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Entry version 160 (26 Feb 2020)
Sequence version 4 (26 Feb 2008)
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Protein

Ring canal kelch protein

Gene

kel

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of ring canals that regulates the flow of cytoplasm between cells. May be involved in the regulation of cytoplasm flow from nurse cells to the oocyte during oogenesis. Binds actin.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin binding Source: FlyBase

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding, Developmental protein
Biological processDifferentiation, Oogenesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-8951664 Neddylation
R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ring canal kelch protein
Cleaved into the following chain:
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:kel
ORF Names:CG7210
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0001301 kel

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000166511 – 1477Ring canal kelch proteinAdd BLAST1477
ChainiPRO_00000166521 – 689Kelch short proteinAdd BLAST689

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei108Phosphoserine1 Publication1
Modified residuei111Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q04652

PRoteomics IDEntifications database

More...
PRIDEi
Q04652

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q04652

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Both proteins are expressed in ovaries, male testis, ovariectomized females, cuticle, salivary gland and imaginal disks. Kelch short protein is the predominant form and is also expressed in fat bodies. On entry into metamorphosis levels of full-length protein increase in testis and imaginal disks.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Larvae, pupae and adults.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0001301 Expressed in embryo and 17 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q04652 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
61080, 10 interactors

Protein interaction database and analysis system

More...
IntActi
Q04652, 2 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0080595

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q04652

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini157 – 223BTBPROSITE-ProRule annotationAdd BLAST67
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati404 – 449Kelch 1Add BLAST46
Repeati450 – 496Kelch 2Add BLAST47
Repeati498 – 543Kelch 3Add BLAST46
Repeati545 – 592Kelch 4Add BLAST48
Repeati594 – 639Kelch 5Add BLAST46
Repeati641 – 687Kelch 6Add BLAST47

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi18 – 28Asn-richAdd BLAST11
Compositional biasi29 – 87Gln-richAdd BLAST59
Compositional biasi29 – 36Poly-Gln8
Compositional biasi78 – 83Poly-Gln6

Keywords - Domaini

Kelch repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4441 Eukaryota
ENOG410XNX8 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004193_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q04652

KEGG Orthology (KO)

More...
KOi
K10443

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.120.10.80, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011705 BACK
IPR000210 BTB/POZ_dom
IPR015915 Kelch-typ_b-propeller
IPR006652 Kelch_1
IPR011333 SKP1/BTB/POZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07707 BACK, 1 hit
PF00651 BTB, 1 hit
PF01344 Kelch_1, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00875 BACK, 1 hit
SM00225 BTB, 1 hit
SM00612 Kelch, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF117281 SSF117281, 1 hit
SSF54695 SSF54695, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50097 BTB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q04652-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIALSALLTK YTIGIMSNLS NGNSNNNNQQ QQQQQQGQNP QQPAQNEGGA
60 70 80 90 100
GAEFVAPPPG LGAAVGVAAM QQRNRLLQQQ QQQHHHHQNP AAEGSGLERG
110 120 130 140 150
SCLLRYASQN SLDESSQKHV QRPNGKERGT VGQYSNEQHT ARSFDAMNEM
160 170 180 190 200
RKQKQLCDVI LVADDVEIHA HRMVLASCSP YFYAMFTSFE ESRQARITLQ
210 220 230 240 250
SVDARALELL IDYVYTATVE VNEDNVQVLL TAANLLQLTD VRDACCDFLQ
260 270 280 290 300
TQLDASNCLG IREFADIHAC VELLNYAETY IEQHFNEVIQ FDEFLNLSHE
310 320 330 340 350
QVISLIGNDR ISVPNEERVY ECVIAWLRYD VPMREQFTSL LMEHVRLPFL
360 370 380 390 400
SKEYITQRVD KEILLEGNIV CKNLIIEALT YHLLPTETKS ARTVPRKPVG
410 420 430 440 450
MPKILLVIGG QAPKAIRSVE WYDLREEKWY QAAEMPNRRC RSGLSVLGDK
460 470 480 490 500
VYAVGGFNGS LRVRTVDVYD PATDQWANCS NMEARRSTLG VAVLNGCIYA
510 520 530 540 550
VGGFDGTTGL SSAEMYDPKT DIWRFIASMS TRRSSVGVGV VHGLLYAVGG
560 570 580 590 600
YDGFTRQCLS SVERYNPDTD TWVNVAEMSS RRSGAGVGVL NNILYAVGGH
610 620 630 640 650
DGPMVRRSVE AYDCETNSWR SVADMSYCRR NAGVVAHDGL LYVVGGDDGT
660 670 680 690 700
SNLASVEVYC PDSDSWRILP ALMTIGRSYA GVCMIDKPMU MEEQGALARQ
710 720 730 740 750
AASLAIALLD DENSQAEGTM EGAIGGAIYG NLAPAGGAAA AAAPAAPAQA
760 770 780 790 800
PQPNHPHYEN IYAPIGQPSN NNNNSGSNSN QAAAIANANA PANAEEIQQQ
810 820 830 840 850
QQPAPTEPNA NNNPQPPTAA APAPSQQQQQ QQAQPQQPQR ILPMNNYRND
860 870 880 890 900
LYDRSAAGGV CSAYDVPRAV RSGLGYRRNF RIDMQNGNRC GSGLRCTPLY
910 920 930 940 950
TNSRSNCQRQ RSFDDTESTD GYNLPYAGAG TMRYENIYEQ IRDEPLYRTS
960 970 980 990 1000
AANRVPLYTR LDVLGHGIGR IERHLSSSCG NIDHYNLGGH YAVLGHSHFG
1010 1020 1030 1040 1050
TVGHIRLNAN GSGVAAPGVA GTGTCNVPNC QGYMTAAGST VPVEYANVKV
1060 1070 1080 1090 1100
PVKNSASSFF SCLHGENSQS MTNIYKTSGT AAAMAAHNSP LTPNVSMERA
1110 1120 1130 1140 1150
SRSASAGAAG SAAAAVEEHS AADSIPSSSN INANRTTGAI PKVKTANKPA
1160 1170 1180 1190 1200
KESGGSSTAA SPILDKTTST GSGKSVTLAK KTSTAAARSS SSGDTNGNGT
1210 1220 1230 1240 1250
LNRISKSSLQ WLLVNKWLPL WIGQGPDCKV IDFNFMFSRD CVSCDTASVA
1260 1270 1280 1290 1300
SQMSNPYGTP RLSGLPQDMV RFQSSCAGAC AAAGAASTIR RDANASARPL
1310 1320 1330 1340 1350
HSTLSRLRNG EKRNPNRVAG NYQYEDPSYE NVHVQWQNGF EFGRSRDYDP
1360 1370 1380 1390 1400
NSTYHQQRPL LQRARSESPT FSNQQRRLQR QGAQAQQQSQ QPKPPGSPDP
1410 1420 1430 1440 1450
YKNYKLNADN NTFKPKPIAA DELEGAVGGA VAEIALPEVD IEVVDPVSLS
1460 1470
DNETETTSSQ NNLPSTTNSN NLNEHND
Length:1,477
Mass (Da):160,133
Last modified:February 26, 2008 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1125703128F2BCCD
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence ADZ05867 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti493V → A in AAA53471 (PubMed:8453663).Curated1
Sequence conflicti493V → A in AAA53472 (PubMed:8453663).Curated1
Sequence conflicti596A → R in AAA53471 (PubMed:8453663).Curated1
Sequence conflicti596A → R in AAA53472 (PubMed:8453663).Curated1
Sequence conflicti824P → L in AAA53472 (PubMed:8453663).Curated1
Sequence conflicti858G → D in AAA53472 (PubMed:8453663).Curated1
Sequence conflicti1083A → R in AAA53472 (PubMed:8453663).Curated1
Sequence conflicti1086A → G in AAA53472 (PubMed:8453663).Curated1

Non-standard residue

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the occurrence of non-standard amino acids selenocysteine (Sec) or pyrrolysine (Pyl) in the protein sequence.<p><a href='/help/non_std' target='_top'>More...</a></p>Non-standard residuei690SelenocysteineCurated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L08483 mRNA Translation: AAA53471.1
L08483 mRNA Translation: AAA53472.2
AE014134 Genomic DNA Translation: AAF53651.1
AE014134 Genomic DNA Translation: AAN11182.3
BT003250 mRNA Translation: ADZ05867.1 Sequence problems.

Protein sequence database of the Protein Information Resource

More...
PIRi
A45773

NCBI Reference Sequences

More...
RefSeqi
NP_476589.4, NM_057241.3
NP_724095.1, NM_165242.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
35084

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG7210

UCSC genome browser

More...
UCSCi
CG7210-RA d. melanogaster

Keywords - Coding sequence diversityi

Selenocysteine

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L08483 mRNA Translation: AAA53471.1
L08483 mRNA Translation: AAA53472.2
AE014134 Genomic DNA Translation: AAF53651.1
AE014134 Genomic DNA Translation: AAN11182.3
BT003250 mRNA Translation: ADZ05867.1 Sequence problems.
PIRiA45773
RefSeqiNP_476589.4, NM_057241.3
NP_724095.1, NM_165242.2

3D structure databases

SMRiQ04652
ModBaseiSearch...

Protein-protein interaction databases

BioGridi61080, 10 interactors
IntActiQ04652, 2 interactors
STRINGi7227.FBpp0080595

PTM databases

iPTMnetiQ04652

Proteomic databases

PaxDbiQ04652
PRIDEiQ04652

Genome annotation databases

GeneIDi35084
KEGGidme:Dmel_CG7210
UCSCiCG7210-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3792
FlyBaseiFBgn0001301 kel

Phylogenomic databases

eggNOGiKOG4441 Eukaryota
ENOG410XNX8 LUCA
HOGENOMiCLU_004193_1_0_1
InParanoidiQ04652
KOiK10443

Enzyme and pathway databases

ReactomeiR-DME-8951664 Neddylation
R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
kel fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
35084

Protein Ontology

More...
PROi
PR:Q04652

Gene expression databases

BgeeiFBgn0001301 Expressed in embryo and 17 other tissues
GenevisibleiQ04652 DM

Family and domain databases

Gene3Di2.120.10.80, 1 hit
InterProiView protein in InterPro
IPR011705 BACK
IPR000210 BTB/POZ_dom
IPR015915 Kelch-typ_b-propeller
IPR006652 Kelch_1
IPR011333 SKP1/BTB/POZ_sf
PfamiView protein in Pfam
PF07707 BACK, 1 hit
PF00651 BTB, 1 hit
PF01344 Kelch_1, 6 hits
SMARTiView protein in SMART
SM00875 BACK, 1 hit
SM00225 BTB, 1 hit
SM00612 Kelch, 6 hits
SUPFAMiSSF117281 SSF117281, 1 hit
SSF54695 SSF54695, 1 hit
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKELC_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q04652
Secondary accession number(s): F0JAF0
, Q04653, Q86PA7, Q9VJA2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 26, 2008
Last modified: February 26, 2020
This is version 160 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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