UniProtKB - Q05D74 (Q05D74_HUMAN)
Protein
Structural maintenance of chromosomes protein 2
Gene
SMC2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Structural maintenance of chromosomes protein 2ARBA annotation |
Gene namesi | Name:SMC2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- Chromosome ARBA annotation
Other locations
- chromosome Source: UniProtKB-SubCell
Keywords - Cellular componenti
ChromosomeARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 276 | SMC_NInterPro annotationAdd BLAST | 275 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 246 – 287 | Sequence analysisAdd BLAST | 42 |
Keywords - Domaini
Coiled coilSequence analysisFamily and domain databases
CDDi | cd03273, ABC_SMC2_euk, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR003395, RecF/RecN/SMC_N IPR027120, Smc2_ABC |
Pfami | View protein in Pfam PF02463, SMC_N, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q05D74-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MHIKSIILEG FKSYAQRTEV NGFDPLFNAI TGLNGSGKSN ILDSICFLLG
60 70 80 90 100
ISNLSQVRAS NLQDLVYKNG QAGITKASVS ITFDNSDEKQ SPLGFEVHDE
110 120 130 140 150
ITVTRQVVIG GRNKYLINGV NANNTRVQDL FCSVGLNVNN PHFLIMQGRI
160 170 180 190 200
TKVLNMKPPE ILSMIEEAAG TRMYEYKKIA AQKTIEKKEA KLKEIKTILE
210 220 230 240 250
EEITPTIQKL KEERSSYLEY QKVMREIEHL SRLYIAYQFL LAEDTKVRSA
260 270 280
EELKEMQDKV IKLQEELSEN DKKIKALNHE KKKKKKKKK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 289 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC017845 mRNA Translation: AAH17845.1 |
RefSeqi | NP_006435.2, NM_006444.2 |
Genome annotation databases
GeneIDi | 10592 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC017845 mRNA Translation: AAH17845.1 |
RefSeqi | NP_006435.2, NM_006444.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q05D74 |
Genome annotation databases
GeneIDi | 10592 |
Organism-specific databases
CTDi | 10592 |
PharmGKBi | PA37833 |
Miscellaneous databases
BioGRID-ORCSi | 10592, 718 hits in 849 CRISPR screens |
ChiTaRSi | SMC2, human |
GenomeRNAii | 10592 |
Gene expression databases
Genevisiblei | Q05D74, HS |
Family and domain databases
CDDi | cd03273, ABC_SMC2_euk, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR003395, RecF/RecN/SMC_N IPR027120, Smc2_ABC |
Pfami | View protein in Pfam PF02463, SMC_N, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q05D74_HUMAN | |
Accessioni | Q05D74Primary (citable) accession number: Q05D74 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 14, 2006 |
Last sequence update: | November 14, 2006 | |
Last modified: | December 2, 2020 | |
This is version 75 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |