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UniProtKB - Q06432 (CCG1_HUMAN)

Entry version 165 (23 Feb 2022)
Sequence version 1 (01 Nov 1995)
Previous versions | rss
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Protein

Voltage-dependent calcium channel gamma-1 subunit

Gene

CACNG1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionCalcium channel, Ion channel, Voltage-gated channel
Biological processCalcium transport, Ion transport, Transport
LigandCalcium

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q06432

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q06432

Protein family/group databases

Transport Classification Database

More...TCDBi		8.A.16.1.1, the ca(+) channel auxiliary subunit Gama1-Gama8 (ccaGama) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Voltage-dependent calcium channel gamma-1 subunit
Alternative name(s):
Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CACNG1
Synonyms:CACNLG2 Publications
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:1405, CACNG1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		114209, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q06432

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000108878

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 10CytoplasmicCurated10
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei11 – 29HelicalBy similarityAdd BLAST19
Topological domaini30 – 108ExtracellularCuratedAdd BLAST79
Transmembranei109 – 129HelicalBy similarityAdd BLAST21
Topological domaini130 – 134CytoplasmicCurated5
Transmembranei135 – 155HelicalBy similarityAdd BLAST21
Topological domaini156 – 179ExtracellularCuratedAdd BLAST24
Transmembranei180 – 204HelicalBy similarityAdd BLAST25
Topological domaini205 – 222CytoplasmicCuratedAdd BLAST18

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		786

Open Targets

More...OpenTargetsi		ENSG00000108878

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA26015

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q06432, Tbio

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL2363032

Drug and drug target database

More...DrugBanki		DB13746, Bioallethrin
DB11148, Butamben
DB00343, Diltiazem
DB00228, Enflurane
DB00153, Ergocalciferol
DB00898, Ethanol
DB04842, Fluspirilene
DB00308, Ibutilide
DB00528, Lercanidipine
DB00421, Spironolactone

DrugCentral

More...DrugCentrali		Q06432

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CACNG1

Domain mapping of disease mutations (DMDM)

More...DMDMi		1168946

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001646691 – 222Voltage-dependent calcium channel gamma-1 subunitAdd BLAST222

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi43N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi57 ↔ 80By similarity
Glycosylationi79N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q06432

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q06432

PeptideAtlas

More...PeptideAtlasi		Q06432

PRoteomics IDEntifications database

More...PRIDEi		Q06432

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		58446

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q06432, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q06432

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q06432

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Skeletal muscle.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000108878, Expressed in gastrocnemius and 106 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q06432, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000108878, Group enriched (skeletal muscle, tongue)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		107240, 42 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-3192, Skeletal muscle VGCC complex

Protein interaction database and analysis system

More...IntActi		Q06432, 17 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000226021

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		Q06432

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q06432, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q06432

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QT5N, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000007786

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_093876_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q06432

Identification of Orthologs from Complete Genome Data

More...OMAi		CACTGFV

Database of Orthologous Groups

More...OrthoDBi		1261253at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q06432

TreeFam database of animal gene trees

More...TreeFami		TF331651

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004031, PMP22/EMP/MP20/Claudin
IPR005421, VDCC_g1su
IPR008368, VDCC_gsu

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13903, Claudin_2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01792, VDCCGAMMA
PR01601, VDCCGAMMA1

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q06432-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQTKMLKVR VTLFCILAGI VLAMTAVVTD HWAVLSPHME HHNTTCEAAH 
        60         70         80         90        100
FGLWRICTKR IPMDDSKTCG PITLPGEKNC SYFRHFNPGE SSEIFEFTTQ 
       110        120        130        140        150
KEYSISAAAI AIFSLGFIIL GSLCVLLSLG KKRDYLLRPA SMFYAFAGLC 
       160        170        180        190        200
ILVSVEVMRQ SVKRMIDSED TVWIEYYYSW SFACACAAFI LLFLGGLALL 
       210        220 
LFSLPRMPRN PWESCMDAEP EH
Length:222
Mass (Da):25,028
Last modified:November 1, 1995 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEFEC34266CFC47CB
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_012063196G → S. Corresponds to variant dbSNP:rs1799938Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
L07738 mRNA Translation: AAA51904.1
AK313852 mRNA Translation: BAG36580.1
CH471099 Genomic DNA Translation: EAW89022.1
BC069493 mRNA Translation: AAH69493.1
BC113486 mRNA Translation: AAI13487.1
BC113492 mRNA Translation: AAI13493.1
Z19603 Genomic DNA Translation: CAA79671.1
Z19587 Genomic DNA Translation: CAB62573.1 Sequence problems.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS11668.1

Protein sequence database of the Protein Information Resource

More...PIRi		A46658

NCBI Reference Sequences

More...RefSeqi		NP_000718.1, NM_000727.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000226021; ENSP00000226021; ENSG00000108878

Database of genes from NCBI RefSeq genomes

More...GeneIDi		786

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:786

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000226021.5; ENSP00000226021.3; NM_000727.4; NP_000718.1

UCSC genome browser

More...UCSCi		uc002jfu.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L07738 mRNA Translation: AAA51904.1
AK313852 mRNA Translation: BAG36580.1
CH471099 Genomic DNA Translation: EAW89022.1
BC069493 mRNA Translation: AAH69493.1
BC113486 mRNA Translation: AAI13487.1
BC113492 mRNA Translation: AAI13493.1
Z19603 Genomic DNA Translation: CAA79671.1
Z19587 Genomic DNA Translation: CAB62573.1 Sequence problems.
CCDSiCCDS11668.1
PIRiA46658
RefSeqiNP_000718.1, NM_000727.3

3D structure databases

SMRiQ06432
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi107240, 42 interactors
ComplexPortaliCPX-3192, Skeletal muscle VGCC complex
IntActiQ06432, 17 interactors
STRINGi9606.ENSP00000226021

Chemistry databases

BindingDBiQ06432
ChEMBLiCHEMBL2363032
DrugBankiDB13746, Bioallethrin
DB11148, Butamben
DB00343, Diltiazem
DB00228, Enflurane
DB00153, Ergocalciferol
DB00898, Ethanol
DB04842, Fluspirilene
DB00308, Ibutilide
DB00528, Lercanidipine
DB00421, Spironolactone
DrugCentraliQ06432

Protein family/group databases

TCDBi8.A.16.1.1, the ca(+) channel auxiliary subunit Gama1-Gama8 (ccaGama) family

PTM databases

GlyGeniQ06432, 2 sites
iPTMnetiQ06432
PhosphoSitePlusiQ06432

Genetic variation databases

BioMutaiCACNG1
DMDMi1168946

Proteomic databases

MassIVEiQ06432
PaxDbiQ06432
PeptideAtlasiQ06432
PRIDEiQ06432
ProteomicsDBi58446

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		19201, 186 antibodies from 28 providers

The DNASU plasmid repository

More...DNASUi		786

Genome annotation databases

EnsembliENST00000226021; ENSP00000226021; ENSG00000108878
GeneIDi786
KEGGihsa:786
MANE-SelectiENST00000226021.5; ENSP00000226021.3; NM_000727.4; NP_000718.1
UCSCiuc002jfu.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		786
DisGeNETi786

GeneCards: human genes, protein and diseases

More...GeneCardsi		CACNG1
HGNCiHGNC:1405, CACNG1
HPAiENSG00000108878, Group enriched (skeletal muscle, tongue)
MIMi114209, gene
neXtProtiNX_Q06432
OpenTargetsiENSG00000108878
PharmGKBiPA26015
VEuPathDBiHostDB:ENSG00000108878

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QT5N, Eukaryota
GeneTreeiENSGT00390000007786
HOGENOMiCLU_093876_0_0_1
InParanoidiQ06432
OMAiCACTGFV
OrthoDBi1261253at2759
PhylomeDBiQ06432
TreeFamiTF331651

Enzyme and pathway databases

PathwayCommonsiQ06432
SignaLinkiQ06432

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		786, 16 hits in 1033 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		CACNG1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		786
PharosiQ06432, Tbio

Protein Ontology

More...PROi		PR:Q06432
RNActiQ06432, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000108878, Expressed in gastrocnemius and 106 other tissues
GenevisibleiQ06432, HS

Family and domain databases

InterProiView protein in InterPro
IPR004031, PMP22/EMP/MP20/Claudin
IPR005421, VDCC_g1su
IPR008368, VDCC_gsu
PfamiView protein in Pfam
PF13903, Claudin_2, 1 hit
PRINTSiPR01792, VDCCGAMMA
PR01601, VDCCGAMMA1

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCG1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q06432
Secondary accession number(s): B2R9N3, Q14D59
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 23, 2022
This is version 165 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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