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Protein

Condensin complex subunit 3

Gene

YCG1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase.

Miscellaneous

Present with 1920 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • chromatin binding Source: SGD

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, DNA condensation, Mitosis

Enzyme and pathway databases

BioCyciYEAST:G3O-29882-MONOMER
ReactomeiR-SCE-2514853 Condensation of Prometaphase Chromosomes

Names & Taxonomyi

Protein namesi
Recommended name:
Condensin complex subunit 3
Alternative name(s):
CAPG homolog
Gene namesi
Name:YCG1
Synonyms:YCS5
Ordered Locus Names:YDR325W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR325W
SGDiS000002733 YCG1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000950481 – 1035Condensin complex subunit 3Add BLAST1035

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei198PhosphoserineCombined sources1
Modified residuei933PhosphoserineCombined sources1
Modified residuei981PhosphoserineCombined sources1
Modified residuei1008PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ06680
PaxDbiQ06680
PRIDEiQ06680

PTM databases

iPTMnetiQ06680

Interactioni

Subunit structurei

Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: BRN1, YCS4 and YCG1/YCS5.1 Publication

Binary interactionsi

Protein-protein interaction databases

BioGridi32383, 218 interactors
ComplexPortaliCPX-1869 Nuclear condensin complex
IntActiQ06680, 6 interactors
MINTiQ06680
STRINGi4932.YDR325W

Structurei

Secondary structure

11035
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ06680
SMRiQ06680
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati113 – 150HEAT 1Add BLAST38
Repeati153 – 191HEAT 2Add BLAST39
Repeati201 – 239HEAT 3Add BLAST39
Repeati597 – 635HEAT 4Add BLAST39
Repeati827 – 864HEAT 5Add BLAST38

Sequence similaritiesi

Belongs to the CND3 (condensin subunit 3) family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

GeneTreeiENSGT00390000001577
HOGENOMiHOG000001059
InParanoidiQ06680
KOiK06678
OMAiTNQECFE
OrthoDBiEOG092C0M39

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR027165 CND3
IPR025977 Cnd3_C
PANTHERiPTHR14418 PTHR14418, 1 hit
PfamiView protein in Pfam
PF12719 Cnd3, 1 hit
SUPFAMiSSF48371 SSF48371, 3 hits

Sequencei

Sequence statusi: Complete.

Q06680-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQDPDGIDIN TKIFNSVAEV FQKAQGSYAG HRKHIAVLKK IQSKAVEQGY
60 70 80 90 100
EDAFNFWFDK LVTKILPLKK NEIIGDRIVK LVAAFIASLE RELILAKKQN
110 120 130 140 150
YKLTNDEEGI FSRFVDQFIR HVLRGVESPD KNVRFRVLQL LAVIMDNIGE
160 170 180 190 200
IDESLFNLLI LSLNKRIYDR EPTVRIQAVF CLTKFQDEEQ TEHLTELSDN
210 220 230 240 250
EENFEATRTL VASIQNDPSA EVRRAAMLNL INDNNTRPYI LERARDVNIV
260 270 280 290 300
NRRLVYSRIL KSMGRKCFDD IEPHIFDQLI EWGLEDRELS VRNACKRLIA
310 320 330 340 350
HDWLNALDGD LIELLEKLDV SRSSVCVKAI EALFQSRPDI LSKIKFPESI
360 370 380 390 400
WKDFTVEIAF LFRAIYLYCL DNNITEMLEE NFPEASKLSE HLNHYILLRY
410 420 430 440 450
HHNDISNDSQ SHFDYNTLEF IIEQLSIAAE RYDYSDEVGR RSMLTVVRNM
460 470 480 490 500
LALTTLSEPL IKIGIRVMKS LSINEKDFVT MAIEIINDIR DDDIEKQEQE
510 520 530 540 550
EKIKSKKINR RNETSVDEED ENGTHNDEVN EDEEDDNISS FHSAVENLVQ
560 570 580 590 600
GNGNVSESDI INNLPPEKEA SSATIVLCLT RSSYMLELVN TPLTENILIA
610 620 630 640 650
SLMDTLITPA VRNTAPNIRE LGVKNLGLCC LLDVKLAIDN MYILGMCVSK
660 670 680 690 700
GNASLKYIAL QVIVDIFSVH GNTVVDGEGK VDSISLHKIF YKVLKNNGLP
710 720 730 740 750
ECQVIAAEGL CKLFLADVFT DDDLFETLVL SYFSPINSSN EALVQAFAFC
760 770 780 790 800
IPVYCFSHPA HQQRMSRTAA DILLRLCVLW DDLQSSVIPE VDREAMLKPN
810 820 830 840 850
IIFQQLLFWT DPRNLVNQTG STKKDTVQLT FLIDVLKIYA QIEKKEIKKM
860 870 880 890 900
IITNINAIFL SSEQDYSTLK ELLEYSDDIA ENDNLDNVSK NALDKLRNNL
910 920 930 940 950
NSLIEEINER SETQTKDENN TANDQYSSIL GNSFNKSSND TIEHAADITD
960 970 980 990 1000
GNNTELTKTT VNISAVDNTT EQSNSRKRTR SEAEQIDTSK NLENMSIQDT
1010 1020 1030
STVAKNVSFV LPDEKSDAMS IDEEDKDSES FSEVC
Length:1,035
Mass (Da):117,851
Last modified:March 1, 2003 - v2
Checksum:iD3EF17EDFA769FF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U32517 Genomic DNA Translation: AAB64761.2
BK006938 Genomic DNA Translation: DAA12168.1
RefSeqiNP_010612.2, NM_001180633.1

Genome annotation databases

EnsemblFungiiYDR325W; YDR325W; YDR325W
GeneIDi851925
KEGGisce:YDR325W

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U32517 Genomic DNA Translation: AAB64761.2
BK006938 Genomic DNA Translation: DAA12168.1
RefSeqiNP_010612.2, NM_001180633.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5OQNX-ray3.15A6-932[»]
5OQOX-ray3.25A6-932[»]
5OQPX-ray2.98A6-932[»]
5OQQX-ray2.79A/B6-932[»]
ProteinModelPortaliQ06680
SMRiQ06680
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32383, 218 interactors
ComplexPortaliCPX-1869 Nuclear condensin complex
IntActiQ06680, 6 interactors
MINTiQ06680
STRINGi4932.YDR325W

PTM databases

iPTMnetiQ06680

Proteomic databases

MaxQBiQ06680
PaxDbiQ06680
PRIDEiQ06680

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR325W; YDR325W; YDR325W
GeneIDi851925
KEGGisce:YDR325W

Organism-specific databases

EuPathDBiFungiDB:YDR325W
SGDiS000002733 YCG1

Phylogenomic databases

GeneTreeiENSGT00390000001577
HOGENOMiHOG000001059
InParanoidiQ06680
KOiK06678
OMAiTNQECFE
OrthoDBiEOG092C0M39

Enzyme and pathway databases

BioCyciYEAST:G3O-29882-MONOMER
ReactomeiR-SCE-2514853 Condensation of Prometaphase Chromosomes

Miscellaneous databases

PROiPR:Q06680

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR027165 CND3
IPR025977 Cnd3_C
PANTHERiPTHR14418 PTHR14418, 1 hit
PfamiView protein in Pfam
PF12719 Cnd3, 1 hit
SUPFAMiSSF48371 SSF48371, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiCND3_YEAST
AccessioniPrimary (citable) accession number: Q06680
Secondary accession number(s): D6VSV8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 152 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names
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Main funding by: National Institutes of Health

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