prgX

Functionⁱ

GO - Molecular functionⁱ

sequence-specific DNA binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

negative regulation of transcription, DNA-templated
Source: CACAO
Inferred from direct assayⁱ
- 22544272

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingImported, ReceptorImported

Molecular function

DNA-bindingImported, ReceptorImported

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: DNA-binding proteinImported Submitted name: Pheromone cCF10 receptorImported Submitted name: PrgXImported
Gene namesⁱ	Name:prgXImported ORF Names:A6B47_14550Imported
Encoded onⁱ	Plasmid Efsorialis-p2Imported Plasmid efsorialis-p2Imported Plasmid pCF10Imported Plasmid pMG2200Imported
Organismⁱ	Enterococcus faecalis (Streptococcus faecalis)Imported
Taxonomic identifierⁱ	1351 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Terrabacteria group › Firmicutes › Bacilli › Lactobacillales › Enterococcaceae › Enterococcus
Proteomesⁱ	UP000196367 Componentⁱ: Plasmid efsorialis-p2

Subcellular locationⁱ

GO - Cellular componentⁱ

transcriptional repressor complex
Source: CACAO
Inferred from mutant phenotypeⁱ
- 22544272

View the complete GO annotation on QuickGO ...

Structureⁱ

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	7 – 61	HTH cro/C1-typeInterPro annotationAdd BLAST		55

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00093 HTH_XRE, 1 hit
InterProⁱ	View protein in InterPro IPR001387 Cro/C1-type_HTH IPR010982 Lambda_DNA-bd_dom_sf IPR011990 TPR-like_helical_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01381 HTH_3, 1 hit
SMARTⁱ	View protein in SMART SM00530 HTH_XRE, 1 hit
SUPFAMⁱ	SSF47413 SSF47413, 1 hit SSF48452 SSF48452, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q04114-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MFKIGSVLKQ IRQELNYHQI DLYSGIMSKS VYIKVEADSR PISVEELSKF 
        60         70         80         90        100
SERLGVNFFE ILNRAGMNTK SVNETGKEKL LISKIFTNPD LFDKNFQRIE 
       110        120        130        140        150
PKRLTSLQYF SIYLGYISIA HHYNIEVPTF NKTITSDLKH LYDKRTTFFG 
       160        170        180        190        200
IDYEIVSNLL NVLPYEEVSS IIKPMYPIVD SFGKDYDLTI QTVLKNALTI 
       210        220        230        240        250
SIMNRNLKEA QYYINQFEHL KTIKNISING YYDLEINYLK QIYQFLTDKN 
       260        270        280        290        300
IDSYLNAVNI INIFKIIGKE DIHRSLVEEL TKISAKEKFT PPKEVTMYYE 
       310 
NYVAIENNPI PEIKEQS

Length:317

Mass (Da):37,094

Last modified:November 1, 1996 - v1

Checksum:ⁱ411A62B678164A1D

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY855841 Genomic DNA Translation: AAA65845.1 CP015885 Genomic DNA Translation: ARV05114.1 AB374546 Genomic DNA Translation: BAH02409.1
PIRⁱ	B41662
NCBI Reference Sequences More...RefSeqⁱ	WP_002366018.1, NZ_PZZI01000004.1 YP_002333461.1, NC_011642.1 YP_195768.1, NC_006827.2

Genome annotation databases

GeneIDⁱ	3267197 7072416

GeneIDⁱ

3267197
7072416

Protein	Similar proteins		Species	Score	Length
Q04114	Transcriptional activator, Rgg/GadR/MutR family, C-terminal domain		CHLTH		317
DNA-binding helix-turn-helix protein		Enterococcus faecium SB2C-2		317
Uncharacterized protein		Enterococcus faecalis EnGen0354		317
DNA-binding helix-turn-helix protein		Enterococcus faecalis TX0411		317
DNA-binding helix-turn-helix protein		Enterococcus faecalis TX0027		317
+3

Protein	Similar proteins		Species	Score	Length
Q04114	Transcriptional activator, Rgg/GadR/MutR family, C-terminal domain		CHLTH		317
DNA-binding helix-turn-helix protein		Enterococcus faecium SB2C-2		317
Uncharacterized protein		Enterococcus faecalis EnGen0354		317
DNA-binding helix-turn-helix protein		Enterococcus faecalis TX0411		317
DNA-binding helix-turn-helix protein		Enterococcus faecalis TX0027		317
+21

Protein	Similar proteins		Species	Score	Length
Q04114	Transcriptional activator, Rgg/GadR/MutR family, C-terminal domain		CHLTH		317
DNA-binding helix-turn-helix protein		Enterococcus faecium SB2C-2		317
Uncharacterized protein		Enterococcus faecalis EnGen0354		317
DNA-binding helix-turn-helix protein		Enterococcus faecalis TX0411		317
DNA-binding helix-turn-helix protein		Enterococcus faecalis TX0027		317
+21

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY855841 Genomic DNA Translation: AAA65845.1 CP015885 Genomic DNA Translation: ARV05114.1 AB374546 Genomic DNA Translation: BAH02409.1
PIRⁱ	B41662
NCBI Reference Sequences More...RefSeqⁱ	WP_002366018.1, NZ_PZZI01000004.1 YP_002333461.1, NC_011642.1 YP_195768.1, NC_006827.2

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2AW6	X-ray	3.00	A/B	1-317	[»]
	2AWI	X-ray	2.25	A/B/C/D/E/F/G/H/I/J/K/L	1-317	[»]
	2AXU	X-ray	2.90	A/B/C/D/E/F/G/H/I/J/K/L	1-317	[»]
	2AXV	X-ray	3.00	A/B/C/D	1-317	[»]
	2AXZ	X-ray	3.00	A/B/C/D	1-317	[»]
	2GRL	X-ray	3.00	A/B/C/D	1-317	[»]
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	3267197 7072416

GeneIDⁱ

3267197
7072416

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00093 HTH_XRE, 1 hit
InterProⁱ	View protein in InterPro IPR001387 Cro/C1-type_HTH IPR010982 Lambda_DNA-bd_dom_sf IPR011990 TPR-like_helical_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01381 HTH_3, 1 hit
SMARTⁱ	View protein in SMART SM00530 HTH_XRE, 1 hit
SUPFAMⁱ	SSF47413 SSF47413, 1 hit SSF48452 SSF48452, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q04114_ENTFL
Accessionⁱ	Q04114Primary (citable) accession number: Q04114
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 1, 1996
	Last sequence update:	November 1, 1996
	Last modified:	July 18, 2018
	This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structureCombined sources, Complete proteomeImported, PlasmidImported

UniProtKB - Q04114 (Q04114_ENTFL)

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DNA-binding protein

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q04114 (Q04114_ENTFL)

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DNA-binding protein

prgX

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ