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  1. 1
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Tissue: Primary B-Cells.
    Source: UniProtKB/TrEMBL (unreviewed).

    This publication is cited by 50448 other entries.

  2. 2
    "Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene."
    Cho J.-Y., Akbarali Y., Zerbini L.F., Gu X., Boltax J., Wang Y., Oettgen P., Zhang D.-E., Libermann T.A.
    J. Biol. Chem. 279:19512-19522(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: transcription of the B cell-specific blk gene is regulated by NERF/ELF-2 and AMl1.
    Source: GeneRIF:640.

    This publication is cited by 1 and mapped to 13 other entries.

  3. 3
    Category: Function, Pathology & Biotech, Sequences.
    Annotation: Genome-wide association study of gene-disease association. (HuGE Navigator); identified and confirmed through replication two new genetic loci for SLE: a promoter-region allele associated with reduced expression of BLK and increased expression of C8orf13 and variants in the ITGAM-ITGAX region. [GeneRIF:640]. Associated with IMMUNE: systemic lupus erythematosus. [GAD:597005].
    Source: GeneRIF:640, GAD:597005.

    This publication is mapped to 268 other entries.

  4. 4
    "Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population."
    Ito I., Kawasaki A., Ito S., Hayashi T., Goto D., Matsumoto I., Tsutsumi A., Hom G., Graham R.R., Takasaki Y., Hashimoto H., Ohashi J., Behrens T.W., Sumida T., Tsuchiya N.
    Arthritis Rheum. 60:553-558(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); The association of the C8orf13-BLK region with systemic lupus erythematosus was replicated in a Japanese population.
    Source: GeneRIF:640.

    This publication is mapped to 4 other entries.

  5. 5
    "Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese."
    Yang W., Ng P., Zhao M., Hirankarn N., Lau C.S., Mok C.C., Chan T.M., Wong R.W., Lee K.W., Mok M.Y., Wong S.N., Avihingsanon Y., Lee T.L., Ho M.H., Lee P.P., Wong W.H., Lau Y.L.
    Genes Immun. 10:219-226(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Our data confirmed association of STAT4 (rs7574865 odds ratio (OR) =1.71 P=3.55 x 10(-23)) and BLK (rs13277113 OR=0.77 P=1.34 x 10(-5)) with SLE; Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:640.

    This publication is mapped to 23 other entries.

  6. 6
    Category: Sequences.
    Annotation: Blk is constitutively tyrosine phosphorylated in malignant cutaneous T-cell lymphoma cell lines and spontaneously active in kinase assays.
    Source: GeneRIF:640.

    This publication is mapped to 2 other entries.

  7. 7
    "REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis."
    Gregersen P.K., Amos C.I., Lee A.T., Lu Y., Remmers E.F., Kastner D.L., Seldin M.F., Criswell L.A., Plenge R.M., Holers V.M., Mikuls T.R., Sokka T., Moreland L.W., Bridges S.L. Jr., Xie G., Begovich A.B., Siminovitch K.A.
    Nat. Genet. 41:820-823(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Observational study and genome-wide association study of gene-disease association and gene-gene interaction. (HuGE Navigator). [GeneRIF:640]. Associated with IMMUNE: rheumatoid arthritis. [GAD:597003].
    Source: GAD:597003, GeneRIF:640.

    This publication is mapped to 26 other entries.

  8. 8
    "Association of STAT4 and BLK, but not BANK1 or IRF5, with primary antiphospholipid syndrome."
    Yin H., Borghi M.O., Delgado-Vega A.M., Tincani A., Meroni P.L., Alarcon-Riquelme M.E.
    Arthritis Rheum. 60:2468-2471(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); STAT4 and BLK displayed a strong genetic association with primary antiphospholipid syndrome.
    Source: GeneRIF:640.

    This publication is mapped to 33 other entries.

  9. 9
    Category: Sequences.
    Annotation: Findings point to BLK as a previously unrecognized modulator of beta-cell function the deficit of which may lead to the development of diabetes.
    Source: GeneRIF:640.

    This publication is mapped to 1 other entry.

  10. 10
    "Replication of association between FAM167A(C8orf13)-BLK region and rheumatoid arthritis in a Japanese population."
    Ito I., Kawasaki A., Ito S., Kondo Y., Sugihara M., Horikoshi M., Hayashi T., Goto D., Matsumoto I., Tsutsumi A., Takasaki Y., Hashimoto H., Matsuta K., Sumida T., Tsuchiya N.
    Ann. Rheum. Dis. 69:936-937(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); Results indicate the FAM167A-BLK region may be a shared genetic factor for a number of autoimmune diseases in multiple populations but the genetic contribution may be grater in Asian populations.
    Source: GeneRIF:640.

    This publication is mapped to 4 other entries.

  11. 11
    Category: Sequences.
    Annotation: genetic polymorphism is associated with systemic sclerosis in North-American and European populations.
    Source: GeneRIF:640.

    This publication is mapped to 2 other entries.

  12. 12
    Category: Function, Pathology & Biotech, Sequences.
    Annotation: Associated with IMMUNE: systemic lupus erythematosus. [GAD:597002]. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator). [GeneRIF:640].
    Source: GeneRIF:640, GAD:597002.

    This publication is mapped to 1826 other entries.

  13. 13
    Category: Sequences.
    Annotation: study evaluated SNP rs2248932 from BLK and further defined its role in systemic lupus erythematosus (SLE) risk; its association with SLE was confirmed in Chinese Han population.
    Source: GeneRIF:640.

    This publication is mapped to 2 other entries.

  14. 14
    Category: Pathology & Biotech, Sequences.
    Annotation: Our findings indicate that the rs13277113A allele is associated not only with SLE but also with SSc and that the FAM167A-BLK region is a common genetic risk factor for both SLE and SSc.
    Source: GeneRIF:640.

    This publication is mapped to 4 other entries.

  15. 15
    "IRF5 is associated with primary antiphospholipid syndrome, but is not a major risk factor."
    Fredi M., Tincani A., Yin H., Delgado-Vega A.M., Borghi M.O., Meroni P.L., Alarcon-Riquelme M.E.
    Arthritis Rheum. 62:1201-1202(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:640.

    This publication is mapped to 33 other entries.

  16. 16
    Category: Sequences.
    Annotation: our results do not support a major implication of the C8orf13-BLK gene region in susceptibility to Giant cell arteritis; Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:640.

    This publication is mapped to 4 other entries.

  17. 17
    "Association of IRF5, STAT4 and BLK with systemic lupus erythematosus and other rheumatic diseases."
    Tsuchiya N., Ito I., Kawasaki A.
    Nihon Rinsho Meneki Gakkai Kaishi 33:57-65(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: studies found that IRF5 STAT4 and BLK are associated not only with systemic lupus erythematosus but also rheumatoid arthritis and systemic sclerosis (review).
    Source: GeneRIF:640.

    This publication is mapped to 20 other entries.

  18. 18
    "Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients."
    Webb R., Kelly J.A., Somers E.C., Hughes T., Kaufman K.M., Sanchez E., Nath S.K., Bruner G., Alarcon-Riquelme M.E., Gilkeson G.S., Kamen D.L., Richardson B.C., Harley J.B., Sawalha A.H.
    Ann. Rheum. Dis. 70:151-156(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator).
    Source: GeneRIF:640.

    This publication is mapped to 117 other entries.

  19. 19
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:640.

    This publication is mapped to 226 other entries.

  20. 20
    "Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus."
    Orozco G., Eyre S., Hinks A., Bowes J., Morgan A.W., Wilson A.G., Wordsworth P., Steer S., Hocking L., Thomson W., Worthington J., Barton A.
    Ann. Rheum. Dis. 70:463-468(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study and meta-analysis of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:640.

    This publication is mapped to 42 other entries.

  21. 21
    "Association of BLK (rs13277113, rs2248932) polymorphism with systemic lupus erythematosus: a meta-analysis."
    Fan Y., Tao J.H., Zhang L.P., Li L.H., Ye D.Q.
    Mol. Biol. Rep. 38:4445-4453(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Moderate evidence exists for an association between the BLK rs13277113 rs2248932 variants and systemic lupus erythematosus.
    Source: GeneRIF:640.

    This publication is mapped to 2 other entries.

  22. 22
    Category: Interaction.
    Annotation: This study shows a genetic interaction between BANK1 and BLK and demonstrates that these molecules interact physically.
    Source: GeneRIF:640.

    This publication is mapped to 4 other entries.

  23. 23
    "Multifocal motor neuropathy is not associated with genetic variation in PTPN22, BANK1, Blk, FCGR2B, CD1A/E, and TAG-1 genes."
    Vlam L., Cats E.A., Seelen M., van Vught P.W., van den Berg L.H., van der Pol W.L.
    J. Peripher. Nerv. Syst. 16:175-179(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: allelic variation in Blk does not play a major role in determining multifocal motor neuropathy susceptibility.
    Source: GeneRIF:640.

    This publication is mapped to 30 other entries.

  24. 24
    "Identify the association between polymorphisms of BLK and systemic lupus erythematosus through unlabelled probe-based high-resolution melting analysis."
    Chen Y., Wu Q., Shao Y., Zhang J., Guan M., Wan J., Yu B., Zhang W.
    Int. J. Immunogenet. 39:321-327(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: The genetic variants in the promoter region of BLK may cause dysregulation of BLK expression which might finally contribute to the initiation and progression of systemic lupus erythematosus.
    Source: GeneRIF:640.

    This publication is mapped to 2 other entries.

  25. 25
    "The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development."
    Simpfendorfer K.R., Olsson L.M., Manjarrez Orduno N., Khalili H., Simeone A.M., Katz M.S., Lee A.T., Diamond B., Gregersen P.K.
    Hum. Mol. Genet. 21:3918-3925(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: Blk allele expression differences at the protein level are restricted to early B cells.
    Source: GeneRIF:640.

    This publication is mapped to 2 other entries.

1 to 25 of 54  Show
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