 MFS_sugar_transport-like IPR036259 MFS_trans_sf IPR003663 Sugar/inositol_transpt IPR005829 Sugar_transporter_CS
Pfamⁱ	View protein in Pfam PF00083 Sugar_tr, 1 hit
PRINTSⁱ	PR00171 SUGRTRNSPORT
SUPFAMⁱ	SSF103473 SSF103473, 1 hit
TIGRFAMsⁱ	TIGR00879 SP, 1 hit
PROSITEⁱ	View protein in PROSITE PS50850 MFS, 1 hit PS00216 SUGAR_TRANSPORT_1, 1 hit PS00217 SUGAR_TRANSPORT_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	HEX6_RICCO
Accessionⁱ	Q07423Primary (citable) accession number: Q07423
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
	Last sequence update:	October 1, 1996
	Last modified:	November 7, 2018
	This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Plant Protein Annotation Program

Miscellaneousⁱ

Documents

SIMILARITY comments
Index of protein domains and families

UniProtKB - Q07423 (HEX6_RICCO)

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Hexose carrier protein HEX6

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Other locations

Other locations

Topology

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Molecule processing

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Documents

UniProt is an ELIXIR core data resource

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UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q07423 (HEX6_RICCO)

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Hexose carrier protein HEX6

HEX6

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Other locations

Topology

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ