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UniProtKB - Q05854 (YL278_YEAST)
Protein
Uncharacterized transcriptional regulatory protein YLR278C
Gene
YLR278C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Miscellaneous
Present with 1080 molecules/cell in log phase SD medium.1 Publication
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 41 – 68 | Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST | 28 |
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- sequence-specific DNA binding Source: GO_Central
- zinc ion binding Source: InterPro
GO - Biological processi
- positive regulation of transcription by RNA polymerase II Source: GO_Central
- transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized transcriptional regulatory protein YLR278C |
Gene namesi | Ordered Locus Names:YLR278C ORF Names:L8003.10 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000004268, YLR278C |
VEuPathDBi | FungiDB:YLR278C |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000115003 | 1 – 1341 | Uncharacterized transcriptional regulatory protein YLR278CAdd BLAST | 1341 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1143 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
MaxQBi | Q05854 |
PaxDbi | Q05854 |
PRIDEi | Q05854 |
PTM databases
iPTMneti | Q05854 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 31546, 160 interactors |
DIPi | DIP-7433N |
IntActi | Q05854, 4 interactors |
MINTi | Q05854 |
STRINGi | 4932.YLR278C |
Miscellaneous databases
RNActi | Q05854, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 72 – 100 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 770 – 804 | DisorderedSequence analysisAdd BLAST | 35 | |
Regioni | 864 – 971 | DisorderedSequence analysisAdd BLAST | 108 | |
Regioni | 1031 – 1116 | DisorderedSequence analysisAdd BLAST | 86 | |
Regioni | 1220 – 1240 | DisorderedSequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 72 – 91 | Polar residuesSequence analysisAdd BLAST | 20 | |
Compositional biasi | 770 – 797 | Polar residuesSequence analysisAdd BLAST | 28 |
Phylogenomic databases
eggNOGi | ENOG502QS9Q, Eukaryota |
GeneTreei | ENSGT00940000176304 |
HOGENOMi | CLU_004038_1_0_1 |
InParanoidi | Q05854 |
OMAi | AHDMINN |
Family and domain databases
CDDi | cd00067, GAL4, 1 hit |
Gene3Di | 4.10.240.10, 1 hit |
InterProi | View protein in InterPro IPR007219, Transcription_factor_dom_fun IPR001138, Zn2-C6_fun-type_DNA-bd IPR036864, Zn2-C6_fun-type_DNA-bd_sf |
Pfami | View protein in Pfam PF04082, Fungal_trans, 1 hit PF00172, Zn_clus, 1 hit |
SMARTi | View protein in SMART SM00906, Fungal_trans, 1 hit SM00066, GAL4, 1 hit |
SUPFAMi | SSF57701, SSF57701, 1 hit |
PROSITEi | View protein in PROSITE PS00463, ZN2_CY6_FUNGAL_1, 1 hit PS50048, ZN2_CY6_FUNGAL_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q05854-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGRPRKNVSQ EKIQQLKREL ELAGNRTDVL LQDKKGRSRS CLLCRRRKQR
60 70 80 90 100
CDHKLPSCTA CLKAGIKCVQ PSKYSSSTSN SNTNNNTPTA GTVPPTPHPV
110 120 130 140 150
IKRELQDSSI GAGAGAATSL NDMTIIKPIS TSNSNVDAGD ANEFRKTIKS
160 170 180 190 200
VTTNSNPNLM RQDKDQYTIF LEKKLKSLET LLDLSPGCNQ YNYELSQYKK
210 220 230 240 250
VSHLFSNNTS DYSRPNSSNM VILPLPSPSN KPLENTNNNG SNVNAATNDT
260 270 280 290 300
SASTNNINNN NAICQSASLL NDPLETLDFT KCIFAKYNLK KEFLMYDPIF
310 320 330 340 350
ELNEKLSRSF LDTFFTRLQF KYPILDEQEI YTFYDHYLHN KILIPPSSPA
360 370 380 390 400
TSSAAPPSNS HSYSEIEFHF LSGRMWLVFS ISAYLLMTTG KYKGFPPHRY
410 420 430 440 450
FSTAIRHITK CGLHLNYVQQ IELLTLLVLY IIRTDRDSLI LYDIIKDVMG
460 470 480 490 500
ISKKKLHLNQ WYPNDPFANK KLRLFWCVYL LERMICVAVG KPYTIKESEI
510 520 530 540 550
NLPLFNNDSF YTKGVHAAAP STNDHGVQFI NQSLKLRRIE SQFVETLQLL
560 570 580 590 600
KNDSRSVKQS IDQLPLVRKF FEDLEVWRKS YSTLDVKNFE NETLKLYYYR
610 620 630 640 650
SVRLLIQPYL EFFAPEDRLF RECQAAAGQI CQLYKIFHQK TLNGHSTPAV
660 670 680 690 700
HTVFVAGVTL IYCMWLARNF DDQRRKKLGD ASKHTRPLIS ASLFSTMDDL
710 720 730 740 750
RACSVCLYVM TERSNFARTF RDTFDQLMNA TVGNLIERCG PDSSELIFMA
760 770 780 790 800
SSVAKRTEPK NINDEANKAI SSGDTLHDSN SANAANLSNS NDKNISHNGG
810 820 830 840 850
MPPAVARIFG KGQAEEHAGF VENSQVDLAE QEKFKKKQGV LEKTSVPKSL
860 870 880 890 900
AHLLTKMDDR SRISNSSMSY TTSSSSSSSS SSSSSTLSFP SSQEKNLKIN
910 920 930 940 950
VNNDNNGMTI SSVNREHNNN HNNNNDNNNN NNNNNNNSNN NNNVNNNDNE
960 970 980 990 1000
SNSRSTTNNS CNNGNNSQYV RNNNVTMEND VERPIQDQYI VKKPTNQTEF
1010 1020 1030 1040 1050
DWQVFQQQAF LQQQLAQHNL QAYLSSLNTD TMTNRSPSKS SSISTASSHS
1060 1070 1080 1090 1100
DPIPIAMTQS PTPYPQTSNM LPQQHVSRPL PQQQREQPQQ HITSPQRFSE
1110 1120 1130 1140 1150
SNFTNQLNNG MINSNPLQSA IFSNHTSENK QLRDVEESNF STSPLRADYG
1160 1170 1180 1190 1200
NNIISSIPAS FTSNSIPVSV KQARNGSSSG DILFSNGAHD MINNISTWTN
1210 1220 1230 1240 1250
NSVLDALNSK SILQTIFPQS QEPSSLSMDK QQQQHQQQNM CSENNVTANN
1260 1270 1280 1290 1300
FQQTQNDPSY NRNLFMMSNQ EGVQYNLDET EKNGPKTQVE ANTSANLHFD
1310 1320 1330 1340
NVIPTVTNAD IRKKRSNWDN MMTSGPVEDF WTINDDYGFL T
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U17243 Genomic DNA Translation: AAB67326.1 U17245 Genomic DNA Translation: AAB67370.1 BK006945 Genomic DNA Translation: DAA09591.1 |
PIRi | S50366 |
RefSeqi | NP_013380.1, NM_001182165.1 |
Genome annotation databases
EnsemblFungii | YLR278C_mRNA; YLR278C; YLR278C |
GeneIDi | 850984 |
KEGGi | sce:YLR278C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U17243 Genomic DNA Translation: AAB67326.1 U17245 Genomic DNA Translation: AAB67370.1 BK006945 Genomic DNA Translation: DAA09591.1 |
PIRi | S50366 |
RefSeqi | NP_013380.1, NM_001182165.1 |
3D structure databases
AlphaFoldDBi | Q05854 |
SMRi | Q05854 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 31546, 160 interactors |
DIPi | DIP-7433N |
IntActi | Q05854, 4 interactors |
MINTi | Q05854 |
STRINGi | 4932.YLR278C |
PTM databases
iPTMneti | Q05854 |
Proteomic databases
MaxQBi | Q05854 |
PaxDbi | Q05854 |
PRIDEi | Q05854 |
Genome annotation databases
EnsemblFungii | YLR278C_mRNA; YLR278C; YLR278C |
GeneIDi | 850984 |
KEGGi | sce:YLR278C |
Organism-specific databases
SGDi | S000004268, YLR278C |
VEuPathDBi | FungiDB:YLR278C |
Phylogenomic databases
eggNOGi | ENOG502QS9Q, Eukaryota |
GeneTreei | ENSGT00940000176304 |
HOGENOMi | CLU_004038_1_0_1 |
InParanoidi | Q05854 |
OMAi | AHDMINN |
Miscellaneous databases
PROi | PR:Q05854 |
RNActi | Q05854, protein |
Family and domain databases
CDDi | cd00067, GAL4, 1 hit |
Gene3Di | 4.10.240.10, 1 hit |
InterProi | View protein in InterPro IPR007219, Transcription_factor_dom_fun IPR001138, Zn2-C6_fun-type_DNA-bd IPR036864, Zn2-C6_fun-type_DNA-bd_sf |
Pfami | View protein in Pfam PF04082, Fungal_trans, 1 hit PF00172, Zn_clus, 1 hit |
SMARTi | View protein in SMART SM00906, Fungal_trans, 1 hit SM00066, GAL4, 1 hit |
SUPFAMi | SSF57701, SSF57701, 1 hit |
PROSITEi | View protein in PROSITE PS00463, ZN2_CY6_FUNGAL_1, 1 hit PS50048, ZN2_CY6_FUNGAL_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YL278_YEAST | |
Accessioni | Q05854Primary (citable) accession number: Q05854 Secondary accession number(s): D6VYS5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | May 25, 2022 | |
This is version 150 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XII
Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names