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UniProtKB - Q06598 (ARR3_YEAST)

Entry version 160 (10 Feb 2021)
Sequence version 1 (01 Nov 1996)
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Protein

Arsenical-resistance protein 3

Gene

ARR3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plasma membrane transporter that confers resistance to toxic metalloids by mediating extrusion of arsenite (As(III)) and antimonite (Sb(III)) out of cells. Displays low-affinity As(III)/H+ and Sb(III)/H+ exchange activity.8 Publications

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

Vmax for arsenite is approximately 3 times higher than for antimonite.1 Publication
  1. KM=2 mM for arsenite export1 Publication
  2. KM=2 mM for antimonite export1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    Complete GO annotation on QuickGO ...

    GO - Biological processi

    Complete GO annotation on QuickGO ...

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Biological processAntiport, Arsenical resistance, Ion transport, Transport

    Protein family/group databases

    Transport Classification Database

    More...    TCDBi    		2.A.59.1.1, the arsenical resistance-3 (acr3) family

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Arsenical-resistance protein 3Curated
    Alternative name(s):
    Arsenic compounds resistance protein 31 Publication
    As(III)/H(+) and Sb(III)/H(+)antiporterCurated
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:ARR3Imported
    Synonyms:ACR31 Publication
    Ordered Locus Names:YPR201WImported
    ORF Names:P9677.2
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XVI

    Organism-specific databases

    Saccharomyces Genome Database

    More...    SGDi    		S000006405, ARR3

    Eukaryotic Pathogen, Vector and Host Database Resources

    More...    VEuPathDBi    		FungiDB:YPR201W

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 34Cytoplasmic1 PublicationAdd BLAST34
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
    Topological domaini56 – 69Extracellular1 PublicationAdd BLAST14
    Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
    Topological domaini91 – 113Cytoplasmic1 PublicationAdd BLAST23
    Transmembranei114 – 134HelicalSequence analysisAdd BLAST21
    Topological domaini135 – 141Extracellular1 Publication7
    Transmembranei142 – 162HelicalSequence analysisAdd BLAST21
    Topological domaini163 – 169Cytoplasmic1 Publication7
    Transmembranei170 – 190HelicalSequence analysisAdd BLAST21
    Topological domaini191 – 216Extracellular1 PublicationAdd BLAST26
    Transmembranei217 – 237HelicalSequence analysisAdd BLAST21
    Topological domaini238 – 245Cytoplasmic1 Publication8
    Transmembranei246 – 266HelicalSequence analysisAdd BLAST21
    Topological domaini267 – 280Extracellular1 PublicationAdd BLAST14
    Transmembranei281 – 301HelicalSequence analysisAdd BLAST21
    Topological domaini302 – 343Cytoplasmic1 PublicationAdd BLAST42
    Transmembranei344 – 364HelicalSequence analysisAdd BLAST21
    Topological domaini365 – 369Extracellular1 Publication5
    Transmembranei370 – 390HelicalSequence analysisAdd BLAST21
    Topological domaini391 – 404Cytoplasmic1 PublicationAdd BLAST14

    Keywords - Cellular componenti

    Cell membrane, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    <p>This subsection of the 'Pathology and Biotech' section describes the use of a specific protein in the biotechnological industry.<p><a href='/help/biotechnological_use' target='_top'>More...</a></p>Biotechnological usei

    Heterologous expression endows plants with greater arsenic resistance by enhancing arsenite efflux. Reduces arsenic accumulation in rice grains (PubMed:22107880). Does not lower significantly arsenic tissue levels in Arabidopsis (PubMed:22380876).2 Publications

    <p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

    Leads to sensitivity to antimony, tellurite, cadmium, and phenylarsine oxide.1 Publication

    Mutagenesis

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi90C → A: Leads to ER retention and arsenite sensitivity. 1 Publication1
    Mutagenesisi117N → A: Impairs cell membrane localization, and leads to arsenite sensitivity. 1 Publication1
    Mutagenesisi150R → A: Leads to ER retention, protein unstability and arsenite sensitivity. 1 Publication1
    Mutagenesisi151C → V: Leads to complete loss of metalloid transport function. 1 Publication1
    Mutagenesisi158W → A: Impairs cell membrane localization, and leads to arsenite sensitivity. 1 Publication1
    Mutagenesisi169C → A: Greatly reduces arsenite efflux. 1 Publication1
    Mutagenesisi176N → A: Leads to ER retention, protein unstability and arsenite sensitivity. 1 Publication1
    Mutagenesisi192C → A: Results in moderate reduction of arsenite transport capacities and sorting perturbations. 1 Publication1
    Mutagenesisi230R → A: Leads to ER retention, protein unstability and arsenite sensitivity. 1 Publication1
    Mutagenesisi266F → A: Impairs arsenite resistance. 1 Publication1
    Mutagenesisi283C → A: Does not alter the arsenite/proton exchange across the plasma membrane. 1 Publication1
    Mutagenesisi290Y → A: Leads to ER retention, protein unstability and arsenite sensitivity. 1 Publication1
    Mutagenesisi316C → A: Results in moderate reduction of arsenite transport capacities and sorting perturbations. 1 Publication1
    Mutagenesisi318C → A: Results in moderate reduction of arsenite transport capacities and sorting perturbations. 1 Publication1
    Mutagenesisi333C → A: Results in moderate reduction of arsenite transport capacities and sorting perturbations. 1 Publication1
    Mutagenesisi344C → A: Results in moderate reduction of arsenite transport capacities and sorting perturbations. 1 Publication1
    Mutagenesisi345F → A: Leads to ER retention, protein unstability and arsenite sensitivity. 1 Publication1
    Mutagenesisi349S → A: Impairs arsenite resistance. 1 Publication1
    Mutagenesisi351N → A: Leads to ER retention, protein unstability and arsenite sensitivity. 1 Publication1
    Mutagenesisi352F → A: Impairs arsenite resistance. 1 Publication1
    Mutagenesisi353E → A: Impairs arsenite resistance. 1 Publication1
    Mutagenesisi380E → A: Impairs arsenite resistance. 1 Publication1

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000644401 – 404Arsenical-resistance protein 3Add BLAST404

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi201N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
    Glycosylationi365N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...    PaxDbi    		Q06598

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...    iPTMneti    		Q06598

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

    Expression is highly induced by arsenite and antimonite.1 Publication

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGRID)

    More...    BioGRIDi    		36371, 91 interactors

    Database of interacting proteins

    More...    DIPi    		DIP-3797N

    Protein interaction database and analysis system

    More...    IntActi    		Q06598, 3 interactors

    Molecular INTeraction database

    More...    MINTi    		Q06598

    STRING: functional protein association networks

    More...    STRINGi    		4932.YPR201W

    Miscellaneous databases

    RNAct, Protein-RNA interaction predictions for model organisms.

    More...    RNActi    		Q06598, protein

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family. [View classification]Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...    eggNOGi    		ENOG502QPKH, Eukaryota

    Ensembl GeneTree

    More...    GeneTreei    		ENSGT00950000182808

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...    HOGENOMi    		CLU_022869_0_0_1

    InParanoid: Eukaryotic Ortholog Groups

    More...    InParanoidi    		Q06598

    Identification of Orthologs from Complete Genome Data

    More...    OMAi    		CTAMVLM

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...    InterProi    		View protein in InterPro
    IPR004706, Arsenical-R_Acr3
    IPR002657, BilAc:Na_symport/Acr3

    The PANTHER Classification System

    More...    PANTHERi    		PTHR43057, PTHR43057, 1 hit

    Pfam protein domain database

    More...    Pfami    		View protein in Pfam
    PF01758, SBF, 1 hit

    PIRSF; a whole-protein classification database

    More...    PIRSFi    		PIRSF005508, Acr3, 1 hit

    TIGRFAMs; a protein family database

    More...    TIGRFAMsi    		TIGR00832, acr3, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    Q06598-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MSEDQKSENS VPSKVNMVNR TDILTTIKSL SWLDLMLPFT IILSIIIAVI 
            60         70         80         90        100
    ISVYVPSSRH TFDAEGHPNL MGVSIPLTVG MIVMMIPPIC KVSWESIHKY 
           110        120        130        140        150
    FYRSYIRKQL ALSLFLNWVI GPLLMTALAW MALFDYKEYR QGIIMIGVAR 
           160        170        180        190        200
    CIAMVLIWNQ IAGGDNDLCV VLVITNSLLQ MVLYAPLQIF YCYVISHDHL 
           210        220        230        240        250
    NTSNRVLFEE VAKSVGVFLG IPLGIGIIIR LGSLTIAGKS NYEKYILRFI 
           260        270        280        290        300
    SPWAMIGFHY TLFVIFISRG YQFIHEIGSA ILCFVPLVLY FFIAWFLTFA 
           310        320        330        340        350
    LMRYLSISRS DTQRECSCDQ ELLLKRVWGR KSCEASFSIT MTQCFTMASN 
           360        370        380        390        400
    NFELSLAIAI SLYGNNSKQA IAATFGPLLE VPILLILAIV ARILKPYYIW 

    NNRN
    Length:404
    Mass (Da):45,848
    Last modified:November 1, 1996 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1BE290E26772B4CA
    GO

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...    EMBLi

    GenBank nucleotide sequence database

    More...    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...    DDBJi
    Links Updated
    		U25841 Genomic DNA Translation: AAB64629.1
    BK006949 Genomic DNA Translation: DAA11615.1

    Protein sequence database of the Protein Information Resource

    More...    PIRi    		S58830

    NCBI Reference Sequences

    More...    RefSeqi    		NP_015527.1, NM_001184298.1

    Genome annotation databases

    Ensembl fungal genome annotation project

    More...    EnsemblFungii    		YPR201W_mRNA; YPR201W; YPR201W

    Database of genes from NCBI RefSeq genomes

    More...    GeneIDi    		856331

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...    KEGGi    		sce:YPR201W

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    		U25841 Genomic DNA Translation: AAB64629.1
    BK006949 Genomic DNA Translation: DAA11615.1
    PIRiS58830
    RefSeqiNP_015527.1, NM_001184298.1

    3D structure databases

    Database of comparative protein structure models

    More...    ModBasei    		Search...

    SWISS-MODEL Interactive Workspace

    More...    SWISS-MODEL-Workspacei    		Submit a new modelling project...

    Protein-protein interaction databases

    BioGRIDi36371, 91 interactors
    DIPiDIP-3797N
    IntActiQ06598, 3 interactors
    MINTiQ06598
    STRINGi4932.YPR201W

    Protein family/group databases

    TCDBi2.A.59.1.1, the arsenical resistance-3 (acr3) family

    PTM databases

    iPTMnetiQ06598

    Proteomic databases

    PaxDbiQ06598

    Genome annotation databases

    EnsemblFungiiYPR201W_mRNA; YPR201W; YPR201W
    GeneIDi856331
    KEGGisce:YPR201W

    Organism-specific databases

    SGDiS000006405, ARR3
    VEuPathDBiFungiDB:YPR201W

    Phylogenomic databases

    eggNOGiENOG502QPKH, Eukaryota
    GeneTreeiENSGT00950000182808
    HOGENOMiCLU_022869_0_0_1
    InParanoidiQ06598
    OMAiCTAMVLM

    Miscellaneous databases

    Protein Ontology

    More...    PROi    		PR:Q06598
    RNActiQ06598, protein

    Family and domain databases

    InterProiView protein in InterPro
    IPR004706, Arsenical-R_Acr3
    IPR002657, BilAc:Na_symport/Acr3
    PANTHERiPTHR43057, PTHR43057, 1 hit
    PfamiView protein in Pfam
    PF01758, SBF, 1 hit
    PIRSFiPIRSF005508, Acr3, 1 hit
    TIGRFAMsiTIGR00832, acr3, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...    ProtoNeti    		Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...    MobiDBi    		Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARR3_YEAST
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q06598
    Secondary accession number(s): D6W4J9
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: February 10, 2021
    This is version 160 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome XVI
      Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families
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