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UniProtKB - Q04162 (YD387_YEAST)
Protein
Probable metabolite transport protein YDR387C
Gene
YDR387C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
GO - Molecular functioni
- myo-inositol:proton symporter activity Source: GO_Central
- transmembrane transporter activity Source: SGD
GO - Biological processi
- carbohydrate transport Source: UniProtKB-KW
- transmembrane transport Source: SGD
Keywordsi
Biological process | Sugar transport, Transport |
Protein family/group databases
TCDBi | 2.A.1.1.101, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: Probable metabolite transport protein YDR387C |
Gene namesi | Ordered Locus Names:YDR387C |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000002795, YDR387C |
VEuPathDBi | FungiDB:YDR387C |
Subcellular locationi
Other locations
Vacuole
- fungal-type vacuole membrane Source: SGD
Other locations
- integral component of membrane Source: UniProtKB-KW
- membrane Source: SGD
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 39 | CytoplasmicSequence analysisAdd BLAST | 39 | |
Transmembranei | 40 – 60 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 61 – 83 | ExtracellularSequence analysisAdd BLAST | 23 | |
Transmembranei | 84 – 104 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 105 – 118 | CytoplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 119 – 139 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 140 | ExtracellularSequence analysis | 1 | |
Transmembranei | 141 – 161 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 162 – 168 | CytoplasmicSequence analysis | 7 | |
Transmembranei | 169 – 189 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 190 – 200 | ExtracellularSequence analysisAdd BLAST | 11 | |
Transmembranei | 201 – 221 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 222 – 356 | CytoplasmicSequence analysisAdd BLAST | 135 | |
Transmembranei | 357 – 377 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 378 – 384 | ExtracellularSequence analysis | 7 | |
Transmembranei | 385 – 405 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 406 – 413 | CytoplasmicSequence analysis | 8 | |
Transmembranei | 414 – 434 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 435 – 440 | ExtracellularSequence analysis | 6 | |
Transmembranei | 441 – 461 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 462 – 474 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 475 – 497 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 498 – 506 | ExtracellularSequence analysis | 9 | |
Transmembranei | 507 – 527 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 528 – 555 | CytoplasmicSequence analysisAdd BLAST | 28 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000252274 | 1 – 555 | Probable metabolite transport protein YDR387CAdd BLAST | 555 |
Proteomic databases
PaxDbi | Q04162 |
PTM databases
iPTMneti | Q04162 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 32448, 55 interactors |
DIPi | DIP-4084N |
STRINGi | 4932.YDR387C |
Miscellaneous databases
RNActi | Q04162, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 289 – 313 | DisorderedSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
GeneTreei | ENSGT00940000155870 |
HOGENOMi | CLU_001265_30_5_1 |
InParanoidi | Q04162 |
OMAi | CISCTNW |
Family and domain databases
Gene3Di | 1.20.1250.20, 2 hits |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 2 hits |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q04162-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTDESEDVY SDLYSIISQV TSNTANDIEQ LPYALTFKTS LIFVGATIGG
60 70 80 90 100
LLFGYDTGVI SGVLLSLKPE DLSLVVLTDV QKELITSSTS VGSFFGSILA
110 120 130 140 150
FPLADRYGRR ITLAICCSIF ILAAIGMAIA RTLTFLICGR LLVGIAVGVS
160 170 180 190 200
AQCVPLFLSE ISPSRIRGFM LTLNIIAITG GQLVSYVIAS LMKEIDNSWR
210 220 230 240 250
YLFALSAIPA ILFLSILDFI PESPRWSISK GDILYTRDSL RMLYPTASTY
260 270 280 290 300
HVNSKIKQLI IELDKLRLYE DASEPLLVQS QSVIRYMDSS TSGTLSPPNI
310 320 330 340 350
KRLSSNTERT SNTMSSSSAY LSALRGPAPN GALASNKKKR HRMEPRTIRA
360 370 380 390 400
LIVGCMLMFF QQITGFNAFM YYAAIIFSKF NIKNPLLPPI LIASTNFIFT
410 420 430 440 450
FFAMYTMDSL GRRAILLRTI LIMTVGLLLC SVGFGHDQVN LLLISVVIYV
460 470 480 490 500
AAYASAMGSV PWTCVEFLPL NRRSFGASCI ACTNWLTNAF VSMTYLSTIN
510 520 530 540 550
TIGDENTMLI FAFFTVCAWF FVYFWYPEVK GLSLEEVGRV FDNGIDVHYV
FRTYH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U32274 Genomic DNA Translation: AAB64829.1 BK006938 Genomic DNA Translation: DAA12231.1 |
PIRi | S69671 |
RefSeqi | NP_010675.3, NM_001180695.3 |
Genome annotation databases
EnsemblFungii | YDR387C_mRNA; YDR387C; YDR387C |
GeneIDi | 851995 |
KEGGi | sce:YDR387C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U32274 Genomic DNA Translation: AAB64829.1 BK006938 Genomic DNA Translation: DAA12231.1 |
PIRi | S69671 |
RefSeqi | NP_010675.3, NM_001180695.3 |
3D structure databases
AlphaFoldDBi | Q04162 |
SMRi | Q04162 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 32448, 55 interactors |
DIPi | DIP-4084N |
STRINGi | 4932.YDR387C |
Protein family/group databases
TCDBi | 2.A.1.1.101, the major facilitator superfamily (mfs) |
PTM databases
iPTMneti | Q04162 |
Proteomic databases
PaxDbi | Q04162 |
Genome annotation databases
EnsemblFungii | YDR387C_mRNA; YDR387C; YDR387C |
GeneIDi | 851995 |
KEGGi | sce:YDR387C |
Organism-specific databases
SGDi | S000002795, YDR387C |
VEuPathDBi | FungiDB:YDR387C |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
GeneTreei | ENSGT00940000155870 |
HOGENOMi | CLU_001265_30_5_1 |
InParanoidi | Q04162 |
OMAi | CISCTNW |
Miscellaneous databases
PROi | PR:Q04162 |
RNActi | Q04162, protein |
Family and domain databases
Gene3Di | 1.20.1250.20, 2 hits |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 2 hits |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YD387_YEAST | |
Accessioni | Q04162Primary (citable) accession number: Q04162 Secondary accession number(s): D6VT21 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 3, 2006 |
Last sequence update: | November 1, 1996 | |
Last modified: | May 25, 2022 | |
This is version 163 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome IV
Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names - SIMILARITY comments
Index of protein domains and families