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UniProtKB - Q05110 (VA5_VESVU)
Protein
Venom allergen 5
Gene
N/A
Organism
Vespula vulgaris (Yellow jacket) (Wasp)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Venom allergen 5Alternative name(s): Allergen Ves v V Antigen 5 Short name: Ag5 Cysteine-rich venom protein Short name: CRVP Allergen: Ves v 5 |
Organismi | Vespula vulgaris (Yellow jacket) (Wasp) |
Taxonomic identifieri | 7454 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Hymenoptera › Apocrita › Aculeata › Vespoidea › Vespidae › Vespinae › Vespula |
Subcellular locationi
Extracellular region or secreted
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPathology & Biotechi
Allergenic propertiesi
Causes an allergic reaction in human.
Keywords - Diseasei
AllergenProtein family/group databases
Allergomei | 3523, Ves v 5.0101 670, Ves v 5 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Add BLAST | 23 | |
ChainiPRO_0000006297 | 24 – 227 | Venom allergen 5Add BLAST | 204 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 27 ↔ 40 | 1 Publication | ||
Disulfide bondi | 31 ↔ 124 | 1 Publication | ||
Disulfide bondi | 49 ↔ 117 | 1 Publication | ||
Disulfide bondi | 193 ↔ 210 | 1 Publication |
Keywords - PTMi
Disulfide bondExpressioni
Tissue specificityi
Expressed by the venom gland.
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q05110 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q05110 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 68 – 212 | SCPAdd BLAST | 145 |
Sequence similaritiesi
Keywords - Domaini
SignalFamily and domain databases
Gene3Di | 3.40.33.10, 1 hit |
InterProi | View protein in InterPro IPR018244, Allrgn_V5/Tpx1_CS IPR014044, CAP_domain IPR035940, CAP_sf IPR001283, CRISP-related IPR002413, V5_allergen-like |
PANTHERi | PTHR10334, PTHR10334, 1 hit |
Pfami | View protein in Pfam PF00188, CAP, 1 hit |
PRINTSi | PR00838, V5ALLERGEN PR00837, V5TPXLIKE |
SMARTi | View protein in SMART SM00198, SCP, 1 hit |
SUPFAMi | SSF55797, SSF55797, 1 hit |
PROSITEi | View protein in PROSITE PS01009, CRISP_1, 1 hit PS01010, CRISP_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q05110-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEISGLVYLI IIVTIIDLPY GKANNYCKIK CLKGGVHTAC KYGSLKPNCG
60 70 80 90 100
NKVVVSYGLT KQEKQDILKE HNDFRQKIAR GLETRGNPGP QPPAKNMKNL
110 120 130 140 150
VWNDELAYVA QVWANQCQYG HDTCRDVAKY QVGQNVALTG STAAKYDDPV
160 170 180 190 200
KLVKMWEDEV KDYNPKKKFS GNDFLKTGHY TQMVWANTKE VGCGSIKYIQ
210 220
EKWHKHYLVC NYGPSGNFMN EELYQTK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 109 | V → I in CAB42887 (Ref. 2) Curated | 1 | |
Sequence conflicti | 118 | Q → E in CAB42887 (Ref. 2) Curated | 1 | |
Sequence conflicti | 173 | D → N in CAB42887 (Ref. 2) Curated | 1 | |
Sequence conflicti | 219 | M → K in CAB42887 (Ref. 2) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M98858 mRNA Translation: AAA30333.1 AJ238849 Genomic DNA Translation: CAB42887.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M98858 mRNA Translation: AAA30333.1 AJ238849 Genomic DNA Translation: CAB42887.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1QNX | X-ray | 1.90 | A | 24-227 | [»] | |
SMRi | Q05110 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein family/group databases
Allergomei | 3523, Ves v 5.0101 670, Ves v 5 |
Miscellaneous databases
EvolutionaryTracei | Q05110 |
Family and domain databases
Gene3Di | 3.40.33.10, 1 hit |
InterProi | View protein in InterPro IPR018244, Allrgn_V5/Tpx1_CS IPR014044, CAP_domain IPR035940, CAP_sf IPR001283, CRISP-related IPR002413, V5_allergen-like |
PANTHERi | PTHR10334, PTHR10334, 1 hit |
Pfami | View protein in Pfam PF00188, CAP, 1 hit |
PRINTSi | PR00838, V5ALLERGEN PR00837, V5TPXLIKE |
SMARTi | View protein in SMART SM00198, SCP, 1 hit |
SUPFAMi | SSF55797, SSF55797, 1 hit |
PROSITEi | View protein in PROSITE PS01009, CRISP_1, 1 hit PS01010, CRISP_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | VA5_VESVU | |
Accessioni | Q05110Primary (citable) accession number: Q05110 Secondary accession number(s): Q9UB91 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1994 |
Last sequence update: | February 1, 1994 | |
Last modified: | June 2, 2021 | |
This is version 96 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencingDocuments
- Allergens
Nomenclature of allergens and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families