SMC2

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: SMC2 proteinImported
Gene namesⁱ	Name:SMC2Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA37833

PharmGKBⁱ

PA37833

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	Q05D74
PRIDEⁱ	Q05D74

Expressionⁱ

Gene expression databases

Genevisibleⁱ	Q05D74 HS

Genevisibleⁱ

Q05D74 HS

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	2 – 276	SMC_NInterPro annotationAdd BLAST		275

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	246 – 287	Sequence analysisAdd BLAST		42

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG0933 Eukaryota COG1196 LUCA

eggNOGⁱ

KOG0933 Eukaryota
COG1196 LUCA

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03273 ABC_SMC2_euk, 1 hit
InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR003395 RecF/RecN/SMC_N IPR027120 Smc2_ABC
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02463 SMC_N, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q05D74-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MHIKSIILEG FKSYAQRTEV NGFDPLFNAI TGLNGSGKSN ILDSICFLLG 
        60         70         80         90        100
ISNLSQVRAS NLQDLVYKNG QAGITKASVS ITFDNSDEKQ SPLGFEVHDE 
       110        120        130        140        150
ITVTRQVVIG GRNKYLINGV NANNTRVQDL FCSVGLNVNN PHFLIMQGRI 
       160        170        180        190        200
TKVLNMKPPE ILSMIEEAAG TRMYEYKKIA AQKTIEKKEA KLKEIKTILE 
       210        220        230        240        250
EEITPTIQKL KEERSSYLEY QKVMREIEHL SRLYIAYQFL LAEDTKVRSA 
       260        270        280 
EELKEMQDKV IKLQEELSEN DKKIKALNHE KKKKKKKKK

Length:289

Mass (Da):32,953

Last modified:November 14, 2006 - v1

Checksum:ⁱE74C3928BC5FA893

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	289	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC017845 mRNA Translation: AAH17845.1
NCBI Reference Sequences More...RefSeqⁱ	NP_006435.2, NM_006444.2
UniGeneⁱ	Hs.119023

Genome annotation databases

GeneIDⁱ	10592

GeneIDⁱ

10592

Protein	Similar proteins		Species	Score	Length	Source
Q05D74	SMC2 protein (Fragment)		HUMAN		356	UniRef90_Q6IPS5
SMC2 protein (Fragment)		HUMAN		291
SMC2 protein (Fragment)		HUMAN		289

Protein	Similar proteins		Species	Score	Length	Source
Q05D74	SMC2 protein (Fragment)		HUMAN		356	UniRef50_Q6IPS5
CLUMA_CG009645, isoform A		Clunio marinus		425
UPI0004F056A1		MERNU		340
UPI00051C8700		FULGA		340
UPI000771A32C		wheat stem sawfly		353
+2

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC017845 mRNA Translation: AAH17845.1
RefSeqⁱ	NP_006435.2, NM_006444.2
UniGeneⁱ	Hs.119023

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PeptideAtlasⁱ	Q05D74
PRIDEⁱ	Q05D74

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	10592

GeneIDⁱ

10592

Organism-specific databases

CTDⁱ	10592
PharmGKBⁱ	PA37833

Phylogenomic databases

eggNOGⁱ	KOG0933 Eukaryota COG1196 LUCA

eggNOGⁱ

KOG0933 Eukaryota
COG1196 LUCA

Miscellaneous databases

ChiTaRSⁱ	SMC2 human
GenomeRNAiⁱ	10592

Gene expression databases

Genevisibleⁱ	Q05D74 HS

Genevisibleⁱ

Q05D74 HS

Family and domain databases

CDDⁱ	cd03273 ABC_SMC2_euk, 1 hit
InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR003395 RecF/RecN/SMC_N IPR027120 Smc2_ABC
Pfamⁱ	View protein in Pfam PF02463 SMC_N, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q05D74_HUMAN
Accessionⁱ	Q05D74Primary (citable) accession number: Q05D74
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 14, 2006
	Last sequence update:	November 14, 2006
	Last modified:	November 7, 2018
	This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - Q05D74 (Q05D74_HUMAN)

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SMC2 protein

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

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Supporting data

UniProtKB - Q05D74 (Q05D74_HUMAN)

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SMC2 protein

SMC2

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

UniProt is an ELIXIR core data resource

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ