UniProtKB - Q05DE9 (Q05DE9_HUMAN)
Protein
Submitted name:
FYB protein
Gene
FYB
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- immune response Source: InterPro
- integrin-mediated signaling pathway Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: FYB proteinImported |
Gene namesi | Name:FYBImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Cytoskeleton
- actin cytoskeleton Source: InterPro
Plasma Membrane
- plasma membrane Source: InterPro
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 511 – 572 | SH3InterPro annotationAdd BLAST | 62 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 502 | DisorderedSequence analysisAdd BLAST | 502 | |
Regioni | 598 – 644 | DisorderedSequence analysisAdd BLAST | 47 | |
Regioni | 659 – 747 | DisorderedSequence analysisAdd BLAST | 89 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 49 | PolarSequence analysisAdd BLAST | 49 | |
Compositional biasi | 237 – 251 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 276 – 292 | PolyampholyteSequence analysisAdd BLAST | 17 | |
Compositional biasi | 348 – 364 | Pro-richSequence analysisAdd BLAST | 17 | |
Compositional biasi | 368 – 389 | PolarSequence analysisAdd BLAST | 22 | |
Compositional biasi | 390 – 427 | Pro-richSequence analysisAdd BLAST | 38 | |
Compositional biasi | 462 – 502 | PolyampholyteSequence analysisAdd BLAST | 41 | |
Compositional biasi | 659 – 675 | PolyampholyteSequence analysisAdd BLAST | 17 | |
Compositional biasi | 720 – 741 | PolyampholyteSequence analysisAdd BLAST | 22 |
Keywords - Domaini
SH3 domainPROSITE-ProRule annotationARBA annotationFamily and domain databases
InterProi | View protein in InterPro IPR030635, FYB1 IPR043443, FYB1/2-like IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR16830, PTHR16830, 1 hit PTHR16830:SF13, PTHR16830:SF13, 1 hit |
Pfami | View protein in Pfam PF07653, SH3_2, 1 hit |
SMARTi | View protein in SMART SM00326, SH3, 1 hit |
SUPFAMi | SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS50002, SH3, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q05DE9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKYNTGGNP TEDVSVNSRP FRVTGPNSSS GIQARKNLFN NQGNASPPAG
60 70 80 90 100
PSNVPKFGSP KPPVAVKPSS EEKPDKEPKP PFLKPTGAGQ RFGTPASLTT
110 120 130 140 150
RDPEAKVGFL KPVGPKPINL PKEDSKPTFP WPPGNKPSLH SVNQDHDLKP
160 170 180 190 200
LGPKSGPTPP TSENEQKQAF PKLTGVKGKF MSASQDLEPK PLFPKPAFGQ
210 220 230 240 250
KPPLSTENSH EDESPMKNVS SSKGSPAPLG VRSKSGPLKP AREDSENKDH
260 270 280 290 300
AGEISSLPFP GVVLKPAASR GGPGLSKNGE EKKEDRKIDA AKNTFQSKIN
310 320 330 340 350
QEELASGTPP ARFPKAPSKL TVGGPWGQSQ EKEKGDKNSA TPKQKPLPPL
360 370 380 390 400
FTLGPPPPKP NRPPNVDLTK FHKTSSGNST SKGQTSYSTT SLPPPPPSHP
410 420 430 440 450
ASQPPLPASH PSQPPVPSLP PRNIKPPFDL KSPVNEDNQD GVTHSDGAGN
460 470 480 490 500
LDEEQDSEGE TYEDIEASKE REKKREKEEK KRLELEKKEQ KEKEKKEQEI
510 520 530 540 550
KKKFKLTGPI QVIHLAKACC DVKGGKNELS FKQGEQIEII RITDNPEGKW
560 570 580 590 600
LGRTARGSYG YIKTTAVEID YDSLKLKKDS LGAPSRPIED DQEVYDDVAE
610 620 630 640 650
QDDISSHSQS GSGGIFPPPP DDDIYDGIEE EDADDGSTLQ VQEKSNTWSW
660 670 680 690 700
GILKMLKGKD DRKKSIREKP KVSDSDNNEG SSFPAPPKQL DMGDEVYDDV
710 720 730 740
DTSDFPVSSA EMSQGTNFGK AKTEEKDLKK LKKQEKEEKD FRKKKKK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 747 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC015933 mRNA Translation: AAH15933.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC015933 mRNA Translation: AAH15933.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q05DE9 |
Organism-specific databases
PharmGKBi | PA28452 |
Miscellaneous databases
BioGRID-ORCSi | 2533, 1 hit in 845 CRISPR screens |
ChiTaRSi | FYB, human |
Gene expression databases
Genevisiblei | Q05DE9, HS |
Family and domain databases
InterProi | View protein in InterPro IPR030635, FYB1 IPR043443, FYB1/2-like IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR16830, PTHR16830, 1 hit PTHR16830:SF13, PTHR16830:SF13, 1 hit |
Pfami | View protein in Pfam PF07653, SH3_2, 1 hit |
SMARTi | View protein in SMART SM00326, SH3, 1 hit |
SUPFAMi | SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS50002, SH3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q05DE9_HUMAN | |
Accessioni | Q05DE9Primary (citable) accession number: Q05DE9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 14, 2006 |
Last sequence update: | November 14, 2006 | |
Last modified: | December 2, 2020 | |
This is version 79 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |