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Entry version 134 (02 Jun 2021)
Sequence version 1 (01 Nov 1996)
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Protein

Serine/threonine-protein phosphatase 1 regulatory subunit PIG1

Gene

PIG1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulates the activity of glycogen synthase. It is most probably a regulatory subunit for protein phosphatase type 1.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • glycogen biosynthetic process Source: UniProtKB-KW
  • regulation of glycogen biosynthetic process Source: SGD

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processGlycogen biosynthesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SCE-3322077, Glycogen synthesis

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
CBM21, Carbohydrate-Binding Module Family 21

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Serine/threonine-protein phosphatase 1 regulatory subunit PIG1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PIG1
Ordered Locus Names:YLR273C
ORF Names:L9328.2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XII

Organism-specific databases

Saccharomyces Genome Database

More...
SGDi
S000004263, PIG1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:YLR273C

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000715191 – 648Serine/threonine-protein phosphatase 1 regulatory subunit PIG1Add BLAST648

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q06216

PRoteomics IDEntifications database

More...
PRIDEi
Q06216

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q06216

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
31541, 47 interactors

Database of interacting proteins

More...
DIPi
DIP-2918N

Protein interaction database and analysis system

More...
IntActi
Q06216, 9 interactors

Molecular INTeraction database

More...
MINTi
Q06216

STRING: functional protein association networks

More...
STRINGi
4932.YLR273C

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q06216, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q06216

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini201 – 331CBM21PROSITE-ProRule annotationAdd BLAST131

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni20 – 52DisorderedSequence analysisAdd BLAST33
Regioni593 – 629DisorderedSequence analysisAdd BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi593 – 615Polar residuesSequence analysisAdd BLAST23

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3986, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000176558

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_028211_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
IDCEIEP

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.2440, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005036, CBM21_dom
IPR038175, CBM21_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03370, CBM_21, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51159, CBM21, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q06216-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPYSHGKKLK PSLKLAKTIS TSSFVSSTTS NSFSPLEDST SASSSTSSSS
60 70 80 90 100
SGKSVRFAAH LYTVKKFNTK LAPISISEKA ASNLTRNLHN NAIPLTFPFI
110 120 130 140 150
GGEDHRYSLD ILDYSDLEYD NKDVEYDNES DVEDNAMLMH DRSMFIEKEI
160 170 180 190 200
LCFGEEETFD MADWKLVSNN LNPFKSDYKV DVTGLEDKIF KYLNGQNIKV
210 220 230 240 250
HSLELSDPVS YEDICSNNFG NCQIWGLIFV NNLNFEKKIE IKFTLNNWAD
260 270 280 290 300
IHYINAHYNK SVTPHVDEFK FIIDISALKL NLISKNLIYT NFFERKTTCL
310 320 330 340 350
LNLQFCCRYD VNGFEYRSFY DNNDYKNYEI TISLSAINLN RAVSNSSIFN
360 370 380 390 400
SNLGPSKMGA SNAEVTMSKN NENSKKPLRK FIKDTDYYND SPLKHKFYQS
410 420 430 440 450
FETKAACKTE PVSQTFKAET IDCEIEPFNY FFEPPDSQTN EDMSDSSYDL
460 470 480 490 500
SLQDFNYWEF SNHGLGKALA DSDILQFKNY PKPEPFSRPP IIDDTFTLNT
510 520 530 540 550
DDRTLGSKTQ KLEDNLAKEW KSAKTRTTLN ETPLHDDEHR TSFTYTTWNN
560 570 580 590 600
STDTLMKRKE ERPVESASCS QLSIATIKAE EDLLYQDYIN SGRESSSPEI
610 620 630 640
SPLNTTTSLP FFPGDNMSDS SGEYEERTSL SPNKIHIFRD YFYKSPSP
Length:648
Mass (Da):74,146
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB95853040B225BD7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti228I → K in AAU09763 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U17245 Genomic DNA Translation: AAB67365.1
AY723846 Genomic DNA Translation: AAU09763.1
BK006945 Genomic DNA Translation: DAA09586.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S51409

NCBI Reference Sequences

More...
RefSeqi
NP_013375.1, NM_001182160.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YLR273C_mRNA; YLR273C; YLR273C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
850979

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YLR273C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17245 Genomic DNA Translation: AAB67365.1
AY723846 Genomic DNA Translation: AAU09763.1
BK006945 Genomic DNA Translation: DAA09586.1
PIRiS51409
RefSeqiNP_013375.1, NM_001182160.1

3D structure databases

SMRiQ06216
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi31541, 47 interactors
DIPiDIP-2918N
IntActiQ06216, 9 interactors
MINTiQ06216
STRINGi4932.YLR273C

Protein family/group databases

CAZyiCBM21, Carbohydrate-Binding Module Family 21

PTM databases

iPTMnetiQ06216

Proteomic databases

PaxDbiQ06216
PRIDEiQ06216

Genome annotation databases

EnsemblFungiiYLR273C_mRNA; YLR273C; YLR273C
GeneIDi850979
KEGGisce:YLR273C

Organism-specific databases

SGDiS000004263, PIG1
VEuPathDBiFungiDB:YLR273C

Phylogenomic databases

eggNOGiKOG3986, Eukaryota
GeneTreeiENSGT00940000176558
HOGENOMiCLU_028211_0_0_1
OMAiIDCEIEP

Enzyme and pathway databases

ReactomeiR-SCE-3322077, Glycogen synthesis

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q06216
RNActiQ06216, protein

Family and domain databases

Gene3Di2.60.40.2440, 1 hit
InterProiView protein in InterPro
IPR005036, CBM21_dom
IPR038175, CBM21_dom_sf
PfamiView protein in Pfam
PF03370, CBM_21, 1 hit
PROSITEiView protein in PROSITE
PS51159, CBM21, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPIG1_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q06216
Secondary accession number(s): D6VYS0, E9P964
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: June 2, 2021
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names
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