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UniProtKB - Q06553 (PRTR_PSEAE)
Protein
HTH-type transcriptional regulator PrtR
Gene
prtR
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Functioni
Represses the promoter activity of the prtN gene.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 27 – 46 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 20 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
GO - Biological processi
- bacteriocin biosynthetic process Source: UniProtKB-KW
- negative regulation of secondary metabolite biosynthetic process Source: PseudoCAP
Keywordsi
Molecular function | DNA-binding, Repressor |
Biological process | Antibiotic biosynthesis, Bacteriocin biosynthesis, Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: HTH-type transcriptional regulator PrtRAlternative name(s): Pyocin repressor protein |
Gene namesi | Name:prtR Ordered Locus Names:PA0611 |
Organismi | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Taxonomic identifieri | 208964 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Organism-specific databases
PseudoCAPi | PA0611 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000149730 | 1 – 256 | HTH-type transcriptional regulator PrtRAdd BLAST | 256 |
Proteomic databases
PaxDbi | Q06553 |
Expressioni
Inductioni
Inactivated by the activated RecA protein after UV irradiation.
Structurei
3D structure databases
AlphaFoldDBi | Q06553 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 69 | HTH cro/C1-typePROSITE-ProRule annotationAdd BLAST | 54 |
Phylogenomic databases
HOGENOMi | CLU_066192_1_4_6 |
InParanoidi | Q06553 |
OMAi | HVNNWFK |
PhylomeDBi | Q06553 |
Family and domain databases
CDDi | cd00093, HTH_XRE, 1 hit cd06529, S24_LexA-like, 1 hit |
Gene3Di | 1.10.260.40, 1 hit |
InterProi | View protein in InterPro IPR001387, Cro/C1-type_HTH IPR010982, Lambda_DNA-bd_dom_sf IPR039418, LexA-like IPR036286, LexA/Signal_pep-like_sf IPR015927, Peptidase_S24_S26A/B/C |
Pfami | View protein in Pfam PF01381, HTH_3, 1 hit PF00717, Peptidase_S24, 1 hit |
SMARTi | View protein in SMART SM00530, HTH_XRE, 1 hit |
SUPFAMi | SSF47413, SSF47413, 1 hit SSF51306, SSF51306, 1 hit |
PROSITEi | View protein in PROSITE PS50943, HTH_CROC1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q06553-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDKSTQIPPD SFAARLKQAM AMRNLKQETL AEAAGVSQNT IHKLTSGKAQ
60 70 80 90 100
STRKLIEIAA ALGVSPVWLQ TGEGAPAARS AVSVADGSPL VLEPLHPWDS
110 120 130 140 150
DTPLDEDEVE LPLYKEVEMS AGAGRTAVRE IEGRKLRFSY ATLRASGVDP
160 170 180 190 200
SAAICAQLTG NSMEPLIMDG STIGVDTATT HITDGEIYAL EHDGMLRVKF
210 220 230 240 250
VYRLPGGGIR LRSFNREEYP DEEYSPEDMR SRQISMIGWV FWWSTVRHRR
GPSLVR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D12706 Genomic DNA Translation: BAA02198.1 AB030825 Genomic DNA Translation: BAA83146.1 AB030826 Genomic DNA Translation: BAA83132.1 AE004091 Genomic DNA Translation: AAG04000.1 |
PIRi | A47062 |
RefSeqi | NP_249302.1, NC_002516.2 WP_003113202.1, NZ_QZGE01000010.1 |
Genome annotation databases
EnsemblBacteriai | AAG04000; AAG04000; PA0611 |
GeneIDi | 879679 |
KEGGi | pae:PA0611 |
PATRICi | fig|208964.12.peg.647 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D12706 Genomic DNA Translation: BAA02198.1 AB030825 Genomic DNA Translation: BAA83146.1 AB030826 Genomic DNA Translation: BAA83132.1 AE004091 Genomic DNA Translation: AAG04000.1 |
PIRi | A47062 |
RefSeqi | NP_249302.1, NC_002516.2 WP_003113202.1, NZ_QZGE01000010.1 |
3D structure databases
AlphaFoldDBi | Q06553 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 287.DR97_3580 |
Proteomic databases
PaxDbi | Q06553 |
Genome annotation databases
EnsemblBacteriai | AAG04000; AAG04000; PA0611 |
GeneIDi | 879679 |
KEGGi | pae:PA0611 |
PATRICi | fig|208964.12.peg.647 |
Organism-specific databases
PseudoCAPi | PA0611 |
Phylogenomic databases
HOGENOMi | CLU_066192_1_4_6 |
InParanoidi | Q06553 |
OMAi | HVNNWFK |
PhylomeDBi | Q06553 |
Family and domain databases
CDDi | cd00093, HTH_XRE, 1 hit cd06529, S24_LexA-like, 1 hit |
Gene3Di | 1.10.260.40, 1 hit |
InterProi | View protein in InterPro IPR001387, Cro/C1-type_HTH IPR010982, Lambda_DNA-bd_dom_sf IPR039418, LexA-like IPR036286, LexA/Signal_pep-like_sf IPR015927, Peptidase_S24_S26A/B/C |
Pfami | View protein in Pfam PF01381, HTH_3, 1 hit PF00717, Peptidase_S24, 1 hit |
SMARTi | View protein in SMART SM00530, HTH_XRE, 1 hit |
SUPFAMi | SSF47413, SSF47413, 1 hit SSF51306, SSF51306, 1 hit |
PROSITEi | View protein in PROSITE PS50943, HTH_CROC1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PRTR_PSEAE | |
Accessioni | Q06553Primary (citable) accession number: Q06553 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1996 | |
Last modified: | May 25, 2022 | |
This is version 124 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |