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Entry version 144 (02 Jun 2021)
Sequence version 1 (01 Nov 1997)
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Protein

Uncharacterized protein YMR196W

Gene

YMR196W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Present with 2220 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein YMR196W
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:YMR196W
ORF Names:YM9646.09
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XIII

Organism-specific databases

Saccharomyces Genome Database

More...
SGDi
S000004809, YMR196W

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:YMR196W

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002033261 – 1088Uncharacterized protein YMR196WAdd BLAST1088

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei299PhosphoserineCombined sources1
Modified residuei984PhosphoserineCombined sources1
Modified residuei1013PhosphothreonineCombined sources1
Modified residuei1081PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q04336

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q04336

PRoteomics IDEntifications database

More...
PRIDEi
Q04336

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q04336

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
35374, 64 interactors

Database of interacting proteins

More...
DIPi
DIP-6550N

Protein interaction database and analysis system

More...
IntActi
Q04336, 6 interactors

Molecular INTeraction database

More...
MINTi
Q04336

STRING: functional protein association networks

More...
STRINGi
4932.YMR196W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q04336, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni954 – 980DisorderedSequence analysisAdd BLAST27
Regioni1063 – 1088DisorderedSequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi954 – 970Polar residuesSequence analysisAdd BLAST17
Compositional biasi1063 – 1079Basic and acidic residuesSequence analysisAdd BLAST17

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2161, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017452

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005386_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q04336

Identification of Orthologs from Complete Genome Data

More...
OMAi
NCRLPQT

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.50.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008928, 6-hairpin_glycosidase_sf
IPR012341, 6hp_glycosidase-like_sf
IPR004888, Glycoside_hydrolase_63

The PANTHER Classification System

More...
PANTHERi
PTHR10412, PTHR10412, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48208, SSF48208, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q04336-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNKLRDKFVD STVEEERLRE NRNHEKYWYR WGPYLSERSW ATVREDYSLN
60 70 80 90 100
GDAWSNFPFE HANARVFRWG EDGLFGVSDN KQLVCMNVAL WNGKDERLKE
110 120 130 140 150
RLFGLTGPQG NHGEDVKELY FYLDNTPTHS YMKALYKYPF KKAFPYKELV
160 170 180 190 200
QKNGERGYED KEFEVYDIDG LYRDSETGDN PYFDVFFEMA KDDENPSELN
210 220 230 240 250
FRLTIHNRSK IDSGELYIAP QLFFRNTWAF DGTRTKDKPL LERDAEAANL
260 270 280 290 300
INMTHKKYGN CQMVFQPSPG GFSSGTNEEE EDKEVEDIDP LLLFTDNESN
310 320 330 340 350
LVKLFNEEKN PSEYTKDAFE EYLVQGKTDA VNPENKGTKA CAVYHFKNIP
360 370 380 390 400
PGEYVTVRYK FTNDPKNSIF KAQNLAVVDE DEFDLIFDNR EEEADNFYWR
410 420 430 440 450
ITPLPISDEL RNLQRQAFSG LLWTKQFYNF TYDAWYNGDA NVKPRPPPNR
460 470 480 490 500
ANGRNKNWKH LYIEDILSMP DKWEYPFFAS WDTAFHCIPL AMIDPEFAKR
510 520 530 540 550
QLDLLTREWY MHPNGQIPAY EWNFNDVNPP VHAWAVYRVF KIERNMYNRE
560 570 580 590 600
DRTFLERVFQ KLLLNFTWWV NRKDTEGKNV FEGGFLGLDN IGVFNRSEPL
610 620 630 640 650
PTGGTLEQAD STGWMAFFSL QMLNIALELA KENPVYEDIA SKFFEHFILI
660 670 680 690 700
SDSMSFEYAT DITGEKCKEV IKQNLWNEAD KFYYDAISWG DHKVQLPIRS
710 720 730 740 750
LVGLIPLYAS MTLEPSIIKQ FRGFKKRVDW FVNNRPEIFD RNIASMSKKG
760 770 780 790 800
VGERLLLSLV TKERLTAILS RLLDETEFLS PYGIRSLSKY HEKHPFEMNV
810 820 830 840 850
NGVEYMVKYL PGESDSGMFG GNSNWRGPIW FPTSFLIMEA LQRFYLYYGS
860 870 880 890 900
DFKVECPVGS GDYLNLAEVA EELGYRMIHL FVPDENGERA IHYGDHSKFL
910 920 930 940 950
SSDPYFRDYV PFFEYFDGDT GRGLGASHQC GWTALVAKWI SDVGISCVRL
960 970 980 990 1000
PRTPRSSVAT TASTESSEQG PKMKRMARRK SAKSLVNYTA TILDLTEEEK
1010 1020 1030 1040 1050
RHHRIGGTHS GLTPQSSISS DKARHLMEEM NEEEGIHETV VPEDRHNFET
1060 1070 1080
KLIGKLKDKV KNMKVTDKAK DEDIDPMDPM SPLNKDVS
Length:1,088
Mass (Da):126,624
Last modified:November 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i36C2B42BB2749687
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z47815 Genomic DNA Translation: CAA87818.1
BK006946 Genomic DNA Translation: DAA10095.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S50925

NCBI Reference Sequences

More...
RefSeqi
NP_013923.1, NM_001182703.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YMR196W_mRNA; YMR196W; YMR196W

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
855236

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YMR196W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z47815 Genomic DNA Translation: CAA87818.1
BK006946 Genomic DNA Translation: DAA10095.1
PIRiS50925
RefSeqiNP_013923.1, NM_001182703.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi35374, 64 interactors
DIPiDIP-6550N
IntActiQ04336, 6 interactors
MINTiQ04336
STRINGi4932.YMR196W

PTM databases

iPTMnetiQ04336

Proteomic databases

MaxQBiQ04336
PaxDbiQ04336
PRIDEiQ04336

Genome annotation databases

EnsemblFungiiYMR196W_mRNA; YMR196W; YMR196W
GeneIDi855236
KEGGisce:YMR196W

Organism-specific databases

SGDiS000004809, YMR196W
VEuPathDBiFungiDB:YMR196W

Phylogenomic databases

eggNOGiKOG2161, Eukaryota
GeneTreeiENSGT00390000017452
HOGENOMiCLU_005386_0_1_1
InParanoidiQ04336
OMAiNCRLPQT

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q04336
RNActiQ04336, protein

Family and domain databases

Gene3Di1.50.10.10, 2 hits
InterProiView protein in InterPro
IPR008928, 6-hairpin_glycosidase_sf
IPR012341, 6hp_glycosidase-like_sf
IPR004888, Glycoside_hydrolase_63
PANTHERiPTHR10412, PTHR10412, 1 hit
SUPFAMiSSF48208, SSF48208, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYM54_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q04336
Secondary accession number(s): D6W021
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 2, 2021
This is version 144 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names
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