Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein-glutamate O-methyltransferase

Gene

YMR027W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

O-methyltransferase that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues.By similarity

Miscellaneous

Present with 6190 molecules/cell in log phase SD medium.1 Publication

Catalytic activityi

S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate methyl ester.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei259S-adenosyl-L-methionineBy similarity1
Binding sitei292S-adenosyl-L-methionineBy similarity1

GO - Molecular functioni

  • methyltransferase activity Source: UniProtKB-KW
  • phosphatase activity Source: SGD

Keywordsi

Molecular functionMethyltransferase, Transferase
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciYEAST:G3O-32732-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-glutamate O-methyltransferaseBy similarity (EC:2.1.1.-By similarity)
Gene namesi
Ordered Locus Names:YMR027W
ORF Names:YM9711.17
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR027W
SGDiS000004629 YMR027W

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002032711 – 470Protein-glutamate O-methyltransferaseAdd BLAST470

Proteomic databases

MaxQBiQ04371
PaxDbiQ04371
PRIDEiQ04371

Interactioni

Protein-protein interaction databases

BioGridi35199, 41 interactors
IntActiQ04371, 3 interactors
MINTiQ04371
STRINGi4932.YMR027W

Structurei

Secondary structure

1470
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ04371
SMRiQ04371
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ARMT1 family.Curated

Phylogenomic databases

GeneTreeiENSGT00530000064023
HOGENOMiHOG000172710
InParanoidiQ04371
OMAiRHNERNS
OrthoDBiEOG092C2H3M

Family and domain databases

InterProiView protein in InterPro
IPR036075 AF1104-like_sf
IPR002791 DUF89
PfamiView protein in Pfam
PF01937 DUF89, 1 hit
SUPFAMiSSF111321 SSF111321, 2 hits

Sequencei

Sequence statusi: Complete.

Q04371-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIPGRFMTI DKGTFGEYTA STRWPIIIQN AIDDLSKHQE TEKSNGTKFE
60 70 80 90 100
QGEVIKKELK EFRQEIIDRV PLRPFTEEEI KIANVPLSFN EYLKKHPEVN
110 120 130 140 150
WGAVEWLFSE VYLYRRVNVL FQRQCEWAKF DIFNRLKQST FESSFYGVVE
160 170 180 190 200
LALRYENLLP QLREMKQNPG NEIDDILKVL FKEFIEISLW GNATDLSLLT
210 220 230 240 250
NATLEDIKSI QGAKARAASE SKIVVNDTEK AWEVLTKARA DANSREIRVD
260 270 280 290 300
FVLDNSGFEL YADLMLAAFL LQSGLATKCI FHAKDIPYMV SDVMLKDFDI
310 320 330 340 350
LVHDLRDREF FPSGEPSTKE SRALDLFAGE MEKFVSSGKI EFREDSFWTT
360 370 380 390 400
ELDYWNLDAN ETKYHGSILH KDLQKSNLVI FKGDLNYRKL TGDRKWPRTT
410 420 430 440 450
KWETAIGPLA TNGITSLSLR TCKADVQVAL PEGLDAKLSQ EWEKENPGRG
460 470
SWWCCSGKWA VICFCSGIHK
Length:470
Mass (Da):54,129
Last modified:November 1, 1997 - v1
Checksum:iC71DC2833CF85D5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49211 Genomic DNA Translation: CAA89130.1
BK006946 Genomic DNA Translation: DAA09925.1
PIRiS54029
RefSeqiNP_013740.1, NM_001182523.1

Genome annotation databases

EnsemblFungiiYMR027W; YMR027W; YMR027W
GeneIDi855042
KEGGisce:YMR027W

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49211 Genomic DNA Translation: CAA89130.1
BK006946 Genomic DNA Translation: DAA09925.1
PIRiS54029
RefSeqiNP_013740.1, NM_001182523.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3PT1X-ray1.77A1-470[»]
5BY0X-ray1.80A1-470[»]
5F13X-ray2.39A/B/C1-470[»]
ProteinModelPortaliQ04371
SMRiQ04371
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35199, 41 interactors
IntActiQ04371, 3 interactors
MINTiQ04371
STRINGi4932.YMR027W

Proteomic databases

MaxQBiQ04371
PaxDbiQ04371
PRIDEiQ04371

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYMR027W; YMR027W; YMR027W
GeneIDi855042
KEGGisce:YMR027W

Organism-specific databases

EuPathDBiFungiDB:YMR027W
SGDiS000004629 YMR027W

Phylogenomic databases

GeneTreeiENSGT00530000064023
HOGENOMiHOG000172710
InParanoidiQ04371
OMAiRHNERNS
OrthoDBiEOG092C2H3M

Enzyme and pathway databases

BioCyciYEAST:G3O-32732-MONOMER

Miscellaneous databases

PROiPR:Q04371

Family and domain databases

InterProiView protein in InterPro
IPR036075 AF1104-like_sf
IPR002791 DUF89
PfamiView protein in Pfam
PF01937 DUF89, 1 hit
SUPFAMiSSF111321 SSF111321, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiARMT1_YEAST
AccessioniPrimary (citable) accession number: Q04371
Secondary accession number(s): D6VZK1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: September 12, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again