UniProtKB - Q05CH1 (Q05CH1_HUMAN)
Protein
Submitted name:
ARAP3 protein
Gene
ARAP3
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: ARAP3 proteinImportedSubmitted name: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3Imported |
Gene namesi | Name:ARAP3Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000120318.15 |
HGNCi | HGNC:24097, ARAP3 |
Expressioni
Gene expression databases
Bgeei | ENSG00000120318, Expressed in apex of heart and 199 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 8 – 68 | SAMInterPro annotationAdd BLAST | 61 | |
Domaini | 287 – 379 | PHInterPro annotationAdd BLAST | 93 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 64 – 147 | DisorderedSequence analysisAdd BLAST | 84 | |
Regioni | 167 – 194 | DisorderedSequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 84 – 98 | Pro-richSequence analysisAdd BLAST | 15 | |
Compositional biasi | 174 – 190 | PolarSequence analysisAdd BLAST | 17 |
Phylogenomic databases
GeneTreei | ENSGT00940000158869 |
HOGENOMi | CLU_578168_0_0_1 |
OrthoDBi | 98944at2759 |
Family and domain databases
Gene3Di | 1.10.150.50, 1 hit 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR001660, SAM IPR013761, SAM/pointed_sf |
Pfami | View protein in Pfam PF00169, PH, 1 hit PF07647, SAM_2, 1 hit |
SMARTi | View protein in SMART SM00233, PH, 2 hits SM00454, SAM, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit |
PROSITEi | View protein in PROSITE PS50003, PH_DOMAIN, 1 hit PS50105, SAM_DOMAIN, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q05CH1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAPQDLDIA VWLATVHLEQ YADTFRRHGL ATAGAARGLG HEELKQLGIS
60 70 80 90 100
ATGHRKRILR LLQTGTEEGS LDPKSDSAME PSPSPAPQAQ PPKPVPKPRT
110 120 130 140 150
VFGGLSGPAT TQRPGLSPAL GGPGVSRSPE PSPRPPPLPT SSSEQSSALN
160 170 180 190 200
TVEMMPNSIY FGLDSRGRAQ AAQDKAPDSS QISAPTPALR PTTGTVHIMD
210 220 230 240 250
PGCLYYGVQP VGTPGAPDRR ESRGVCQGRA EHRLSRQDLE AREDAGYASL
260 270 280 290 300
ELPGDSTLLS PTLETEETSD DLISPYASFS FTADRLTPLL SGWLDKLSPQ
310 320 330 340 350
GNYVFQRRFV QFNGRSLMYF GSDKDPFPKG VIPLTAIEMT RSSKDNKFQV
360 370 380 390 400
ITGQRVFVFR TESEAQRDMW CSTLQSCLKE QRLLGHPRPP QPPRPLRTGM
410 420 430 440 450
LELRGHKAKV FAALSPGELA LYKSEQAFSL GIGICFIELQ GCSVRETKSR
460 470
SFDLLTPHRC FSFTAESGGA RQS
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8WWN8 | ARAP3_HUMAN | Arf-GAP with Rho-GAP domain, ANK re... | ARAP3 CENTD3 | 1,544 | Annotation score: | ||
G5E9Y3 | G5E9Y3_HUMAN | Arf-GAP with Rho-GAP domain, ANK re... | ARAP3 CENTD3, hCG_1980706 | 1,375 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 473 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC022420 Genomic DNA No translation available. BC025757 mRNA Translation: AAH25757.1 |
RefSeqi | NP_071926.4, NM_022481.5 |
Genome annotation databases
Ensembli | ENST00000504448; ENSP00000421148; ENSG00000120318 |
GeneIDi | 64411 |
KEGGi | hsa:64411 |
UCSCi | uc063ics.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC022420 Genomic DNA No translation available. BC025757 mRNA Translation: AAH25757.1 |
RefSeqi | NP_071926.4, NM_022481.5 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | Q05CH1 |
PRIDEi | Q05CH1 |
ProteomicsDBi | 58389 |
Protocols and materials databases
Antibodypediai | 27363, 109 antibodies |
Genome annotation databases
Ensembli | ENST00000504448; ENSP00000421148; ENSG00000120318 |
GeneIDi | 64411 |
KEGGi | hsa:64411 |
UCSCi | uc063ics.1, human |
Organism-specific databases
CTDi | 64411 |
EuPathDBi | HostDB:ENSG00000120318.15 |
HGNCi | HGNC:24097, ARAP3 |
OpenTargetsi | ENSG00000120318 |
PharmGKBi | PA164715983 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158869 |
HOGENOMi | CLU_578168_0_0_1 |
OrthoDBi | 98944at2759 |
Miscellaneous databases
BioGRID-ORCSi | 64411, 4 hits in 842 CRISPR screens |
ChiTaRSi | ARAP3, human |
GenomeRNAii | 64411 |
Gene expression databases
Bgeei | ENSG00000120318, Expressed in apex of heart and 199 other tissues |
Family and domain databases
Gene3Di | 1.10.150.50, 1 hit 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR001660, SAM IPR013761, SAM/pointed_sf |
Pfami | View protein in Pfam PF00169, PH, 1 hit PF07647, SAM_2, 1 hit |
SMARTi | View protein in SMART SM00233, PH, 2 hits SM00454, SAM, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit |
PROSITEi | View protein in PROSITE PS50003, PH_DOMAIN, 1 hit PS50105, SAM_DOMAIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q05CH1_HUMAN | |
Accessioni | Q05CH1Primary (citable) accession number: Q05CH1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 14, 2006 |
Last sequence update: | November 14, 2006 | |
Last modified: | December 2, 2020 | |
This is version 125 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |