Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alcohol dehydrogenase 1

Gene

ADH1

Organism
Zea luxurians (Guatemalan teosinte) (Euchlaena luxurians)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

A primary alcohol + NAD+ = an aldehyde + NADH.By similarity
A secondary alcohol + NAD+ = a ketone + NADH.By similarity

Cofactori

Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi26Zinc 2By similarity1
Metal bindingi29Zinc 2By similarity1
Metal bindingi32Zinc 2By similarity1
Metal bindingi40Zinc 2By similarity1
Metal bindingi104Zinc 1; catalyticBy similarity1
Binding sitei153NADBy similarity1
Binding sitei158NADBy similarity1
Binding sitei199NAD; via carbonyl oxygenBy similarity1
Binding sitei222NAD; via carbonyl oxygenBy similarity1
Binding sitei249NAD; via amide nitrogenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi129 – 134NADBy similarity6
Nucleotide bindingi222 – 224NADBy similarity3

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandMetal-binding, NAD, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Alcohol dehydrogenase 1 (EC:1.1.1.1By similarity)
Gene namesi
Name:ADH1
OrganismiZea luxurians (Guatemalan teosinte) (Euchlaena luxurians)
Taxonomic identifieri15945 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000160704‹1 – ›293Alcohol dehydrogenase 1Add BLAST›293

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ07264
SMRiQ07264
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR013149 ADH_C
IPR013154 ADH_N
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF08240 ADH_N, 1 hit
PF00107 ADH_zinc_N, 1 hit
SUPFAMiSSF50129 SSF50129, 1 hit
SSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Fragment.

Q07264-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
IIESVGEGVT DVAPGDHVLP VFTGECKECA HCKSAESNMC DLLRINTDRG
60 70 80 90 100
VMIGDGKSRF SINGKPIYHF VGTSTFSEYT VMHVGCVAKI NPQAPLDKVC
110 120 130 140 150
VLSCGISTGL GASINVAKPP KGSTVAVFGL GAVGLAAAEG ARIAGASRII
160 170 180 190 200
GVDLNPSRFE EARKFGCTEF VNPKDHNKPV QEVLAEMTNG GVDRSVECTG
210 220 230 240 250
NINAMIQAFE CVHDGWGVAV LVGVPHKDAE FKTHPMNFLN ERTLKGTFFG
260 270 280 290
NYKPRTDLPN VVELYMKKEL EVEKFITHSV PFAEINKAFD LMA
Length:293
Mass (Da):31,490
Last modified:February 1, 1996 - v2
Checksum:iE1B343AE6EF9CBD4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Non-terminal residuei2931

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L08588 Genomic DNA Translation: AAA74639.1
L08590 Genomic DNA Translation: AAA74641.1
UniGeneiZm.1540
Zm.92834

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L08588 Genomic DNA Translation: AAA74639.1
L08590 Genomic DNA Translation: AAA74641.1
UniGeneiZm.1540
Zm.92834

3D structure databases

ProteinModelPortaliQ07264
SMRiQ07264
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR013149 ADH_C
IPR013154 ADH_N
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF08240 ADH_N, 1 hit
PF00107 ADH_zinc_N, 1 hit
SUPFAMiSSF50129 SSF50129, 1 hit
SSF51735 SSF51735, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiADH1_ZEALU
AccessioniPrimary (citable) accession number: Q07264
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1996
Last modified: November 22, 2017
This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again