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UniProtKB - Q03924 (ZN117_HUMAN)

Entry version 174 (12 Aug 2020)
Sequence version 5 (05 Apr 2011)
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Protein

Zinc finger protein 117

Gene

ZNF117

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri109 – 131C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri137 – 159C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri165 – 187C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri193 – 215C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri221 – 243C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri249 – 271C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri277 – 299C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri305 – 327C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri333 – 355C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri361 – 383C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri389 – 411C2H2-type 11; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri417 – 439C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri445 – 467C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q03924

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 117
Alternative name(s):
Provirus-linked krueppel
Short name:
h-PLK
Zinc finger protein HPF9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF117
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000152926.14

Human Gene Nomenclature Database

More...HGNCi		HGNC:12897, ZNF117

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		194624, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q03924

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		109504726
51351

Open Targets

More...OpenTargetsi		ENSG00000152926

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA37486

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q03924, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF117

Domain mapping of disease mutations (DMDM)

More...DMDMi		327478609

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000474071 – 483Zinc finger protein 117Add BLAST483

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q03924

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q03924

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q03924

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q03924

PeptideAtlas

More...PeptideAtlasi		Q03924

PRoteomics IDEntifications database

More...PRIDEi		Q03924

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		58227

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q03924

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q03924

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed early during embryonic development.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000152926, Expressed in adrenal tissue and 218 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q03924, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q03924, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000152926, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		119493, 1 interactor

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000282869

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q03924, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q03924

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri109 – 131C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri137 – 159C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri165 – 187C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri193 – 215C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri221 – 243C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri249 – 271C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri277 – 299C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri305 – 327C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri333 – 355C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri361 – 383C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri389 – 411C2H2-type 11; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri417 – 439C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri445 – 467C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161765

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_44_5_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q03924

Identification of Orthologs from Complete Genome Data

More...OMAi		TFNTHKI

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q03924

TreeFam database of animal gene trees

More...TreeFami		TF342117

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 7 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 13 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q03924-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKRHEMVAKH LVMFYYFAQH LWPEQNIRDS FQKVTLRRYR KCGYENLQLR 
        60         70         80         90        100
KGCKSVVECK QHKGDYSGLN QCLKTTLSKI FQCNKYVEVF HKISNSNRHK 
       110        120        130        140        150
MRHTENKHFK CKECRKTFCM LSHLTQHKRI QTRVNFYKCE AYGRAFNWSS 
       160        170        180        190        200
TLNKHKRIHT GEKPYKCKEC GKAFNQTSHL IRHKRIHTEE KPYKCEECGK 
       210        220        230        240        250
AFNQSSTLTT HNIIHTGEIP YKCEKCVRAF NQASKLTEHK LIHTGEKRYE 
       260        270        280        290        300
CEECGKAFNR SSKLTEHKYI HTGEKLYKCE ECGKAFNQSS TLTTHKRIHS 
       310        320        330        340        350
GEKPYKCEEC GKAFKQFSNL TDHKKIHTGE KPYKCEECGK AFNQLSNLTR 
       360        370        380        390        400
HKVIHTGEKP YKCGECGKAF NQSSALNTHK IIHTGENPHK CRESGKVFHL 
       410        420        430        440        450
SSKLSTCKKI HTGEKLYKCE ECGKAFNRSS TLIGHKRIHT GEKPYKCEEC 
       460        470        480 
GKAFNQSSTL TTHKIIHTEE KQYKCDECGK AST
Length:483
Mass (Da):56,376
Last modified:April 5, 2011 - v5
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE2729363C0E68C8E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087X2A5A0A087X2A5_HUMAN
Zinc finger protein 117
ZNF117
383Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAA36010 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated
The sequence AAA58666 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence AAG41761 differs from that shown. Aberrant splicing.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti40R → G in AAA58666 (PubMed:2023909).Curated1
Sequence conflicti43 – 44GY → RH in AAA58666 (PubMed:2023909).Curated2
Sequence conflicti131Q → H in AAG41761 (PubMed:2505992).Curated1
Sequence conflicti131Q → H in AAA58666 (PubMed:2023909).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05739683C → Y. Corresponds to variant dbSNP:rs3807069Ensembl.1
Natural variantiVAR_057397112K → N. Corresponds to variant dbSNP:rs3807068Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
M27879 mRNA Translation: AAG41761.1 Sequence problems.
M55422 mRNA Translation: AAA36010.1 Sequence problems.
AC073210 Genomic DNA No translation available.
M61867 mRNA Translation: AAA58666.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS43593.1

Protein sequence database of the Protein Information Resource

More...PIRi		A35659
B39384

NCBI Reference Sequences

More...RefSeqi		NP_001334979.1, NM_001348050.1
NP_056936.2, NM_015852.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000282869; ENSP00000282869; ENSG00000152926
ENST00000620222; ENSP00000479944; ENSG00000152926

Database of genes from NCBI RefSeq genomes

More...GeneIDi		109504726
51351

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:109504726
hsa:51351

UCSC genome browser

More...UCSCi		uc003ttr.3, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M27879 mRNA Translation: AAG41761.1 Sequence problems.
M55422 mRNA Translation: AAA36010.1 Sequence problems.
AC073210 Genomic DNA No translation available.
M61867 mRNA Translation: AAA58666.1 Different initiation.
CCDSiCCDS43593.1
PIRiA35659
B39384
RefSeqiNP_001334979.1, NM_001348050.1
NP_056936.2, NM_015852.3

3D structure databases

SMRiQ03924
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi119493, 1 interactor
STRINGi9606.ENSP00000282869

PTM databases

iPTMnetiQ03924
PhosphoSitePlusiQ03924

Polymorphism and mutation databases

BioMutaiZNF117
DMDMi327478609

Proteomic databases

jPOSTiQ03924
MassIVEiQ03924
MaxQBiQ03924
PaxDbiQ03924
PeptideAtlasiQ03924
PRIDEiQ03924
ProteomicsDBi58227

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		28146, 94 antibodies

The DNASU plasmid repository

More...DNASUi		51351

Genome annotation databases

EnsembliENST00000282869; ENSP00000282869; ENSG00000152926
ENST00000620222; ENSP00000479944; ENSG00000152926
GeneIDi109504726
51351
KEGGihsa:109504726
hsa:51351
UCSCiuc003ttr.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		109504726
51351
DisGeNETi109504726
51351
EuPathDBiHostDB:ENSG00000152926.14

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF117
HGNCiHGNC:12897, ZNF117
HPAiENSG00000152926, Low tissue specificity
MIMi194624, gene
neXtProtiNX_Q03924
OpenTargetsiENSG00000152926
PharmGKBiPA37486

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000161765
HOGENOMiCLU_002678_44_5_1
InParanoidiQ03924
OMAiTFNTHKI
OrthoDBi1318335at2759
PhylomeDBiQ03924
TreeFamiTF342117

Enzyme and pathway databases

PathwayCommonsiQ03924

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		51351, 4 hits in 873 CRISPR screens
PharosiQ03924, Tdark

Protein Ontology

More...PROi		PR:Q03924
RNActiQ03924, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000152926, Expressed in adrenal tissue and 218 other tissues
ExpressionAtlasiQ03924, baseline and differential
GenevisibleiQ03924, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 10 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 12 hits
SUPFAMiSSF57667, SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 13 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN117_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q03924
Secondary accession number(s): Q02313, Q7Z7Q7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: April 5, 2011
Last modified: August 12, 2020
This is version 174 of the entry and version 5 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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