UniProtKB - Q05779 (COQ9_YEAST)
Protein
Ubiquinone biosynthesis protein COQ9, mitochondrial
Gene
COQ9
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.By similarity2 Publications
Miscellaneous
Present with 3420 molecules/cell in log phase SD medium.1 Publication
: ubiquinone biosynthesis Pathwayi
This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.1 PublicationView all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.
GO - Molecular functioni
- lipid binding Source: GO_Central
GO - Biological processi
- ubiquinone-6 biosynthetic process Source: SGD
- ubiquinone biosynthetic process Source: UniProtKB
Keywordsi
Biological process | Ubiquinone biosynthesis |
Ligand | Lipid-binding |
Enzyme and pathway databases
UniPathwayi | UPA00232 |
Names & Taxonomyi
Protein namesi | Recommended name: Ubiquinone biosynthesis protein COQ9, mitochondrial |
Gene namesi | Name:COQ9 Ordered Locus Names:YLR201C |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000004191, COQ9 |
VEuPathDBi | FungiDB:YLR201C |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane 3 Publications; Peripheral membrane protein 3 Publications; Matrix side 3 Publications
Mitochondrion
- mitochondrial inner membrane Source: SGD
- mitochondrion Source: SGD
Other locations
- protein-containing complex Source: UniProtKB
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 135 | L → E or K: Inability to grow on nonfermentable carbon sources. 1 Publication | 1 | |
Mutagenesisi | 174 | M → E: Impaired ability to grow on nonfermentable carbon sources. 1 Publication | 1 | |
Mutagenesisi | 185 | D → K: Inability to grow on nonfermentable carbon sources. 1 Publication | 1 | |
Mutagenesisi | 188 | W → K: Inability to grow on nonfermentable carbon sources. 1 Publication | 1 | |
Mutagenesisi | 189 | Y → D or K: Impaired ability to grow on nonfermentable carbon sources. 1 Publication | 1 | |
Mutagenesisi | 204 | L → K: Impaired ability to grow on nonfermentable carbon sources. 1 Publication | 1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – ? | MitochondrionSequence analysis | ||
ChainiPRO_0000227686 | ? – 260 | Ubiquinone biosynthesis protein COQ9, mitochondrial |
Proteomic databases
MaxQBi | Q05779 |
PaxDbi | Q05779 |
PRIDEi | Q05779 |
PTM databases
iPTMneti | Q05779 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 31470, 199 interactors |
ComplexPortali | CPX-1155, CoQ biosynthetic complex |
DIPi | DIP-3854N |
IntActi | Q05779, 6 interactors |
STRINGi | 4932.YLR201C |
Miscellaneous databases
RNActi | Q05779, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 189 – 192 | Lipid bindingBy similarity | 4 |
Sequence similaritiesi
Belongs to the COQ9 family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG2969, Eukaryota |
GeneTreei | ENSGT00390000009328 |
HOGENOMi | CLU_057411_1_1_1 |
InParanoidi | Q05779 |
OMAi | SELFMAQ |
Family and domain databases
InterProi | View protein in InterPro IPR013718, COQ9 IPR012762, Ubiq_biosynth_COQ9 |
PANTHERi | PTHR21427, PTHR21427, 1 hit |
Pfami | View protein in Pfam PF08511, COQ9, 1 hit |
TIGRFAMsi | TIGR02396, diverge_rpsU, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q05779-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLCRNTARTG CKFFRLYHSN PIEHVKPIHI KPLTYGKESP QYKVLSLALQ
60 70 80 90 100
KFVPEHGFSE RSIVESLNEL GYPSSMISSI GAPNSPSFFH SSTAVMELIK
110 120 130 140 150
FQLVDKRYRL TEGINPDVTP QYKLPSLEHL LLKRLEMDKP IGGHLSELMS
160 170 180 190 200
QLAIPSAFLF ETAIPELHRL SDDMIYFSNE KDHHDSAWYA KRLAVSSTYI
210 220 230 240 250
GSKLFMAQDK SHNYKETFTF AKDKLHRVMR LGEYYNNTEE FAWYTLMSTV
260
NLIKSQLVRG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U14913 Genomic DNA Translation: AAB67447.1 BK006945 Genomic DNA Translation: DAA09519.1 |
PIRi | S48553 |
RefSeqi | NP_013302.1, NM_001182088.1 |
Genome annotation databases
EnsemblFungii | YLR201C_mRNA; YLR201C; YLR201C |
GeneIDi | 850898 |
KEGGi | sce:YLR201C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U14913 Genomic DNA Translation: AAB67447.1 BK006945 Genomic DNA Translation: DAA09519.1 |
PIRi | S48553 |
RefSeqi | NP_013302.1, NM_001182088.1 |
3D structure databases
SMRi | Q05779 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 31470, 199 interactors |
ComplexPortali | CPX-1155, CoQ biosynthetic complex |
DIPi | DIP-3854N |
IntActi | Q05779, 6 interactors |
STRINGi | 4932.YLR201C |
PTM databases
iPTMneti | Q05779 |
Proteomic databases
MaxQBi | Q05779 |
PaxDbi | Q05779 |
PRIDEi | Q05779 |
Genome annotation databases
EnsemblFungii | YLR201C_mRNA; YLR201C; YLR201C |
GeneIDi | 850898 |
KEGGi | sce:YLR201C |
Organism-specific databases
SGDi | S000004191, COQ9 |
VEuPathDBi | FungiDB:YLR201C |
Phylogenomic databases
eggNOGi | KOG2969, Eukaryota |
GeneTreei | ENSGT00390000009328 |
HOGENOMi | CLU_057411_1_1_1 |
InParanoidi | Q05779 |
OMAi | SELFMAQ |
Enzyme and pathway databases
UniPathwayi | UPA00232 |
Miscellaneous databases
PROi | PR:Q05779 |
RNActi | Q05779, protein |
Family and domain databases
InterProi | View protein in InterPro IPR013718, COQ9 IPR012762, Ubiq_biosynth_COQ9 |
PANTHERi | PTHR21427, PTHR21427, 1 hit |
Pfami | View protein in Pfam PF08511, COQ9, 1 hit |
TIGRFAMsi | TIGR02396, diverge_rpsU, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | COQ9_YEAST | |
Accessioni | Q05779Primary (citable) accession number: Q05779 Secondary accession number(s): D6VYK3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 21, 2006 |
Last sequence update: | November 1, 1996 | |
Last modified: | February 10, 2021 | |
This is version 146 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XII
Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families