The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - Q04210 (YET2_YEAST)
Protein
Endoplasmic reticulum transmembrane protein 2
Gene
YET2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
1 PublicationGO - Biological processi
- endoplasmic reticulum to Golgi vesicle-mediated transport Source: GO_Central
- intracellular protein transport Source: InterPro
- protein localization to endoplasmic reticulum exit site Source: GO_Central
Keywordsi
Biological process | ER-Golgi transport, Protein transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Endoplasmic reticulum transmembrane protein 2 |
Gene namesi | Name:YET2 Ordered Locus Names:YMR040W ORF Names:YM9532.05 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000004643, YET2 |
VEuPathDBi | FungiDB:YMR040W |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane By similarity; Multi-pass membrane protein By similarity
Endoplasmic reticulum
- endoplasmic reticulum Source: SGD
- endoplasmic reticulum membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 2 | LumenalSequence analysis | 2 | |
Transmembranei | 3 – 23 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 24 – 45 | CytoplasmicSequence analysisAdd BLAST | 22 | |
Transmembranei | 46 – 66 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 67 – 103 | LumenalSequence analysisAdd BLAST | 37 | |
Transmembranei | 104 – 124 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 125 – 160 | CytoplasmicSequence analysisAdd BLAST | 36 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000203275 | 1 – 160 | Endoplasmic reticulum transmembrane protein 2Add BLAST | 160 |
Proteomic databases
PaxDbi | Q04210 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 35212, 53 interactors |
STRINGi | 4932.YMR040W |
Miscellaneous databases
RNActi | Q04210, protein |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 157 – 160 | Di-lysine motif | 4 |
Domaini
The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.By similarity
Sequence similaritiesi
Belongs to the BCAP29/BCAP31 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1962, Eukaryota |
GeneTreei | ENSGT00390000011863 |
HOGENOMi | CLU_087648_1_0_1 |
InParanoidi | Q04210 |
OMAi | EMAILFI |
Family and domain databases
InterProi | View protein in InterPro IPR008417, BAP29/BAP31 IPR040463, BAP29/BAP31_N |
PANTHERi | PTHR12701, PTHR12701, 1 hit |
Pfami | View protein in Pfam PF05529, Bap31, 1 hit |
i Sequence
Sequence statusi: Complete.
Q04210-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGVYLAVLFS LLVIEMAILF ILVLPLPQRM RRWLYIRYSI ISTNKKFRTY
60 70 80 90 100
MVGIMIFVGL LFIDSWKRSQ IRVSTYRNQK NPYIINSVTP VDALASRAYN
110 120 130 140 150
QRNVYISGFI IYFYICILTV MSILRRIVEW NDKMKAGDDI LKEKLRRKQK
160
YLEELQKKKF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z48502 Genomic DNA Translation: CAA88406.1 BK006946 Genomic DNA Translation: DAA09939.1 |
PIRi | S52889 |
RefSeqi | NP_013754.1, NM_001182537.1 |
Genome annotation databases
EnsemblFungii | YMR040W_mRNA; YMR040W; YMR040W |
GeneIDi | 855056 |
KEGGi | sce:YMR040W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z48502 Genomic DNA Translation: CAA88406.1 BK006946 Genomic DNA Translation: DAA09939.1 |
PIRi | S52889 |
RefSeqi | NP_013754.1, NM_001182537.1 |
3D structure databases
AlphaFoldDBi | Q04210 |
SMRi | Q04210 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 35212, 53 interactors |
STRINGi | 4932.YMR040W |
Proteomic databases
PaxDbi | Q04210 |
Genome annotation databases
EnsemblFungii | YMR040W_mRNA; YMR040W; YMR040W |
GeneIDi | 855056 |
KEGGi | sce:YMR040W |
Organism-specific databases
SGDi | S000004643, YET2 |
VEuPathDBi | FungiDB:YMR040W |
Phylogenomic databases
eggNOGi | KOG1962, Eukaryota |
GeneTreei | ENSGT00390000011863 |
HOGENOMi | CLU_087648_1_0_1 |
InParanoidi | Q04210 |
OMAi | EMAILFI |
Miscellaneous databases
PROi | PR:Q04210 |
RNActi | Q04210, protein |
Family and domain databases
InterProi | View protein in InterPro IPR008417, BAP29/BAP31 IPR040463, BAP29/BAP31_N |
PANTHERi | PTHR12701, PTHR12701, 1 hit |
Pfami | View protein in Pfam PF05529, Bap31, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YET2_YEAST | |
Accessioni | Q04210Primary (citable) accession number: Q04210 Secondary accession number(s): D6VZL5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | May 25, 2022 | |
This is version 118 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XIII
Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names - SIMILARITY comments
Index of protein domains and families