UniProtKB - Q06091 (SN309_YEAST)
Pre-mRNA-splicing factor SNT309
SNT309
Functioni
Miscellaneous
GO - Biological processi
- mRNA splicing, via spliceosome Source: SGD
Keywordsi
Biological process | mRNA processing, mRNA splicing |
Names & Taxonomyi
Protein namesi | Recommended name: Pre-mRNA-splicing factor SNT309Alternative name(s): PRP19-associated complex protein 25 Synergistic to PRP19 mutation protein 309 |
Gene namesi | Name:SNT309 Synonyms:NTC25 Ordered Locus Names:YPR101W |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YPR101W |
SGDi | S000006305, SNT309 |
Subcellular locationi
Nucleus
- Nucleus 1 Publication
Nucleus
- U2-type catalytic step 1 spliceosome Source: SGD
Other locations
- Prp19 complex Source: SGD
Keywords - Cellular componenti
Nucleus, SpliceosomePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000071999 | 1 – 175 | Pre-mRNA-splicing factor SNT309Add BLAST | 175 |
Proteomic databases
MaxQBi | Q06091 |
PaxDbi | Q06091 |
PRIDEi | Q06091 |
Interactioni
Subunit structurei
Belongs to the NTC complex (or PRP19-associated complex), composed of at least CEF1, CLF1, ISY1, NTC20, SNT309, SYF1, SYF2, and PRP19. The NTC complex associates with the spliceosome after the release of the U1 and U4 snRNAs and forms the CWC spliceosome subcomplex (or CEF1-associated complex) reminiscent of a late-stage spliceosome composed also of the U2, U5 and U6 snRNAs and at least BUD13, BUD31, BRR2, CDC40, CUS1, CWC2, CWC15, CWC21, CWC22, CWC23, CWC24, CWC25, CWC27, ECM2, HSH155, IST3, LEA1, MSL1, PRP8, PRP9, PRP11, PRP21, PRP22, PRP45, PRP46, SLU7, SMB1, SMD1, SMD2, SMD3, SMX2, SMX3, SNU114, SPP2, RSE1 and YJU2.
Interacts with PRP19.
4 PublicationsBinary interactionsi
Hide detailsQ06091
With | #Exp. | IntAct |
---|---|---|
CLF1 [Q12309] | 4 | EBI-818,EBI-484 |
NTC20 [P38302] | 2 | EBI-818,EBI-20921 |
PRP19 [P32523] | 8 | EBI-818,EBI-493 |
Protein-protein interaction databases
BioGRIDi | 36267, 300 interactors |
ComplexPortali | CPX-1651, PRP19-associated complex CPX-1885, NineTeen complex |
DIPi | DIP-2864N |
IntActi | Q06091, 35 interactors |
MINTi | Q06091 |
STRINGi | 4932.YPR101W |
Miscellaneous databases
RNActi | Q06091, protein |
Structurei
Secondary structure
3D structure databases
SMRi | Q06091 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502S9WN, Eukaryota |
HOGENOMi | CLU_119596_0_0_1 |
InParanoidi | Q06091 |
OMAi | NQWAINN |
i Sequence
Sequence statusi: Complete.
10 20 30 40 50
MDGLSFVDKG KIPDGYKNEI DQLVKKEFAN IKREPVHPEI RGILAKRKGA
60 70 80 90 100
DNSVSTLTNA LYTEYLKQRN NKKRRTPDFN DDDDTLFLEE YRRKYPRIDT
110 120 130 140 150
SRYIPNESSE VSLLGIVDSY LKHQEIVLDT LLPQTVSNQW RINNDYIRQT
160 170
CTIVEEMNIQ QRKQINDLEI YRKRL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U32445 Genomic DNA Translation: AAB68071.1 AY693233 Genomic DNA Translation: AAT93252.1 BK006949 Genomic DNA Translation: DAA11515.1 |
PIRi | S59766 |
RefSeqi | NP_015426.1, NM_001184198.1 |
Genome annotation databases
EnsemblFungii | YPR101W_mRNA; YPR101W; YPR101W |
GeneIDi | 856216 |
KEGGi | sce:YPR101W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U32445 Genomic DNA Translation: AAB68071.1 AY693233 Genomic DNA Translation: AAT93252.1 BK006949 Genomic DNA Translation: DAA11515.1 |
PIRi | S59766 |
RefSeqi | NP_015426.1, NM_001184198.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5GM6 | electron microscopy | 3.50 | t | 1-175 | [»] | |
5GMK | electron microscopy | 3.40 | t | 1-175 | [»] | |
5LJ5 | electron microscopy | 3.80 | s | 1-175 | [»] | |
5MQ0 | electron microscopy | 4.17 | s | 1-175 | [»] | |
5WSG | electron microscopy | 4.00 | t | 1-175 | [»] | |
5Y88 | electron microscopy | 3.70 | G | 1-175 | [»] | |
5YLZ | electron microscopy | 3.60 | G | 1-175 | [»] | |
6BK8 | electron microscopy | 3.30 | y | 1-175 | [»] | |
6EXN | electron microscopy | 3.70 | s | 1-175 | [»] | |
6J6G | electron microscopy | 3.20 | t | 1-175 | [»] | |
6J6H | electron microscopy | 3.60 | t | 1-175 | [»] | |
6J6N | electron microscopy | 3.86 | t | 1-175 | [»] | |
6J6Q | electron microscopy | 3.70 | t | 1-175 | [»] | |
SMRi | Q06091 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 36267, 300 interactors |
ComplexPortali | CPX-1651, PRP19-associated complex CPX-1885, NineTeen complex |
DIPi | DIP-2864N |
IntActi | Q06091, 35 interactors |
MINTi | Q06091 |
STRINGi | 4932.YPR101W |
Proteomic databases
MaxQBi | Q06091 |
PaxDbi | Q06091 |
PRIDEi | Q06091 |
Genome annotation databases
EnsemblFungii | YPR101W_mRNA; YPR101W; YPR101W |
GeneIDi | 856216 |
KEGGi | sce:YPR101W |
Organism-specific databases
EuPathDBi | FungiDB:YPR101W |
SGDi | S000006305, SNT309 |
Phylogenomic databases
eggNOGi | ENOG502S9WN, Eukaryota |
HOGENOMi | CLU_119596_0_0_1 |
InParanoidi | Q06091 |
OMAi | NQWAINN |
Miscellaneous databases
PROi | PR:Q06091 |
RNActi | Q06091, protein |
Family and domain databases
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SN309_YEAST | |
Accessioni | Q06091Primary (citable) accession number: Q06091 Secondary accession number(s): D6W499 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 30, 2005 |
Last sequence update: | November 1, 1996 | |
Last modified: | October 7, 2020 | |
This is version 150 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Yeast chromosome XVI
Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD