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Entry version 97 (02 Jun 2021)
Sequence version 2 (26 Feb 2008)
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Protein

FHF complex subunit HOOK interacting protein 1A

Gene

FHIP1A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable component of the FTS/Hook/FHIP complex (FHF complex) (PubMed:32073997).

FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed:32073997).

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • protein localization to perinuclear region of cytoplasm Source: UniProtKB

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q05DH4

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
FHF complex subunit HOOK interacting protein 1ACurated
Short name:
FHIP1ACurated
Alternative name(s):
FTS and Hook-interacting protein like1 Publication
Short name:
FHIP-L1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FHIP1AImported
Synonyms:FAM160A1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:34237, FHIP1A

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q05DH4

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000164142.15

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
729830

Open Targets

More...
OpenTargetsi
ENSG00000164142

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162386739

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q05DH4, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM160A1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
189042274

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003195781 – 1040FHF complex subunit HOOK interacting protein 1AAdd BLAST1040

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q05DH4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q05DH4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q05DH4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q05DH4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q05DH4

PeptideAtlas

More...
PeptideAtlasi
Q05DH4

PRoteomics IDEntifications database

More...
PRIDEi
Q05DH4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
58407

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q05DH4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q05DH4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164142, Expressed in buccal mucosa cell and 136 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q05DH4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q05DH4, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000164142, Tissue enhanced (skeletal)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

May be a component of the FTS/Hook/FHIP complex (FHF complex), composed of AKTIP/FTS, FHIP1B, and one or more members of the Hook family of proteins HOOK1, HOOK2, and HOOK3. May interact directly with AKTIP/FTS.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
610225, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q05DH4, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000413196

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q05DH4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q05DH4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni555 – 613DisorderedSequence analysisAdd BLAST59
Regioni653 – 746DisorderedSequence analysisAdd BLAST94
Regioni769 – 808DisorderedSequence analysisAdd BLAST40

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi565 – 579Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi674 – 691Polar residuesSequence analysisAdd BLAST18
Compositional biasi692 – 722Basic and acidic residuesSequence analysisAdd BLAST31
Compositional biasi731 – 745Polar residuesSequence analysisAdd BLAST15
Compositional biasi782 – 803Basic and acidic residuesSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FHIP family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3695, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182936

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007807_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q05DH4

Identification of Orthologs from Complete Genome Data

More...
OMAi
PMFRLQQ

Database of Orthologous Groups

More...
OrthoDBi
141539at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q05DH4

TreeFam database of animal gene trees

More...
TreeFami
TF313941

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019384, RetinoicA-induced_16-like

The PANTHER Classification System

More...
PANTHERi
PTHR21705, PTHR21705, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10257, RAI16-like, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q05DH4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMSSVSTESK LQQAVSLQGV DPETCMIVFK NHWAQVVKIL EKHDPLKNTQ
60 70 80 90 100
AKYGSIPPDE ASAVQNYVEH MLFLLIEEQA KDAAMGPILE FVVSENIMEK
110 120 130 140 150
LFLWSLRREF TDETKIEQLK MYEMLVTQSH QPLLHHKPIL KPLMMLLSSC
160 170 180 190 200
SGTTTPTVEE KLVVLLNQLC SILAKDPSIL ELFFHTSEDQ GAANFLIFSL
210 220 230 240 250
LIPFIHREGS VGQQARDALL FIMSLSAENT MVAHHIVENT YFCPVLATGL
260 270 280 290 300
SGLYSSLPTK LEEKGEEWHC LLKDDWLLLP SLVQFMNSLE FCNAVIQVAH
310 320 330 340 350
PLIRNQLVNY IYNGFLVPVL APALHKVTVE EVMTTTAYLD LFLRSISEPA
360 370 380 390 400
LLEIFLRFIL LHQHENVHIL DTLTSRINTP FRLCVVSLAL FRTLIGLHCE
410 420 430 440 450
DVMLQLVLRY LIPCNHMMLS QRWAVKERDC YSVSAAKLLA LTPVCCSSGI
460 470 480 490 500
TLTLGNQERD YILWSKCMHD TSGPVERPFP EAFSESACIV EYGKALDISY
510 520 530 540 550
LQYLWEAHTN ILRCMRDCRV WSALYDGDSP DPEMFLQSLT EEGSVSSACP
560 570 580 590 600
VFGLPQQLPR KTGPQLAPRK DKSQTELEWD DSYDTGISSG ADVGSPGPYD
610 620 630 640 650
DLEVSGPPAP IDPPKHIQEM KKNALLLFKG SYIEESDFQD DVMVYRLCAE
660 670 680 690 700
KDSEDMKDSQ EEAARPPAEA QAEVQSVPIN NGPLLSTQPE TDSEEEWNRD
710 720 730 740 750
NSDPFHSEPK EPKQEREPEA APESNSELAS PAPEAEHSSN LTAAHPESEE
760 770 780 790 800
LIAQYDQIIK ELDSGAEGLM EQNYPTPDPL LLTKEEEGKE ESKGEKEKEG
810 820 830 840 850
KKELEDEEDD FDSFIAEMPA VETVPSPFVG RDEAAFASRH PVRTQSTPFT
860 870 880 890 900
GPFISVVLSK LENMLENSLH VNLLLIGIIT QLASYPQPLL RSFLLNTNMV
910 920 930 940 950
FQPSVRSLYQ VLASVKNKIE QFASVERDFP GLLIQAQQYL LFRVDMSDMT
960 970 980 990 1000
PAALTKDPIQ EASRTGSGKN LLDGPPRVLQ PFLTHRTKVA EAPPNLPLPV
1010 1020 1030 1040
RNPMLAAALF PEFLKELAAL AQEHSILCYK ILGDFEDSCC
Length:1,040
Mass (Da):116,621
Last modified:February 26, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1B7A936DB0CAAFBD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RAG2D6RAG2_HUMAN
FHF complex subunit HOOK-interactin...
FHIP1A
60Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RF38D6RF38_HUMAN
FHF complex subunit HOOK-interactin...
FHIP1A
42Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RBF5D6RBF5_HUMAN
FHF complex subunit HOOK-interactin...
FHIP1A
40Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RDL4D6RDL4_HUMAN
FHF complex subunit HOOK-interactin...
FHIP1A
13Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH14937 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAH14937 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAC86147 differs from that shown. Aberrant splicing.Curated
The sequence BAC86147 differs from that shown. Reason: Frameshift.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_084431943R → C Found in siblings with familial natural-killer/T-cell lymphoma; unknown pathological significance. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC092611 Genomic DNA No translation available.
AC097455 Genomic DNA No translation available.
AK125363 mRNA Translation: BAC86147.1 Sequence problems.
BC014937 mRNA Translation: AAH14937.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47146.1

NCBI Reference Sequences

More...
RefSeqi
NP_001103447.1, NM_001109977.2
NP_001335623.1, NM_001348694.1
XP_005263256.1, XM_005263199.1
XP_011530522.1, XM_011532220.1
XP_011530523.1, XM_011532221.2
XP_011530525.1, XM_011532223.2
XP_011530526.1, XM_011532224.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000435205; ENSP00000413196; ENSG00000164142
ENST00000505231; ENSP00000421580; ENSG00000164142

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
729830

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:729830

UCSC genome browser

More...
UCSCi
uc003imj.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092611 Genomic DNA No translation available.
AC097455 Genomic DNA No translation available.
AK125363 mRNA Translation: BAC86147.1 Sequence problems.
BC014937 mRNA Translation: AAH14937.1 Sequence problems.
CCDSiCCDS47146.1
RefSeqiNP_001103447.1, NM_001109977.2
NP_001335623.1, NM_001348694.1
XP_005263256.1, XM_005263199.1
XP_011530522.1, XM_011532220.1
XP_011530523.1, XM_011532221.2
XP_011530525.1, XM_011532223.2
XP_011530526.1, XM_011532224.2

3D structure databases

SMRiQ05DH4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi610225, 11 interactors
IntActiQ05DH4, 3 interactors
STRINGi9606.ENSP00000413196

PTM databases

iPTMnetiQ05DH4
PhosphoSitePlusiQ05DH4

Genetic variation databases

BioMutaiFAM160A1
DMDMi189042274

Proteomic databases

EPDiQ05DH4
jPOSTiQ05DH4
MassIVEiQ05DH4
MaxQBiQ05DH4
PaxDbiQ05DH4
PeptideAtlasiQ05DH4
PRIDEiQ05DH4
ProteomicsDBi58407

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
48311, 12 antibodies

The DNASU plasmid repository

More...
DNASUi
729830

Genome annotation databases

EnsembliENST00000435205; ENSP00000413196; ENSG00000164142
ENST00000505231; ENSP00000421580; ENSG00000164142
GeneIDi729830
KEGGihsa:729830
UCSCiuc003imj.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
729830
DisGeNETi729830

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM160A1
HGNCiHGNC:34237, FHIP1A
HPAiENSG00000164142, Tissue enhanced (skeletal)
neXtProtiNX_Q05DH4
OpenTargetsiENSG00000164142
PharmGKBiPA162386739
VEuPathDBiHostDB:ENSG00000164142.15

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3695, Eukaryota
GeneTreeiENSGT00950000182936
HOGENOMiCLU_007807_0_0_1
InParanoidiQ05DH4
OMAiPMFRLQQ
OrthoDBi141539at2759
PhylomeDBiQ05DH4
TreeFamiTF313941

Enzyme and pathway databases

PathwayCommonsiQ05DH4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
729830, 5 hits in 986 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM160A1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
729830
PharosiQ05DH4, Tdark

Protein Ontology

More...
PROi
PR:Q05DH4
RNActiQ05DH4, protein

Gene expression databases

BgeeiENSG00000164142, Expressed in buccal mucosa cell and 136 other tissues
ExpressionAtlasiQ05DH4, baseline and differential
GenevisibleiQ05DH4, HS

Family and domain databases

InterProiView protein in InterPro
IPR019384, RetinoicA-induced_16-like
PANTHERiPTHR21705, PTHR21705, 1 hit
PfamiView protein in Pfam
PF10257, RAI16-like, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFHI1A_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q05DH4
Secondary accession number(s): Q6ZUS2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: June 2, 2021
This is version 97 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  2. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  3. Human entries with genetic variants
    List of human entries with genetic variants
  4. Human variants curated from literature reports
    Index of human variants curated from literature reports
  5. SIMILARITY comments
    Index of protein domains and families
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