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Entry version 62 (07 Apr 2021)
Sequence version 1 (31 Oct 2006)
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Protein
Submitted name:

Nonribosomal peptide synthetase

Gene

endC

Organism
Streptomyces fungicidicus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pantetheine 4'-phosphateARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nonribosomal peptide synthetaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:endCImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptomyces fungicidicusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri68203 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei996O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei2057O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei3122O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei4188O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei5254O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei6313O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei7388O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei8458O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotationARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini959 – 1035CarrierInterPro annotationAdd BLAST77
Domaini2022 – 2097CarrierInterPro annotationAdd BLAST76
Domaini3087 – 3161CarrierInterPro annotationAdd BLAST75
Domaini4153 – 4228CarrierInterPro annotationAdd BLAST76
Domaini5219 – 5293CarrierInterPro annotationAdd BLAST75
Domaini6278 – 6353CarrierInterPro annotationAdd BLAST76
Domaini7353 – 7427CarrierInterPro annotationAdd BLAST75
Domaini8423 – 8497CarrierInterPro annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni204 – 223DisorderedSequence analysisAdd BLAST20

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 5 hits
3.30.559.10, 8 hits
3.40.50.12780, 8 hits
3.40.50.1820, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010071, AA_adenyl_domain
IPR029058, AB_hydrolase
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR020806, PKS_PP-bd
IPR020802, PKS_thioesterase
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
IPR001031, Thioesterase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00501, AMP-binding, 8 hits
PF13193, AMP-binding_C, 8 hits
PF00668, Condensation, 8 hits
PF00550, PP-binding, 8 hits
PF00975, Thioesterase, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00823, PKS_PP, 8 hits
SM00824, PKS_TE, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336, SSF47336, 8 hits
SSF53474, SSF53474, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01733, AA-adenyl-dom, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00455, AMP_BINDING, 8 hits
PS50075, CARRIER, 8 hits
PS00012, PHOSPHOPANTETHEINE, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q06YZ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIPLSFAQRR LWFLWKLEGA ATTFNIPLTL RLRGTLDREA MDAALRDVIG
60 70 80 90 100
RHEVLRTVLP AVDGEPYQRI LPLRETGFEL GVVQVPPEDA EAAVRRASTY
110 120 130 140 150
AFDLAEEIPV RADLFEVGPD EHVLALVVHH IAADGWSIGP LMRDLSTAYT
160 170 180 190 200
ARLAGRAPRW EPLPVQYADY ALWQRELLGT GDDPESTLSE QVAYWRRTLA
210 220 230 240 250
GAPEELELPT DRPRPAQTTP RGHTAELELP ADTHRRLREL AGDHGASLLM
260 270 280 290 300
VAQSALAVLL SRTGAGEDLP MGTLVAGRND EGLNDLVGFF VNNLVIRADL
310 320 330 340 350
SGDPTFTEVL ERVREASLDA YEYQDVPFEK LVEELSPTRS LARHPLFQVM
360 370 380 390 400
AAVETGDPMS TGPGGGPALE LPGLRVEMLS DDQQARDLDL DLVLRETHDG
410 420 430 440 450
DGRPAGLRGA LIGAADLFDA GTVQRIADML ARVLEQVATT PTAHVRSLDV
460 470 480 490 500
LDPEEQRRLL GVGSGAVVEV PGGSLPELFA AQARLSPDAV ALVGSGVELS
510 520 530 540 550
YREVDARANR LARKLIGRGV GPESVVALVL ERSPELVIAV LAVLKAGGAY
560 570 580 590 600
VAVDPGQPAD RIRFVIEDAS PVLVIDDLNF LAETEDFDDF PVTDADRISP
610 620 630 640 650
LLPSHPAYVI YTSGSTGRPK GVLISHAACV SYVASHVRYG VSESSRVAQF
660 670 680 690 700
ASAGFDAFCE EWWLALLGGG ALVVVPSERR LGEELVRFLL EERVTHATLP
710 720 730 740 750
PAVAVLMREE ALAPGFVLDV GGEVCPPDLV DRWVAAGRTL FNSYGPSEAT
760 770 780 790 800
VNVTVWQAVD GSLGAGVPIG RPVGNTRLYV LDDGLRPVPV GVLGELYVSG
810 820 830 840 850
VQLGRGYLGR AGLTAERFVA CPYASGERMY RTGDRVKWNA EGELVFAGRA
860 870 880 890 900
DDQVKVRGFR IEPGEVETVL AAHPAVAHAA VVVREDTPGD KRLTAYVVPR
910 920 930 940 950
TPGTGVGAAA VARVAERLPA YMVPSAVVEL DALPLTANGK LDREALPVPE
960 970 980 990 1000
YQGAGGGRAP ENAQEELVCQ AFAEVFGVDR AAVGVEDDFF ALGGHSLLAV
1010 1020 1030 1040 1050
SLVEWLRRRG VSVSVRALFV SATPAALAAA AGPEPVTVPP NLIPDGATEI
1060 1070 1080 1090 1100
TPDMLTLVEL TEEEIARVAA AVPGGAANIA DIYPLAPLQE GLLFHHLMTD
1110 1120 1130 1140 1150
GDGTDVYITP AVVEFDSRDR LDDFFAALRW MVDRHDIYRT AVVSDGLREP
1160 1170 1180 1190 1200
VQVVVRHAEL TVEETVLDAD GPDPVEQMLA LGGRRMELNR VPLMSAHIAA
1210 1220 1230 1240 1250
DPGGDRWLAL LRIHHLLQDH TTQDVLFDDL WAFLAGRADA LPPPLPFRDF
1260 1270 1280 1290 1300
VAQSRLGTPR EEHERYFAEL LGDVTETTAP YGLTDVHGDG SGSEQARLRL
1310 1320 1330 1340 1350
DDALAARVRR AARTLGASPA TLFHLAWARV LGAVSGRDDV VFGTVLFGRM
1360 1370 1380 1390 1400
NAGEGADRVP GLFINTLPVR VRLDRQSVAE ALTGLRRDLA DLLVHEHAPL
1410 1420 1430 1440 1450
TLAQAACGLP GGSPLFTSIL NYRHNTNGPH ESRAELDGMQ VLSARDLTNY
1460 1470 1480 1490 1500
PLAVAVDADT AGFTVTVDAV TPADPARVGA LLTTCLESLT SAIQDEPATP
1510 1520 1530 1540 1550
LRMVEVLDGA ELTALLDGWN DTAVPAPDAS LPEAFAATVA AAPDAVALVC
1560 1570 1580 1590 1600
GDDRITYAEL DARADRLART LVASGVRPES AVAVAMERSA DLVVALLAVS
1610 1620 1630 1640 1650
KAGGVFVPLD AGWPAARTRA VIEDADACLV LVDGTTAGLE AGVALLRVDA
1660 1670 1680 1690 1700
TTDTVVDLPG PVPPDGAAYV MYTSGSTGVP KGVVTTHKDL VRLATDRCWG
1710 1720 1730 1740 1750
TTPRVLFHAP HAFDASCYEL WVPLLSGGTV VIAPRERVDA ALMRRLTTAH
1760 1770 1780 1790 1800
RLTHVHVTAG LLRVLADDDP GCFDGVREVL TGGDVVPADA VRRILDANPR
1810 1820 1830 1840 1850
AVVRHMYGPT EVTLCATQHE VADAAEVDGV LPIGRPLDNT RVYVLDDGLN
1860 1870 1880 1890 1900
VVPVGVTGEL YVAGSGLARG YANRAESTAE RFVACPFGPG ERMYRTGDLA
1910 1920 1930 1940 1950
RWTPDGRLVF AGRADDQVKI RGFRVEPGEV EAVLAAHPAV AQATVAVRED
1960 1970 1980 1990 2000
TPGDKRLIGY LVPVEQGSAL TAAVRAYAAE RLPEYLVPAA FVELDAFPLT
2010 2020 2030 2040 2050
VNGKVDRAAL PAPRYLTGAG RLPADAREEL LCQVFAEVLG LPAVGVDDDF
2060 2070 2080 2090 2100
FTLGGHSLLV TRLVSRVRAT LDVELQIRTV FEAPTPGRLA ARLTETAVPG
2110 2120 2130 2140 2150
RKALVARTRP QRTPLSFAQQ RLWFLAQLEG PSPTYNLPLA LRLTGTLDRE
2160 2170 2180 2190 2200
AFLAALGDTV ARHEVLRTVF EVADDGTPYQ RVLPADATGF APEVVEVPSD
2210 2220 2230 2240 2250
GLADALARAA AYAFDLAVET PLRATLFAVA PDEHVLVLVV HHIAGDAWSM
2260 2270 2280 2290 2300
EPLARDVSTA YAARLVGDAP RWEPLPVQYA DYTLWQRELL GDEDDPDSLL
2310 2320 2330 2340 2350
SRQVSHWRDA LSGAPEELDL PADRPRPAEF SHRGRTAGLE FPAELHRRLR
2360 2370 2380 2390 2400
EVARAEGVTV FMVLQAALAV TLSRLGGGTD IPIGTAVAGR TDQALDELAG
2410 2420 2430 2440 2450
FFVNTLVLRT DLSGNPTFAE TLHRVRDDLL TALAHQDVPF ERLVEELAPV
2460 2470 2480 2490 2500
RSLTRHPLFQ VMLTLQNTAR AGGGASAALP GLETAVLPTG ATAAKFDLDL
2510 2520 2530 2540 2550
ALAETFDPEG APTGMHGTLV AAADLFDQET ADRLVACFTR ALEALTHRTD
2560 2570 2580 2590 2600
LRLGEVDLLD EAELSTLVED WNGPALPTSE ATLPELFAVQ AARTPDATAV
2610 2620 2630 2640 2650
TAGGVELSYA ELDARADRLA RGLVGRGVGP ESVVGVLLGR SADVVVAVLA
2660 2670 2680 2690 2700
VAKAGGAYLP VDPDYPADRV AFVLSDAGAE WVVTSAEFAP VLPAGVAAVP
2710 2720 2730 2740 2750
VDGAGSGPVF DSVPLPTVRP DHPAYVIYTS GSTGRPKGVV VPHRSVVALF
2760 2770 2780 2790 2800
AAAREMFAFG ADDVWSGFHS FAFDVSVWEM WGALLHGGRL VVVPFDVSRS
2810 2820 2830 2840 2850
PREFVELLER ERVTVLSQTP SAFYQLMGAG GALPDLHTVV FAGEALEPAR
2860 2870 2880 2890 2900
LDGWWERHGG TGPRLVNMYG ITETTVHVTH HDLRPDTAAD GSVIGRGLPG
2910 2920 2930 2940 2950
LSVFLLDEWL RPVPVGVTGE LYVAGAQAAR GYLGRAGLTG ERFVACPFGE
2960 2970 2980 2990 3000
AGGRMYRSGD RARWSRDGRL VFAGRADEQV KIRGFRIEPG EVEAVLAGHP
3010 3020 3030 3040 3050
DVAQAAVLVG DDTLGGRRLI GYVTPGGTTE DADGLADAVR VYAGERLPSY
3060 3070 3080 3090 3100
MVPSAFVVLD GLPLTVNGKL DRRALPAPAH TAGGGRAAAT VEEELLCQGF
3110 3120 3130 3140 3150
AEVLGLPAVG VDDDFFALGG HSLLAVSLVE WLRQRGVSVS VRALFVTPTP
3160 3170 3180 3190 3200
AGLAAVAAAP AVVVPPPGMI PEGATEITPE MLPLVDLTED EIARVTETVP
3210 3220 3230 3240 3250
GGAANVQDVY PLAPLQEGIF FHHLVADRDG TDVYVTPTVL DFDTRERLDD
3260 3270 3280 3290 3300
FLAGLQWVMD RHDIYRTAIV WEGLREPVQV VWRRAGLPVQ ERELDPAGPE
3310 3320 3330 3340 3350
AVEQLRTAAG GRIELDGAPL LRVDVAAAPE GGWLMLLRIH HLVQDHTSVE
3360 3370 3380 3390 3400
VLLDDLRAFL DGDADRLPAP VPFRDFVAQA RLGTPREEHE RYFAELLGDV
3410 3420 3430 3440 3450
TEPTAPYGLT DVRGDGEGSR HARLRVDDAL TGRMREVARS LGVSPASLFH
3460 3470 3480 3490 3500
LAWARVLGAV SGRDDVVFGT LLFGRMNAGA GADRAPGLFL NTLPVRVRMA
3510 3520 3530 3540 3550
GKSVTEALTE LRHQLADLMV HEHAPLTLAQ SATGLTGGGP LFTALFNYRH
3560 3570 3580 3590 3600
NREAPEPGEG IEGVRTVYTR EHTNYPLHVA VDNDGSSFDI TVNAVAPADP
3610 3620 3630 3640 3650
DEVCALLHTG LANLVTALAE APGTPLAGLG VLDERTRTRM RTEWNDTAVD
3660 3670 3680 3690 3700
VPDVTVPAAF SAQAARVPQA TALVCGDVEI GYAELDARAD RLARVLVEAG
3710 3720 3730 3740 3750
VAAESTVAVV MERSVDLVVT LLAVLKAGAV YVPLDAGWPV ARMRTVVEDS
3760 3770 3780 3790 3800
GARWVVVHEP TSGHEFLRGL GIPTLSADTD ADAEECVLPQ RWSPRQAAYV
3810 3820 3830 3840 3850
MYTSGSTGVP KGVVATHGDV VRLATDRCWG ATPRVLFHAP HAFDASTYEL
3860 3870 3880 3890 3900
WAPLLSGGTV VIAPNERVDP VVLRRLVTGH GLTHVHATAG LLRVLADQDP
3910 3920 3930 3940 3950
GCFTGVREVL TGGDVVPAES VRRVLDANPG VVVRQLYGPT EVTLCATQYE
3960 3970 3980 3990 4000
VADAAEVDGV LPIGRPLDNT RVYVLDGALN PVPVGVAGEL YVAGAGVARG
4010 4020 4030 4040 4050
YLGRPVLTGE RFVACPFETS GERRYRTGDL VRWDTEGRLV FLGRADEQVK
4060 4070 4080 4090 4100
IRGFRVEPGE VETVVTAHPA VAQATVLVRE DVPGDKRLVA YLVPADPGAA
4110 4120 4130 4140 4150
VGLTVRAYAA ERLPEYMLPS AMVELDALPL TPNGKVDRAA LPAPDYAAGA
4160 4170 4180 4190 4200
GRVPADAREE LLCQAFAAVL GLPAFGVDDD FFAKGGHSLL ATVLVGRIRA
4210 4220 4230 4240 4250
TFHVEMTIVA LFDAPTPASL ARWLVQARPG RIELAARERP ERVPLSFAQR
4260 4270 4280 4290 4300
RLWFLGQLEG PGATYNIPLL TRITGPLDRT AVDAALRDVL DRHEVLRTVY
4310 4320 4330 4340 4350
AVHGGEPHQR SRPVDTSGFA LPVVDVAPGG LTDALERAAG HEFDLSTDIP
4360 4370 4380 4390 4400
VRAWLFATAP EEHVLALVVH HIAADAWSMA PLTRDFAAAY AARRAGEEPD
4410 4420 4430 4440 4450
WTPLPVQYAD YALWQRDLLG DEGDPDSLIS QQVAYWRDTL DGAPEELRLP
4460 4470 4480 4490 4500
ADRPRPATVS YRGHLAPVEI PADVHGRLQQ VAREHGVTLF MTVQTALAVT
4510 4520 4530 4540 4550
LSRLGAGTDI PIGTTVAGRT DQALDDLIGF FVNTLVLRTR LGGDPTVTDV
4560 4570 4580 4590 4600
LRRVRETSLA AFTHQDVPFE KLVEELAPSR SLARHPLFQV MLTLQNAGTP
4610 4620 4630 4640 4650
GGGPSAVLPG LRTESLPTDD VAAKFDLDIT MGETFDAVGA PAGIQGMLVA
4660 4670 4680 4690 4700
AADLFDPATA ERIADSLVRV LKLIAEDTGT RLSAVDLLDA GERRRVVEEW
4710 4720 4730 4740 4750
NDTDAPPPAL SVPAAFEAQA ALTPDAVAVL GGDTRLTYAE LNARANRLAR
4760 4770 4780 4790 4800
LLVRHGVGPE SSVAVCLRRS AELPVALLAV LKAGGAYLPV DPGHPAERVG
4810 4820 4830 4840 4850
HVLDDARPAL LLTDRATAAD LPGPEHLVVD DPRTAAELQA LDTHDLTARE
4860 4870 4880 4890 4900
RLGALLPGHP AYVIHTSGST GRPKGVVVPH GAMANFVAAM RERFPMSSAD
4910 4920 4930 4940 4950
RLLAVTTVSF DIHVLELYVP LLAGAGVVVA EDADVRDPAA VAALIERFGV
4960 4970 4980 4990 5000
TVMQATPALW QALLTEHAGS ASGLRLLVGG EALPAALAAR MAAVGDTVTN
5010 5020 5030 5040 5050
LYGPTEVTVW ATAAGLTADD PDSRVPIGRP LPNTRAYVLD DALRPVPPGS
5060 5070 5080 5090 5100
PGELYLAGVQ LARGYLGRPA LSAERFTACP FASGERMYRT GDLVRWRTDG
5110 5120 5130 5140 5150
ALEFLERADD QVKIRGFRIE LGEVEAVLGA HPAVQRAAAA VREDTPGDRR
5160 5170 5180 5190 5200
LVGYAVADTP DPRALAEAVR AHAAERLPSY MVPSAVVVLD ALPLTANGKL
5210 5220 5230 5240 5250
DRKALPAPDF EAAAGSGRAP AGPREELLCA AFERVLGLER VGVDDDFFAL
5260 5270 5280 5290 5300
GGHSLLAVSL VEHLRERGVS VSVRALFQSA TPAGLAAASG AADQVTVPPN
5310 5320 5330 5340 5350
LIPPGATVIT PDMLTLADLT EAEIARVVDT VPGGAANIAD VYPLAPLQEG
5360 5370 5380 5390 5400
MFFHHLMAGG DDGDVYVLPT VLGFDSRDRL DAFLSALQQV VDRHDTYRTA
5410 5420 5430 5440 5450
FVWEGLREPV QVVWRNAALP VDEVVLDTAE DPAGQLLSGA GAWRTLNRAP
5460 5470 5480 5490 5500
LMRVRIAAEP GTGRWVALLL IHHLVQDHTA LDVLLHEVSA FLSGDAADLP
5510 5520 5530 5540 5550
EPVPFRGYVA QARLGTAREE HEAYFSGLLG DVTEPTAPYG LLDVHGDGGP
5560 5570 5580 5590 5600
ETRAQHWVDD ALAARVRGLA RSKGVSAATV FHLAWARVLG ALAGRDDVVF
5610 5620 5630 5640 5650
GTIVFGRMNS GTGSARVPGL FMNTLPVRVR LGAGAADAAL TDMRDQLAEL
5660 5670 5680 5690 5700
MAHEHAPLTL AQSVSGVQGG TPLFTSLFNY RFTAAPDTEP AAGEAGPLDG
5710 5720 5730 5740 5750
IGLLAYREQS EYPLTMSVDD AGERFLLTAD AHAPADPDQA CRLLHTCLES
5760 5770 5780 5790 5800
LVTTLEGAPH TGLAAVDVLD PDEHRRLLGV GSGAVVEVPG VSFPELFAAQ
5810 5820 5830 5840 5850
ARLSPDAVAL VGSGVELSYA EVEARANRLA RKLIGLGVGP ESVVALVLER
5860 5870 5880 5890 5900
SPELVIAVLA VLKAGGAYVA VDPGQPADRI RFVVEDASPV LVIDDVDFLT
5910 5920 5930 5940 5950
ETADFDAAPV SDADRLSPLL PSHPAYVIYT SGSTGRPKGV LISHAACVSY
5960 5970 5980 5990 6000
VASHVRYGVG EGSRVAQFAS AGFDAFCEEW WLALLGGGAL VVVPSERRLG
6010 6020 6030 6040 6050
EELVRFLLEE RVTHATLPPA VAVLMREEAL APGFVLDVGG EVCPPDLVDR
6060 6070 6080 6090 6100
WVAGGRTLFN SYGPSEATVN VTVWQAVDGS VGAGVPIGRP VGNTRVFVLD
6110 6120 6130 6140 6150
DGLRPVPVGV LGELYVSGVQ LGRGYLGRPG LTAERFVACP FDPGQRMYRT
6160 6170 6180 6190 6200
GDRVKWSADG ELVFAGRADD QVKIRGFRIE PGEVETVLAA HPAVAHAAVV
6210 6220 6230 6240 6250
VREDTPGDKR LTAYVVPAHD TDFADVPETL RAYAAEQLPA YMLPSAIVEL
6260 6270 6280 6290 6300
DVLPLTTNGK LDRKALPAPE YAAGAGRAAA DAREELLCGA FAQVLGLERV
6310 6320 6330 6340 6350
GVDDDFFALG GHSLLATRLV SRVRAVLDVE LPIRALFETP TPAALARGLA
6360 6370 6380 6390 6400
HAAPGRAALE PRERPARAPL SFAQRRLWFL GRLDGPNATY NIPLALRLTG
6410 6420 6430 6440 6450
ELDREALAGA FRDVMERHEV LRTVFATADG EPYQQVLPVD AAGFALRVAD
6460 6470 6480 6490 6500
VDVDGLDGAV TEAAGHAFDL SAEIPLRAWL FATAPEEHVL LMVVHHIAGD
6510 6520 6530 6540 6550
AWSMEPLARD MAAAYAARRE GREPGWAPLP VQYVDYALWQ RDVLDHEGDS
6560 6570 6580 6590 6600
GSVLSRQVAY WRDALAGAPE ELELPADRPR PAEVSTRGHQ APVLVPAEVH
6610 6620 6630 6640 6650
ERLLEVARGE GVTVFMVLQA AFATLLHRLG AGDDVPVGAS VAGRTDEGLN
6660 6670 6680 6690 6700
DLVGFFVNTL VIRTDLSGDP TFRELLGRVR AVSLSAYENQ DVPFERLVEE
6710 6720 6730 6740 6750
LAPARSLARH PLFQVMLTLQ NTGGPGGGPA VDLPGLRTDS LSAGSVAAKF
6760 6770 6780 6790 6800
DLDLSVGETL DATGAPAGIE GVLVAAADLF DPATVERIAG RLVRLLELVA
6810 6820 6830 6840 6850
GDTDMPLSAV DVLDADERRQ VVEEWNGTDA PLPARSVSDM FRAQAAVTPD
6860 6870 6880 6890 6900
AVAVLCGDDR LTYAELDARV NRLARLLIRR GVGPEARVAV CMERSADLLV
6910 6920 6930 6940 6950
ALLAVLRTGA AYLPVDPGHP AERVAFMLDE ARPALLLTGR GTAVEAFGPE
6960 6970 6980 6990 7000
RVVVDDPRTV AELADLDAGA VTDAERVTPP LPDHPAYVIY TSGSTGRPKG
7010 7020 7030 7040 7050
VVVTHGAMAN LVATMGRRFP MDTEDRLLAV TTVTFDIHVF ELYVPLLAGA
7060 7070 7080 7090 7100
AVVIAVDGDV RDPAAVAGLV ERFGASLMQG TPALWHGLLT AHAEAARGLR
7110 7120 7130 7140 7150
LLVAGEALSG SLAARMAAVG STVTNLYGPT EATVYATAAG VEAGTTASQV
7160 7170 7180 7190 7200
PIGRPIDNTR AYVLDGRLQP VPPGVSGELY LAGAQLARGY LERPGLSAER
7210 7220 7230 7240 7250
FVACPFGAAG ERMYRTGDVV RRRTDGQLEF RGRADDQVKI RGFRIEPGEV
7260 7270 7280 7290 7300
EAVLGAHPAV GRAAAVVRED VPGDKRLVAY VVAAGPDDGG PDDGGPDDGG
7310 7320 7330 7340 7350
LAAVAHDHAA EHLPSYMVPS AVVVVDALPL TSTGKLDRRA LPAPAYTAGG
7360 7370 7380 7390 7400
GRAAATVEEE LLCQGFAEVL GLPAVGVDDD FFALGGHSLL AVSLVEWLRQ
7410 7420 7430 7440 7450
RGLPVSVRAL FTTPTPAGLA AAAGPETVVV PPNLIPDDAT EITPEILTLV
7460 7470 7480 7490 7500
DLTEDEIARV TETVPGGAAN IQDVYPLAPL QEGILFHHLM LDRDATDVYV
7510 7520 7530 7540 7550
TPTVIGFDSR RRLDGFLEAM RWVLERHDVY RTAFVSDGLP EPVQVVLRHA
7560 7570 7580 7590 7600
GLPVEEVVLD PAGPDAEQQL AAAVRGRLDL HRAPLITTHV AADPRTGGRW
7610 7620 7630 7640 7650
LCLLRVHHLL QDHTGLQIML DELRAHLAGR TEHLPEPLPF RDFVAQARLG
7660 7670 7680 7690 7700
VPREQHRRHF TGLLGDVTEP TAPYGLVEVH GDGTAVAQAR LRVDGELTVR
7710 7720 7730 7740 7750
LKGVARSLGV SPATLFHLAW ARVLGAVSGR DDVVFGTIVF GRMNSGAGAD
7760 7770 7780 7790 7800
RVPGLFINTL PVRVRLAGAS VGEALTGLRH QLADLMVHEH APLALAQAAS
7810 7820 7830 7840 7850
GMPGGPLFTS LFNYRHNQDV PQETAGAMDG MGLLSDRDIT DYPLAVAIDV
7860 7870 7880 7890 7900
GGGGFTIAVD AVAPADPDQV CTLLRTCLDN LVTALEEAPD TPLRSLDVLG
7910 7920 7930 7940 7950
GAELSELVEG HNATSVARAD VSVPEAFARR TAADRDAVAL VSDSGEVTYG
7960 7970 7980 7990 8000
ELDARADELA RALVASGVGP ESVVAVLMER SADLVVALLA VLKAGGAYLP
8010 8020 8030 8040 8050
LDVRWPVARM RAVIEDAGAT SVVVHDATAG HDLGRTTGLD VIPVAAGADS
8060 8070 8080 8090 8100
AVVLPAAVAP GAAAYVMYTS GSTGVPKGVV ATHRDVVALA GDRCWGATPR
8110 8120 8130 8140 8150
VLFHAPHAFD ASTYELWVPL LSGGTVVLAP DEAVDGSVLR TLVTGHDLSH
8160 8170 8180 8190 8200
VHVTAGLLRV LADQDPGCFT GVREVLTGGD VVPAESVRRV LDANPGVVVR
8210 8220 8230 8240 8250
QLYGPTEVTL CATQYEVADA AEVDSVLPIG RPLDNTRVYV LDGSLNPVPV
8260 8270 8280 8290 8300
GVAGELYVAG AGVARGYLGR PVLTSERFVA CPFGVTGERM YRTGDLVRWD
8310 8320 8330 8340 8350
AEGRLVFMGR ADDQVKIRGF RVEPGEVETV VAAHPAVGQA AVVVREDTPG
8360 8370 8380 8390 8400
DKRLVAYLVP AGTETSFADA VRAHTADRLP EYLVPSAFVE LENLPLTVNG
8410 8420 8430 8440 8450
KLDREALPAP GFPHGAGDTV AHGPVAALEQ AMCEAFAEVL GLPSVGVDDD
8460 8470 8480 8490 8500
FFALGGHSLL AVRLVHRLRD RGVTTSVRDL MAAPTVTALR GTLGLSSVRD
8510 8520 8530 8540 8550
SLGVLLTIRG DGGRPPLFCV HPAGGLSWCY TPFAQHAPDD QPVYGLQARG
8560 8570 8580 8590 8600
VDGGAPFAGS LAEMAADYIE QLRQVQPAGP YHLVGYSFGA APAHEIAVQL
8610 8620 8630 8640 8650
REQGEEVAAL VIMDSFPLDR EIAATGAEDG AAPGGDLSWE GAIRAEFGHL
8660 8670 8680 8690 8700
LGGFTDEEIA VVARTFENNT RIRAAHTTGR FDGDALILTS ADSTTEDGPL
8710 8720 8730 8740 8750
TAKWAPHVLG ELTEVSIPCG HVDMVRPDMM GLAWQAISAW LKSPLTRGTE
8760 8770 8780 8790 8800
RTDMRRTSLL CVPFAGAGAS FFHPWAALTD GNPRIVALQL PGREWRLSEE
8810 8820 8830 8840 8850
PYRDVARAAA ELLPVVTEEI GPDDRVVIFG HSLGAVLAYE LAHLLVDRTG
8860 8870 8880 8890 8900
VDVARLFASG SPGPWTRRTR RATGLPDEEF LLRVKEFAGY DHEALSHPDM
8910 8920 8930 8940 8950
RELILPTLRA DVEMHENYVP AGDRPLPVPV TAVRGTRDDL VTAEQTGEWA
8960 8970 8980
RATSAGFTRA EVEGGHMYIA EDPGSLLRLV DDALAR
Length:8,986
Mass (Da):955,217
Last modified:October 31, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i392B300254B12FD0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
DQ403252 Genomic DNA Translation: ABD65958.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ403252 Genomic DNA Translation: ABD65958.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di1.10.1200.10, 5 hits
3.30.559.10, 8 hits
3.40.50.12780, 8 hits
3.40.50.1820, 4 hits
InterProiView protein in InterPro
IPR010071, AA_adenyl_domain
IPR029058, AB_hydrolase
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR020806, PKS_PP-bd
IPR020802, PKS_thioesterase
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
IPR001031, Thioesterase
PfamiView protein in Pfam
PF00501, AMP-binding, 8 hits
PF13193, AMP-binding_C, 8 hits
PF00668, Condensation, 8 hits
PF00550, PP-binding, 8 hits
PF00975, Thioesterase, 2 hits
SMARTiView protein in SMART
SM00823, PKS_PP, 8 hits
SM00824, PKS_TE, 1 hit
SUPFAMiSSF47336, SSF47336, 8 hits
SSF53474, SSF53474, 2 hits
TIGRFAMsiTIGR01733, AA-adenyl-dom, 8 hits
PROSITEiView protein in PROSITE
PS00455, AMP_BINDING, 8 hits
PS50075, CARRIER, 8 hits
PS00012, PHOSPHOPANTETHEINE, 3 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ06YZ1_9ACTN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q06YZ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: April 7, 2021
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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