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UniProtKB - Q06795 (NUSG_BACSU)

Entry version 130 (29 Sep 2021)
Sequence version 1 (01 Jun 1994)
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Protein

Transcription termination/antitermination protein NusG

Gene

nusG

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Participates in transcription elongation, termination and antitermination. Stimulates RNA polymerase pausing at U107 and U144 in the trp leader. NusG-stimulated pausing is sequence specific. Does not affect trp leader termination.

UniRule annotation2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription antitermination, Transcription regulation, Transcription termination

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		BSUB:BSU01010-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription termination/antitermination protein NusGUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:nusGUniRule annotation
Ordered Locus Names:BSU01010
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus subtilis (strain 168)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224308 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001570 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001139161 – 177Transcription termination/antitermination protein NusGAdd BLAST177

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q06795

PRoteomics IDEntifications database

More...PRIDEi		Q06795

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		224308.BSU01010

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q06795

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini128 – 156KOWUniRule annotationAdd BLAST29

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NusG family.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG0250, Bacteria

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q06795

Identification of Orthologs from Complete Genome Data

More...OMAi		DGPFNGF

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q06795

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.30.30.30, 1 hit
3.30.70.940, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_00948, NusG, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR005824, KOW
IPR006645, NGN_dom
IPR036735, NGN_dom_sf
IPR043425, NusG-like
IPR014722, Rib_L2_dom2
IPR001062, Transcrpt_antiterm_NusG
IPR015869, Transcrpt_antiterm_NusG_bac_CS
IPR008991, Translation_prot_SH3-like_sf

The PANTHER Classification System

More...PANTHERi		PTHR30265, PTHR30265, 1 hit
PTHR30265:SF2, PTHR30265:SF2, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00467, KOW, 1 hit
PF02357, NusG, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00338, NUSGTNSCPFCT

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00739, KOW, 1 hit
SM00738, NGN, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50104, SSF50104, 1 hit
SSF82679, SSF82679, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00922, nusG, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01014, NUSG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q06795-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKNWYVVHT YSGYENKVKA NLEKRVESMG MQDKIFRVVV PEEEETDIKN 
        60         70         80         90        100
GKKKVVKKKV FPGYVLVEIV MTDDSWYVVR NTPGVTGFVG SAGSGSKPTP 
       110        120        130        140        150
LLPGEAETIL KRMGMDERKT DIDFELKETV KVIDGPFANF TGSIEEIDYD 
       160        170 
KSKVKVFVNM FGRETPVELE FTQIDKL
Length:177
Mass (Da):20,126
Last modified:June 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC9F2557AC35262EF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
D13303 Genomic DNA Translation: BAA02560.1
AL009126 Genomic DNA Translation: CAB11877.1

Protein sequence database of the Protein Information Resource

More...PIRi		S39859

NCBI Reference Sequences

More...RefSeqi		NP_387982.1, NC_000964.3
WP_003225764.1, NZ_JNCM01000029.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		CAB11877; CAB11877; BSU_01010

Database of genes from NCBI RefSeq genomes

More...GeneIDi		64301939
936851

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		bsu:BSU01010

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|224308.179.peg.104

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13303 Genomic DNA Translation: BAA02560.1
AL009126 Genomic DNA Translation: CAB11877.1
PIRiS39859
RefSeqiNP_387982.1, NC_000964.3
WP_003225764.1, NZ_JNCM01000029.1

3D structure databases

SMRiQ06795
ModBaseiSearch...

Protein-protein interaction databases

STRINGi224308.BSU01010

Proteomic databases

PaxDbiQ06795
PRIDEiQ06795

Genome annotation databases

EnsemblBacteriaiCAB11877; CAB11877; BSU_01010
GeneIDi64301939
936851
KEGGibsu:BSU01010
PATRICifig|224308.179.peg.104

Phylogenomic databases

eggNOGiCOG0250, Bacteria
InParanoidiQ06795
OMAiDGPFNGF
PhylomeDBiQ06795

Enzyme and pathway databases

BioCyciBSUB:BSU01010-MONOMER

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q06795

Family and domain databases

Gene3Di2.30.30.30, 1 hit
3.30.70.940, 1 hit
HAMAPiMF_00948, NusG, 1 hit
InterProiView protein in InterPro
IPR005824, KOW
IPR006645, NGN_dom
IPR036735, NGN_dom_sf
IPR043425, NusG-like
IPR014722, Rib_L2_dom2
IPR001062, Transcrpt_antiterm_NusG
IPR015869, Transcrpt_antiterm_NusG_bac_CS
IPR008991, Translation_prot_SH3-like_sf
PANTHERiPTHR30265, PTHR30265, 1 hit
PTHR30265:SF2, PTHR30265:SF2, 1 hit
PfamiView protein in Pfam
PF00467, KOW, 1 hit
PF02357, NusG, 1 hit
PRINTSiPR00338, NUSGTNSCPFCT
SMARTiView protein in SMART
SM00739, KOW, 1 hit
SM00738, NGN, 1 hit
SUPFAMiSSF50104, SSF50104, 1 hit
SSF82679, SSF82679, 1 hit
TIGRFAMsiTIGR00922, nusG, 1 hit
PROSITEiView protein in PROSITE
PS01014, NUSG, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNUSG_BACSU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q06795
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: September 29, 2021
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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