Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 147 (10 Apr 2019)
Sequence version 3 (16 Jun 2009)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Surfactin synthase subunit 2

Gene

srfAB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu, Glu, Asp and Val. Activation sites for these AA consist of individual domains.

Caution

The phosphoserine observed at Ser-999 and Ser-2040 in PubMed:17218307 may result from the secondary neutral loss of pantetheine from the phosphodiester linked cofactor.Curated

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pantetheine 4'-phosphateNote: Binds 3 phosphopantetheines covalently.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: surfactin biosynthesis

This protein is involved in the pathway surfactin biosynthesis, which is part of Antibiotic biosynthesis.
View all proteins of this organism that are known to be involved in the pathway surfactin biosynthesis and in Antibiotic biosynthesis.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLigase, Multifunctional enzyme
Biological processAntibiotic biosynthesis, Sporulation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BSUB:BSU03490-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00181

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Surfactin synthase subunit 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:srfAB
Synonyms:comL, srfA2
Ordered Locus Names:BSU03490
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus subtilis (strain 168)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224308 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001570 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001931001 – 3583Surfactin synthase subunit 2Add BLAST3583

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei999O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1 Publication1
Modified residuei2040O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1 Publication1
Modified residuei3069O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

Keywords - PTMi

Phosphopantetheine, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q04747

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q04747

PRoteomics IDEntifications database

More...
PRIDEi
Q04747

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q04747, 3 interactors

Molecular INTeraction database

More...
MINTi
Q04747

STRING: functional protein association networks

More...
STRINGi
224308.BSU03490

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q04747

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q04747

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini965 – 1039Carrier 1PROSITE-ProRule annotationAdd BLAST75
Domaini2005 – 2080Carrier 2PROSITE-ProRule annotationAdd BLAST76
Domaini3034 – 3108Carrier 3PROSITE-ProRule annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni? – 3110Domain 3 (D-leucine-activating)
Regioni? – 2091Domain 2 (aspartate-activating)
Regioni? – 1040Domain 1 (valine-activating)

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000229991

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q04747

KEGG Orthology (KO)

More...
KOi
K15655

Identification of Orthologs from Complete Genome Data

More...
OMAi
FNMQNME

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q04747

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 3 hits
3.30.559.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010071 AA_adenyl_domain
IPR036736 ACP-like_sf
IPR025110 AMP-bd_C
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_Synth/Lig
IPR023213 CAT-like_dom_sf
IPR001242 Condensatn
IPR010060 NRPS_synth
IPR020806 PKS_PP-bd
IPR009081 PP-bd_ACP
IPR006162 Ppantetheine_attach_site

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00501 AMP-binding, 3 hits
PF13193 AMP-binding_C, 3 hits
PF00668 Condensation, 4 hits
PF00550 PP-binding, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00823 PKS_PP, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336 SSF47336, 3 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01733 AA-adenyl-dom, 3 hits
TIGR01720 NRPS-para261, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00455 AMP_BINDING, 3 hits
PS50075 CARRIER, 3 hits
PS00012 PHOSPHOPANTETHEINE, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q04747-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKKSIQKVY ALTPMQEGML YHAMLDPHSS SYFTQLELGI HGAFDLEIFE
60 70 80 90 100
KSVNELIRSY DILRTVFVHQ QLQKPRQVVL AERKTKVHYE DISHADENRQ
110 120 130 140 150
KEHIERYKQD VQRQGFNLAK DILFKVAVFR LAADQLYLVW SNHHIMMDGW
160 170 180 190 200
SMGVLMKSLF QNYEALRAGR TPANGQGKPY SDYIKWLGKQ DNEEAESYWS
210 220 230 240 250
ERLAGFEQPS VLPGRLPVKK DEYVNKEYSF TWDETLVARI QQTANLHQVT
260 270 280 290 300
GPNLFQAVWG IVLSKYNFTD DVIFGTVVSG RPSEINGIET MAGLFINTIP
310 320 330 340 350
VRVKVERDAA FADIFTAVQQ HAVEAERYDY VPLYEIQKRS ALDGNLLNHL
360 370 380 390 400
VAFENYPLDQ ELENGSMEDR LGFSIKVESA FEQTSFDFNL IVYPGKTWTV
410 420 430 440 450
KIKYNGAAFD SAFIERTAEH LTRMMEAAVD QPAAFVREYG LVGDEEQRQI
460 470 480 490 500
VEVFNSTKAE LPEGMAVHQV FEEQAKRTPA STAVVYEGTK LTYRELNAAA
510 520 530 540 550
NRLARKLVEH GLQKGETAAI MNDRSVETVV GMLAVLKAGA AYVPLDPALP
560 570 580 590 600
GDRLRFMAED SSVRMVLIGN SYTGQAHQLQ VPVLTLDIGF EESEAADNLN
610 620 630 640 650
LPSAPSDLAY IMYTSGSTGK PKGVMIEHKS ILRLVKNAGY VPVTEEDRMA
660 670 680 690 700
QTGAVSFDAG TFEVFGALLN GAALYPVKKE TLLDAKQFAA FLREQSITTM
710 720 730 740 750
WLTSPLFNQL AAKDAGMFGT LRHLIIGGDA LVPHIVSKVK QASPSLSLWN
760 770 780 790 800
GYGPTENTTF STSFLIDREY GGSIPIGKPI GNSTAYIMDE QQCLQPIGAP
810 820 830 840 850
GELCVGGIGV ARGYVNLPEL TEKQFLEDPF RPGERIYRTG DLARWLPDGN
860 870 880 890 900
IEFLGRIDNQ VKVRGFRIEL GEIETKLNMA EHVTEAAVII RKNKADENEI
910 920 930 940 950
CAYFTADREV AVSELRKTLS QSLPDYMVPA HLIQMDSLPL TPNGKINKKE
960 970 980 990 1000
LPAPQSEAVQ PEYAAPKTES EKKLAEIWEG ILGVKAGVTD NFFMIGGHSL
1010 1020 1030 1040 1050
KAMMMTAKIQ EHFHKEVPIK VLFEKPTIQE LALYLEENES KEEQTFEPIR
1060 1070 1080 1090 1100
QASYQQHYPV SPAQRRMYIL NQLGQANTSY NVPAVLLLEG EVDKDRLENA
1110 1120 1130 1140 1150
IQQLINRHEI LRTSFDMIDG EVVQTVHKNI SFQLEAAKGR EEDAEEIIKA
1160 1170 1180 1190 1200
FVQPFELNRA PLVRSKLVQL EEKRHLLLID MHHIITDGSS TGILIGDLAK
1210 1220 1230 1240 1250
IYQGADLELP QIHYKDYAVW HKEQTNYQKD EEYWLDVFKG ELPILDLPAD
1260 1270 1280 1290 1300
FERPAERSFA GERVMFGLDK QITAQIKSLM AETDTTMYMF LLAAFNVLLS
1310 1320 1330 1340 1350
KYASQDDIIV GSPTAGRTHP DLQGVPGMFV NTVALRTAPA GDKTFAQFLE
1360 1370 1380 1390 1400
EVKTASLQAF EHQSYPLEEL IEKLPLTRDT SRSPLFSVMF NMQNMEIPSL
1410 1420 1430 1440 1450
RLGDLKISSY SMLHHVAKFD LSLEAVEREE DIGLSFDYAT ALFKDETIRR
1460 1470 1480 1490 1500
WSRHFVNIIK AAAANPNVRL SDVDLLSSAE TAALLEERHM TQITEATFAA
1510 1520 1530 1540 1550
LFEKQAQQTP DHSAVKAGGN LLTYRELDEQ ANQLAHHLRA QGAGNEDIVA
1560 1570 1580 1590 1600
IVMDRSAEVM VSILGVMKAG AAFLPIDPDT PEERIRYSLE DSGAKFAVVN
1610 1620 1630 1640 1650
ERNMTAIGQY EGIIVSLDDG KWRNESKERP SSISGSRNLA YVIYTSGTTG
1660 1670 1680 1690 1700
KPKGVQIEHR NLTNYVSWFS EEAGLTENDK TVLLSSYAFD LGYTSMFPVL
1710 1720 1730 1740 1750
LGGGELHIVQ KETYTAPDEI AHYIKEHGIT YIKLTPSLFH TIVNTASFAK
1760 1770 1780 1790 1800
DANFESLRLI VLGGEKIIPT DVIAFRKMYG HTEFINHYGP TEATIGAIAG
1810 1820 1830 1840 1850
RVDLYEPDAF AKRPTIGRPI ANAGALVLNE ALKLVPPGAS GQLYITGQGL
1860 1870 1880 1890 1900
ARGYLNRPQL TAERFVENPY SPGSLMYKTG DVVRRLSDGT LAFIGRADDQ
1910 1920 1930 1940 1950
VKIRGYRIEP KEIETVMLSL SGIQEAVVLA VSEGGLQELC AYYTSDQDIE
1960 1970 1980 1990 2000
KAELRYQLSL TLPSHMIPAF FVQVDAIPLT ANGKTDRNAL PKPNAAQSGG
2010 2020 2030 2040 2050
KALAAPETAL EESLCRIWQK TLGIEAIGID DNFFDLGGHS LKGMMLIANI
2060 2070 2080 2090 2100
QAELEKSVPL KALFEQPTVR QLAAYMEASA VSGGHQVLKP ADKQDMYPLS
2110 2120 2130 2140 2150
SAQKRMYVLN QLDRQTISYN MPSVLLMEGE LDISRLRDSL NQLVNRHESL
2160 2170 2180 2190 2200
RTSFMEANGE PVQRIIEKAE VDLHVFEAKE DEADQKIKEF IRPFDLNDAP
2210 2220 2230 2240 2250
LIRAALLRIE AKKHLLLLDM HHIIADGVSR GIFVKELALL YKGEQLPEPT
2260 2270 2280 2290 2300
LHYKDFAVWQ NEAEQKERMK EHEAYWMSVL SGELPELDLP LDYARPPVQS
2310 2320 2330 2340 2350
FKGDTIRFRT GSETAKAVEK LLAETGTTLH MVLHAVFHVF LSKISGQRDI
2360 2370 2380 2390 2400
VIGSVTAGRT NADVQDMPGM FVNTLALRME AKEQQTFAEL LELAKQTNLS
2410 2420 2430 2440 2450
ALEHQEYPFE DLVNQLDLPR DMSRNPLFNV MVTTENPDKE QLTLQNLSIS
2460 2470 2480 2490 2500
PYEAHQGTSK FDLTLGGFTD ENGIGLQLEY ATDLFAKETA EKWSEYVLRL
2510 2520 2530 2540 2550
LKAVADNPNQ PLSSLLLVTE TEKQALLEAW KGKALPVPTD KTVHQLFEET
2560 2570 2580 2590 2600
VQRHKDRPAV TYNGQSWTYG ELNAKANRLA RILMDCGISP DDRVGVLTKP
2610 2620 2630 2640 2650
SLEMSAAVLG VLKAGAAFVP IDPDYPDQRI EYILQDSGAK LLLKQEGISV
2660 2670 2680 2690 2700
PDSYTGDVIL LDGSRTILSL PLDENDEGNP ETAVTAENLA YMIYTSGTTG
2710 2720 2730 2740 2750
QPKGVMVEHH ALVNLCFWHH DAFSMTAEDR SAKYAGFGFD ASIWEMFPTW
2760 2770 2780 2790 2800
TIGAELHVID EAIRLDIVRL NDYFETNGVT ITFLPTQLAE QFMELENTSL
2810 2820 2830 2840 2850
RVLLTGGDKL KRAVKKPYTL VNNYGPTENT VVATSAEIHP EEGSLSIGRA
2860 2870 2880 2890 2900
IANTRVYILG EGNQVQPEGV AGELCVAGRG LARGYLNRED ETAKRFVADP
2910 2920 2930 2940 2950
FVPGERMYRT GDLVKWVNGG IEYIGRIDQQ VKVRGYRIEL SEIEVQLAQL
2960 2970 2980 2990 3000
SEVQDAAVTA VKDKGGNTAI AAYVTPETAD IEALKSTLKE TLPDYMIPAF
3010 3020 3030 3040 3050
WVTLNELPVT ANGKVDRKAL PEPDIEAGSG EYKAPTTDME ELLAGIWQDV
3060 3070 3080 3090 3100
LGMSEVGVTD NFFSLGGDSI KGIQMASRLN QHGWKLEMKD LFQHPTIEEL
3110 3120 3130 3140 3150
TQYVERAEGK QADQGPVEGE VILTPIQRWF FEKNFTNKHH WNQSVMLHAK
3160 3170 3180 3190 3200
KGFDPERVEK TLQALIEHHD ALRMVYREEN GDIVQVYKPI GESKVSFEIV
3210 3220 3230 3240 3250
DLYGSDEEML RSQIKLLANK LQSSLDLRNG PLLKAEQYRT EAGDHLLIAV
3260 3270 3280 3290 3300
HHLVVDGVSW RILLEDFASG YMQAEKEESL VFPQKTNSFK DWAEELAAFS
3310 3320 3330 3340 3350
QSAHLLQQAE YWSQIAAEQV SPLPKDCETE QRIVKDTSSV LCELTAEDTK
3360 3370 3380 3390 3400
HLLTDVHQPY GTEINDILLS ALGLTMKEWT KGAKIGINLE GHGREDIIPN
3410 3420 3430 3440 3450
VNISRTVGWF TAQYPVVLDI SDADASAVIK TVKENLRRIP DKGVGYGILR
3460 3470 3480 3490 3500
YFTETAETKG FTPEISFNYL GQFDSEVKTD FFEPSAFDMG RQVSGESEAL
3510 3520 3530 3540 3550
YALSFSGMIR NGRFVLSCSY NEKEFERATV EEQMERFKEN LLMLIRHCTE
3560 3570 3580
KEDKEFTPSD FSAEDLEMDE MGDIFDMLEE NLK
Length:3,583
Mass (Da):400,944
Last modified:June 16, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA257AC7643C4C64C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti33F → S in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti33F → S in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti42G → A in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti42G → A in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti110D → Q in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti110D → Q in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti113R → A in BAA02523 (PubMed:8441623).Curated1
Sequence conflicti115G → A in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti115G → A in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti139V → A in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti139V → A in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti259W → L in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti259W → L in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti309A → R in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti309A → R in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti478 – 480TPA → SRP in BAA02523 (PubMed:8441623).Curated3
Sequence conflicti507 – 513LVEHGLQ → ACRTRPS in CAA46678 (PubMed:1601288).Curated7
Sequence conflicti595Missing in CAA46678 (PubMed:1601288).Curated1
Sequence conflicti648R → A in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti648R → A in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti680 – 682ETL → RHV in CAA49817 (PubMed:8355609).Curated3
Sequence conflicti680 – 682ETL → RHV in BAA08983 (PubMed:8969502).Curated3
Sequence conflicti694 – 698EQSIT → DKRIS in CAA46678 (PubMed:1601288).Curated5
Sequence conflicti788M → L in CAA46678 (PubMed:1601288).Curated1
Sequence conflicti939 – 940PL → LV in BAA02523 (PubMed:8441623).Curated2
Sequence conflicti1038N → I in BAA02523 (PubMed:8441623).Curated1
Sequence conflicti1133Q → H in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti1133Q → H in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti1310V → C in BAA02523 (PubMed:8441623).Curated1
Sequence conflicti1333V → G in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti1333V → G in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti1384P → R in BAA02523 (PubMed:8441623).Curated1
Sequence conflicti1582E → G in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti1582E → G in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti1677E → KRRADG in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti1677E → KRRADG in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti1695S → C in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti1695S → C in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti1750K → F in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti1750K → F in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti1782T → S in BAA02523 (PubMed:8441623).Curated1
Sequence conflicti1796 – 1817GAIAG…RPTIG → APSPGGLICMSRCICETPDN R in BAA02523 (PubMed:8441623).CuratedAdd BLAST22
Sequence conflicti1910 – 1911PK → LG in CAA49817 (PubMed:8355609).Curated2
Sequence conflicti1910 – 1911PK → LG in BAA08983 (PubMed:8969502).Curated2
Sequence conflicti2070R → C in BAA02523 (PubMed:8441623).Curated1
Sequence conflicti2074A → V in BAA02523 (PubMed:8441623).Curated1
Sequence conflicti2134 – 2141SRLRDSLN → WPARLTP in CAA49817 (PubMed:8355609).Curated8
Sequence conflicti2134 – 2141SRLRDSLN → WPARLTP in BAA08983 (PubMed:8969502).Curated8
Sequence conflicti2134 – 2135SR → WP in BAA02523 (PubMed:8441623).Curated2
Sequence conflicti2441Q → E in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti2441Q → E in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti2481 – 2485ATDLF → RQICS in BAA02523 (PubMed:8441623).Curated5
Sequence conflicti2542 – 2562TVHQL…PAVTY → DGCISYSKRLSSATKTARLS HT in BAA02523 (PubMed:8441623).CuratedAdd BLAST21
Sequence conflicti2604 – 2611MSAAVLGV → KCPPRCSAS in BAA02523 (PubMed:8441623).Curated8
Sequence conflicti2640 – 2641KL → NV in BAA02523 (PubMed:8441623).Curated2
Sequence conflicti2709H → D in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti2709H → D in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti2719H → D in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti2719H → D in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti2872 – 2877GELCVA → RALRG in BAA02523 (PubMed:8441623).Curated6
Sequence conflicti2895 – 2896RF → L in BAA02523 (PubMed:8441623).Curated2
Sequence conflicti2954 – 2956QDA → EDR in CAA49817 (PubMed:8355609).Curated3
Sequence conflicti2954 – 2956QDA → EDR in BAA08983 (PubMed:8969502).Curated3
Sequence conflicti2960A → R in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti2960A → R in BAA08983 (PubMed:8969502).Curated1
Sequence conflicti3236 – 3237EQ → AE in CAA49817 (PubMed:8355609).Curated2
Sequence conflicti3236 – 3237EQ → AE in BAA08983 (PubMed:8969502).Curated2
Sequence conflicti3533Q → E in CAA49817 (PubMed:8355609).Curated1
Sequence conflicti3533Q → E in BAA08983 (PubMed:8969502).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D13262 Genomic DNA Translation: BAA02523.1
X70356 Genomic DNA Translation: CAA49817.1
D50453 Genomic DNA Translation: BAA08983.1
AL009126 Genomic DNA Translation: CAB12143.2
X65835 Genomic DNA Translation: CAA46678.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I40486

NCBI Reference Sequences

More...
RefSeqi
NP_388231.2, NC_000964.3
WP_010886403.1, NZ_CP019663.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CAB12143; CAB12143; BSU03490

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
938303

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bsu:BSU03490

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|224308.179.peg.367

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13262 Genomic DNA Translation: BAA02523.1
X70356 Genomic DNA Translation: CAA49817.1
D50453 Genomic DNA Translation: BAA08983.1
AL009126 Genomic DNA Translation: CAB12143.2
X65835 Genomic DNA Translation: CAA46678.1
PIRiI40486
RefSeqiNP_388231.2, NC_000964.3
WP_010886403.1, NZ_CP019663.1

3D structure databases

ProteinModelPortaliQ04747
SMRiQ04747
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ04747, 3 interactors
MINTiQ04747
STRINGi224308.BSU03490

Proteomic databases

jPOSTiQ04747
PaxDbiQ04747
PRIDEiQ04747

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12143; CAB12143; BSU03490
GeneIDi938303
KEGGibsu:BSU03490
PATRICifig|224308.179.peg.367

Phylogenomic databases

HOGENOMiHOG000229991
InParanoidiQ04747
KOiK15655
OMAiFNMQNME
PhylomeDBiQ04747

Enzyme and pathway databases

UniPathwayi
UPA00181

BioCyciBSUB:BSU03490-MONOMER

Family and domain databases

Gene3Di1.10.1200.10, 3 hits
3.30.559.10, 4 hits
InterProiView protein in InterPro
IPR010071 AA_adenyl_domain
IPR036736 ACP-like_sf
IPR025110 AMP-bd_C
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_Synth/Lig
IPR023213 CAT-like_dom_sf
IPR001242 Condensatn
IPR010060 NRPS_synth
IPR020806 PKS_PP-bd
IPR009081 PP-bd_ACP
IPR006162 Ppantetheine_attach_site
PfamiView protein in Pfam
PF00501 AMP-binding, 3 hits
PF13193 AMP-binding_C, 3 hits
PF00668 Condensation, 4 hits
PF00550 PP-binding, 3 hits
SMARTiView protein in SMART
SM00823 PKS_PP, 3 hits
SUPFAMiSSF47336 SSF47336, 3 hits
TIGRFAMsiTIGR01733 AA-adenyl-dom, 3 hits
TIGR01720 NRPS-para261, 1 hit
PROSITEiView protein in PROSITE
PS00455 AMP_BINDING, 3 hits
PS50075 CARRIER, 3 hits
PS00012 PHOSPHOPANTETHEINE, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSRFAB_BACSU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q04747
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: June 16, 2009
Last modified: April 10, 2019
This is version 147 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again