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UniProtKB - Q06157 (AMDR_ASPOR)
Protein
Acetamidase regulatory protein
Gene
amdR
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Functioni
Positively regulates the expression of genes involved in the catabolism of certain amides, omega amino acids, and lactams.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 26 – 59 | Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST | 34 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: InterPro
- zinc ion binding Source: InterPro
GO - Biological processi
- transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | Activator, DNA-binding |
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Acetamidase regulatory protein |
Gene namesi | Name:amdR ORF Names:AO090003000962 |
Organismi | Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
Taxonomic identifieri | 510516 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Aspergillaceae › Aspergillus › Aspergillus subgen. Circumdati › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | FungiDB:AO090003000962 |
Subcellular locationi
Nucleus
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000114935 | 1 – 775 | Acetamidase regulatory proteinAdd BLAST | 775 |
Expressioni
Inductioni
By omega amino acids.
Structurei
3D structure databases
AlphaFoldDBi | Q06157 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 20 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 126 – 159 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 630 – 699 | DisorderedSequence analysisAdd BLAST | 70 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 19 | Polar residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 126 – 156 | Polar residuesSequence analysisAdd BLAST | 31 | |
Compositional biasi | 658 – 675 | Polar residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 676 – 690 | Pro residuesSequence analysisAdd BLAST | 15 |
Phylogenomic databases
HOGENOMi | CLU_006329_4_0_1 |
OMAi | QEDLRMA |
Family and domain databases
CDDi | cd00067, GAL4, 1 hit |
Gene3Di | 4.10.240.10, 1 hit |
InterProi | View protein in InterPro IPR007219, Transcription_factor_dom_fun IPR001138, Zn2-C6_fun-type_DNA-bd IPR036864, Zn2-C6_fun-type_DNA-bd_sf |
Pfami | View protein in Pfam PF04082, Fungal_trans, 1 hit PF00172, Zn_clus, 1 hit |
SMARTi | View protein in SMART SM00906, Fungal_trans, 1 hit SM00066, GAL4, 1 hit |
SUPFAMi | SSF57701, SSF57701, 1 hit |
PROSITEi | View protein in PROSITE PS00463, ZN2_CY6_FUNGAL_1, 1 hit PS50048, ZN2_CY6_FUNGAL_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q06157-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSTAHNSQP STGNGVTKRK SGSAACIHCH RRKVRCDARI VGLPCSNCRS
60 70 80 90 100
AGKADCRIHE KKKRLAVRSI LDPVPIRCRP PPDSDSTPKL LPSTPIQPNA
110 120 130 140 150
FTTAFRGVQP DVTSPVAAGA QIIQSPHSSY TNGNHLSNNR GSQPITETQT
160 170 180 190 200
FTRQPGADRS MELENNADLE KRLVKLIDEE ESGSREIQRG VRAIYVGHEL
210 220 230 240 250
SNMSFLIRQQ RDKDDDVYHF AGNEIPRRQL RTGHDQLLMD ALTLPEPALA
260 270 280 290 300
DELVEAYFMH VNPGYPIIEE DLFMTQYRNR DPADPPPILL LQAILLVGAH
310 320 330 340 350
VTRPKAERDA LKEIFFRRVK WLFDSRIERN RDIMVQAALL MTWHSDSADD
360 370 380 390 400
DVAANAHYWV GVAARIATGL GMHRNPVSSK FVPRDRRMWR RLWYILVQFD
410 420 430 440 450
VMVSLSYGRP QAINLEDSDV SPLTPSDFEG CGSRVQAEYV IHFSELCTMI
460 470 480 490 500
PYIVRERFGL RVSAERRKAA LQEADEALAN WSLKLPDSLR LRASDMDPWS
510 520 530 540 550
AMLHLTYNNF LILLHRPHPR ASAYSDDYGP HDAEICSAAA GVIASIFEEL
560 570 580 590 600
RLNDRLKFLW YSGVHTLFTA MIQVRVELRF SNPVLAINAL RRFDSASYSL
610 620 630 640 650
RELAEYWSHA NTILRLFQDS KRLQEDLRMA TSERPRRFST HDQNKNTTNP
660 670 680 690 700
SNPHPTPTPN LNSNTTIQSA QTEPRPPYEV PTPESPRMPP TTMSPHQNQP
710 720 730 740 750
FDSWIPSSHL ASVDPIDQPR EFLDWRQLFS FTDPDQSVLP VPMEGLPELE
760 770
DEWRQIYWQE TPMSDLLQDG GWMHG
Sequence cautioni
The sequence AAA32686 differs from that shown. Reason: Erroneous gene model prediction.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 727 – 728 | QL → PV in AAA32686 (PubMed:1452021).Curated | 2 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M96953 Genomic DNA Translation: AAA32686.1 Sequence problems. AP007155 Genomic DNA Translation: BAE58075.1 |
PIRi | JQ1956 |
RefSeqi | XP_001820077.1, XM_001820025.2 |
Genome annotation databases
EnsemblFungii | BAE58075; BAE58075; AO090003000962 |
GeneIDi | 5992060 |
KEGGi | aor:AO090003000962 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M96953 Genomic DNA Translation: AAA32686.1 Sequence problems. AP007155 Genomic DNA Translation: BAE58075.1 |
PIRi | JQ1956 |
RefSeqi | XP_001820077.1, XM_001820025.2 |
3D structure databases
AlphaFoldDBi | Q06157 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 510516.Q06157 |
Genome annotation databases
EnsemblFungii | BAE58075; BAE58075; AO090003000962 |
GeneIDi | 5992060 |
KEGGi | aor:AO090003000962 |
Organism-specific databases
VEuPathDBi | FungiDB:AO090003000962 |
Phylogenomic databases
HOGENOMi | CLU_006329_4_0_1 |
OMAi | QEDLRMA |
Family and domain databases
CDDi | cd00067, GAL4, 1 hit |
Gene3Di | 4.10.240.10, 1 hit |
InterProi | View protein in InterPro IPR007219, Transcription_factor_dom_fun IPR001138, Zn2-C6_fun-type_DNA-bd IPR036864, Zn2-C6_fun-type_DNA-bd_sf |
Pfami | View protein in Pfam PF04082, Fungal_trans, 1 hit PF00172, Zn_clus, 1 hit |
SMARTi | View protein in SMART SM00906, Fungal_trans, 1 hit SM00066, GAL4, 1 hit |
SUPFAMi | SSF57701, SSF57701, 1 hit |
PROSITEi | View protein in PROSITE PS00463, ZN2_CY6_FUNGAL_1, 1 hit PS50048, ZN2_CY6_FUNGAL_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | AMDR_ASPOR | |
Accessioni | Q06157Primary (citable) accession number: Q06157 Secondary accession number(s): Q00225, Q2UK40 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 1, 1994 |
Last sequence update: | May 2, 2006 | |
Last modified: | May 25, 2022 | |
This is version 114 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |