UniProtKB - Q06796 (RL11_BACSU)
Protein
50S ribosomal protein L11
Gene
rplK
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.UniRule annotation
Miscellaneous
An unidentified mutation in this gene gives rise to thiostrepton resistance.
GO - Molecular functioni
- large ribosomal subunit rRNA binding Source: GO_Central
- structural constituent of ribosome Source: GO_Central
GO - Biological processi
- response to antibiotic Source: UniProtKB-KW
- translation Source: GO_Central
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Biological process | Antibiotic resistance |
Enzyme and pathway databases
BioCyci | BSUB:BSU01020-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L11UniRule annotationShort name: BL11 |
Gene namesi | Name:rplKUniRule annotation Synonyms:relC, tsp6 Ordered Locus Names:BSU01020 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
Subcellular locationi
Cytosol
- cytosolic large ribosomal subunit Source: GO_Central
Other locations
- large ribosomal subunit Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000104245 | 2 – 141 | 50S ribosomal protein L11Add BLAST | 140 |
Post-translational modificationi
One or more lysine residues are methylated.UniRule annotation
Keywords - PTMi
MethylationProteomic databases
jPOSTi | Q06796 |
PaxDbi | Q06796 |
PRIDEi | Q06796 |
Interactioni
Subunit structurei
Part of the ribosomal stalk of the 50S ribosomal subunit.
Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which 2 L12 dimers bind in a sequential fashion forming a pentameric L10(L12)2(L12)2 complex.
Protein-protein interaction databases
STRINGi | 224308.BSU01020 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL11 family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0080, Bacteria |
InParanoidi | Q06796 |
OMAi | CKQFNAK |
PhylomeDBi | Q06796 |
Family and domain databases
CDDi | cd00349, Ribosomal_L11, 1 hit |
Gene3Di | 1.10.10.250, 1 hit 3.30.1550.10, 1 hit |
HAMAPi | MF_00736, Ribosomal_L11, 1 hit |
InterProi | View protein in InterPro IPR000911, Ribosomal_L11/L12 IPR036796, Ribosomal_L11/L12_N_sf IPR006519, Ribosomal_L11_bac-typ IPR020783, Ribosomal_L11_C IPR036769, Ribosomal_L11_C_sf IPR020785, Ribosomal_L11_CS IPR020784, Ribosomal_L11_N |
PANTHERi | PTHR11661, PTHR11661, 1 hit |
Pfami | View protein in Pfam PF00298, Ribosomal_L11, 1 hit PF03946, Ribosomal_L11_N, 1 hit |
SMARTi | View protein in SMART SM00649, RL11, 1 hit |
SUPFAMi | SSF46906, SSF46906, 1 hit SSF54747, SSF54747, 1 hit |
TIGRFAMsi | TIGR01632, L11_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00359, RIBOSOMAL_L11, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q06796-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKKVVKVVK LQIPAGKANP APPVGPALGQ AGVNIMGFCK EFNARTADQA
60 70 80 90 100
GLIIPVEISV YEDRSFTFIT KTPPAAVLLK KAAGIESGSG EPNRNKVATV
110 120 130 140
KRDKVREIAE TKMPDLNAAD VEAAMRMVEG TARSMGIVIE D
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 35 | I → V in BAA02561 (PubMed:7968510).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D13303 Genomic DNA Translation: BAA02561.1 AL009126 Genomic DNA Translation: CAB11878.2 |
PIRi | S39860 |
RefSeqi | NP_387983.2, NC_000964.3 WP_003156430.1, NZ_JNCM01000029.1 |
Genome annotation databases
EnsemblBacteriai | CAB11878; CAB11878; BSU_01020 |
GeneIDi | 56456378 936838 |
KEGGi | bsu:BSU01020 |
PATRICi | fig|224308.179.peg.105 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D13303 Genomic DNA Translation: BAA02561.1 AL009126 Genomic DNA Translation: CAB11878.2 |
PIRi | S39860 |
RefSeqi | NP_387983.2, NC_000964.3 WP_003156430.1, NZ_JNCM01000029.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3J3V | electron microscopy | 13.30 | 6 | 1-141 | [»] | |
3J3W | electron microscopy | 10.70 | 6 | 1-141 | [»] | |
3J9W | electron microscopy | 3.90 | BK | 1-141 | [»] | |
7AQC | electron microscopy | 2.99 | I | 1-141 | [»] | |
7AQD | electron microscopy | 3.10 | I | 1-141 | [»] | |
7AS8 | electron microscopy | 2.90 | K | 1-141 | [»] | |
7AS9 | electron microscopy | 3.50 | K | 1-141 | [»] | |
7ASA | electron microscopy | 3.50 | K | 1-141 | [»] | |
SMRi | Q06796 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 224308.BSU01020 |
Proteomic databases
jPOSTi | Q06796 |
PaxDbi | Q06796 |
PRIDEi | Q06796 |
Genome annotation databases
EnsemblBacteriai | CAB11878; CAB11878; BSU_01020 |
GeneIDi | 56456378 936838 |
KEGGi | bsu:BSU01020 |
PATRICi | fig|224308.179.peg.105 |
Phylogenomic databases
eggNOGi | COG0080, Bacteria |
InParanoidi | Q06796 |
OMAi | CKQFNAK |
PhylomeDBi | Q06796 |
Enzyme and pathway databases
BioCyci | BSUB:BSU01020-MONOMER |
Miscellaneous databases
PROi | PR:Q06796 |
Family and domain databases
CDDi | cd00349, Ribosomal_L11, 1 hit |
Gene3Di | 1.10.10.250, 1 hit 3.30.1550.10, 1 hit |
HAMAPi | MF_00736, Ribosomal_L11, 1 hit |
InterProi | View protein in InterPro IPR000911, Ribosomal_L11/L12 IPR036796, Ribosomal_L11/L12_N_sf IPR006519, Ribosomal_L11_bac-typ IPR020783, Ribosomal_L11_C IPR036769, Ribosomal_L11_C_sf IPR020785, Ribosomal_L11_CS IPR020784, Ribosomal_L11_N |
PANTHERi | PTHR11661, PTHR11661, 1 hit |
Pfami | View protein in Pfam PF00298, Ribosomal_L11, 1 hit PF03946, Ribosomal_L11_N, 1 hit |
SMARTi | View protein in SMART SM00649, RL11, 1 hit |
SUPFAMi | SSF46906, SSF46906, 1 hit SSF54747, SSF54747, 1 hit |
TIGRFAMsi | TIGR01632, L11_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00359, RIBOSOMAL_L11, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL11_BACSU | |
Accessioni | Q06796Primary (citable) accession number: Q06796 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 1, 1994 |
Last sequence update: | June 16, 2009 | |
Last modified: | April 7, 2021 | |
This is version 131 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families